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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for NDRG2 |
 Gene summary |
| Gene information | Gene symbol | NDRG2 | Gene ID | 57447 |
| Gene name | NDRG family member 2 | |
| Synonyms | SYLD | |
| Cytomap | 14q11.2 | |
| Type of gene | protein-coding | |
| Description | protein NDRG2N-myc downstream regulator 2N-myc downstream-regulated gene 2 proteinNDR1-related protein NDR2cytoplasmic protein Ndr1syld709613 protein | |
| Modification date | 20180523 | |
| UniProtAcc | Q9UN36 | |
| Context | PubMed: NDRG2 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for NDRG2 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for NDRG2 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for NDRG2 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_111028 | 14 | 21486178:21486197:21486362:21486398:21486615:21486630 | 21486362:21486398 | ENSG00000165795.16 | ENST00000397858.1,ENST00000298687.5,ENST00000554104.1,ENST00000557353.1,ENST00000298684.5,ENST00000556147.1,ENST00000556008.1,ENST00000397847.2,ENST00000555158.1,ENST00000553793.1,ENST00000403829.3,ENST00000360463.3,ENST00000556366.1,ENST00000554143.1,ENS |
| exon_skip_111032 | 14 | 21486362:21486398:21486615:21486663:21486921:21486973 | 21486615:21486663 | ENSG00000165795.16 | ENST00000397858.1,ENST00000298687.5,ENST00000554104.1,ENST00000557353.1,ENST00000298684.5,ENST00000556147.1,ENST00000556008.1,ENST00000555158.1,ENST00000553793.1,ENST00000403829.3,ENST00000360463.3,ENST00000556366.1,ENST00000554143.1,ENST00000397855.3,ENS |
| exon_skip_111039 | 14 | 21486615:21486663:21486785:21486822:21486921:21486973 | 21486785:21486822 | ENSG00000165795.16 | ENST00000557416.1 |
| exon_skip_111047 | 14 | 21487856:21487901:21488078:21488135:21488654:21488741 | 21488078:21488135 | ENSG00000165795.16 | ENST00000397858.1,ENST00000555869.1,ENST00000298687.5,ENST00000554104.1,ENST00000557353.1,ENST00000556147.1,ENST00000397856.3,ENST00000557182.1,ENST00000556008.1,ENST00000397847.2,ENST00000555733.1,ENST00000555695.1,ENST00000397844.2,ENST00000555158.1,ENS |
| exon_skip_111049 | 14 | 21488125:21488135:21488654:21488741:21488942:21489003 | 21488654:21488741 | ENSG00000165795.16 | ENST00000397858.1,ENST00000555869.1,ENST00000298687.5,ENST00000554104.1,ENST00000557353.1,ENST00000556147.1,ENST00000554094.1,ENST00000397856.3,ENST00000557182.1,ENST00000556008.1,ENST00000397847.2,ENST00000555733.1,ENST00000555695.1,ENST00000397844.2,ENS |
| exon_skip_111053 | 14 | 21490220:21490324:21490550:21490656:21491399:21491480 | 21490550:21490656 | ENSG00000165795.16 | ENST00000557353.1,ENST00000553563.1 |
| exon_skip_111056 | 14 | 21490305:21490341:21490550:21490656:21491022:21491064 | 21490550:21490656 | ENSG00000165795.16 | ENST00000397858.1,ENST00000298687.5,ENST00000556147.1,ENST00000554472.1,ENST00000554415.1,ENST00000554531.1,ENST00000557318.1,ENST00000397847.2,ENST00000555733.1,ENST00000553741.1,ENST00000555695.1,ENST00000556457.1,ENST00000555384.1,ENST00000554398.1,ENS |
| exon_skip_111057 | 14 | 21490305:21490341:21490550:21490656:21491399:21491480 | 21490550:21490656 | ENSG00000165795.16 | ENST00000555869.1,ENST00000554379.1,ENST00000557198.1,ENST00000554893.1,ENST00000298684.5,ENST00000554094.1,ENST00000397856.3,ENST00000557113.1,ENST00000556329.2,ENST00000557616.1,ENST00000553900.1,ENST00000556008.1,ENST00000557264.1,ENST00000397844.2,ENS |
| exon_skip_111063 | 14 | 21490550:21490656:21491022:21491064:21491399:21491480 | 21491022:21491064 | ENSG00000165795.16 | ENST00000397858.1,ENST00000298687.5,ENST00000556147.1,ENST00000554472.1,ENST00000554415.1,ENST00000557318.1,ENST00000397847.2,ENST00000555733.1,ENST00000553741.1,ENST00000555695.1,ENST00000556457.1,ENST00000555384.1,ENST00000554398.1,ENST00000556688.1,ENS |
| exon_skip_111067 | 14 | 21490550:21490656:21491399:21491480:21493187:21493206 | 21491399:21491480 | ENSG00000165795.16 | ENST00000554379.1,ENST00000557198.1,ENST00000557353.1,ENST00000554143.1 |
| exon_skip_111074 | 14 | 21491399:21491480:21492134:21492255:21493187:21493206 | 21492134:21492255 | ENSG00000165795.16 | ENST00000554483.1 |
| exon_skip_111095 | 14 | 21491399:21491480:21492144:21492255:21492984:21493159 | 21492144:21492255 | ENSG00000165795.16 | ENST00000555158.1 |
| exon_skip_111097 | 14 | 21491399:21491480:21492144:21492255:21493007:21493192 | 21492144:21492255 | ENSG00000165795.16 | ENST00000554893.1 |
| exon_skip_111098 | 14 | 21491399:21491480:21492144:21492255:21493187:21493206 | 21492144:21492255 | ENSG00000165795.16 | ENST00000556329.2,ENST00000556688.1 |
| exon_skip_111102 | 14 | 21491399:21491480:21492144:21492255:21493629:21493649 | 21492144:21492255 | ENSG00000165795.16 | ENST00000553442.1 |
| exon_skip_111104 | 14 | 21491399:21491480:21492144:21492255:21493835:21493891 | 21492144:21492255 | ENSG00000165795.16 | ENST00000554419.1,ENST00000556974.1 |
| exon_skip_111105 | 14 | 21491399:21491480:21492188:21492255:21492984:21493159 | 21492188:21492255 | ENSG00000165795.16 | ENST00000554489.1,ENST00000554833.1 |
| exon_skip_111107 | 14 | 21491399:21491480:21492188:21492255:21493007:21493192 | 21492188:21492255 | ENSG00000165795.16 | ENST00000555733.1,ENST00000553503.1 |
| exon_skip_111108 | 14 | 21491399:21491480:21492188:21492255:21493187:21493206 | 21492188:21492255 | ENSG00000165795.16 | ENST00000397856.3,ENST00000557616.1,ENST00000553900.1,ENST00000397855.3,ENST00000553867.1,ENST00000557676.1,ENST00000397853.3 |
| exon_skip_111109 | 14 | 21491399:21491480:21492188:21492255:21493222:21493298 | 21492188:21492255 | ENSG00000165795.16 | ENST00000555142.1 |
| exon_skip_111111 | 14 | 21491399:21491480:21492188:21492255:21493552:21493685 | 21492188:21492255 | ENSG00000165795.16 | ENST00000555869.1,ENST00000397844.2,ENST00000556457.1,ENST00000555767.1 |
| exon_skip_111112 | 14 | 21491399:21491480:21492188:21492255:21493629:21493649 | 21492188:21492255 | ENSG00000165795.16 | ENST00000554415.1 |
| exon_skip_111114 | 14 | 21491399:21491480:21492188:21492255:21493835:21493891 | 21492188:21492255 | ENSG00000165795.16 | ENST00000350792.3 |
| exon_skip_111115 | 14 | 21491399:21491480:21492188:21492298:21493187:21493220 | 21492188:21492298 | ENSG00000165795.16 | ENST00000556008.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for NDRG2 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_111028 | 14 | 21486178:21486197:21486362:21486398:21486615:21486630 | 21486362:21486398 | ENSG00000165795.16 | ENST00000298687.5,ENST00000350792.3,ENST00000397858.1,ENST00000554104.1,ENST00000555158.1,ENST00000553503.1,ENST00000397853.3,ENST00000360463.3,ENST00000556147.1,ENST00000557353.1,ENST00000554143.1,ENST00000397851.2,ENST00000397847.2,ENST00000397855.3,ENS |
| exon_skip_111032 | 14 | 21486362:21486398:21486615:21486663:21486921:21486973 | 21486615:21486663 | ENSG00000165795.16 | ENST00000298687.5,ENST00000350792.3,ENST00000397858.1,ENST00000554104.1,ENST00000555158.1,ENST00000553503.1,ENST00000397853.3,ENST00000360463.3,ENST00000556147.1,ENST00000557353.1,ENST00000554143.1,ENST00000397851.2,ENST00000397855.3,ENST00000298684.5,ENS |
| exon_skip_111039 | 14 | 21486615:21486663:21486785:21486822:21486921:21486973 | 21486785:21486822 | ENSG00000165795.16 | ENST00000557416.1 |
| exon_skip_111047 | 14 | 21487856:21487901:21488078:21488135:21488654:21488741 | 21488078:21488135 | ENSG00000165795.16 | ENST00000298687.5,ENST00000350792.3,ENST00000397858.1,ENST00000554104.1,ENST00000555158.1,ENST00000553503.1,ENST00000397853.3,ENST00000360463.3,ENST00000556147.1,ENST00000557353.1,ENST00000554143.1,ENST00000397851.2,ENST00000397847.2,ENST00000397856.3,ENS |
| exon_skip_111049 | 14 | 21488125:21488135:21488654:21488741:21488942:21489003 | 21488654:21488741 | ENSG00000165795.16 | ENST00000298687.5,ENST00000350792.3,ENST00000397858.1,ENST00000554104.1,ENST00000555158.1,ENST00000553503.1,ENST00000397853.3,ENST00000360463.3,ENST00000556147.1,ENST00000557353.1,ENST00000554143.1,ENST00000397851.2,ENST00000397847.2,ENST00000397856.3,ENS |
| exon_skip_111053 | 14 | 21490220:21490324:21490550:21490656:21491399:21491480 | 21490550:21490656 | ENSG00000165795.16 | ENST00000557353.1,ENST00000553563.1 |
| exon_skip_111056 | 14 | 21490305:21490341:21490550:21490656:21491022:21491064 | 21490550:21490656 | ENSG00000165795.16 | ENST00000298687.5,ENST00000397858.1,ENST00000397853.3,ENST00000556147.1,ENST00000397851.2,ENST00000397847.2,ENST00000553867.1,ENST00000555695.1,ENST00000555733.1,ENST00000555384.1,ENST00000553741.1,ENST00000553784.1,ENST00000554531.1,ENST00000554398.1,ENS |
| exon_skip_111057 | 14 | 21490305:21490341:21490550:21490656:21491399:21491480 | 21490550:21490656 | ENSG00000165795.16 | ENST00000350792.3,ENST00000555158.1,ENST00000553503.1,ENST00000360463.3,ENST00000554143.1,ENST00000397856.3,ENST00000397855.3,ENST00000298684.5,ENST00000397844.2,ENST00000403829.3,ENST00000556008.1,ENST00000556974.1,ENST00000555026.1,ENST00000557169.1,ENS |
| exon_skip_111063 | 14 | 21490550:21490656:21491022:21491064:21491399:21491480 | 21491022:21491064 | ENSG00000165795.16 | ENST00000298687.5,ENST00000397858.1,ENST00000397853.3,ENST00000556147.1,ENST00000397851.2,ENST00000397847.2,ENST00000553867.1,ENST00000555695.1,ENST00000555733.1,ENST00000555384.1,ENST00000553741.1,ENST00000553784.1,ENST00000554398.1,ENST00000554472.1,ENS |
| exon_skip_111067 | 14 | 21490550:21490656:21491399:21491480:21493187:21493206 | 21491399:21491480 | ENSG00000165795.16 | ENST00000557353.1,ENST00000554143.1,ENST00000557198.1,ENST00000554379.1 |
| exon_skip_111074 | 14 | 21491399:21491480:21492134:21492255:21493187:21493206 | 21492134:21492255 | ENSG00000165795.16 | ENST00000554483.1 |
| exon_skip_111095 | 14 | 21491399:21491480:21492144:21492255:21492984:21493159 | 21492144:21492255 | ENSG00000165795.16 | ENST00000555158.1 |
| exon_skip_111097 | 14 | 21491399:21491480:21492144:21492255:21493007:21493192 | 21492144:21492255 | ENSG00000165795.16 | ENST00000554893.1 |
| exon_skip_111098 | 14 | 21491399:21491480:21492144:21492255:21493187:21493206 | 21492144:21492255 | ENSG00000165795.16 | ENST00000556329.2,ENST00000556688.1 |
| exon_skip_111102 | 14 | 21491399:21491480:21492144:21492255:21493629:21493649 | 21492144:21492255 | ENSG00000165795.16 | ENST00000553442.1 |
| exon_skip_111104 | 14 | 21491399:21491480:21492144:21492255:21493835:21493891 | 21492144:21492255 | ENSG00000165795.16 | ENST00000556974.1,ENST00000554419.1 |
| exon_skip_111105 | 14 | 21491399:21491480:21492188:21492255:21492984:21493159 | 21492188:21492255 | ENSG00000165795.16 | ENST00000554489.1,ENST00000554833.1 |
| exon_skip_111107 | 14 | 21491399:21491480:21492188:21492255:21493007:21493192 | 21492188:21492255 | ENSG00000165795.16 | ENST00000553503.1,ENST00000555733.1 |
| exon_skip_111108 | 14 | 21491399:21491480:21492188:21492255:21493187:21493206 | 21492188:21492255 | ENSG00000165795.16 | ENST00000397853.3,ENST00000397856.3,ENST00000397855.3,ENST00000553867.1,ENST00000557676.1,ENST00000557616.1,ENST00000553900.1 |
| exon_skip_111109 | 14 | 21491399:21491480:21492188:21492255:21493222:21493298 | 21492188:21492255 | ENSG00000165795.16 | ENST00000555142.1 |
| exon_skip_111111 | 14 | 21491399:21491480:21492188:21492255:21493552:21493685 | 21492188:21492255 | ENSG00000165795.16 | ENST00000397844.2,ENST00000555869.1,ENST00000555767.1,ENST00000556457.1 |
| exon_skip_111112 | 14 | 21491399:21491480:21492188:21492255:21493629:21493649 | 21492188:21492255 | ENSG00000165795.16 | ENST00000554415.1 |
| exon_skip_111114 | 14 | 21491399:21491480:21492188:21492255:21493835:21493891 | 21492188:21492255 | ENSG00000165795.16 | ENST00000350792.3 |
| exon_skip_111115 | 14 | 21491399:21491480:21492188:21492298:21493187:21493220 | 21492188:21492298 | ENSG00000165795.16 | ENST00000556008.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for NDRG2 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000397853 | 21492188 | 21492255 | 3UTR-3UTR |
| ENST00000298687 | 21490550 | 21490656 | Frame-shift |
| ENST00000397851 | 21490550 | 21490656 | Frame-shift |
| ENST00000397853 | 21490550 | 21490656 | Frame-shift |
| ENST00000397858 | 21490550 | 21490656 | Frame-shift |
| ENST00000556147 | 21490550 | 21490656 | Frame-shift |
| ENST00000298687 | 21486362 | 21486398 | In-frame |
| ENST00000397851 | 21486362 | 21486398 | In-frame |
| ENST00000397853 | 21486362 | 21486398 | In-frame |
| ENST00000397858 | 21486362 | 21486398 | In-frame |
| ENST00000556147 | 21486362 | 21486398 | In-frame |
| ENST00000298687 | 21486615 | 21486663 | In-frame |
| ENST00000397851 | 21486615 | 21486663 | In-frame |
| ENST00000397853 | 21486615 | 21486663 | In-frame |
| ENST00000397858 | 21486615 | 21486663 | In-frame |
| ENST00000556147 | 21486615 | 21486663 | In-frame |
| ENST00000298687 | 21488078 | 21488135 | In-frame |
| ENST00000397851 | 21488078 | 21488135 | In-frame |
| ENST00000397853 | 21488078 | 21488135 | In-frame |
| ENST00000397858 | 21488078 | 21488135 | In-frame |
| ENST00000556147 | 21488078 | 21488135 | In-frame |
| ENST00000298687 | 21488654 | 21488741 | In-frame |
| ENST00000397851 | 21488654 | 21488741 | In-frame |
| ENST00000397853 | 21488654 | 21488741 | In-frame |
| ENST00000397858 | 21488654 | 21488741 | In-frame |
| ENST00000556147 | 21488654 | 21488741 | In-frame |
| ENST00000298687 | 21491022 | 21491064 | In-frame |
| ENST00000397851 | 21491022 | 21491064 | In-frame |
| ENST00000397853 | 21491022 | 21491064 | In-frame |
| ENST00000397858 | 21491022 | 21491064 | In-frame |
| ENST00000556147 | 21491022 | 21491064 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000397853 | 21492188 | 21492255 | 3UTR-3UTR |
| ENST00000298687 | 21490550 | 21490656 | Frame-shift |
| ENST00000397851 | 21490550 | 21490656 | Frame-shift |
| ENST00000397853 | 21490550 | 21490656 | Frame-shift |
| ENST00000397858 | 21490550 | 21490656 | Frame-shift |
| ENST00000556147 | 21490550 | 21490656 | Frame-shift |
| ENST00000298687 | 21486362 | 21486398 | In-frame |
| ENST00000397851 | 21486362 | 21486398 | In-frame |
| ENST00000397853 | 21486362 | 21486398 | In-frame |
| ENST00000397858 | 21486362 | 21486398 | In-frame |
| ENST00000556147 | 21486362 | 21486398 | In-frame |
| ENST00000298687 | 21486615 | 21486663 | In-frame |
| ENST00000397851 | 21486615 | 21486663 | In-frame |
| ENST00000397853 | 21486615 | 21486663 | In-frame |
| ENST00000397858 | 21486615 | 21486663 | In-frame |
| ENST00000556147 | 21486615 | 21486663 | In-frame |
| ENST00000298687 | 21488078 | 21488135 | In-frame |
| ENST00000397851 | 21488078 | 21488135 | In-frame |
| ENST00000397853 | 21488078 | 21488135 | In-frame |
| ENST00000397858 | 21488078 | 21488135 | In-frame |
| ENST00000556147 | 21488078 | 21488135 | In-frame |
| ENST00000298687 | 21488654 | 21488741 | In-frame |
| ENST00000397851 | 21488654 | 21488741 | In-frame |
| ENST00000397853 | 21488654 | 21488741 | In-frame |
| ENST00000397858 | 21488654 | 21488741 | In-frame |
| ENST00000556147 | 21488654 | 21488741 | In-frame |
| ENST00000298687 | 21491022 | 21491064 | In-frame |
| ENST00000397851 | 21491022 | 21491064 | In-frame |
| ENST00000397853 | 21491022 | 21491064 | In-frame |
| ENST00000397858 | 21491022 | 21491064 | In-frame |
| ENST00000556147 | 21491022 | 21491064 | In-frame |
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Infer the effects of exon skipping event on protein functional features for NDRG2 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000298687 | 2139 | 371 | 21491022 | 21491064 | 249 | 290 | 25 | 39 |
| ENST00000397851 | 2039 | 371 | 21491022 | 21491064 | 159 | 200 | 25 | 39 |
| ENST00000397853 | 2096 | 371 | 21491022 | 21491064 | 215 | 256 | 25 | 39 |
| ENST00000397858 | 2071 | 371 | 21491022 | 21491064 | 182 | 223 | 25 | 39 |
| ENST00000556147 | 2897 | 371 | 21491022 | 21491064 | 1017 | 1058 | 25 | 39 |
| ENST00000298687 | 2139 | 371 | 21488654 | 21488741 | 642 | 728 | 156 | 185 |
| ENST00000397851 | 2039 | 371 | 21488654 | 21488741 | 552 | 638 | 156 | 185 |
| ENST00000397853 | 2096 | 371 | 21488654 | 21488741 | 608 | 694 | 156 | 185 |
| ENST00000397858 | 2071 | 371 | 21488654 | 21488741 | 575 | 661 | 156 | 185 |
| ENST00000556147 | 2897 | 371 | 21488654 | 21488741 | 1410 | 1496 | 156 | 185 |
| ENST00000298687 | 2139 | 371 | 21488078 | 21488135 | 729 | 785 | 185 | 204 |
| ENST00000397851 | 2039 | 371 | 21488078 | 21488135 | 639 | 695 | 185 | 204 |
| ENST00000397853 | 2096 | 371 | 21488078 | 21488135 | 695 | 751 | 185 | 204 |
| ENST00000397858 | 2071 | 371 | 21488078 | 21488135 | 662 | 718 | 185 | 204 |
| ENST00000556147 | 2897 | 371 | 21488078 | 21488135 | 1497 | 1553 | 185 | 204 |
| ENST00000298687 | 2139 | 371 | 21486615 | 21486663 | 987 | 1034 | 271 | 287 |
| ENST00000397851 | 2039 | 371 | 21486615 | 21486663 | 897 | 944 | 271 | 287 |
| ENST00000397853 | 2096 | 371 | 21486615 | 21486663 | 953 | 1000 | 271 | 287 |
| ENST00000397858 | 2071 | 371 | 21486615 | 21486663 | 920 | 967 | 271 | 287 |
| ENST00000556147 | 2897 | 371 | 21486615 | 21486663 | 1755 | 1802 | 271 | 287 |
| ENST00000298687 | 2139 | 371 | 21486362 | 21486398 | 1035 | 1070 | 287 | 299 |
| ENST00000397851 | 2039 | 371 | 21486362 | 21486398 | 945 | 980 | 287 | 299 |
| ENST00000397853 | 2096 | 371 | 21486362 | 21486398 | 1001 | 1036 | 287 | 299 |
| ENST00000397858 | 2071 | 371 | 21486362 | 21486398 | 968 | 1003 | 287 | 299 |
| ENST00000556147 | 2897 | 371 | 21486362 | 21486398 | 1803 | 1838 | 287 | 299 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000298687 | 2139 | 371 | 21491022 | 21491064 | 249 | 290 | 25 | 39 |
| ENST00000397851 | 2039 | 371 | 21491022 | 21491064 | 159 | 200 | 25 | 39 |
| ENST00000397853 | 2096 | 371 | 21491022 | 21491064 | 215 | 256 | 25 | 39 |
| ENST00000397858 | 2071 | 371 | 21491022 | 21491064 | 182 | 223 | 25 | 39 |
| ENST00000556147 | 2897 | 371 | 21491022 | 21491064 | 1017 | 1058 | 25 | 39 |
| ENST00000298687 | 2139 | 371 | 21488654 | 21488741 | 642 | 728 | 156 | 185 |
| ENST00000397851 | 2039 | 371 | 21488654 | 21488741 | 552 | 638 | 156 | 185 |
| ENST00000397853 | 2096 | 371 | 21488654 | 21488741 | 608 | 694 | 156 | 185 |
| ENST00000397858 | 2071 | 371 | 21488654 | 21488741 | 575 | 661 | 156 | 185 |
| ENST00000556147 | 2897 | 371 | 21488654 | 21488741 | 1410 | 1496 | 156 | 185 |
| ENST00000298687 | 2139 | 371 | 21488078 | 21488135 | 729 | 785 | 185 | 204 |
| ENST00000397851 | 2039 | 371 | 21488078 | 21488135 | 639 | 695 | 185 | 204 |
| ENST00000397853 | 2096 | 371 | 21488078 | 21488135 | 695 | 751 | 185 | 204 |
| ENST00000397858 | 2071 | 371 | 21488078 | 21488135 | 662 | 718 | 185 | 204 |
| ENST00000556147 | 2897 | 371 | 21488078 | 21488135 | 1497 | 1553 | 185 | 204 |
| ENST00000298687 | 2139 | 371 | 21486615 | 21486663 | 987 | 1034 | 271 | 287 |
| ENST00000397851 | 2039 | 371 | 21486615 | 21486663 | 897 | 944 | 271 | 287 |
| ENST00000397853 | 2096 | 371 | 21486615 | 21486663 | 953 | 1000 | 271 | 287 |
| ENST00000397858 | 2071 | 371 | 21486615 | 21486663 | 920 | 967 | 271 | 287 |
| ENST00000556147 | 2897 | 371 | 21486615 | 21486663 | 1755 | 1802 | 271 | 287 |
| ENST00000298687 | 2139 | 371 | 21486362 | 21486398 | 1035 | 1070 | 287 | 299 |
| ENST00000397851 | 2039 | 371 | 21486362 | 21486398 | 945 | 980 | 287 | 299 |
| ENST00000397853 | 2096 | 371 | 21486362 | 21486398 | 1001 | 1036 | 287 | 299 |
| ENST00000397858 | 2071 | 371 | 21486362 | 21486398 | 968 | 1003 | 287 | 299 |
| ENST00000556147 | 2897 | 371 | 21486362 | 21486398 | 1803 | 1838 | 287 | 299 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for NDRG2 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| ESCA | TCGA-L5-A8NW-01 | exon_skip_111047 | 21488079 | 21488135 | 21488086 | 21488086 | Frame_Shift_Del | A | - | p.F202fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_111047 | 21488079 | 21488135 | 21488097 | 21488097 | Frame_Shift_Del | A | - | p.L198fs |
| BLCA | TCGA-GC-A3WC-01 | exon_skip_111032 | 21486616 | 21486663 | 21486650 | 21486650 | Nonsense_Mutation | G | C | p.S276* |
| COAD | TCGA-G4-6588-01 | 21491400 | 21491480 | 21491453 | 21491453 | Nonsense_Mutation | G | A | p.Q8X |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| 22RV1_PROSTATE | 21490551 | 21490656 | 21490600 | 21490600 | Frame_Shift_Del | G | - | p.P58fs |
| KPNYS_AUTONOMIC_GANGLIA | 21486363 | 21486398 | 21486378 | 21486378 | Missense_Mutation | C | A | p.Q294H |
| SNU175_LARGE_INTESTINE | 21486616 | 21486663 | 21486618 | 21486618 | Missense_Mutation | T | C | p.K287E |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 21486616 | 21486663 | 21486638 | 21486638 | Missense_Mutation | G | T | p.P280H |
| KATOIII_STOMACH | 21488079 | 21488135 | 21488099 | 21488099 | Missense_Mutation | G | A | p.L198F |
| JHUEM1_ENDOMETRIUM | 21488655 | 21488741 | 21488662 | 21488662 | Missense_Mutation | G | A | p.A183V |
| UACC62_SKIN | 21488655 | 21488741 | 21488731 | 21488731 | Missense_Mutation | G | A | p.P160L |
| MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 21491400 | 21491480 | 21491453 | 21491453 | Nonsense_Mutation | G | A | p.Q8* |
| MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 21491400 | 21491480 | 21491453 | 21491453 | Nonsense_Mutation | G | A | p.Q8* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for NDRG2 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for NDRG2 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for NDRG2 |
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RelatedDrugs for NDRG2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NDRG2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| NDRG2 | C0007787 | Transient Ischemic Attack | 1 | CTD_human |
| NDRG2 | C0009375 | Colonic Neoplasms | 1 | CTD_human |
| NDRG2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| NDRG2 | C0086543 | Cataract | 1 | CTD_human |
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