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Fusion gene ID: 11471 |
FusionGeneSummary for ELMSAN1_NUMB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ELMSAN1_NUMB | Fusion gene ID: 11471 | Hgene | Tgene | Gene symbol | ELMSAN1 | NUMB | Gene ID | 91748 | 8650 |
| Gene name | ELM2 and Myb/SANT domain containing 1 | NUMB, endocytic adaptor protein | |
| Synonyms | C14orf117|C14orf43|LSR68|MIDEAS|c14_5541 | C14orf41|S171|c14_5527 | |
| Cytomap | 14q24.3 | 14q24.2-q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ELM2 and SANT domain-containing protein 1ELM2 and Myb/SANT-like domain containing 1 | protein numb homologh-Numbnumb homolog | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q6PJG2 | P49757 | |
| Ensembl transtripts involved in fusion gene | ENST00000394071, ENST00000286523, ENST00000486739, | ENST00000554546, ENST00000356296, ENST00000557597, ENST00000555238, ENST00000355058, ENST00000359560, ENST00000555394, ENST00000454166, ENST00000544991, ENST00000560335, ENST00000555738, ENST00000559312, ENST00000554521, ENST00000535282, ENST00000556600, ENST00000556772, | |
| Fusion gene scores | * DoF score | 11 X 7 X 7=539 | 2 X 2 X 2=8 |
| # samples | 12 | 2 | |
| ** MAII score | log2(12/539*10)=-2.16725086714399 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: ELMSAN1 [Title/Abstract] AND NUMB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | CESC | TCGA-VS-A953-01A | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000394071 | ENST00000554546 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000356296 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000557597 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000555238 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000355058 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000359560 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000555394 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000454166 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000544991 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000560335 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000555738 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000559312 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000554521 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000535282 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000556600 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000394071 | ENST00000556772 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000554546 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000356296 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000557597 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000555238 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000355058 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000359560 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000555394 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000454166 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000544991 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000560335 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000555738 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000559312 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000554521 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000535282 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000556600 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| 5CDS-intron | ENST00000286523 | ENST00000556772 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000554546 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000356296 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000557597 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000555238 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000355058 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000359560 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000555394 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000454166 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000544991 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000560335 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000555738 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000559312 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000554521 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000535282 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000556600 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
| intron-intron | ENST00000486739 | ENST00000556772 | ELMSAN1 | chr14 | 74203701 | - | NUMB | chr14 | 73926011 | - |
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FusionProtFeatures for ELMSAN1_NUMB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ELMSAN1 | NUMB |