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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 12447

FusionGeneSummary for FAIM_SLAIN1

check button Fusion gene summary
Fusion gene informationFusion gene name: FAIM_SLAIN1
Fusion gene ID: 12447
HgeneTgene
Gene symbol

FAIM

SLAIN1

Gene ID

55179

122060

Gene nameFas apoptotic inhibitory moleculeSLAIN motif family member 1
SynonymsFAIM1C13orf32
Cytomap

3q22.3

13q22.3

Type of geneprotein-codingprotein-coding
Descriptionfas apoptotic inhibitory molecule 1SLAIN motif-containing protein 1
Modification date2018051920180519
UniProtAcc

Q9NVQ4

Q8ND83

Ensembl transtripts involved in fusion geneENST00000338446, ENST00000360570, 
ENST00000393035, ENST00000393034, 
ENST00000464668, 
ENST00000466548, 
ENST00000418532, ENST00000488699, 
ENST00000267219, ENST00000351546, 
ENST00000465831, ENST00000314070, 
ENST00000358679, 
Fusion gene scores* DoF score1 X 1 X 1=14 X 4 X 2=32
# samples 14
** MAII scorelog2(1/1*10)=3.32192809488736log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: FAIM [Title/Abstract] AND SLAIN1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1W07321FAIMchr3

138352063

-SLAIN1chr13

78320728

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000338446ENST00000466548FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000338446ENST00000418532FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000338446ENST00000488699FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000338446ENST00000267219FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000338446ENST00000351546FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3UTRENST00000338446ENST00000465831FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000338446ENST00000314070FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000338446ENST00000358679FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000360570ENST00000466548FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000360570ENST00000418532FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000360570ENST00000488699FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000360570ENST00000267219FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000360570ENST00000351546FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3UTRENST00000360570ENST00000465831FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000360570ENST00000314070FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000360570ENST00000358679FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393035ENST00000466548FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393035ENST00000418532FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393035ENST00000488699FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393035ENST00000267219FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393035ENST00000351546FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3UTRENST00000393035ENST00000465831FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000393035ENST00000314070FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000393035ENST00000358679FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393034ENST00000466548FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393034ENST00000418532FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393034ENST00000488699FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393034ENST00000267219FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3CDSENST00000393034ENST00000351546FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-3UTRENST00000393034ENST00000465831FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000393034ENST00000314070FAIMchr3

138352063

-SLAIN1chr13

78320728

-
3UTR-intronENST00000393034ENST00000358679FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-3CDSENST00000464668ENST00000466548FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-3CDSENST00000464668ENST00000418532FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-3CDSENST00000464668ENST00000488699FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-3CDSENST00000464668ENST00000267219FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-3CDSENST00000464668ENST00000351546FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-3UTRENST00000464668ENST00000465831FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-intronENST00000464668ENST00000314070FAIMchr3

138352063

-SLAIN1chr13

78320728

-
intron-intronENST00000464668ENST00000358679FAIMchr3

138352063

-SLAIN1chr13

78320728

-

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FusionProtFeatures for FAIM_SLAIN1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FAIM

Q9NVQ4

SLAIN1

Q8ND83