ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for CD36

Gene summary

Gene information	Gene symbol	CD36
	Gene ID	948
	Gene name	CD36 molecule
	Synonyms	BDPLT10\|CHDS7\|FAT\|GP3B\|GP4\|GPIV\|PASIV\|SCARB3
	Cytomap	7q21.11
	Type of gene	protein-coding
	Description	platelet glycoprotein 4CD36 antigen (collagen type I receptor, thrombospondin receptor)CD36 molecule (thrombospondin receptor)GPIIIBPAS IVPAS-4 proteincluster determinant 36fatty acid translocaseglycoprotein IIIbleukocyte differentiation antigen
	Modification date	20180520
	UniProtAcc	P16671
	Context	PubMed: CD36 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CD36	GO:0001954	positive regulation of cell-matrix adhesion	17416590
CD36	GO:0007263	nitric oxide mediated signal transduction	17416590
CD36	GO:0019934	cGMP-mediated signaling	17416590
CD36	GO:0044539	long-chain fatty acid import	17416590\|22022213
CD36	GO:0071726	cellular response to diacyl bacterial lipopeptide	16880211

Top

Exon skipping events across known transcript of Ensembl for CD36 from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Top

Gene isoform structures and expression levels for CD36

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

Top

Exon skipping events with PSIs in TCGA for CD36

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_467716	7	80117001:80117097:80175506:80175583:80275403:80275497	80175506:80175583	ENSG00000135218.13	ENST00000435819.1
exon_skip_467736	7	80231540:80231695:80266147:80266319:80275403:80275497	80266147:80266319	ENSG00000135218.13	ENST00000526804.1
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENSG00000135218.13	ENST00000438020.1
exon_skip_467756	7	80267959:80268062:80269159:80269245:80275403:80275497	80269159:80269245	ENSG00000135218.13	ENST00000482059.2
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENSG00000135218.13	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1
exon_skip_467763	7	80290445:80290526:80292305:80292485:80293721:80293813	80292305:80292485	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000447544.2,ENST00000309881.7,ENST00000534394.1,ENST00000544133.1
exon_skip_467768	7	80295758:80295805:80299268:80299338:80300292:80300480	80299268:80299338	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000538969.1,ENST00000447544.2,ENST00000309881.7,ENST00000534394.1
exon_skip_467769	7	80299268:80299338:80300292:80300480:80301237:80301356	80300292:80300480	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000538969.1,ENST00000447544.2,ENST00000309881.7,ENST00000534394.1
exon_skip_467771	7	80300292:80300480:80301237:80301356:80302085:80302159	80301237:80301356	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000538969.1,ENST00000464213.1,ENST00000447544.2,ENST00000309881.7,ENST00000534394.1
exon_skip_467777	7	80301280:80301356:80302085:80302159:80302670:80302725	80302085:80302159	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000538969.1,ENST00000447544.2,ENST00000309881.7,ENST00000534394.1,ENST00000544133.1
exon_skip_467778	7	80302085:80302159:80302670:80302725:80303298:80303435	80302670:80302725	ENSG00000135218.13	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000538969.1,ENST00000447544.2,ENST00000309881.7,ENST00000534394.1,ENST00000544133.1

PSI values of skipped exons in TCGA.

Top

Exon skipping events with PSIs in GTEx for CD36

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_467716	7	80117001:80117097:80175506:80175583:80275403:80275497	80175506:80175583	ENSG00000135218.13	ENST00000435819.1
exon_skip_467736	7	80231540:80231695:80266147:80266319:80275403:80275497	80266147:80266319	ENSG00000135218.13	ENST00000526804.1
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENSG00000135218.13	ENST00000438020.1
exon_skip_467756	7	80267959:80268062:80269159:80269245:80275403:80275497	80269159:80269245	ENSG00000135218.13	ENST00000482059.2
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENSG00000135218.13	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000438020.1,ENST00000394788.3,ENST00000447544.2,ENST00000426978.1,ENST00000432207.1,ENST00000413265.1,ENST00000419819.2,ENST00000538969.1,ENST00000544133.1,ENST00000433696.2
exon_skip_467763	7	80290445:80290526:80292305:80292485:80293721:80293813	80292305:80292485	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000534394.1,ENST00000394788.3,ENST00000447544.2,ENST00000432207.1,ENST00000419819.2,ENST00000544133.1,ENST00000433696.2
exon_skip_467768	7	80295758:80295805:80299268:80299338:80300292:80300480	80299268:80299338	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000534394.1,ENST00000394788.3,ENST00000447544.2,ENST00000432207.1,ENST00000419819.2,ENST00000538969.1
exon_skip_467769	7	80299268:80299338:80300292:80300480:80301237:80301356	80300292:80300480	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000534394.1,ENST00000394788.3,ENST00000447544.2,ENST00000432207.1,ENST00000419819.2,ENST00000538969.1
exon_skip_467771	7	80300292:80300480:80301237:80301356:80302085:80302159	80301237:80301356	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000534394.1,ENST00000394788.3,ENST00000447544.2,ENST00000432207.1,ENST00000419819.2,ENST00000538969.1,ENST00000433696.2,ENST00000464213.1
exon_skip_467777	7	80301280:80301356:80302085:80302159:80302670:80302725	80302085:80302159	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000534394.1,ENST00000394788.3,ENST00000447544.2,ENST00000432207.1,ENST00000419819.2,ENST00000538969.1,ENST00000544133.1,ENST00000433696.2
exon_skip_467778	7	80302085:80302159:80302670:80302725:80303298:80303435	80302670:80302725	ENSG00000135218.13	ENST00000435819.1,ENST00000309881.7,ENST00000534394.1,ENST00000394788.3,ENST00000447544.2,ENST00000432207.1,ENST00000419819.2,ENST00000538969.1,ENST00000544133.1,ENST00000433696.2

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

Top

Open reading frame (ORF) annotation in the exon skipping event for CD36

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000435819	80175506	80175583	5UTR-5UTR
ENST00000394788	80275403	80275497	5UTR-5UTR
ENST00000447544	80275403	80275497	5UTR-5UTR
ENST00000309881	80285855	80286016	Frame-shift
ENST00000394788	80285855	80286016	Frame-shift
ENST00000432207	80285855	80286016	Frame-shift
ENST00000435819	80285855	80286016	Frame-shift
ENST00000447544	80285855	80286016	Frame-shift
ENST00000309881	80299268	80299338	Frame-shift
ENST00000394788	80299268	80299338	Frame-shift
ENST00000432207	80299268	80299338	Frame-shift
ENST00000435819	80299268	80299338	Frame-shift
ENST00000447544	80299268	80299338	Frame-shift
ENST00000309881	80300292	80300480	Frame-shift
ENST00000394788	80300292	80300480	Frame-shift
ENST00000432207	80300292	80300480	Frame-shift
ENST00000435819	80300292	80300480	Frame-shift
ENST00000447544	80300292	80300480	Frame-shift
ENST00000309881	80301237	80301356	Frame-shift
ENST00000394788	80301237	80301356	Frame-shift
ENST00000432207	80301237	80301356	Frame-shift
ENST00000435819	80301237	80301356	Frame-shift
ENST00000447544	80301237	80301356	Frame-shift
ENST00000309881	80302085	80302159	Frame-shift
ENST00000394788	80302085	80302159	Frame-shift
ENST00000432207	80302085	80302159	Frame-shift
ENST00000435819	80302085	80302159	Frame-shift
ENST00000447544	80302085	80302159	Frame-shift
ENST00000309881	80302670	80302725	Frame-shift
ENST00000394788	80302670	80302725	Frame-shift
ENST00000432207	80302670	80302725	Frame-shift
ENST00000435819	80302670	80302725	Frame-shift
ENST00000447544	80302670	80302725	Frame-shift
ENST00000309881	80292305	80292485	In-frame
ENST00000394788	80292305	80292485	In-frame
ENST00000432207	80292305	80292485	In-frame
ENST00000435819	80292305	80292485	In-frame
ENST00000447544	80292305	80292485	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000435819	80175506	80175583	5UTR-5UTR
ENST00000394788	80275403	80275497	5UTR-5UTR
ENST00000447544	80275403	80275497	5UTR-5UTR
ENST00000309881	80285855	80286016	Frame-shift
ENST00000394788	80285855	80286016	Frame-shift
ENST00000432207	80285855	80286016	Frame-shift
ENST00000435819	80285855	80286016	Frame-shift
ENST00000447544	80285855	80286016	Frame-shift
ENST00000309881	80299268	80299338	Frame-shift
ENST00000394788	80299268	80299338	Frame-shift
ENST00000432207	80299268	80299338	Frame-shift
ENST00000435819	80299268	80299338	Frame-shift
ENST00000447544	80299268	80299338	Frame-shift
ENST00000309881	80300292	80300480	Frame-shift
ENST00000394788	80300292	80300480	Frame-shift
ENST00000432207	80300292	80300480	Frame-shift
ENST00000435819	80300292	80300480	Frame-shift
ENST00000447544	80300292	80300480	Frame-shift
ENST00000309881	80301237	80301356	Frame-shift
ENST00000394788	80301237	80301356	Frame-shift
ENST00000432207	80301237	80301356	Frame-shift
ENST00000435819	80301237	80301356	Frame-shift
ENST00000447544	80301237	80301356	Frame-shift
ENST00000309881	80302085	80302159	Frame-shift
ENST00000394788	80302085	80302159	Frame-shift
ENST00000432207	80302085	80302159	Frame-shift
ENST00000435819	80302085	80302159	Frame-shift
ENST00000447544	80302085	80302159	Frame-shift
ENST00000309881	80302670	80302725	Frame-shift
ENST00000394788	80302670	80302725	Frame-shift
ENST00000432207	80302670	80302725	Frame-shift
ENST00000435819	80302670	80302725	Frame-shift
ENST00000447544	80302670	80302725	Frame-shift
ENST00000309881	80292305	80292485	In-frame
ENST00000394788	80292305	80292485	In-frame
ENST00000432207	80292305	80292485	In-frame
ENST00000435819	80292305	80292485	In-frame
ENST00000447544	80292305	80292485	In-frame

Top

Infer the effects of exon skipping event on protein functional features for CD36

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000309881	2111	472	80292305	80292485	843	1022	143	203
ENST00000394788	1959	472	80292305	80292485	684	863	143	203
ENST00000432207	1825	472	80292305	80292485	550	729	143	203
ENST00000435819	2382	472	80292305	80292485	1114	1293	143	203
ENST00000447544	2315	472	80292305	80292485	684	863	143	203

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000309881	2111	472	80292305	80292485	843	1022	143	203
ENST00000394788	1959	472	80292305	80292485	684	863	143	203
ENST00000432207	1825	472	80292305	80292485	550	729	143	203
ENST00000435819	2382	472	80292305	80292485	1114	1293	143	203
ENST00000447544	2315	472	80292305	80292485	684	863	143	203

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.

Start of exon skipping (AA)

End of exon skipping (AA)

Protein feature start (AA)

Protein feature end (AA)

Category of protein feature

Description of feature

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.

Start of exon skipping (AA)

End of exon skipping (AA)

Protein feature start (AA)

Protein feature end (AA)

Category of protein feature

Description of feature

Top

SNVs in the skipped exons for CD36

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
LIHC	TCGA-DD-A39Y-01	exon_skip_467760	80285856	80286016	80285889	80285889	Frame_Shift_Del	A	-	p.K52fs
LIHC	TCGA-DD-A39Y-01	exon_skip_467763	80292306	80292485	80292432	80292432	Frame_Shift_Del	T	-	p.F186fs
LIHC	TCGA-DD-A3A0-01	exon_skip_467763	80292306	80292485	80292432	80292432	Frame_Shift_Del	T	-	p.F186fs
LIHC	TCGA-G3-A3CJ-01	exon_skip_467777	80302086	80302159	80302150	80302150	Frame_Shift_Del	A	-	p.E397fs
UCEC	TCGA-BG-A0VX-01	exon_skip_467777	80302086	80302159	80302149	80302150	Frame_Shift_Ins	-	A	p.E397fs
DLBC	TCGA-G8-6324-01	exon_skip_467769	80300293	80300480	80300449	80300449	Nonsense_Mutation	T	G	p.Y325X
KIRP	TCGA-HE-A5NJ-01	exon_skip_467777	80302086	80302159	80302113	80302113	Nonsense_Mutation	A	T	p.K385*
THYM	TCGA-X7-A8DE-01	exon_skip_467763	80292306	80292485	80292304	80292304	Splice_Site	A	T	.

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons

Mutation description

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
SNU1040_LARGE_INTESTINE	80300293	80300480	80300431	80300431	Frame_Shift_Del	A	-	p.S319fs
CW2_LARGE_INTESTINE	80285856	80286016	80285892	80285892	Missense_Mutation	A	C	p.N53H
RKO_LARGE_INTESTINE	80285856	80286016	80285969	80285969	Missense_Mutation	G	T	p.M78I
NCIH2342_LUNG	80285856	80286016	80285995	80285995	Missense_Mutation	A	G	p.Q87R
MM386_SKIN	80292306	80292485	80292447	80292447	Missense_Mutation	C	T	p.P191S
SW1573_LUNG	80292306	80292485	80292477	80292477	Missense_Mutation	T	C	p.F201L
MYLA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	80299269	80299338	80299274	80299274	Missense_Mutation	G	A	p.A252T
NCIH2135_LUNG	80299269	80299338	80299283	80299283	Missense_Mutation	C	T	p.P255S
DOTC24510_CERVIX	80299269	80299338	80299318	80299318	Missense_Mutation	C	A	p.F266L
HS600T_FIBROBLAST	80301238	80301356	80301305	80301305	Missense_Mutation	T	A	p.D358E
VMRCLCD_LUNG	80301238	80301356	80301305	80301305	Missense_Mutation	T	G	p.D358E
SCC3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	80301238	80301356	80301314	80301314	Missense_Mutation	C	A	p.N361K
NCIH2126_LUNG	80302086	80302159	80302124	80302124	Missense_Mutation	G	T	p.Q388H
NCIH187_LUNG	80302671	80302725	80302680	80302680	Missense_Mutation	G	C	p.K403N
HT29_LARGE_INTESTINE	80302671	80302725	80302684	80302684	Missense_Mutation	C	G	p.L405V
HUCCT1_BILIARY_TRACT	80302671	80302725	80302708	80302708	Missense_Mutation	A	C	p.I413L
SUDHL5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	80302671	80302725	80302714	80302714	Missense_Mutation	T	C	p.W415R
KS1_CENTRAL_NERVOUS_SYSTEM	80302086	80302159	80302080	80302086	Splice_Site	TTTTAGA	-	p.F376fs

Top

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CD36

sQTL information located at the skipped exons.

Exon skip ID	Chromosome	Three exons	Skippped exon	ENST	Cancer type	SNP id	Location	DNA change (ref/var)	P-value
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	ACC	rs1049654	chr7:80275455	A/C	5.69e-06
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	ACC	rs1049654	chr7:80275455	A/C	5.69e-06
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	GBM	rs1049654	chr7:80275455	A/C	3.18e-07
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	GBM	rs1049654	chr7:80275455	A/C	1.21e-04
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	CESC	rs1049654	chr7:80275455	A/C	4.81e-06
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	CESC	rs1049654	chr7:80275455	A/C	5.99e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	BLCA	rs1049654	chr7:80275455	A/C	5.50e-11
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	BLCA	rs1049654	chr7:80275455	A/C	7.45e-10
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	ESCA	rs1049654	chr7:80275455	A/C	1.21e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	ESCA	rs1049654	chr7:80275455	A/C	8.11e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	HNSC	rs1049654	chr7:80275455	A/C	2.61e-12
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	HNSC	rs1049654	chr7:80275455	A/C	6.16e-11
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	BRCA	rs1049654	chr7:80275455	A/C	1.95e-35
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	BRCA	rs1049654	chr7:80275455	A/C	3.74e-35
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LAML	rs1049654	chr7:80275455	A/C	4.17e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LAML	rs1049654	chr7:80275455	A/C	7.85e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	KIRP	rs1049654	chr7:80275455	A/C	3.93e-06
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	KIRP	rs1049654	chr7:80275455	A/C	5.54e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	KIRC	rs1049654	chr7:80275455	A/C	2.60e-23
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	KIRC	rs1049654	chr7:80275455	A/C	2.60e-23
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LUAD	rs1049654	chr7:80275455	A/C	2.83e-15
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LUAD	rs1049654	chr7:80275455	A/C	2.52e-14
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	MESO	rs1049654	chr7:80275455	A/C	1.90e-04
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	MESO	rs1049654	chr7:80275455	A/C	1.90e-04
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LIHC	rs1049654	chr7:80275455	A/C	2.11e-10
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LIHC	rs1049654	chr7:80275455	A/C	2.11e-10
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LUSC	rs1049654	chr7:80275455	A/C	3.41e-15
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	LUSC	rs1049654	chr7:80275455	A/C	1.11e-13
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	OV	rs1049654	chr7:80275455	A/C	1.34e-06
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	OV	rs1049654	chr7:80275455	A/C	4.03e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	PCPG	rs1049654	chr7:80275455	A/C	5.35e-10
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	PCPG	rs1049654	chr7:80275455	A/C	2.22e-08
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	PAAD	rs1049654	chr7:80275455	A/C	1.57e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	PAAD	rs1049654	chr7:80275455	A/C	1.27e-04
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	PRAD	rs1049654	chr7:80275455	A/C	1.40e-07
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	PRAD	rs1049654	chr7:80275455	A/C	3.63e-07
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	SARC	rs1049654	chr7:80275455	A/C	8.24e-09
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	SARC	rs1049654	chr7:80275455	A/C	8.24e-09
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	TGCT	rs1049654	chr7:80275455	A/C	6.71e-07
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	TGCT	rs1049654	chr7:80275455	A/C	2.41e-05
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	STAD	rs1049654	chr7:80275455	A/C	4.33e-11
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	STAD	rs1049654	chr7:80275455	A/C	4.33e-11
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	THCA	rs1049654	chr7:80275455	A/C	5.22e-22
exon_skip_467746	7	80253398:80253506:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000438020.1	THCA	rs1049654	chr7:80275455	A/C	3.00e-21
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	ACC	rs1049654	chr7:80275455	A/C	5.69e-06
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	ACC	rs1049654	chr7:80275455	A/C	5.69e-06
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	GBM	rs1049654	chr7:80275455	A/C	3.18e-07
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	GBM	rs1049654	chr7:80275455	A/C	1.21e-04
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	CESC	rs1049654	chr7:80275455	A/C	4.81e-06
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	CESC	rs1049654	chr7:80275455	A/C	5.99e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	BLCA	rs1049654	chr7:80275455	A/C	5.50e-11
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	BLCA	rs1049654	chr7:80275455	A/C	7.45e-10
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	ESCA	rs1049654	chr7:80275455	A/C	1.21e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	ESCA	rs1049654	chr7:80275455	A/C	8.11e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	HNSC	rs1049654	chr7:80275455	A/C	2.61e-12
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	HNSC	rs1049654	chr7:80275455	A/C	6.16e-11
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	BRCA	rs1049654	chr7:80275455	A/C	1.95e-35
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	BRCA	rs1049654	chr7:80275455	A/C	3.74e-35
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LAML	rs1049654	chr7:80275455	A/C	4.17e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LAML	rs1049654	chr7:80275455	A/C	7.85e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	KIRP	rs1049654	chr7:80275455	A/C	3.93e-06
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	KIRP	rs1049654	chr7:80275455	A/C	5.54e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	KIRC	rs1049654	chr7:80275455	A/C	2.60e-23
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	KIRC	rs1049654	chr7:80275455	A/C	2.60e-23
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LUAD	rs1049654	chr7:80275455	A/C	2.83e-15
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LUAD	rs1049654	chr7:80275455	A/C	2.52e-14
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	MESO	rs1049654	chr7:80275455	A/C	1.90e-04
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	MESO	rs1049654	chr7:80275455	A/C	1.90e-04
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LIHC	rs1049654	chr7:80275455	A/C	2.11e-10
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LIHC	rs1049654	chr7:80275455	A/C	2.11e-10
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LUSC	rs1049654	chr7:80275455	A/C	3.41e-15
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	LUSC	rs1049654	chr7:80275455	A/C	1.11e-13
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	OV	rs1049654	chr7:80275455	A/C	1.34e-06
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	OV	rs1049654	chr7:80275455	A/C	4.03e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	PCPG	rs1049654	chr7:80275455	A/C	5.35e-10
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	PCPG	rs1049654	chr7:80275455	A/C	2.22e-08
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	PAAD	rs1049654	chr7:80275455	A/C	1.57e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	PAAD	rs1049654	chr7:80275455	A/C	1.27e-04
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	PRAD	rs1049654	chr7:80275455	A/C	1.40e-07
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	PRAD	rs1049654	chr7:80275455	A/C	3.63e-07
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	SARC	rs1049654	chr7:80275455	A/C	8.24e-09
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	SARC	rs1049654	chr7:80275455	A/C	8.24e-09
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	TGCT	rs1049654	chr7:80275455	A/C	6.71e-07
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	TGCT	rs1049654	chr7:80275455	A/C	2.41e-05
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	STAD	rs1049654	chr7:80275455	A/C	4.33e-11
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	STAD	rs1049654	chr7:80275455	A/C	4.33e-11
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	THCA	rs1049654	chr7:80275455	A/C	5.22e-22
exon_skip_467758	7	80267991:80268062:80275403:80275497:80275967:80276042	80275403:80275497	ENST00000441109.2,ENST00000394788.3,ENST00000447544.2	THCA	rs1049654	chr7:80275455	A/C	3.00e-21
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1	BLCA	rs3173798	chr7:80285850	T/C	2.54e-05
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1	BLCA	rs3173798	chr7:80285850	T/C	3.72e-05
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1	KIRC	rs3173798	chr7:80285850	T/C	2.50e-04
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1	KIRC	rs3173798	chr7:80285850	T/C	2.50e-04
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1	LIHC	rs3173798	chr7:80285850	T/C	1.72e-05
exon_skip_467760	7	80276024:80276176:80285855:80286016:80290378:80290526	80285855:80286016	ENST00000419819.2,ENST00000394788.3,ENST00000432207.1,ENST00000435819.1,ENST00000433696.2,ENST00000413265.1,ENST00000538969.1,ENST00000438020.1,ENST00000447544.2,ENST00000309881.7,ENST00000426978.1,ENST00000544133.1	LIHC	rs3173798	chr7:80285850	T/C	1.72e-05

Top

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CD36

Top

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CD36

Top

RelatedDrugs for CD36

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for CD36

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CD36	C0007193	Cardiomyopathy, Dilated	1	CTD_human
CD36	C0020538	Hypertensive disease	1	CTD_human
CD36	C0021051	Immunologic Deficiency Syndromes	1	CTD_human
CD36	C0021655	Insulin Resistance	1	CTD_human
CD36	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
CD36	C0035126	Reperfusion Injury	1	CTD_human
CD36	C0038160	Staphylococcal Infections	1	CTD_human
CD36	C0043094	Weight Gain	1	CTD_human
CD36	C0151744	Myocardial Ischemia	1	CTD_human
CD36	C0162820	Dermatitis, Allergic Contact	1	CTD_human
CD36	C0271650	Impaired glucose tolerance	1	CTD_human
CD36	C1842090	Platelet Glycoprotein IV Deficiency	1	CTD_human;UNIPROT

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

Home

Download

Statistics

Landscape

Help

Contact