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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for CAPRIN2 |
 Gene summary |
| Gene information | Gene symbol | CAPRIN2 | Gene ID | 65981 |
| Gene name | caprin family member 2 | |
| Synonyms | C1QDC1|EEG-1|EEG1|RNG140 | |
| Cytomap | 12p11.21 | |
| Type of gene | protein-coding | |
| Description | caprin-2C1q domain-containing protein 1RNA granule protein 140cytoplasmic activation/proliferation-associated protein 2gastric cancer multidrug resistance-associated protein | |
| Modification date | 20180519 | |
| UniProtAcc | Q6IMN6 | |
| Context | PubMed: CAPRIN2 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| CAPRIN2 | GO:0030308 | negative regulation of cell growth | 14593112 |
| CAPRIN2 | GO:0032092 | positive regulation of protein binding | 18762581 |
| CAPRIN2 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 18762581 |
| CAPRIN2 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 18762581 |
| CAPRIN2 | GO:0090263 | positive regulation of canonical Wnt signaling pathway | 18762581 |
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Exon skipping events across known transcript of Ensembl for CAPRIN2 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for CAPRIN2 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for CAPRIN2 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_90935 | 12 | 30864499:30864563:30864672:30864716:30866718:30866819 | 30864672:30864716 | ENSG00000110888.13 | ENST00000433722.2 |
| exon_skip_90940 | 12 | 30866718:30866819:30867892:30868015:30869441:30869610 | 30867892:30868015 | ENSG00000110888.13 | ENST00000395805.2 |
| exon_skip_90943 | 12 | 30866718:30866819:30867892:30868075:30869441:30869610 | 30867892:30868075 | ENSG00000110888.13 | ENST00000308433.5,ENST00000454014.2,ENST00000298892.5,ENST00000417045.1,ENST00000433722.2 |
| exon_skip_90946 | 12 | 30866718:30866819:30867892:30868078:30869441:30869610 | 30867892:30868078 | ENSG00000110888.13 | ENST00000548676.1,ENST00000251071.5 |
| exon_skip_90984 | 12 | 30869556:30869610:30872012:30872159:30873744:30873849 | 30872012:30872159 | ENSG00000110888.13 | ENST00000308433.5,ENST00000454014.2,ENST00000548676.1,ENST00000417045.1,ENST00000537108.1,ENST00000251071.5,ENST00000433722.2 |
| exon_skip_90985 | 12 | 30869556:30869610:30872012:30872159:30876192:30876248 | 30872012:30872159 | ENSG00000110888.13 | ENST00000395805.2 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENSG00000110888.13 | ENST00000537553.1 |
| exon_skip_90992 | 12 | 30869556:30869610:30873744:30873849:30876192:30876248 | 30873744:30873849 | ENSG00000110888.13 | ENST00000298892.5 |
| exon_skip_90994 | 12 | 30872012:30872159:30873744:30873849:30876192:30876248 | 30873744:30873849 | ENSG00000110888.13 | ENST00000308433.5,ENST00000454014.2,ENST00000548676.1,ENST00000417045.1,ENST00000537108.1,ENST00000251071.5,ENST00000433722.2 |
| exon_skip_90997 | 12 | 30877303:30877385:30878899:30879022:30881581:30882259 | 30878899:30879022 | ENSG00000110888.13 | ENST00000308433.5,ENST00000454014.2,ENST00000298892.5,ENST00000548676.1,ENST00000417045.1,ENST00000537108.1,ENST00000251071.5,ENST00000395805.2,ENST00000433722.2,ENST00000537553.1 |
| exon_skip_90999 | 12 | 30883172:30883216:30884276:30884444:30887901:30887948 | 30884276:30884444 | ENSG00000110888.13 | ENST00000308433.5,ENST00000454014.2,ENST00000548676.1,ENST00000537553.1 |
| exon_skip_91000 | 12 | 30884403:30884444:30886562:30886645:30887901:30887948 | 30886562:30886645 | ENSG00000110888.13 | ENST00000298892.5,ENST00000417045.1,ENST00000537108.1,ENST00000251071.5,ENST00000395805.2,ENST00000433722.2 |
| exon_skip_91004 | 12 | 30888109:30888140:30893953:30894040:30904004:30904058 | 30893953:30894040 | ENSG00000110888.13 | ENST00000308433.5,ENST00000546129.1,ENST00000540436.1,ENST00000454014.2,ENST00000298892.5,ENST00000548676.1,ENST00000534897.1,ENST00000417045.1,ENST00000540584.1,ENST00000537108.1,ENST00000251071.5,ENST00000395805.2,ENST00000542550.1,ENST00000541765.1,ENS |
| exon_skip_91005 | 12 | 30893953:30894040:30904004:30904067:30906277:30906472 | 30904004:30904067 | ENSG00000110888.13 | ENST00000308433.5,ENST00000540436.1,ENST00000454014.2,ENST00000298892.5,ENST00000417045.1,ENST00000540584.1,ENST00000537108.1,ENST00000251071.5,ENST00000395805.2,ENST00000542550.1 |
| exon_skip_91009 | 12 | 30904004:30904067:30906277:30906493:30907614:30907787 | 30906277:30906493 | ENSG00000110888.13 | ENST00000542550.1 |
| exon_skip_91010 | 12 | 30904004:30904067:30906277:30906493:30907622:30907794 | 30906277:30906493 | ENSG00000110888.13 | ENST00000540584.1 |
| exon_skip_91011 | 12 | 30904004:30904067:30906277:30906493:30907684:30907822 | 30906277:30906493 | ENSG00000110888.13 | ENST00000540436.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for CAPRIN2 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_90935 | 12 | 30864499:30864563:30864672:30864716:30866718:30866819 | 30864672:30864716 | ENSG00000110888.13 | ENST00000433722.2 |
| exon_skip_90940 | 12 | 30866718:30866819:30867892:30868015:30869441:30869610 | 30867892:30868015 | ENSG00000110888.13 | ENST00000395805.2 |
| exon_skip_90943 | 12 | 30866718:30866819:30867892:30868075:30869441:30869610 | 30867892:30868075 | ENSG00000110888.13 | ENST00000433722.2,ENST00000298892.5,ENST00000454014.2,ENST00000308433.5,ENST00000417045.1 |
| exon_skip_90946 | 12 | 30866718:30866819:30867892:30868078:30869441:30869610 | 30867892:30868078 | ENSG00000110888.13 | ENST00000548676.1,ENST00000251071.5 |
| exon_skip_90984 | 12 | 30869556:30869610:30872012:30872159:30873744:30873849 | 30872012:30872159 | ENSG00000110888.13 | ENST00000433722.2,ENST00000548676.1,ENST00000454014.2,ENST00000251071.5,ENST00000308433.5,ENST00000417045.1,ENST00000537108.1 |
| exon_skip_90985 | 12 | 30869556:30869610:30872012:30872159:30876192:30876248 | 30872012:30872159 | ENSG00000110888.13 | ENST00000395805.2 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENSG00000110888.13 | ENST00000537553.1 |
| exon_skip_90992 | 12 | 30869556:30869610:30873744:30873849:30876192:30876248 | 30873744:30873849 | ENSG00000110888.13 | ENST00000298892.5 |
| exon_skip_90994 | 12 | 30872012:30872159:30873744:30873849:30876192:30876248 | 30873744:30873849 | ENSG00000110888.13 | ENST00000433722.2,ENST00000548676.1,ENST00000454014.2,ENST00000251071.5,ENST00000308433.5,ENST00000417045.1,ENST00000537108.1 |
| exon_skip_90997 | 12 | 30877303:30877385:30878899:30879022:30881581:30882259 | 30878899:30879022 | ENSG00000110888.13 | ENST00000537553.1,ENST00000433722.2,ENST00000548676.1,ENST00000298892.5,ENST00000454014.2,ENST00000395805.2,ENST00000251071.5,ENST00000308433.5,ENST00000417045.1,ENST00000537108.1 |
| exon_skip_90999 | 12 | 30883172:30883216:30884276:30884444:30887901:30887948 | 30884276:30884444 | ENSG00000110888.13 | ENST00000537553.1,ENST00000548676.1,ENST00000454014.2,ENST00000308433.5 |
| exon_skip_91000 | 12 | 30884403:30884444:30886562:30886645:30887901:30887948 | 30886562:30886645 | ENSG00000110888.13 | ENST00000433722.2,ENST00000298892.5,ENST00000395805.2,ENST00000251071.5,ENST00000417045.1,ENST00000537108.1 |
| exon_skip_91004 | 12 | 30888109:30888140:30893953:30894040:30904004:30904058 | 30893953:30894040 | ENSG00000110888.13 | ENST00000548676.1,ENST00000298892.5,ENST00000454014.2,ENST00000395805.2,ENST00000251071.5,ENST00000308433.5,ENST00000417045.1,ENST00000537108.1,ENST00000534897.1,ENST00000541765.1,ENST00000543380.1,ENST00000546129.1,ENST00000542550.1,ENST00000540436.1,ENS |
| exon_skip_91005 | 12 | 30893953:30894040:30904004:30904067:30906277:30906472 | 30904004:30904067 | ENSG00000110888.13 | ENST00000298892.5,ENST00000454014.2,ENST00000395805.2,ENST00000251071.5,ENST00000308433.5,ENST00000417045.1,ENST00000537108.1,ENST00000542550.1,ENST00000540436.1,ENST00000540584.1 |
| exon_skip_91009 | 12 | 30904004:30904067:30906277:30906493:30907614:30907787 | 30906277:30906493 | ENSG00000110888.13 | ENST00000542550.1 |
| exon_skip_91010 | 12 | 30904004:30904067:30906277:30906493:30907622:30907794 | 30906277:30906493 | ENSG00000110888.13 | ENST00000540584.1 |
| exon_skip_91011 | 12 | 30904004:30904067:30906277:30906493:30907684:30907822 | 30906277:30906493 | ENSG00000110888.13 | ENST00000540436.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for CAPRIN2 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
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Infer the effects of exon skipping event on protein functional features for CAPRIN2 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for CAPRIN2 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_90984 exon_skip_90985 | 30872013 | 30872159 | 30872146 | 30872146 | Frame_Shift_Del | G | - | p.P721fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_90991 | 30872013 | 30873849 | 30872146 | 30872146 | Frame_Shift_Del | G | - | p.P721fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_90984 exon_skip_90985 | 30872013 | 30872159 | 30872146 | 30872146 | Frame_Shift_Del | G | - | p.P721fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_90991 | 30872013 | 30873849 | 30872146 | 30872146 | Frame_Shift_Del | G | - | p.P721fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_90991 | 30872013 | 30873849 | 30873828 | 30873828 | Frame_Shift_Del | A | - | p.C689fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_90992 exon_skip_90994 | 30873745 | 30873849 | 30873828 | 30873828 | Frame_Shift_Del | A | - | p.C689fs |
| LIHC | TCGA-DD-A3A0-01 | 30878900 | 30879022 | 30878948 | 30878948 | Frame_Shift_Del | T | - | p.K619fs | |
| COAD | TCGA-A6-6781-01 | exon_skip_90999 | 30884277 | 30884444 | 30884313 | 30884313 | Frame_Shift_Del | T | - | p.T342fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_90999 | 30884277 | 30884444 | 30884313 | 30884313 | Frame_Shift_Del | T | - | p.T342fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_90999 | 30884277 | 30884444 | 30884395 | 30884395 | Frame_Shift_Del | A | - | p.F314fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_91004 | 30893954 | 30894040 | 30893977 | 30893977 | Frame_Shift_Del | T | - | p.T183fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_91005 | 30904005 | 30904067 | 30904034 | 30904034 | Frame_Shift_Del | T | - | p.S152fs |
| UCEC | TCGA-AP-A0LT-01 | exon_skip_91009 exon_skip_91011 exon_skip_91010 | 30906278 | 30906493 | 30906412 | 30906412 | Frame_Shift_Del | C | - | p.E96fs |
| LIHC | TCGA-BC-A112-01 | exon_skip_91009 exon_skip_91011 exon_skip_91010 | 30906278 | 30906493 | 30906281 | 30906282 | Frame_Shift_Ins | - | T | p.K139fs |
| LIHC | TCGA-BC-A112-01 | exon_skip_91009 exon_skip_91011 exon_skip_91010 | 30906278 | 30906493 | 30906300 | 30906301 | Frame_Shift_Ins | - | T | p.*133fs |
| LIHC | TCGA-BC-A112-01 | exon_skip_91009 exon_skip_91011 exon_skip_91010 | 30906278 | 30906493 | 30906387 | 30906388 | Frame_Shift_Ins | - | G | p.A104fs |
| LUSC | TCGA-33-4586-01 | exon_skip_90940 | 30867893 | 30868015 | 30868013 | 30868013 | Nonsense_Mutation | G | A | p.Q844* |
| LUSC | TCGA-33-4586-01 | exon_skip_90943 | 30867893 | 30868075 | 30868013 | 30868013 | Nonsense_Mutation | G | A | p.Q844* |
| LUSC | TCGA-33-4586-01 | exon_skip_90946 | 30867893 | 30868078 | 30868013 | 30868013 | Nonsense_Mutation | G | A | p.Q844* |
| BLCA | TCGA-S5-A6DX-01 | exon_skip_90984 exon_skip_90985 | 30872013 | 30872159 | 30872128 | 30872128 | Nonsense_Mutation | G | T | p.S727* |
| BLCA | TCGA-S5-A6DX-01 | exon_skip_90991 | 30872013 | 30873849 | 30872128 | 30872128 | Nonsense_Mutation | G | T | p.S727* |
| HNSC | TCGA-CV-A468-01 | 30878900 | 30879022 | 30878929 | 30878929 | Nonsense_Mutation | G | A | p.Q626* | |
| BRCA | TCGA-EW-A1IZ-01 | exon_skip_91005 | 30904005 | 30904067 | 30904069 | 30904069 | Splice_Site | T | C | e2-2 |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| 42MGBA_CENTRAL_NERVOUS_SYSTEM | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| BCPAP_THYROID | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| HS274T_BREAST | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| HS934T_FIBROBLAST | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| JVM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| KMS20_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| LN340_CENTRAL_NERVOUS_SYSTEM | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| MCF7_BREAST | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| NCIH2106_LUNG | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| NCIH292_LUNG | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| PL21_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| RERFGC1B_STOMACH | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| RPMI7951_SKIN | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| RS5_FIBROBLAST | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| SNU119_OVARY | 30884277 | 30884444 | 30884312 | 30884313 | Frame_Shift_Ins | - | T | p.T342fs |
| JHUEM7_ENDOMETRIUM | 30867893 | 30868078 | 30867923 | 30867923 | Missense_Mutation | T | C | p.N818D |
| JHUEM7_ENDOMETRIUM | 30867893 | 30868015 | 30867923 | 30867923 | Missense_Mutation | T | C | p.N818D |
| JHUEM7_ENDOMETRIUM | 30867893 | 30868075 | 30867923 | 30867923 | Missense_Mutation | T | C | p.N818D |
| KD_SOFT_TISSUE | 30867893 | 30868078 | 30867934 | 30867934 | Missense_Mutation | C | T | p.R814K |
| KD_SOFT_TISSUE | 30867893 | 30868015 | 30867934 | 30867934 | Missense_Mutation | C | T | p.R814K |
| KD_SOFT_TISSUE | 30867893 | 30868075 | 30867934 | 30867934 | Missense_Mutation | C | T | p.R814K |
| SNU5_STOMACH | 30867893 | 30868078 | 30867969 | 30867969 | Missense_Mutation | G | T | p.S802R |
| SNU5_STOMACH | 30867893 | 30868015 | 30867969 | 30867969 | Missense_Mutation | G | T | p.S802R |
| SNU5_STOMACH | 30867893 | 30868075 | 30867969 | 30867969 | Missense_Mutation | G | T | p.S802R |
| NCIH1793_LUNG | 30872013 | 30873849 | 30872016 | 30872016 | Missense_Mutation | C | A | p.Q729H |
| NCIH1793_LUNG | 30872013 | 30872159 | 30872016 | 30872016 | Missense_Mutation | C | A | p.Q729H |
| LS411N_LARGE_INTESTINE | 30872013 | 30873849 | 30872019 | 30872019 | Missense_Mutation | C | T | p.M728I |
| LS411N_LARGE_INTESTINE | 30872013 | 30872159 | 30872019 | 30872019 | Missense_Mutation | C | T | p.M728I |
| EN_ENDOMETRIUM | 30872013 | 30873849 | 30872104 | 30872104 | Missense_Mutation | A | G | p.M700T |
| EN_ENDOMETRIUM | 30872013 | 30872159 | 30872104 | 30872104 | Missense_Mutation | A | G | p.M700T |
| OCUBM_BREAST | 30872013 | 30873849 | 30872119 | 30872119 | Missense_Mutation | G | A | p.S695F |
| OCUBM_BREAST | 30872013 | 30872159 | 30872119 | 30872119 | Missense_Mutation | G | A | p.S695F |
| MFE296_ENDOMETRIUM | 30873745 | 30873849 | 30873801 | 30873801 | Missense_Mutation | T | C | p.T698A |
| MFE296_ENDOMETRIUM | 30872013 | 30873849 | 30873801 | 30873801 | Missense_Mutation | T | C | p.T698A |
| NCIH716_LARGE_INTESTINE | 30873745 | 30873849 | 30873845 | 30873845 | Missense_Mutation | G | T | p.T683N |
| NCIH716_LARGE_INTESTINE | 30872013 | 30873849 | 30873845 | 30873845 | Missense_Mutation | G | T | p.T683N |
| CAL62_THYROID | 30884277 | 30884444 | 30884352 | 30884352 | Missense_Mutation | G | A | p.P329S |
| DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 30886563 | 30886645 | 30886581 | 30886581 | Missense_Mutation | C | T | p.A292T |
| IGROV1_OVARY | 30906278 | 30906493 | 30906289 | 30906289 | Missense_Mutation | C | T | p.E137K |
| NCIH2023_LUNG | 30906278 | 30906493 | 30906325 | 30906325 | Missense_Mutation | C | G | p.G125R |
| RCCFG2_KIDNEY | 30906278 | 30906493 | 30906339 | 30906339 | Missense_Mutation | G | A | p.T120I |
| MRKNU1_BREAST | 30906278 | 30906493 | 30906439 | 30906439 | Missense_Mutation | G | C | p.P87A |
| HEC108_ENDOMETRIUM | 30884277 | 30884444 | 30884328 | 30884328 | Nonsense_Mutation | G | A | p.Q337* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CAPRIN2 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | ESCA | rs73079962 | chr12:30872178 | G/A | 6.39e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | ESCA | rs73079966 | chr12:30872530 | G/A | 6.39e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | ESCA | rs73079970 | chr12:30873116 | C/T | 6.39e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | ESCA | rs73079971 | chr12:30873311 | T/C | 6.39e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | ESCA | rs73079965 | chr12:30872290 | T/C | 6.85e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | BRCA | rs73079971 | chr12:30873311 | T/C | 3.85e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | BRCA | rs73079966 | chr12:30872530 | G/A | 1.00e-04 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | BRCA | rs73079970 | chr12:30873116 | C/T | 1.00e-04 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | BRCA | rs73079962 | chr12:30872178 | G/A | 1.84e-04 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | BRCA | rs73079965 | chr12:30872290 | T/C | 1.84e-04 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | LGG | rs73079966 | chr12:30872530 | G/A | 7.37e-10 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | LGG | rs73079970 | chr12:30873116 | C/T | 7.37e-10 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | LGG | rs73079971 | chr12:30873311 | T/C | 1.93e-09 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | LGG | rs73079962 | chr12:30872178 | G/A | 2.17e-09 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | LGG | rs73079965 | chr12:30872290 | T/C | 2.17e-09 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | LGG | rs12370429 | chr12:30873049 | A/G | 7.70e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | KIRC | rs12370429 | chr12:30873049 | A/G | 1.56e-03 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | PRAD | rs12370429 | chr12:30873049 | A/G | 9.09e-05 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | PRAD | rs73079966 | chr12:30872530 | G/A | 1.09e-03 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | PRAD | rs73079970 | chr12:30873116 | C/T | 1.09e-03 |
| exon_skip_90991 | 12 | 30869556:30869610:30872012:30873849:30876192:30876248 | 30872012:30873849 | ENST00000537553.1 | PRAD | rs73079971 | chr12:30873311 | T/C | 1.09e-03 |
| exon_skip_90946 | 12 | 30866718:30866819:30867892:30868078:30869441:30869610 | 30867892:30868078 | ENST00000548676.1,ENST00000251071.5 | LGG | rs13656 | chr12:30868002 | C/T | 8.66e-05 |
| exon_skip_90946 | 12 | 30866718:30866819:30867892:30868078:30869441:30869610 | 30867892:30868078 | ENST00000548676.1,ENST00000251071.5 | KIRC | rs13656 | chr12:30868002 | C/T | 2.75e-03 |
| exon_skip_90946 | 12 | 30866718:30866819:30867892:30868078:30869441:30869610 | 30867892:30868078 | ENST00000548676.1,ENST00000251071.5 | PRAD | rs13656 | chr12:30868002 | C/T | 5.32e-05 |
| exon_skip_90940 | 12 | 30866718:30866819:30867892:30868015:30869441:30869610 | 30867892:30868015 | ENST00000395805.2 | LGG | rs13656 | chr12:30868002 | C/T | 8.66e-05 |
| exon_skip_90940 | 12 | 30866718:30866819:30867892:30868015:30869441:30869610 | 30867892:30868015 | ENST00000395805.2 | KIRC | rs13656 | chr12:30868002 | C/T | 2.75e-03 |
| exon_skip_90940 | 12 | 30866718:30866819:30867892:30868015:30869441:30869610 | 30867892:30868015 | ENST00000395805.2 | PRAD | rs13656 | chr12:30868002 | C/T | 5.32e-05 |
| exon_skip_90943 | 12 | 30866718:30866819:30867892:30868075:30869441:30869610 | 30867892:30868075 | ENST00000308433.5,ENST00000454014.2,ENST00000298892.5,ENST00000417045.1,ENST00000433722.2 | LGG | rs13656 | chr12:30868002 | C/T | 8.66e-05 |
| exon_skip_90943 | 12 | 30866718:30866819:30867892:30868075:30869441:30869610 | 30867892:30868075 | ENST00000308433.5,ENST00000454014.2,ENST00000298892.5,ENST00000417045.1,ENST00000433722.2 | KIRC | rs13656 | chr12:30868002 | C/T | 2.75e-03 |
| exon_skip_90943 | 12 | 30866718:30866819:30867892:30868075:30869441:30869610 | 30867892:30868075 | ENST00000308433.5,ENST00000454014.2,ENST00000298892.5,ENST00000417045.1,ENST00000433722.2 | PRAD | rs13656 | chr12:30868002 | C/T | 5.32e-05 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CAPRIN2 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CAPRIN2 |
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RelatedDrugs for CAPRIN2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CAPRIN2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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