|
||||||
|
 | |
| |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
| |
|
Gene summary for KCTD10 |
 Gene summary |
| Gene information | Gene symbol | KCTD10 | Gene ID | 83892 |
| Gene name | potassium channel tetramerization domain containing 10 | |
| Synonyms | BTBD28|MSTP028|ULRO61|hBACURD3 | |
| Cytomap | 12q24.11 | |
| Type of gene | protein-coding | |
| Description | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3BTB/POZ domain-containing protein KCTD10potassium channel tetramerisation domain containing 10potassium channel tetramerization domain-containing protein 10 | |
| Modification date | 20180519 | |
| UniProtAcc | Q9H3F6 | |
| Context | PubMed: KCTD10 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| KCTD10 | GO:0006511 | ubiquitin-dependent protein catabolic process | 25401743 |
Top |
Exon skipping events across known transcript of Ensembl for KCTD10 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Gene isoform structures and expression levels for KCTD10 |
| Expression levels of gene isoforms across TCGA. |
 |
| Expression levels of gene isoforms across GTEx. |
 |
Top |
Exon skipping events with PSIs in TCGA for KCTD10 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_96030 | 12 | 109895434:109895487:109895796:109895853:109898440:109898610 | 109895796:109895853 | ENSG00000110906.8 | ENST00000542858.1 |
| exon_skip_96031 | 12 | 109895434:109895487:109895796:109895883:109898440:109898610 | 109895796:109895883 | ENSG00000110906.8 | ENST00000538161.1,ENST00000540411.1,ENST00000228495.6 |
| exon_skip_96032 | 12 | 109895434:109895487:109895796:109895886:109898440:109898610 | 109895796:109895886 | ENSG00000110906.8 | ENST00000537165.1 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENSG00000110906.8 | ENST00000541077.1 |
| exon_skip_96036 | 12 | 109895796:109895883:109898440:109898610:109907319:109907529 | 109898440:109898610 | ENSG00000110906.8 | ENST00000540411.1,ENST00000228495.6 |
| exon_skip_96037 | 12 | 109895796:109895886:109898440:109898610:109907319:109907529 | 109898440:109898610 | ENSG00000110906.8 | ENST00000537165.1 |
| exon_skip_96040 | 12 | 109898440:109898610:109907319:109907533:109915064:109915094 | 109907319:109907533 | ENSG00000110906.8 | ENST00000542262.1,ENST00000542858.1,ENST00000535747.1 |
| PSI values of skipped exons in TCGA. |
 |
Top |
Exon skipping events with PSIs in GTEx for KCTD10 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_96030 | 12 | 109895434:109895487:109895796:109895853:109898440:109898610 | 109895796:109895853 | ENSG00000110906.8 | ENST00000542858.1 |
| exon_skip_96031 | 12 | 109895434:109895487:109895796:109895883:109898440:109898610 | 109895796:109895883 | ENSG00000110906.8 | ENST00000228495.6,ENST00000538161.1,ENST00000540411.1 |
| exon_skip_96032 | 12 | 109895434:109895487:109895796:109895886:109898440:109898610 | 109895796:109895886 | ENSG00000110906.8 | ENST00000537165.1 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENSG00000110906.8 | ENST00000541077.1 |
| exon_skip_96036 | 12 | 109895796:109895883:109898440:109898610:109907319:109907529 | 109898440:109898610 | ENSG00000110906.8 | ENST00000228495.6,ENST00000540411.1 |
| exon_skip_96037 | 12 | 109895796:109895886:109898440:109898610:109907319:109907529 | 109898440:109898610 | ENSG00000110906.8 | ENST00000537165.1 |
| exon_skip_96040 | 12 | 109898440:109898610:109907319:109907533:109915064:109915094 | 109907319:109907533 | ENSG00000110906.8 | ENST00000542262.1,ENST00000542858.1,ENST00000535747.1 |
| exon_skip_96041 | 12 | 109898440:109898610:109907319:109909182:109915064:109915094 | 109907319:109909182 | ENSG00000110906.8 | ENST00000537165.1 |
| PSI values of skipped exons in GTEx. |
 |
| * Skipped exon sequences. |
Top |
Open reading frame (ORF) annotation in the exon skipping event for KCTD10 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000228495 | 109898440 | 109898610 | Frame-shift |
| ENST00000228495 | 109895796 | 109895883 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000228495 | 109898440 | 109898610 | Frame-shift |
| ENST00000228495 | 109895796 | 109895883 | In-frame |
Top |
Infer the effects of exon skipping event on protein functional features for KCTD10 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
 |
| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000228495 | 4180 | 313 | 109895796 | 109895883 | 670 | 756 | 129 | 158 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000228495 | 4180 | 313 | 109895796 | 109895883 | 670 | 756 | 129 | 158 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9H3F6 | 129 | 158 | 1 | 158 | Alternative sequence | ID=VSP_019978;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.5 |
| Q9H3F6 | 129 | 158 | 1 | 313 | Chain | ID=PRO_0000247421;Note=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9H3F6 | 129 | 158 | 1 | 158 | Alternative sequence | ID=VSP_019978;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.5 |
| Q9H3F6 | 129 | 158 | 1 | 313 | Chain | ID=PRO_0000247421;Note=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 |
Top |
SNVs in the skipped exons for KCTD10 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
 |
| - Differential PSIs between mutated versus non-mutated samples. |
KCTD10_STAD_exon_skip_96034_psi_boxplot.png |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SARC | TCGA-3R-A8YX-01 | exon_skip_96030 | 109895797 | 109895853 | 109895815 | 109895816 | Frame_Shift_Del | AA | - | p.L152fs |
| SARC | TCGA-3R-A8YX-01 | exon_skip_96031 | 109895797 | 109895883 | 109895815 | 109895816 | Frame_Shift_Del | AA | - | p.L152fs |
| SARC | TCGA-3R-A8YX-01 | exon_skip_96032 | 109895797 | 109895886 | 109895815 | 109895816 | Frame_Shift_Del | AA | - | p.L152fs |
| SARC | TCGA-3R-A8YX-01 | exon_skip_96034 | 109895797 | 109895989 | 109895815 | 109895816 | Frame_Shift_Del | AA | - | p.L152fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_96040 | 109907320 | 109907533 | 109907450 | 109907450 | Frame_Shift_Del | G | - | p.P29fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_96040 | 109907320 | 109907533 | 109907479 | 109907479 | Frame_Shift_Del | G | - | p.R20fs |
| STAD | TCGA-CG-5721-01 | exon_skip_96040 | 109907320 | 109907533 | 109907347 | 109907348 | Frame_Shift_Ins | - | C | p.R64fs |
| STAD | TCGA-CG-5721-01 | exon_skip_96040 | 109907320 | 109907533 | 109907348 | 109907349 | Frame_Shift_Ins | - | C | p.G71fs |
| COAD | TCGA-AA-3510-01 | exon_skip_96030 | 109895797 | 109895853 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S156X |
| COAD | TCGA-AA-3510-01 | exon_skip_96031 | 109895797 | 109895883 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S156X |
| COAD | TCGA-AA-3510-01 | exon_skip_96032 | 109895797 | 109895886 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S156X |
| COAD | TCGA-AA-3510-01 | exon_skip_96034 | 109895797 | 109895989 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S156X |
| LUSC | TCGA-22-1011-01 | exon_skip_96030 | 109895797 | 109895853 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S165* |
| LUSC | TCGA-22-1011-01 | exon_skip_96031 | 109895797 | 109895883 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S165* |
| LUSC | TCGA-22-1011-01 | exon_skip_96032 | 109895797 | 109895886 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S165* |
| LUSC | TCGA-22-1011-01 | exon_skip_96034 | 109895797 | 109895989 | 109895804 | 109895804 | Nonsense_Mutation | G | T | p.S165* |
| STAD | TCGA-HU-8602-01 | exon_skip_96030 | 109895797 | 109895853 | 109895795 | 109895795 | Splice_Site | A | G | . |
| STAD | TCGA-HU-8602-01 | exon_skip_96030 | 109895797 | 109895853 | 109895795 | 109895795 | Splice_Site | A | G | p.K158_splice |
| STAD | TCGA-HU-8602-01 | exon_skip_96031 | 109895797 | 109895883 | 109895795 | 109895795 | Splice_Site | A | G | . |
| STAD | TCGA-HU-8602-01 | exon_skip_96031 | 109895797 | 109895883 | 109895795 | 109895795 | Splice_Site | A | G | p.K158_splice |
| STAD | TCGA-HU-8602-01 | exon_skip_96032 | 109895797 | 109895886 | 109895795 | 109895795 | Splice_Site | A | G | . |
| STAD | TCGA-HU-8602-01 | exon_skip_96032 | 109895797 | 109895886 | 109895795 | 109895795 | Splice_Site | A | G | p.K158_splice |
| STAD | TCGA-HU-8602-01 | exon_skip_96034 | 109895797 | 109895989 | 109895795 | 109895795 | Splice_Site | A | G | . |
| STAD | TCGA-HU-8602-01 | exon_skip_96034 | 109895797 | 109895989 | 109895795 | 109895795 | Splice_Site | A | G | p.K158_splice |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96032 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895886 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: . | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96030 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895853 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: . | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96031 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895883 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: . | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96034 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895989 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: . | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96032 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895886 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: p.K158_splice | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96030 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895853 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: p.K158_splice | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96031 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895883 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: p.K158_splice | |
| Sample: TCGA-HU-8602-01 |
| Cancer type: STAD | |
| ESID: exon_skip_96034 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895989 | |
| Mutation start: 109895795 | |
| Mutation end: 109895795 | |
| Mutation type: Splice_Site | |
| Reference seq: A | |
| Mutation seq: G | |
| AAchange: p.K158_splice | |
exon_skip_110606_STAD_TCGA-HU-8602-01.png | |
exon_skip_12723_STAD_TCGA-HU-8602-01.png | |
exon_skip_12741_STAD_TCGA-HU-8602-01.png | |
exon_skip_129202_STAD_TCGA-HU-8602-01.png | |
exon_skip_142361_STAD_TCGA-HU-8602-01.png | |
exon_skip_17013_STAD_TCGA-HU-8602-01.png | |
exon_skip_28391_STAD_TCGA-HU-8602-01.png | |
exon_skip_328529_STAD_TCGA-HU-8602-01.png | |
exon_skip_35193_STAD_TCGA-HU-8602-01.png | |
exon_skip_364609_STAD_TCGA-HU-8602-01.png | |
exon_skip_3733_STAD_TCGA-HU-8602-01.png | |
exon_skip_3734_STAD_TCGA-HU-8602-01.png | |
exon_skip_424540_STAD_TCGA-HU-8602-01.png | |
exon_skip_443675_STAD_TCGA-HU-8602-01.png | |
exon_skip_466134_STAD_TCGA-HU-8602-01.png | |
exon_skip_475115_STAD_TCGA-HU-8602-01.png | |
exon_skip_482067_STAD_TCGA-HU-8602-01.png | |
exon_skip_489785_STAD_TCGA-HU-8602-01.png | |
exon_skip_489794_STAD_TCGA-HU-8602-01.png | |
exon_skip_493826_STAD_TCGA-HU-8602-01.png | |
exon_skip_493827_STAD_TCGA-HU-8602-01.png | |
exon_skip_51385_STAD_TCGA-HU-8602-01.png | |
exon_skip_81726_STAD_TCGA-HU-8602-01.png | |
exon_skip_84502_STAD_TCGA-HU-8602-01.png | |
exon_skip_96034_STAD_TCGA-HU-8602-01.png | |
 | Sample: TCGA-22-1011-01 |
| Cancer type: LUSC | |
| ESID: exon_skip_96032 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895886 | |
| Mutation start: 109895804 | |
| Mutation end: 109895804 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: T | |
| AAchange: p.S165* | |
| Sample: TCGA-22-1011-01 |
| Cancer type: LUSC | |
| ESID: exon_skip_96030 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895853 | |
| Mutation start: 109895804 | |
| Mutation end: 109895804 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: T | |
| AAchange: p.S165* | |
| Sample: TCGA-22-1011-01 |
| Cancer type: LUSC | |
| ESID: exon_skip_96031 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895883 | |
| Mutation start: 109895804 | |
| Mutation end: 109895804 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: T | |
| AAchange: p.S165* | |
| Sample: TCGA-22-1011-01 |
| Cancer type: LUSC | |
| ESID: exon_skip_96034 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895989 | |
| Mutation start: 109895804 | |
| Mutation end: 109895804 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: T | |
| AAchange: p.S165* | |
exon_skip_96034_LUSC_TCGA-22-1011-01.png | |
 | Sample: TCGA-3R-A8YX-01 |
| Cancer type: SARC | |
| ESID: exon_skip_96032 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895886 | |
| Mutation start: 109895815 | |
| Mutation end: 109895816 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: AA | |
| Mutation seq: - | |
| AAchange: p.L152fs | |
| Sample: TCGA-3R-A8YX-01 |
| Cancer type: SARC | |
| ESID: exon_skip_96030 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895853 | |
| Mutation start: 109895815 | |
| Mutation end: 109895816 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: AA | |
| Mutation seq: - | |
| AAchange: p.L152fs | |
| Sample: TCGA-3R-A8YX-01 |
| Cancer type: SARC | |
| ESID: exon_skip_96031 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895883 | |
| Mutation start: 109895815 | |
| Mutation end: 109895816 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: AA | |
| Mutation seq: - | |
| AAchange: p.L152fs | |
| Sample: TCGA-3R-A8YX-01 |
| Cancer type: SARC | |
| ESID: exon_skip_96034 | |
| Skipped exon start: 109895797 | |
| Skipped exon end: 109895989 | |
| Mutation start: 109895815 | |
| Mutation end: 109895816 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: AA | |
| Mutation seq: - | |
| AAchange: p.L152fs | |
exon_skip_96034_SARC_TCGA-3R-A8YX-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 109898441 | 109898610 | 109898543 | 109898544 | Frame_Shift_Del | CG | - | p.A95fs |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 109898441 | 109898610 | 109898539 | 109898540 | Frame_Shift_Ins | - | TA | p.P97fs |
| AN3CA_ENDOMETRIUM | 109895797 | 109895886 | 109895870 | 109895870 | Missense_Mutation | T | C | p.Y134C |
| AN3CA_ENDOMETRIUM | 109895797 | 109895883 | 109895870 | 109895870 | Missense_Mutation | T | C | p.Y134C |
| AN3CA_ENDOMETRIUM | 109895797 | 109895989 | 109895870 | 109895870 | Missense_Mutation | T | C | p.Y134C |
| HEC6_ENDOMETRIUM | 109895797 | 109895886 | 109895875 | 109895875 | Missense_Mutation | A | T | p.D132E |
| HEC6_ENDOMETRIUM | 109895797 | 109895883 | 109895875 | 109895875 | Missense_Mutation | A | T | p.D132E |
| HEC6_ENDOMETRIUM | 109895797 | 109895989 | 109895875 | 109895875 | Missense_Mutation | A | T | p.D132E |
| HEKTE_KIDNEY | 109898441 | 109898610 | 109898520 | 109898520 | Missense_Mutation | C | T | p.R103Q |
| EFO27_OVARY | 109898441 | 109898610 | 109898521 | 109898521 | Missense_Mutation | G | A | p.R103W |
| MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 109898441 | 109898610 | 109898544 | 109898544 | Missense_Mutation | G | A | p.A95V |
| SARC9371_BONE | 109898441 | 109898610 | 109898557 | 109898557 | Missense_Mutation | G | A | p.L91F |
| 639V_URINARY_TRACT | 109907320 | 109907533 | 109907346 | 109907346 | Missense_Mutation | C | T | p.R64H |
| HEC151_ENDOMETRIUM | 109907320 | 109907533 | 109907347 | 109907347 | Missense_Mutation | G | A | p.R64C |
| DOK_UPPER_AERODIGESTIVE_TRACT | 109907320 | 109907533 | 109907505 | 109907505 | Missense_Mutation | C | A | p.S11I |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 109907320 | 109907533 | 109907516 | 109907516 | Missense_Mutation | T | G | p.E7D |
| ML1_THYROID | 109907320 | 109907533 | 109907533 | 109907533 | Splice_Site | C | T | p.E2K |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for KCTD10 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | ESCA | rs11609019 | chr12:109895958 | G/A | 1.07e-18 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | ESCA | rs11609019 | chr12:109895958 | G/A | 2.02e-04 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | HNSC | rs11609019 | chr12:109895958 | G/A | 3.71e-33 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | BRCA | rs11609019 | chr12:109895958 | G/A | 2.40e-39 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | BRCA | rs11609019 | chr12:109895958 | G/A | 8.62e-04 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | LGG | rs11609019 | chr12:109895958 | G/A | 8.54e-15 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | KIRC | rs11609019 | chr12:109895958 | G/A | 8.84e-43 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | KIRC | rs11609019 | chr12:109895958 | G/A | 1.53e-03 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | LUAD | rs11609019 | chr12:109895958 | G/A | 1.84e-24 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | MESO | rs11609019 | chr12:109895958 | G/A | 2.00e-07 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | LUSC | rs11609019 | chr12:109895958 | G/A | 3.20e-41 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | OV | rs11609019 | chr12:109895958 | G/A | 3.91e-11 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | READ | rs11609019 | chr12:109895958 | G/A | 1.23e-09 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | PAAD | rs11609019 | chr12:109895958 | G/A | 2.36e-15 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | PRAD | rs11609019 | chr12:109895958 | G/A | 5.07e-12 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | SARC | rs11609019 | chr12:109895958 | G/A | 6.52e-12 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | SKCM | rs11609019 | chr12:109895958 | G/A | 1.38e-05 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | STAD | rs11609019 | chr12:109895958 | G/A | 4.23e-08 |
| exon_skip_96034 | 12 | 109895434:109895487:109895796:109895989:109898440:109898610 | 109895796:109895989 | ENST00000541077.1 | THCA | rs11609019 | chr12:109895958 | G/A | 9.49e-20 |
Top |
Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for KCTD10 |
Top |
Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for KCTD10 |
Top |
RelatedDrugs for KCTD10 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for KCTD10 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|