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Fusion gene ID: 11662 |
FusionGeneSummary for ENTPD5_NUBPL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ENTPD5_NUBPL | Fusion gene ID: 11662 | Hgene | Tgene | Gene symbol | ENTPD5 | NUBPL | Gene ID | 957 | 80224 |
| Gene name | ectonucleoside triphosphate diphosphohydrolase 5 | nucleotide binding protein like | |
| Synonyms | CD39L4|NTPDase-5|PCPH | C14orf127|IND1|huInd1 | |
| Cytomap | 14q24.3 | 14q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ectonucleoside triphosphate diphosphohydrolase 5CD39 antigen-like 4CD39-like 4ER-UDPaseGDPase ENTPD5NTPDase 5Pcph proto-oncogene proteinUDPase ENTPD5guanosine-diphosphatase ENTPD5nucleoside diphosphataseproto-oncogene CPHuridine-diphosphatase E | iron-sulfur protein NUBPLIND1 homologiron-sulfur protein required for NADH dehydrogenase | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O75356 | Q8TB37 | |
| Ensembl transtripts involved in fusion gene | ENST00000557325, ENST00000334696, ENST00000556242, ENST00000554664, | ENST00000281081, ENST00000536705, ENST00000418681, | |
| Fusion gene scores | * DoF score | 7 X 4 X 6=168 | 8 X 5 X 6=240 |
| # samples | 7 | 8 | |
| ** MAII score | log2(7/168*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ENTPD5 [Title/Abstract] AND NUBPL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-DK-A3IK-01A | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000557325 | ENST00000281081 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| Frame-shift | ENST00000557325 | ENST00000536705 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| 5CDS-3UTR | ENST00000557325 | ENST00000418681 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| Frame-shift | ENST00000334696 | ENST00000281081 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| Frame-shift | ENST00000334696 | ENST00000536705 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| 5CDS-3UTR | ENST00000334696 | ENST00000418681 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| intron-3CDS | ENST00000556242 | ENST00000281081 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| intron-3CDS | ENST00000556242 | ENST00000536705 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| intron-3UTR | ENST00000556242 | ENST00000418681 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| intron-3CDS | ENST00000554664 | ENST00000281081 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| intron-3CDS | ENST00000554664 | ENST00000536705 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
| intron-3UTR | ENST00000554664 | ENST00000418681 | ENTPD5 | chr14 | 74436713 | - | NUBPL | chr14 | 32295835 | + |
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FusionProtFeatures for ENTPD5_NUBPL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ENTPD5 | NUBPL |