ExonSkipDB Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
leaf

Gene summary

leaf

Gene structures and expression levels

leaf

Exon skipping events with PSIs in TCGA

leaf

Exon skipping events with PSIs in GTEx

leaf

Open reading frame (ORF) annotation in the exon skipping event

leaf

Exon skipping events in the canonical protein sequence

leaf

SNVs in the skipped exons with depth of coverage

leaf

Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

leaf

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

leaf

Related drugs with this gene

leaf

Related diseases with this gene

Gene summary for PRPSAP2

check button Gene summary
Gene informationGene symbol

PRPSAP2

Gene ID

5636

Gene namephosphoribosyl pyrophosphate synthetase associated protein 2
SynonymsPAP41
Cytomap

17p11.2

Type of geneprotein-coding
Descriptionphosphoribosyl pyrophosphate synthase-associated protein 241 kDa phosphoribosypyrophosphate synthetase-associated proteinPRPP synthase-associated protein 2
Modification date20180523
UniProtAcc

O60256

ContextPubMed: PRPSAP2 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

Top

Exon skipping events across known transcript of Ensembl for PRPSAP2 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

Top

Gene isoform structures and expression levels for PRPSAP2

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


Top

Exon skipping events with PSIs in TCGA for PRPSAP2

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENSG00000141127.10ENST00000574522.1,ENST00000487101.1
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000573253.1,ENST00000573432.1,ENST00000419071.2,ENST00000492129.1
exon_skip_1496821718759654:18759789:18762652:18762788:18768781:1876887718762652:18762788ENSG00000141127.10ENST00000570450.1
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000574522.1,ENST00000487101.1
exon_skip_1496901718761498:18761574:18762652:18762788:18768781:1876887718762652:18762788ENSG00000141127.10ENST00000419284.2
exon_skip_1496931718761443:18761574:18768180:18768254:18768781:1876887718768180:18768254ENSG00000141127.10ENST00000575228.1
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000268835.2,ENST00000478622.2,ENST00000455992.2,ENST00000571907.1
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000576355.1
exon_skip_1496991718762652:18762788:18763878:18764004:18768781:1876887718763878:18764004ENSG00000141127.10ENST00000575102.1
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000419284.2,ENST00000570450.1
exon_skip_1497021718769114:18769265:18770569:18770647:18775895:1877594118770569:18770647ENSG00000141127.10ENST00000573253.1,ENST00000571907.1
exon_skip_1497041718769114:18769265:18770594:18770647:18775895:1877594118770594:18770647ENSG00000141127.10ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENSG00000141127.10ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENSG00000141127.10ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1
exon_skip_1497131718781010:18781183:18785880:18785996:18793134:1879319018785880:18785996ENSG00000141127.10ENST00000542013.1,ENST00000395656.2,ENST00000432893.2,ENST00000268835.2,ENST00000412418.1,ENST00000419071.2,ENST00000422237.1,ENST00000487101.1,ENST00000536323.1,ENST00000414602.1,ENST00000492129.1
exon_skip_1497161718793134:18793190:18814415:18814564:18827226:1882729718814415:18814564ENSG00000141127.10ENST00000542013.1,ENST00000395656.2,ENST00000432893.2,ENST00000268835.2,ENST00000412418.1,ENST00000419071.2,ENST00000455992.2,ENST00000536323.1,ENST00000492129.1
exon_skip_1497211718814466:18814564:18820744:18820849:18827226:1882729718820744:18820849ENSG00000141127.10ENST00000574451.1
exon_skip_1497261718814466:18814564:18827226:18827297:18832123:1883227018827226:18827297ENSG00000141127.10ENST00000395656.2,ENST00000268835.2,ENST00000460724.1,ENST00000419071.2,ENST00000536323.1,ENST00000492129.1
exon_skip_1497311718827226:18827297:18832123:18832270:18833852:1883404718832123:18832270ENSG00000141127.10ENST00000395656.2,ENST00000268835.2,ENST00000574451.1,ENST00000419071.2,ENST00000536323.1,ENST00000492129.1

check button PSI values of skipped exons in TCGA.
psi tcga

Top

Exon skipping events with PSIs in GTEx for PRPSAP2

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENSG00000141127.10ENST00000574522.1,ENST00000487101.1
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000573432.1,ENST00000492129.1,ENST00000419071.2,ENST00000573253.1
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000574522.1,ENST00000487101.1
exon_skip_1496901718761498:18761574:18762652:18762788:18768781:1876887718762652:18762788ENSG00000141127.10ENST00000419284.2
exon_skip_1496931718761443:18761574:18768180:18768254:18768781:1876887718768180:18768254ENSG00000141127.10ENST00000575228.1
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000571907.1,ENST00000268835.2,ENST00000478622.2,ENST00000455992.2
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000576355.1
exon_skip_1496991718762652:18762788:18763878:18764004:18768781:1876887718763878:18764004ENSG00000141127.10ENST00000575102.1
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENSG00000141127.10ENST00000570450.1,ENST00000419284.2
exon_skip_1497021718769114:18769265:18770569:18770647:18775895:1877594118770569:18770647ENSG00000141127.10ENST00000573253.1,ENST00000571907.1
exon_skip_1497041718769114:18769265:18770594:18770647:18775895:1877594118770594:18770647ENSG00000141127.10ENST00000441887.1,ENST00000432893.2,ENST00000414602.1,ENST00000574522.1,ENST00000570450.1,ENST00000419284.2,ENST00000268835.2,ENST00000412418.1,ENST00000455992.2,ENST00000576355.1,ENST00000422237.1,ENST00000542013.1
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENSG00000141127.10ENST00000573432.1,ENST00000492129.1,ENST00000487101.1,ENST00000395656.2,ENST00000478622.2,ENST00000536323.1
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENSG00000141127.10ENST00000441887.1,ENST00000432893.2,ENST00000414602.1,ENST00000574522.1,ENST00000570450.1,ENST00000573253.1,ENST00000419284.2,ENST00000268835.2,ENST00000412418.1,ENST00000455992.2,ENST00000576355.1,ENST00000422237.1,ENST00000542013.1
exon_skip_1497131718781010:18781183:18785880:18785996:18793134:1879319018785880:18785996ENSG00000141127.10ENST00000432893.2,ENST00000414602.1,ENST00000492129.1,ENST00000419071.2,ENST00000487101.1,ENST00000268835.2,ENST00000412418.1,ENST00000395656.2,ENST00000536323.1,ENST00000422237.1,ENST00000542013.1
exon_skip_1497161718793134:18793190:18814415:18814564:18827226:1882729718814415:18814564ENSG00000141127.10ENST00000432893.2,ENST00000492129.1,ENST00000419071.2,ENST00000268835.2,ENST00000412418.1,ENST00000395656.2,ENST00000536323.1,ENST00000455992.2,ENST00000542013.1
exon_skip_1497211718814466:18814564:18820744:18820849:18827226:1882729718820744:18820849ENSG00000141127.10ENST00000574451.1
exon_skip_1497261718814466:18814564:18827226:18827297:18832123:1883227018827226:18827297ENSG00000141127.10ENST00000492129.1,ENST00000419071.2,ENST00000268835.2,ENST00000395656.2,ENST00000536323.1,ENST00000460724.1
exon_skip_1497271718814466:18814564:18827226:18827297:18833852:1883404718827226:18827297ENSG00000141127.10ENST00000542013.1
exon_skip_1497311718827226:18827297:18832123:18832270:18833852:1883404718832123:18832270ENSG00000141127.10ENST00000492129.1,ENST00000419071.2,ENST00000268835.2,ENST00000395656.2,ENST00000536323.1,ENST00000574451.1

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

Top

Open reading frame (ORF) annotation in the exon skipping event for PRPSAP2

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000026883518768781187688775UTR-5UTR
ENST000002688351877059418770647Frame-shift
ENST000002688351877589518775962Frame-shift
ENST000002688351878588018785996Frame-shift
ENST000002688351881441518814564Frame-shift
ENST000002688351882722618827297Frame-shift
ENST000002688351883212318832270In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000026883518768781187688775UTR-5UTR
ENST000002688351877059418770647Frame-shift
ENST000002688351877589518775962Frame-shift
ENST000002688351878588018785996Frame-shift
ENST000002688351881441518814564Frame-shift
ENST000002688351882722618827297Frame-shift
ENST000002688351883212318832270In-frame

Top

Infer the effects of exon skipping event on protein functional features for PRPSAP2

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000002688351927369188321231883227010881234268317

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000002688351927369188321231883227010881234268317

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O60256268317269317Alternative sequenceID=VSP_046462;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
O60256268317263272Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O60256268317292300Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O60256268317317324Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O602562683171369ChainID=PRO_0000141082;Note=Phosphoribosyl pyrophosphate synthase-associated protein 2
O60256268317276287HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O60256268317306312HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O60256268317269317Alternative sequenceID=VSP_046462;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
O60256268317263272Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O60256268317292300Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O60256268317317324Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O602562683171369ChainID=PRO_0000141082;Note=Phosphoribosyl pyrophosphate synthase-associated protein 2
O60256268317276287HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4
O60256268317306312HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2JI4


Top

SNVs in the skipped exons for PRPSAP2

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A3A0-01exon_skip_149731
18832124188322701883223618832236Frame_Shift_DelC-p.A306fs
STADTCGA-HJ-7597-01exon_skip_149731
18832124188322701883223618832236Frame_Shift_DelC-p.A306fs
LUADTCGA-44-2656-01exon_skip_149731
18832124188322701883223518832236Frame_Shift_Ins-Cp.A306fs
UCECTCGA-AP-A0LD-01exon_skip_149731
18832124188322701883223518832236Frame_Shift_Ins-Cp.A306fs
UCECTCGA-BG-A0M9-01exon_skip_149731
18832124188322701883223518832236Frame_Shift_Ins-Cp.A306fs
BRCATCGA-AO-A125-01exon_skip_149713
18785881187859961878597918785979Nonsense_MutationCTp.Q171*

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
SNU175_LARGE_INTESTINE18775896187759621877592018775920Missense_MutationCAp.S66Y
HEC251_ENDOMETRIUM18775896187759621877595918775959Missense_MutationCTp.S79L
SNU1040_LARGE_INTESTINE18785881187859961878594418785944Missense_MutationCAp.P159H
SKUT1_SOFT_TISSUE18814416188145641881444218814442Missense_MutationGAp.R204H
D336MG_CENTRAL_NERVOUS_SYSTEM18814416188145641881444818814448Missense_MutationGAp.G206E
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE18832124188322701883213918832139Missense_MutationGAp.D274N
L428_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE18832124188322701883224518832245Missense_MutationGAp.R309Q

Top

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PRPSAP2

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1GBMrs4393623chr17:18775900A/G3.96e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1COADrs4393623chr17:18775900A/G5.70e-05
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1HNSCrs4393623chr17:18775900A/G9.09e-08
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1KIRPrs4393623chr17:18775900A/G1.28e-03
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1LGGrs4393623chr17:18775900A/G5.75e-14
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1LGGrs4393623chr17:18775900A/G1.32e-11
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1LGGrs4393623chr17:18775900A/G4.21e-11
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1KIRCrs4393623chr17:18775900A/G1.55e-06
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1KIRCrs4393623chr17:18775900A/G2.70e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1KIRCrs4393623chr17:18775900A/G9.15e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1MESOrs4393623chr17:18775900A/G1.53e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1PCPGrs4393623chr17:18775900A/G1.52e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1PAADrs4393623chr17:18775900A/G6.69e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1PRADrs4393623chr17:18775900A/G7.21e-06
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1PRADrs4393623chr17:18775900A/G5.55e-05
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1SARCrs4393623chr17:18775900A/G4.67e-06
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1TGCTrs4393623chr17:18775900A/G3.04e-05
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1THCArs4393623chr17:18775900A/G5.81e-10
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1THCArs4393623chr17:18775900A/G5.27e-06
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1THCArs4393623chr17:18775900A/G1.69e-04
exon_skip_1497121718770594:18770647:18775895:18775962:18781010:1878105118775895:18775962ENST00000573253.1,ENST00000542013.1,ENST00000441887.1,ENST00000432893.2,ENST00000268835.2,ENST00000419284.2,ENST00000576355.1,ENST00000412418.1,ENST00000570450.1,ENST00000574522.1,ENST00000422237.1,ENST00000455992.2,ENST00000414602.1UCECrs4393623chr17:18775900A/G7.92e-07
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1GBMrs4393623chr17:18775900A/G3.96e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1COADrs4393623chr17:18775900A/G5.70e-05
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1HNSCrs4393623chr17:18775900A/G9.09e-08
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1KIRPrs4393623chr17:18775900A/G1.28e-03
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1LGGrs4393623chr17:18775900A/G5.75e-14
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1LGGrs4393623chr17:18775900A/G1.32e-11
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1LGGrs4393623chr17:18775900A/G4.21e-11
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1KIRCrs4393623chr17:18775900A/G1.55e-06
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1KIRCrs4393623chr17:18775900A/G2.70e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1KIRCrs4393623chr17:18775900A/G9.15e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1MESOrs4393623chr17:18775900A/G1.53e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1PCPGrs4393623chr17:18775900A/G1.52e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1PAADrs4393623chr17:18775900A/G6.69e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1PRADrs4393623chr17:18775900A/G7.21e-06
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1PRADrs4393623chr17:18775900A/G5.55e-05
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1SARCrs4393623chr17:18775900A/G4.67e-06
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1TGCTrs4393623chr17:18775900A/G3.04e-05
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1THCArs4393623chr17:18775900A/G5.81e-10
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1THCArs4393623chr17:18775900A/G5.27e-06
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1THCArs4393623chr17:18775900A/G1.69e-04
exon_skip_1497061718769114:18769265:18775895:18775962:18781010:1878105118775895:18775962ENST00000395656.2,ENST00000573432.1,ENST00000478622.2,ENST00000487101.1,ENST00000536323.1,ENST00000492129.1UCECrs4393623chr17:18775900A/G7.92e-07
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENST00000573253.1,ENST00000573432.1,ENST00000419071.2,ENST00000492129.1HNSCrs2305061chr17:18768870C/T3.14e-04
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENST00000573253.1,ENST00000573432.1,ENST00000419071.2,ENST00000492129.1LGGrs2305061chr17:18768870C/T1.42e-04
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENST00000573253.1,ENST00000573432.1,ENST00000419071.2,ENST00000492129.1LGGrs2305061chr17:18768870C/T6.42e-04
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENST00000573253.1,ENST00000573432.1,ENST00000419071.2,ENST00000492129.1LGGrs2305061chr17:18768870C/T1.34e-03
exon_skip_1496781718759693:18759742:18768781:18768877:18769114:1876921318768781:18768877ENST00000573253.1,ENST00000573432.1,ENST00000419071.2,ENST00000492129.1PRADrs2305061chr17:18768870C/T8.17e-05
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1COADrs8066636chr17:18761109G/A1.18e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1BLCArs8066385chr17:18761133C/T1.01e-05
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1HNSCrs8066636chr17:18761109G/A4.63e-07
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1KIRPrs8066636chr17:18761109G/A6.44e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1KIRPrs8066636chr17:18761109G/A9.55e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LGGrs8066636chr17:18761109G/A3.79e-15
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LGGrs8066636chr17:18761109G/A1.67e-12
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LGGrs8066636chr17:18761109G/A2.16e-11
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LGGrs8066385chr17:18761133C/T2.02e-06
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LGGrs8066385chr17:18761133C/T1.14e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LGGrs8066385chr17:18761133C/T7.21e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1KIRCrs8066636chr17:18761109G/A6.41e-07
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1KIRCrs8066636chr17:18761109G/A2.13e-05
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1KIRCrs8066385chr17:18761133C/T1.10e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LUADrs8066636chr17:18761109G/A1.42e-06
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LUADrs8066636chr17:18761109G/A6.29e-05
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1LUADrs8066636chr17:18761109G/A2.41e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1PCPGrs8066636chr17:18761109G/A7.09e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1PAADrs8066636chr17:18761109G/A5.18e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1PRADrs8066636chr17:18761109G/A5.18e-06
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1PRADrs8066636chr17:18761109G/A9.64e-05
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1PRADrs8066385chr17:18761133C/T1.11e-03
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1THYMrs8066636chr17:18761109G/A3.03e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1THYMrs8066636chr17:18761109G/A6.61e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1TGCTrs8066636chr17:18761109G/A6.30e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1THCArs8066636chr17:18761109G/A9.68e-11
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1THCArs8066636chr17:18761109G/A7.76e-06
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1THCArs8066636chr17:18761109G/A1.18e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1THCArs8066385chr17:18761133C/T4.95e-04
exon_skip_1496741718759693:18759742:18761096:18761166:18768781:1876887718761096:18761166ENST00000574522.1,ENST00000487101.1UCECrs8066636chr17:18761109G/A8.44e-06
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENST00000576355.1HNSCrs2305061chr17:18768870C/T3.14e-04
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENST00000576355.1LGGrs2305061chr17:18768870C/T1.42e-04
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENST00000576355.1LGGrs2305061chr17:18768870C/T6.42e-04
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENST00000576355.1LGGrs2305061chr17:18768870C/T1.34e-03
exon_skip_1496981718761754:18761875:18768781:18768877:18769114:1876921318768781:18768877ENST00000576355.1PRADrs2305061chr17:18768870C/T8.17e-05
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENST00000268835.2,ENST00000478622.2,ENST00000455992.2,ENST00000571907.1HNSCrs2305061chr17:18768870C/T3.14e-04
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENST00000268835.2,ENST00000478622.2,ENST00000455992.2,ENST00000571907.1LGGrs2305061chr17:18768870C/T1.42e-04
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENST00000268835.2,ENST00000478622.2,ENST00000455992.2,ENST00000571907.1LGGrs2305061chr17:18768870C/T6.42e-04
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENST00000268835.2,ENST00000478622.2,ENST00000455992.2,ENST00000571907.1LGGrs2305061chr17:18768870C/T1.34e-03
exon_skip_1496941718761498:18761574:18768781:18768877:18769114:1876921318768781:18768877ENST00000268835.2,ENST00000478622.2,ENST00000455992.2,ENST00000571907.1PRADrs2305061chr17:18768870C/T8.17e-05
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENST00000419284.2,ENST00000570450.1HNSCrs2305061chr17:18768870C/T3.14e-04
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENST00000419284.2,ENST00000570450.1LGGrs2305061chr17:18768870C/T1.42e-04
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENST00000419284.2,ENST00000570450.1LGGrs2305061chr17:18768870C/T6.42e-04
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENST00000419284.2,ENST00000570450.1LGGrs2305061chr17:18768870C/T1.34e-03
exon_skip_1497011718762652:18762788:18768781:18768877:18769114:1876921318768781:18768877ENST00000419284.2,ENST00000570450.1PRADrs2305061chr17:18768870C/T8.17e-05
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENST00000574522.1,ENST00000487101.1HNSCrs2305061chr17:18768870C/T3.14e-04
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENST00000574522.1,ENST00000487101.1LGGrs2305061chr17:18768870C/T1.42e-04
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENST00000574522.1,ENST00000487101.1LGGrs2305061chr17:18768870C/T6.42e-04
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENST00000574522.1,ENST00000487101.1LGGrs2305061chr17:18768870C/T1.34e-03
exon_skip_1496881718761096:18761166:18768781:18768877:18769114:1876921318768781:18768877ENST00000574522.1,ENST00000487101.1PRADrs2305061chr17:18768870C/T8.17e-05

Top

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PRPSAP2


Top

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PRPSAP2


Top

RelatedDrugs for PRPSAP2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for PRPSAP2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource