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Fusion gene ID: 11157 |
FusionGeneSummary for EHD4_TEX41 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EHD4_TEX41 | Fusion gene ID: 11157 | Hgene | Tgene | Gene symbol | EHD4 | TEX41 | Gene ID | 30844 | 401014 |
| Gene name | EH domain containing 4 | testis expressed 41 | |
| Synonyms | PAST4 | DKFZp686O1327|LINC00953 | |
| Cytomap | 15q15.1 | 2q22.3 | |
| Type of gene | protein-coding | ncRNA | |
| Description | EH domain-containing protein 4PAST homolog 4hepatocellular carcinoma-associated protein 10/11hepatocellular carcinoma-associated protein HCA11ortholog of rat pincher | long intergenic non-protein coding RNA 953testis expressed 41 (non-protein coding) | |
| Modification date | 20180522 | 20180517 | |
| UniProtAcc | Q9H223 | ||
| Ensembl transtripts involved in fusion gene | ENST00000220325, | ENST00000445791, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 2 X 1 X 2=4 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: EHD4 [Title/Abstract] AND TEX41 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A8BK-01A | EHD4 | chr15 | 42264457 | - | TEX41 | chr2 | 145939771 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000220325 | ENST00000445791 | EHD4 | chr15 | 42264457 | - | TEX41 | chr2 | 145939771 | + |
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FusionProtFeatures for EHD4_TEX41 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EHD4 | TEX41 |