ExonSkipDB Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
leaf

Gene summary

leaf

Gene structures and expression levels

leaf

Exon skipping events with PSIs in TCGA

leaf

Exon skipping events with PSIs in GTEx

leaf

Open reading frame (ORF) annotation in the exon skipping event

leaf

Exon skipping events in the canonical protein sequence

leaf

SNVs in the skipped exons with depth of coverage

leaf

Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

leaf

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

leaf

Related drugs with this gene

leaf

Related diseases with this gene

Gene summary for FLAD1

check button Gene summary
Gene informationGene symbol

FLAD1

Gene ID

80308

Gene nameflavin adenine dinucleotide synthetase 1
SynonymsFAD1|FADS|LSMFLAD|PP591
Cytomap

1q21.3

Type of geneprotein-coding
DescriptionFAD synthaseFAD pyrophosphorylaseFAD-synthetaseFMN adenylyltransferaseFad1, flavin adenine dinucleotide synthetase, homolog
Modification date20180523
UniProtAcc

Q8NFF5

ContextPubMed: FLAD1 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

Top

Exon skipping events across known transcript of Ensembl for FLAD1 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

Top

Gene isoform structures and expression levels for FLAD1

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


Top

Exon skipping events with PSIs in TCGA for FLAD1

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_109841154955813:154955873:154956317:154956542:154959941:154960076154956317:154956542ENSG00000160688.14ENST00000368431.3
exon_skip_109861154955842:154955873:154956317:154956542:154960580:154960643154956317:154956542ENSG00000160688.14ENST00000368432.1,ENST00000315144.10
exon_skip_110061154955906:154956109:154956317:154956542:154960580:154960909154956317:154956542ENSG00000160688.14ENST00000487371.1
exon_skip_110111154956317:154956542:154960580:154961325:154962035:154962183154960580:154961325ENSG00000160688.14ENST00000368433.1,ENST00000368432.1,ENST00000315144.10,ENST00000292180.3
exon_skip_110291154961252:154961325:154962035:154962183:154962634:154962733154962035:154962183ENSG00000160688.14ENST00000368433.1,ENST00000368432.1,ENST00000315144.10,ENST00000292180.3,ENST00000368428.1
exon_skip_110341154961060:154961325:154962634:154962733:154965040:154965149154962634:154962733ENSG00000160688.14ENST00000295530.2,ENST00000405236.2
exon_skip_110351154961060:154961325:154962634:154962733:154965188:154965262154962634:154962733ENSG00000160688.14ENST00000489992.1
exon_skip_110451154962688:154962733:154962814:154963004:154965040:154965149154962814:154963004ENSG00000160688.14ENST00000477609.1
exon_skip_110471154962688:154962733:154962814:154963004:154965188:154965262154962814:154963004ENSG00000160688.14ENST00000368432.1,ENST00000315144.10,ENST00000292180.3

check button PSI values of skipped exons in TCGA.
psi tcga

Top

Exon skipping events with PSIs in GTEx for FLAD1

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_109841154955813:154955873:154956317:154956542:154959941:154960076154956317:154956542ENSG00000160688.14ENST00000368431.3
exon_skip_109861154955842:154955873:154956317:154956542:154960580:154960643154956317:154956542ENSG00000160688.14ENST00000315144.10,ENST00000368432.1
exon_skip_110061154955906:154956109:154956317:154956542:154960580:154960909154956317:154956542ENSG00000160688.14ENST00000487371.1
exon_skip_110111154956317:154956542:154960580:154961325:154962035:154962183154960580:154961325ENSG00000160688.14ENST00000368433.1,ENST00000315144.10,ENST00000368432.1,ENST00000292180.3
exon_skip_110291154961252:154961325:154962035:154962183:154962634:154962733154962035:154962183ENSG00000160688.14ENST00000368433.1,ENST00000315144.10,ENST00000368432.1,ENST00000292180.3,ENST00000368428.1
exon_skip_110341154961060:154961325:154962634:154962733:154965040:154965149154962634:154962733ENSG00000160688.14ENST00000405236.2,ENST00000295530.2
exon_skip_110351154961060:154961325:154962634:154962733:154965188:154965262154962634:154962733ENSG00000160688.14ENST00000489992.1
exon_skip_110451154962688:154962733:154962814:154963004:154965040:154965149154962814:154963004ENSG00000160688.14ENST00000477609.1
exon_skip_110471154962688:154962733:154962814:154963004:154965188:154965262154962814:154963004ENSG00000160688.14ENST00000315144.10,ENST00000368432.1,ENST00000292180.3

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

Top

Open reading frame (ORF) annotation in the exon skipping event for FLAD1

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000292180154960580154961325Frame-shift
ENST00000292180154962035154962183Frame-shift
ENST00000292180154962814154963004Frame-shift

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000292180154960580154961325Frame-shift
ENST00000292180154962035154962183Frame-shift
ENST00000292180154962814154963004Frame-shift

Top

Infer the effects of exon skipping event on protein functional features for FLAD1

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature


Top

SNVs in the skipped exons for FLAD1

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.
FLAD1_HNSC_exon_skip_11029_psi_boxplot.png
boxplot
FLAD1_LIHC_exon_skip_11029_psi_boxplot.png
boxplot
FLAD1_SKCM_exon_skip_11029_psi_boxplot.png
boxplot

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A1EG-01exon_skip_11006
exon_skip_10984
exon_skip_10986
154956318154956542154956356154956356Frame_Shift_DelC-p.G62fs
LIHCTCGA-DD-A1EG-01exon_skip_11011
154960581154961325154961089154961089Frame_Shift_DelC-p.A294fs
HNSCTCGA-CR-7390-01exon_skip_11029
154962036154962183154962050154962050Frame_Shift_DelA-p.K378fs
HNSCTCGA-CR-7390-01exon_skip_11029
154962036154962183154962050154962050Frame_Shift_DelA-p.K379fs
SKCMTCGA-FR-A728-01exon_skip_11029
154962036154962183154962050154962050Frame_Shift_DelA-p.K379fs
LIHCTCGA-DD-A39Y-01exon_skip_11029
154962036154962183154962131154962131Frame_Shift_DelG-p.G406fs
LIHCTCGA-G3-A3CJ-01exon_skip_11047
exon_skip_11045
154962815154963004154962859154962859Frame_Shift_DelC-p.A470fs
SARCTCGA-DX-A6B8-01exon_skip_11006
exon_skip_10984
exon_skip_10986
154956318154956542154956441154956442Frame_Shift_Ins-Tp.G91fs
SARCTCGA-DX-A6B8-01exon_skip_11006
exon_skip_10984
exon_skip_10986
154956318154956542154956441154956442Frame_Shift_Ins-Tp.R91fs
BLCATCGA-S5-A6DX-01exon_skip_11006
exon_skip_10984
exon_skip_10986
154956318154956542154956531154956531Nonsense_MutationGTp.E121*
SKCMTCGA-FW-A3R5-06exon_skip_11011
154960581154961325154960590154960590Nonsense_MutationCTp.Q128*
SKCMTCGA-FW-A3R5-06exon_skip_11011
154960581154961325154960590154960590Nonsense_MutationCTp.Q128X
CESCTCGA-IR-A3LH-01exon_skip_11011
154960581154961325154961004154961004Nonsense_MutationGTp.E266*
BRCATCGA-BH-A1F8-01exon_skip_11011
154960581154961325154961309154961309Nonsense_MutationCGp.Y367*

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description
FLAD1_154961252_154961325_154962035_154962183_154962634_154962733_TCGA-CR-7390-01Sample: TCGA-CR-7390-01
Cancer type: HNSC
ESID: exon_skip_11029
Skipped exon start: 154962036
Skipped exon end: 154962183
Mutation start: 154962050
Mutation end: 154962050
Mutation type: Frame_Shift_Del
Reference seq: A
Mutation seq: -
AAchange: p.K379fs
FLAD1_154961252_154961325_154962035_154962183_154962634_154962733_TCGA-CR-7390-01Sample: TCGA-CR-7390-01
Cancer type: HNSC
ESID: exon_skip_11029
Skipped exon start: 154962036
Skipped exon end: 154962183
Mutation start: 154962050
Mutation end: 154962050
Mutation type: Frame_Shift_Del
Reference seq: A
Mutation seq: -
AAchange: p.K378fs
exon_skip_11029_HNSC_TCGA-CR-7390-01.png
boxplot
exon_skip_14564_HNSC_TCGA-CR-7390-01.png
boxplot
exon_skip_434739_HNSC_TCGA-CR-7390-01.png
boxplot
FLAD1_154961252_154961325_154962035_154962183_154962634_154962733_TCGA-DD-A39Y-01Sample: TCGA-DD-A39Y-01
Cancer type: LIHC
ESID: exon_skip_11029
Skipped exon start: 154962036
Skipped exon end: 154962183
Mutation start: 154962131
Mutation end: 154962131
Mutation type: Frame_Shift_Del
Reference seq: G
Mutation seq: -
AAchange: p.G406fs
exon_skip_105023_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_101824_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_106032_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_106378_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_106523_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_106524_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_109527_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_109529_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_110000_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_11029_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_111893_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_111894_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_112042_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_112647_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_114045_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_114046_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_114565_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_11916_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_1234_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_1237_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_124639_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_124693_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_124695_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_130535_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_13071_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_131505_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_133556_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_135211_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_135545_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_135553_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_135763_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_137564_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_138947_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_139222_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_141370_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_141945_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_143515_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_143728_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_14772_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_148319_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_148332_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_14897_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_150985_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_151979_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_153387_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_153494_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_153786_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_155021_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_155962_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_155964_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_19897_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_19898_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_19902_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_20050_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_20053_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_21823_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_22411_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_22908_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_23470_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_24870_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_25336_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_26316_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_26461_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_26958_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_27038_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_27415_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_283977_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_284046_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_289275_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_291046_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_291218_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_291361_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_292293_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_292562_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_293040_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_293045_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_293052_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_293118_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_293546_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_293549_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_294064_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_294067_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_29565_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_29733_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_299242_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_299287_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_299304_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_299306_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_299307_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_30001_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_300924_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_301267_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_301272_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_302090_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_302094_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_302095_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_302097_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_3064_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_306549_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_30744_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_309425_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_310969_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_311352_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_313264_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_313342_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_313654_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_315571_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_315574_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_316800_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_316803_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_31730_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_317832_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_319816_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_320714_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_320715_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_320801LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_320805_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_321225_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_323910_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_32899_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_329221_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_331329_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_331444_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_332241_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_334248_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_335284_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_337247_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_34018_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_340419_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_34444_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_34446_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_346508_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_346721_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_346953_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_350661_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_352716_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_35400_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_354396_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_359435_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_360259_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_360261_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_360316_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_361235_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_364697_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_365330_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_369483_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_369915_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_371550_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_371589_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_374387_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_374402_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_37475_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_37491_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_374945_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_375131_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_375133_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_375393_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_376191_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_378801_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_379758_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_379855_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_380880_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_3815_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_382091_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_382119_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_382121_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_382417_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_382738_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_383797_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_383994_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_385335_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_387812_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_387826_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_389735_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_39262_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_39479_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_39686_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_422548_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_423337_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_423570_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_424308_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_426528_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_426530_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_427280_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_430528_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_433655_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_434375_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_435237_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_435489_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_436454_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_436487_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_436488_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_436494_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_437675_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_437849_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_439418_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_440194_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_440267_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_441705_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_442657_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_443695_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_444190_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_445458_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_446492_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_446495_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_446671_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_450412_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_450419_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_453010_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_454760_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_456871_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_458039_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_458091_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_45824_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_458292_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_458727_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_459683_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_460515_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_463936_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_464994_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_465641_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_469364_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_470206_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_470208_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_470470_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_470485_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_471015_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_471018_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_471458_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_472524_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_472955_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_475132_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_47552_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_476535_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_477211_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_477637_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_478117_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_47838_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_478401_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_478926_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_483792_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_487634_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_489575_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_490603_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_491406_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_492075_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_492152_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_493904_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_493918_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_493920_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_494000_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_494030_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_494170_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_494284_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_499522_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_503301_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_503593_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_503665_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_504513_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_507316_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_507513_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_50803_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_50804_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_510119_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_512208_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_513207_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_513240_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_5141_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_52393_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_54542_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_55185_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_56398_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_56399_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_56834_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_58444_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_58452_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_5861_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_60290_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_60294_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_60561_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_61147_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_6331_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_6399_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_64652_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_64657_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_65996_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_66666_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_67549_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_68080_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_6817_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_69250_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_70509_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_71759_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_71774_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_73487_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_73796_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_74728_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_75089_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_75391_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_77962_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_78386_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_82069_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_82070_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_83493_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_83494_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_83512_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_83602_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_84090_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_84528_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_87720_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_87721_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_89597_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_93891_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_94842_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_94844_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_96282_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_96298_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_96557_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_96886_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_97738_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_97739_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_9807_LIHC_TCGA-DD-A39Y-01.png
boxplot
exon_skip_98550_LIHC_TCGA-DD-A39Y-01.png
boxplot
FLAD1_154961252_154961325_154962035_154962183_154962634_154962733_TCGA-FR-A728-01Sample: TCGA-FR-A728-01
Cancer type: SKCM
ESID: exon_skip_11029
Skipped exon start: 154962036
Skipped exon end: 154962183
Mutation start: 154962050
Mutation end: 154962050
Mutation type: Frame_Shift_Del
Reference seq: A
Mutation seq: -
AAchange: p.K379fs
exon_skip_11029_SKCM_TCGA-FR-A728-01.png
boxplot
FLAD1_154955842_154955873_154956317_154956542_154960580_154960643_TCGA-DX-A6B8-01Sample: TCGA-DX-A6B8-01
Cancer type: SARC
ESID: exon_skip_10986
Skipped exon start: 154956318
Skipped exon end: 154956542
Mutation start: 154956441
Mutation end: 154956442
Mutation type: Frame_Shift_Ins
Reference seq: -
Mutation seq: T
AAchange: p.G91fs
FLAD1_154955842_154955873_154956317_154956542_154960580_154960643_TCGA-DX-A6B8-01Sample: TCGA-DX-A6B8-01
Cancer type: SARC
ESID: exon_skip_10986
Skipped exon start: 154956318
Skipped exon end: 154956542
Mutation start: 154956441
Mutation end: 154956442
Mutation type: Frame_Shift_Ins
Reference seq: -
Mutation seq: T
AAchange: p.R91fs
exon_skip_10986_SARC_TCGA-DX-A6B8-01.png
boxplot

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
2313287_STOMACH154962815154963004154962925154962926Frame_Shift_Ins-Cp.DP492fs
NCIH23_LUNG154956318154956542154956312154956312Missense_MutationCGp.L48V
HEC1B_ENDOMETRIUM154956318154956542154956519154956519Missense_MutationAGp.I117V
YH13_CENTRAL_NERVOUS_SYSTEM154956318154956542154956522154956522Missense_MutationGCp.V118L
HCC2814_LUNG154960581154961325154960617154960617Missense_MutationCTp.R137W
KASUMI2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154960581154961325154960767154960767Missense_MutationAGp.T187A
OVK18_OVARY154960581154961325154960876154960876Missense_MutationTCp.V223A
IALM_LUNG154960581154961325154960906154960906Missense_MutationCGp.T233R
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154960581154961325154960909154960909Missense_MutationAGp.D234G
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154960581154961325154960918154960918Missense_MutationCTp.T237I
JHUEM1_ENDOMETRIUM154960581154961325154960920154960920Missense_MutationGTp.G238C
KYSE520_OESOPHAGUS154960581154961325154960965154960965Missense_MutationCGp.L253V
PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154960581154961325154961029154961029Missense_MutationACp.N274T
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154960581154961325154961035154961035Missense_MutationCTp.A276V
UACC812_BREAST154960581154961325154961088154961088Missense_MutationGAp.A294T
647V_URINARY_TRACT154960581154961325154961238154961238Missense_MutationGAp.A344T
KMRC1_KIDNEY154960581154961325154961242154961242Missense_MutationGAp.R345H
SNU1033_LARGE_INTESTINE154960581154961325154961257154961257Missense_MutationCTp.S350L
YD38_UPPER_AERODIGESTIVE_TRACT154960581154961325154961257154961257Missense_MutationCTp.S350L
KMOE2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154960581154961325154961312154961312Missense_MutationATp.K368N
CCK81_LARGE_INTESTINE154962036154962183154962075154962075Missense_MutationCGp.T386S
LN319_CENTRAL_NERVOUS_SYSTEM154962036154962183154962107154962107Missense_MutationAGp.T397A
PACADD137_PANCREAS154962635154962733154962682154962682Missense_MutationGAp.S438N
MEG01_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154962635154962733154962710154962711Missense_MutationGTACp.F448L
HEC6_ENDOMETRIUM154962815154963004154962837154962837Missense_MutationGTp.A463S
HDQP1_BREAST154962815154963004154962840154962840Missense_MutationGCp.E464Q
NCIH345_LUNG154962815154963004154962916154962916Missense_MutationGAp.R489H
HEC108_ENDOMETRIUM154962815154963004154962960154962960Missense_MutationAGp.T504A
ISHIKAWAHERAKLIO02ER_ENDOMETRIUM154962815154963004154962975154962975Missense_MutationCTp.P509S
KCL22_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE154956318154956542154956396154956396Nonsense_MutationCTp.R76*
LS411N_LARGE_INTESTINE154960581154961325154960953154960953Nonsense_MutationCTp.R249*

Top

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for FLAD1

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value

Top

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for FLAD1


Top

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for FLAD1


Top

RelatedDrugs for FLAD1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for FLAD1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
FLAD1C0410214Myopathy with Abnormal Lipid Metabolism1UNIPROT