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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for ZNF333 |
 Gene summary |
| Gene information | Gene symbol | ZNF333 | Gene ID | 84449 |
| Gene name | zinc finger protein 333 | |
| Synonyms | - | |
| Cytomap | 19p13.12 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 333 | |
| Modification date | 20180523 | |
| UniProtAcc | Q96JL9 | |
| Context | PubMed: ZNF333 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for ZNF333 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for ZNF333 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for ZNF333 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_303048 | 19 | 14800917:14800962:14804262:14804306:14805821:14805945 | 14804262:14804306 | ENSG00000160961.7 | ENST00000596285.1,ENST00000601629.1,ENST00000597301.1,ENST00000601134.1,ENST00000292530.6,ENST00000597007.1,ENST00000540689.2 |
| exon_skip_303050 | 19 | 14804262:14804306:14805821:14805945:14806377:14806473 | 14805821:14805945 | ENSG00000160961.7 | ENST00000596285.1,ENST00000601629.1,ENST00000598161.1,ENST00000597301.1,ENST00000292530.6,ENST00000597007.1,ENST00000540689.2,ENST00000392987.3,ENST00000536363.1 |
| exon_skip_303055 | 19 | 14810010:14810093:14812395:14812709:14815865:14815982 | 14812395:14812709 | ENSG00000160961.7 | ENST00000597007.1,ENST00000536363.1 |
| exon_skip_303061 | 19 | 14817497:14817585:14818728:14818777:14819139:14820032 | 14818728:14818777 | ENSG00000160961.7 | ENST00000601134.1 |
| exon_skip_303064 | 19 | 14826193:14826282:14826923:14827050:14827805:14827901 | 14826923:14827050 | ENSG00000160961.7 | ENST00000598161.1,ENST00000597301.1,ENST00000292530.6,ENST00000540689.2,ENST00000536363.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for ZNF333 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_303048 | 19 | 14800917:14800962:14804262:14804306:14805821:14805945 | 14804262:14804306 | ENSG00000160961.7 | ENST00000597007.1,ENST00000596285.1,ENST00000540689.2,ENST00000601134.1,ENST00000601629.1,ENST00000292530.6,ENST00000597301.1 |
| exon_skip_303050 | 19 | 14804262:14804306:14805821:14805945:14806377:14806473 | 14805821:14805945 | ENSG00000160961.7 | ENST00000392987.3,ENST00000536363.1,ENST00000597007.1,ENST00000596285.1,ENST00000540689.2,ENST00000601629.1,ENST00000292530.6,ENST00000597301.1,ENST00000598161.1 |
| exon_skip_303055 | 19 | 14810010:14810093:14812395:14812709:14815865:14815982 | 14812395:14812709 | ENSG00000160961.7 | ENST00000536363.1,ENST00000597007.1 |
| exon_skip_303061 | 19 | 14817497:14817585:14818728:14818777:14819139:14820032 | 14818728:14818777 | ENSG00000160961.7 | ENST00000601134.1 |
| exon_skip_303064 | 19 | 14826193:14826282:14826923:14827050:14827805:14827901 | 14826923:14827050 | ENSG00000160961.7 | ENST00000536363.1,ENST00000540689.2,ENST00000292530.6,ENST00000597301.1,ENST00000598161.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for ZNF333 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000292530 | 14804262 | 14804306 | 5CDS-5UTR |
| ENST00000292530 | 14805821 | 14805945 | Frame-shift |
| ENST00000292530 | 14826923 | 14827050 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000292530 | 14804262 | 14804306 | 5CDS-5UTR |
| ENST00000292530 | 14805821 | 14805945 | Frame-shift |
| ENST00000292530 | 14826923 | 14827050 | Frame-shift |
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Infer the effects of exon skipping event on protein functional features for ZNF333 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for ZNF333 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LUSC | TCGA-21-5786-01 | exon_skip_303050 | 14805822 | 14805945 | 14805852 | 14805852 | Nonsense_Mutation | G | T | p.E12* |
| HNSC | TCGA-CV-7434-01 | exon_skip_303050 | 14805822 | 14805945 | 14805946 | 14805946 | Splice_Site | G | A | p.G43_splice |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SNU719_STOMACH | 14826924 | 14827050 | 14826960 | 14826960 | Missense_Mutation | A | G | p.T213A |
| KMS18_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 14826924 | 14827050 | 14826963 | 14826963 | Missense_Mutation | C | G | p.P214A |
| SNU1040_LARGE_INTESTINE | 14826924 | 14827050 | 14827019 | 14827019 | Missense_Mutation | G | A | p.M232I |
| JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 14826924 | 14827050 | 14827047 | 14827047 | Missense_Mutation | G | A | p.V242M |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNF333 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF333 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF333 |
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RelatedDrugs for ZNF333 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF333 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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