|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 12301 |
FusionGeneSummary for EXOC7_NAP1L1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EXOC7_NAP1L1 | Fusion gene ID: 12301 | Hgene | Tgene | Gene symbol | EXOC7 | NAP1L1 | Gene ID | 23265 | 4673 |
| Gene name | exocyst complex component 7 | nucleosome assembly protein 1 like 1 | |
| Synonyms | 2-5-3p|BLOM4|EX070|EXO70|EXOC1|Exo70p|YJL085W | NAP1|NAP1L|NRP | |
| Cytomap | 17q25.1 | 12q21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | exocyst complex component 7exocyst complex component Exo70 | nucleosome assembly protein 1-like 1HSP22-like protein interacting proteinNAP-1-related protein | |
| Modification date | 20180522 | 20180522 | |
| UniProtAcc | Q9UPT5 | P55209 | |
| Ensembl transtripts involved in fusion gene | ENST00000607838, ENST00000591724, ENST00000332065, ENST00000589210, ENST00000335146, ENST00000467929, ENST00000405575, ENST00000411744, ENST00000406660, | ENST00000261182, ENST00000393263, ENST00000431879, ENST00000547773, ENST00000544816, ENST00000542344, ENST00000535020, ENST00000549596, ENST00000547993, ENST00000552342, ENST00000548044, | |
| Fusion gene scores | * DoF score | 9 X 9 X 4=324 | 6 X 7 X 2=84 |
| # samples | 11 | 10 | |
| ** MAII score | log2(11/324*10)=-1.55849028935997 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/84*10)=0.251538766995964 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: EXOC7 [Title/Abstract] AND NAP1L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF804799 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - | ||
| ChiTaRS3.1 | BF804803 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - | ||
| ChiTaRS3.1 | BF756411 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000607838 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000607838 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000607838 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000607838 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000607838 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000591724 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000591724 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000591724 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000591724 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000591724 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000332065 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000332065 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000332065 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000332065 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000332065 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000589210 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000589210 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000589210 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000589210 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000589210 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000335146 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000335146 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000335146 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000335146 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000335146 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000467929 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000467929 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000467929 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000467929 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000467929 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000405575 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000405575 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000405575 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000405575 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000405575 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000411744 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000411744 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000411744 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000411744 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000411744 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000406660 | ENST00000261182 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000406660 | ENST00000393263 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000406660 | ENST00000431879 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-3CDS | ENST00000406660 | ENST00000547773 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000544816 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000542344 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000535020 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000549596 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000547993 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000552342 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
| intron-5UTR | ENST00000406660 | ENST00000548044 | EXOC7 | chr17 | 74078906 | - | NAP1L1 | chr12 | 76449919 | - |
Top |
FusionProtFeatures for EXOC7_NAP1L1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EXOC7 | NAP1L1 |