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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for USP37 |
 Gene summary |
| Gene information | Gene symbol | USP37 | Gene ID | 57695 |
| Gene name | ubiquitin specific peptidase 37 | |
| Synonyms | - | |
| Cytomap | 2q35 | |
| Type of gene | protein-coding | |
| Description | ubiquitin carboxyl-terminal hydrolase 37deubiquitinating enzyme 37tmp_locus_50ubiquitin specific protease 37ubiquitin thioesterase 37ubiquitin thiolesterase 37ubiquitin-specific-processing protease 37 | |
| Modification date | 20180523 | |
| UniProtAcc | Q86T82 | |
| Context | PubMed: USP37 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| USP37 | GO:0000082 | G1/S transition of mitotic cell cycle | 21596315 |
| USP37 | GO:0016579 | protein deubiquitination | 14715245 |
| USP37 | GO:0035871 | protein K11-linked deubiquitination | 21596315 |
| USP37 | GO:0071108 | protein K48-linked deubiquitination | 21596315 |
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Exon skipping events across known transcript of Ensembl for USP37 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for USP37 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for USP37 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_346759 | 2 | 219319537:219319740:219320302:219320441:219321814:219321884 | 219320302:219320441 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346760 | 2 | 219320302:219320441:219321814:219321884:219324512:219324628 | 219321814:219321884 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346761 | 2 | 219321814:219321884:219324512:219324628:219328028:219328089 | 219324512:219324628 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346762 | 2 | 219324512:219324628:219328028:219328089:219330732:219330899 | 219328028:219328089 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346763 | 2 | 219328028:219328089:219330732:219330899:219339352:219339608 | 219330732:219330899 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346764 | 2 | 219330855:219330899:219337912:219337969:219339352:219339608 | 219337912:219337969 | ENSG00000135913.6 | ENST00000473554.1 |
| exon_skip_346766 | 2 | 219341665:219341704:219344372:219344438:219346792:219346957 | 219344372:219344438 | ENSG00000135913.6 | ENST00000258399.3,ENST00000475553.1,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346768 | 2 | 219350386:219350466:219353026:219353144:219360482:219360673 | 219353026:219353144 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346769 | 2 | 219362748:219362880:219374701:219374863:219394678:219394763 | 219374701:219374863 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346770 | 2 | 219374729:219374863:219394678:219394763:219399331:219399429 | 219394678:219394763 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1 |
| exon_skip_346771 | 2 | 219374729:219374863:219394678:219394763:219410943:219411021 | 219394678:219394763 | ENSG00000135913.6 | ENST00000478329.1 |
| exon_skip_346773 | 2 | 219394678:219394763:219399331:219399429:219410943:219411021 | 219399331:219399429 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1,ENST00000338465.5 |
| exon_skip_346775 | 2 | 219411641:219411814:219414531:219414632:219418275:219418447 | 219414531:219414632 | ENSG00000135913.6 | ENST00000415516.1,ENST00000258399.3,ENST00000454775.1,ENST00000418019.1,ENST00000338465.5 |
| exon_skip_346778 | 2 | 219418275:219418447:219423220:219423400:219425542:219425606 | 219423220:219423400 | ENSG00000135913.6 | ENST00000258399.3,ENST00000418019.1,ENST00000338465.5 |
| exon_skip_346780 | 2 | 219418275:219418447:219423220:219423440:219425542:219425606 | 219423220:219423440 | ENSG00000135913.6 | ENST00000454775.1 |
| exon_skip_346782 | 2 | 219423220:219423400:219425542:219425606:219427395:219427536 | 219425542:219425606 | ENSG00000135913.6 | ENST00000258399.3,ENST00000338465.5 |
| exon_skip_346783 | 2 | 219423220:219423400:219425542:219425606:219427440:219427536 | 219425542:219425606 | ENSG00000135913.6 | ENST00000418019.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for USP37 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_346759 | 2 | 219319537:219319740:219320302:219320441:219321814:219321884 | 219320302:219320441 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346760 | 2 | 219320302:219320441:219321814:219321884:219324512:219324628 | 219321814:219321884 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346761 | 2 | 219321814:219321884:219324512:219324628:219328028:219328089 | 219324512:219324628 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346762 | 2 | 219324512:219324628:219328028:219328089:219330732:219330899 | 219328028:219328089 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346763 | 2 | 219328028:219328089:219330732:219330899:219339352:219339608 | 219330732:219330899 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346764 | 2 | 219330855:219330899:219337912:219337969:219339352:219339608 | 219337912:219337969 | ENSG00000135913.6 | ENST00000473554.1 |
| exon_skip_346766 | 2 | 219341665:219341704:219344372:219344438:219346792:219346957 | 219344372:219344438 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000418019.1,ENST00000475553.1 |
| exon_skip_346768 | 2 | 219350386:219350466:219353026:219353144:219360482:219360673 | 219353026:219353144 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346769 | 2 | 219362748:219362880:219374701:219374863:219394678:219394763 | 219374701:219374863 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346770 | 2 | 219374729:219374863:219394678:219394763:219399331:219399429 | 219394678:219394763 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1 |
| exon_skip_346771 | 2 | 219374729:219374863:219394678:219394763:219410943:219411021 | 219394678:219394763 | ENSG00000135913.6 | ENST00000478329.1 |
| exon_skip_346773 | 2 | 219394678:219394763:219399331:219399429:219410943:219411021 | 219399331:219399429 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1,ENST00000338465.5 |
| exon_skip_346774 | 2 | 219410943:219411021:219411641:219411814:219414531:219414547 | 219411641:219411814 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1,ENST00000478329.1,ENST00000338465.5 |
| exon_skip_346775 | 2 | 219411641:219411814:219414531:219414632:219418275:219418447 | 219414531:219414632 | ENSG00000135913.6 | ENST00000258399.3,ENST00000454775.1,ENST00000415516.1,ENST00000418019.1,ENST00000338465.5 |
| exon_skip_346778 | 2 | 219418275:219418447:219423220:219423400:219425542:219425606 | 219423220:219423400 | ENSG00000135913.6 | ENST00000258399.3,ENST00000418019.1,ENST00000338465.5 |
| exon_skip_346780 | 2 | 219418275:219418447:219423220:219423440:219425542:219425606 | 219423220:219423440 | ENSG00000135913.6 | ENST00000454775.1 |
| exon_skip_346782 | 2 | 219423220:219423400:219425542:219425606:219427395:219427536 | 219425542:219425606 | ENSG00000135913.6 | ENST00000258399.3,ENST00000338465.5 |
| exon_skip_346783 | 2 | 219423220:219423400:219425542:219425606:219427440:219427536 | 219425542:219425606 | ENSG00000135913.6 | ENST00000418019.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for USP37 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000258399 | 219423220 | 219423400 | 3UTR-3CDS |
| ENST00000418019 | 219423220 | 219423400 | 3UTR-3CDS |
| ENST00000454775 | 219423220 | 219423440 | 3UTR-3CDS |
| ENST00000258399 | 219425542 | 219425606 | 3UTR-3UTR |
| ENST00000418019 | 219425542 | 219425606 | 3UTR-3UTR |
| ENST00000258399 | 219320302 | 219320441 | Frame-shift |
| ENST00000418019 | 219320302 | 219320441 | Frame-shift |
| ENST00000454775 | 219320302 | 219320441 | Frame-shift |
| ENST00000258399 | 219321814 | 219321884 | Frame-shift |
| ENST00000418019 | 219321814 | 219321884 | Frame-shift |
| ENST00000454775 | 219321814 | 219321884 | Frame-shift |
| ENST00000258399 | 219324512 | 219324628 | Frame-shift |
| ENST00000418019 | 219324512 | 219324628 | Frame-shift |
| ENST00000454775 | 219324512 | 219324628 | Frame-shift |
| ENST00000258399 | 219328028 | 219328089 | Frame-shift |
| ENST00000418019 | 219328028 | 219328089 | Frame-shift |
| ENST00000454775 | 219328028 | 219328089 | Frame-shift |
| ENST00000258399 | 219330732 | 219330899 | Frame-shift |
| ENST00000418019 | 219330732 | 219330899 | Frame-shift |
| ENST00000454775 | 219330732 | 219330899 | Frame-shift |
| ENST00000258399 | 219353026 | 219353144 | Frame-shift |
| ENST00000418019 | 219353026 | 219353144 | Frame-shift |
| ENST00000454775 | 219353026 | 219353144 | Frame-shift |
| ENST00000258399 | 219394678 | 219394763 | Frame-shift |
| ENST00000418019 | 219394678 | 219394763 | Frame-shift |
| ENST00000454775 | 219394678 | 219394763 | Frame-shift |
| ENST00000258399 | 219399331 | 219399429 | Frame-shift |
| ENST00000418019 | 219399331 | 219399429 | Frame-shift |
| ENST00000454775 | 219399331 | 219399429 | Frame-shift |
| ENST00000258399 | 219414531 | 219414632 | Frame-shift |
| ENST00000418019 | 219414531 | 219414632 | Frame-shift |
| ENST00000454775 | 219414531 | 219414632 | Frame-shift |
| ENST00000258399 | 219344372 | 219344438 | In-frame |
| ENST00000418019 | 219344372 | 219344438 | In-frame |
| ENST00000454775 | 219344372 | 219344438 | In-frame |
| ENST00000258399 | 219374701 | 219374863 | In-frame |
| ENST00000418019 | 219374701 | 219374863 | In-frame |
| ENST00000454775 | 219374701 | 219374863 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000258399 | 219423220 | 219423400 | 3UTR-3CDS |
| ENST00000418019 | 219423220 | 219423400 | 3UTR-3CDS |
| ENST00000454775 | 219423220 | 219423440 | 3UTR-3CDS |
| ENST00000258399 | 219425542 | 219425606 | 3UTR-3UTR |
| ENST00000418019 | 219425542 | 219425606 | 3UTR-3UTR |
| ENST00000258399 | 219320302 | 219320441 | Frame-shift |
| ENST00000418019 | 219320302 | 219320441 | Frame-shift |
| ENST00000454775 | 219320302 | 219320441 | Frame-shift |
| ENST00000258399 | 219321814 | 219321884 | Frame-shift |
| ENST00000418019 | 219321814 | 219321884 | Frame-shift |
| ENST00000454775 | 219321814 | 219321884 | Frame-shift |
| ENST00000258399 | 219324512 | 219324628 | Frame-shift |
| ENST00000418019 | 219324512 | 219324628 | Frame-shift |
| ENST00000454775 | 219324512 | 219324628 | Frame-shift |
| ENST00000258399 | 219328028 | 219328089 | Frame-shift |
| ENST00000418019 | 219328028 | 219328089 | Frame-shift |
| ENST00000454775 | 219328028 | 219328089 | Frame-shift |
| ENST00000258399 | 219330732 | 219330899 | Frame-shift |
| ENST00000418019 | 219330732 | 219330899 | Frame-shift |
| ENST00000454775 | 219330732 | 219330899 | Frame-shift |
| ENST00000258399 | 219353026 | 219353144 | Frame-shift |
| ENST00000418019 | 219353026 | 219353144 | Frame-shift |
| ENST00000454775 | 219353026 | 219353144 | Frame-shift |
| ENST00000258399 | 219394678 | 219394763 | Frame-shift |
| ENST00000418019 | 219394678 | 219394763 | Frame-shift |
| ENST00000454775 | 219394678 | 219394763 | Frame-shift |
| ENST00000258399 | 219399331 | 219399429 | Frame-shift |
| ENST00000418019 | 219399331 | 219399429 | Frame-shift |
| ENST00000454775 | 219399331 | 219399429 | Frame-shift |
| ENST00000258399 | 219411641 | 219411814 | Frame-shift |
| ENST00000418019 | 219411641 | 219411814 | Frame-shift |
| ENST00000454775 | 219411641 | 219411814 | Frame-shift |
| ENST00000258399 | 219414531 | 219414632 | Frame-shift |
| ENST00000418019 | 219414531 | 219414632 | Frame-shift |
| ENST00000454775 | 219414531 | 219414632 | Frame-shift |
| ENST00000258399 | 219344372 | 219344438 | In-frame |
| ENST00000418019 | 219344372 | 219344438 | In-frame |
| ENST00000454775 | 219344372 | 219344438 | In-frame |
| ENST00000258399 | 219374701 | 219374863 | In-frame |
| ENST00000418019 | 219374701 | 219374863 | In-frame |
| ENST00000454775 | 219374701 | 219374863 | In-frame |
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Infer the effects of exon skipping event on protein functional features for USP37 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000258399 | 8049 | 979 | 219374701 | 219374863 | 1277 | 1438 | 288 | 341 |
| ENST00000418019 | 3370 | 979 | 219374701 | 219374863 | 1162 | 1323 | 288 | 341 |
| ENST00000454775 | 5036 | 979 | 219374701 | 219374863 | 1281 | 1442 | 288 | 341 |
| ENST00000258399 | 8049 | 979 | 219344372 | 219344438 | 2249 | 2314 | 612 | 633 |
| ENST00000418019 | 3370 | 979 | 219344372 | 219344438 | 2134 | 2199 | 612 | 633 |
| ENST00000454775 | 5036 | 979 | 219344372 | 219344438 | 2253 | 2318 | 612 | 633 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000258399 | 8049 | 979 | 219374701 | 219374863 | 1277 | 1438 | 288 | 341 |
| ENST00000418019 | 3370 | 979 | 219374701 | 219374863 | 1162 | 1323 | 288 | 341 |
| ENST00000454775 | 5036 | 979 | 219374701 | 219374863 | 1281 | 1442 | 288 | 341 |
| ENST00000258399 | 8049 | 979 | 219344372 | 219344438 | 2249 | 2314 | 612 | 633 |
| ENST00000418019 | 3370 | 979 | 219344372 | 219344438 | 2134 | 2199 | 612 | 633 |
| ENST00000454775 | 5036 | 979 | 219344372 | 219344438 | 2253 | 2318 | 612 | 633 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for USP37 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_346761 | 219324513 | 219324628 | 219324520 | 219324520 | Frame_Shift_Del | T | - | p.N879fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_346761 | 219324513 | 219324628 | 219324564 | 219324564 | Frame_Shift_Del | A | - | p.F864fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_346768 | 219353027 | 219353144 | 219353075 | 219353075 | Frame_Shift_Del | T | - | p.K514fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_346768 | 219353027 | 219353144 | 219353075 | 219353075 | Frame_Shift_Del | T | - | p.K514fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_346768 | 219353027 | 219353144 | 219353122 | 219353122 | Frame_Shift_Del | T | - | p.R499fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_346768 | 219353027 | 219353144 | 219353126 | 219353126 | Frame_Shift_Del | G | - | p.P497fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_346773 | 219399332 | 219399429 | 219399361 | 219399361 | Frame_Shift_Del | A | - | p.L250fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_346773 | 219399332 | 219399429 | 219399373 | 219399373 | Frame_Shift_Del | T | - | p.K246fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_346773 | 219399332 | 219399429 | 219399405 | 219399405 | Frame_Shift_Del | G | - | p.P235fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_346775 | 219414532 | 219414632 | 219414587 | 219414587 | Frame_Shift_Del | C | - | p.G125fs |
| LIHC | TCGA-CC-5260-01 | exon_skip_346778 | 219423221 | 219423400 | 219423315 | 219423315 | Frame_Shift_Del | T | - | p.K21fs |
| LIHC | TCGA-CC-5260-01 | exon_skip_346780 | 219423221 | 219423440 | 219423315 | 219423315 | Frame_Shift_Del | T | - | p.K21fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_346778 | 219423221 | 219423400 | 219423323 | 219423323 | Frame_Shift_Del | C | - | p.G18fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_346780 | 219423221 | 219423440 | 219423323 | 219423323 | Frame_Shift_Del | C | - | p.G18fs |
| LIHC | TCGA-DD-AAW2-01 | exon_skip_346763 | 219330733 | 219330899 | 219330793 | 219330794 | Frame_Shift_Ins | - | A | p.M802fs |
| ESCA | TCGA-Z6-A8JE-01 | exon_skip_346766 | 219344373 | 219344438 | 219344376 | 219344376 | Nonsense_Mutation | G | T | p.S633X |
| LIHC | TCGA-2Y-A9H2-01 | exon_skip_346769 | 219374702 | 219374863 | 219374706 | 219374706 | Nonsense_Mutation | G | A | p.Q341X |
| PAAD | TCGA-IB-7651-01 | exon_skip_346769 | 219374702 | 219374863 | 219374752 | 219374752 | Nonsense_Mutation | C | T | p.W325* |
| PAAD | TCGA-IB-7651-01 | exon_skip_346769 | 219374702 | 219374863 | 219374752 | 219374752 | Nonsense_Mutation | C | T | p.W325X |
| BLCA | TCGA-XF-A9SZ-01 | exon_skip_346775 | 219414532 | 219414632 | 219414542 | 219414542 | Nonsense_Mutation | G | C | p.S140* |
| CESC | TCGA-C5-A1BM-01 | exon_skip_346760 | 219321815 | 219321884 | 219321885 | 219321885 | Splice_Site | C | T | e21-1 |
| CESC | TCGA-IR-A3LH-01 | exon_skip_346763 | 219330733 | 219330899 | 219330900 | 219330900 | Splice_Site | C | A | e18-1 |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 219330733 | 219330899 | 219330793 | 219330794 | Frame_Shift_Del | CA | - | p.M802fs |
| RCK8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 219330733 | 219330899 | 219330819 | 219330819 | Frame_Shift_Del | C | - | p.V794fs |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 219330733 | 219330899 | 219330796 | 219330797 | Frame_Shift_Ins | - | CG | p.D801fs |
| C2BBE1_LARGE_INTESTINE | 219320303 | 219320441 | 219320317 | 219320317 | Missense_Mutation | G | T | p.F946L |
| CACO2_LARGE_INTESTINE | 219320303 | 219320441 | 219320317 | 219320317 | Missense_Mutation | G | T | p.F946L |
| HEC1A_ENDOMETRIUM | 219321815 | 219321884 | 219321844 | 219321844 | Missense_Mutation | A | T | p.V895D |
| SNU719_STOMACH | 219324513 | 219324628 | 219324529 | 219324529 | Missense_Mutation | A | C | p.L876R |
| UACC62_SKIN | 219324513 | 219324628 | 219324561 | 219324561 | Missense_Mutation | A | T | p.D865E |
| 8305C_THYROID | 219328029 | 219328089 | 219328061 | 219328061 | Missense_Mutation | T | C | p.D832G |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 219344373 | 219344438 | 219344383 | 219344383 | Missense_Mutation | T | C | p.T631A |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 219344373 | 219344438 | 219344418 | 219344418 | Missense_Mutation | G | C | p.S619C |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 219344373 | 219344438 | 219344424 | 219344424 | Missense_Mutation | T | C | p.K617R |
| NO11_CENTRAL_NERVOUS_SYSTEM | 219353027 | 219353144 | 219353085 | 219353085 | Missense_Mutation | C | T | p.R511H |
| MFE296_ENDOMETRIUM | 219353027 | 219353144 | 219353086 | 219353086 | Missense_Mutation | G | C | p.R511G |
| NB6_AUTONOMIC_GANGLIA | 219374702 | 219374863 | 219374738 | 219374738 | Missense_Mutation | A | C | p.V330G |
| NCIBL2126_MATCHED_NORMAL_TISSUE | 219374702 | 219374863 | 219374738 | 219374738 | Missense_Mutation | A | C | p.V330G |
| NCIH2126_LUNG | 219374702 | 219374863 | 219374738 | 219374738 | Missense_Mutation | A | C | p.V330G |
| SAOS2_BONE | 219374702 | 219374863 | 219374762 | 219374762 | Missense_Mutation | T | A | p.Y322F |
| KYSE270_OESOPHAGUS | 219399332 | 219399429 | 219399347 | 219399347 | Missense_Mutation | C | G | p.E255Q |
| NCIH1299_LUNG | 219399332 | 219399429 | 219399364 | 219399364 | Missense_Mutation | C | T | p.S249N |
| RPMI8402_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 219414532 | 219414632 | 219414548 | 219414548 | Missense_Mutation | G | A | p.S138F |
| NCIH1734_LUNG | 219414532 | 219414632 | 219414614 | 219414614 | Missense_Mutation | C | T | p.G116E |
| HT115_LARGE_INTESTINE | 219423221 | 219423440 | 219423256 | 219423256 | Missense_Mutation | G | T | p.H41N |
| HT115_LARGE_INTESTINE | 219423221 | 219423400 | 219423256 | 219423256 | Missense_Mutation | G | T | p.H41N |
| ISTMEL1_SKIN | 219423221 | 219423440 | 219423351 | 219423351 | Missense_Mutation | G | A | p.P9L |
| ISTMEL1_SKIN | 219423221 | 219423400 | 219423351 | 219423351 | Missense_Mutation | G | A | p.P9L |
| MCF7_BREAST | 219321815 | 219321884 | 219321881 | 219321881 | Nonsense_Mutation | C | A | p.G883* |
| EN_ENDOMETRIUM | 219394679 | 219394763 | 219394749 | 219394749 | Nonsense_Mutation | G | A | p.Q265* |
| KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 219414532 | 219414632 | 219414555 | 219414555 | Nonsense_Mutation | G | A | p.Q136* |
| HEC1A_ENDOMETRIUM | 219423221 | 219423440 | 219423340 | 219423340 | Nonsense_Mutation | G | A | p.R13* |
| HEC1A_ENDOMETRIUM | 219423221 | 219423400 | 219423340 | 219423340 | Nonsense_Mutation | G | A | p.R13* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for USP37 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for USP37 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for USP37 |
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RelatedDrugs for USP37 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for USP37 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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