ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for PARPBP

Gene summary

Gene information	Gene symbol	PARPBP
	Gene ID	55010
	Gene name	PARP1 binding protein
	Synonyms	AROM\|C12orf48\|PARI
	Cytomap	12q23.2
	Type of gene	protein-coding
	Description	PCNA-interacting partner
	Modification date	20180519
	UniProtAcc	Q9NWS1
	Context	PubMed: PARPBP [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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Exon skipping events across known transcript of Ensembl for PARPBP from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Gene isoform structures and expression levels for PARPBP

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

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Exon skipping events with PSIs in TCGA for PARPBP

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENSG00000185480.7	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENSG00000185480.7	ENST00000392911.2
exon_skip_86315	12	102517765:102517819:102530914:102531022:102542007:102542241	102530914:102531022	ENSG00000185480.7	ENST00000327680.2
exon_skip_86317	12	102517765:102517819:102542007:102542241:102547646:102547754	102542007:102542241	ENSG00000185480.7	ENST00000412715.2,ENST00000378128.3,ENST00000358383.5,ENST00000541668.1,ENST00000417507.2
exon_skip_86320	12	102517765:102517819:102542012:102542241:102547646:102547754	102542012:102542241	ENSG00000185480.7	ENST00000392911.2
exon_skip_86328	12	102517765:102517819:102547646:102547767:102559506:102559661	102547646:102547767	ENSG00000185480.7	ENST00000457614.2
exon_skip_86329	12	102517765:102517819:102558215:102558386:102559506:102559661	102558215:102558386	ENSG00000185480.7	ENST00000543784.1
exon_skip_86334	12	102542012:102542241:102544041:102544149:102545347:102545578	102544041:102544149	ENSG00000185480.7	ENST00000392909.3
exon_skip_86337	12	102542012:102542241:102545347:102545578:102547646:102547754	102545347:102545578	ENSG00000185480.7	ENST00000541394.1
exon_skip_86339	12	102542012:102542241:102547646:102547754:102558215:102558386	102547646:102547754	ENSG00000185480.7	ENST00000327680.2,ENST00000412715.2,ENST00000378128.3,ENST00000358383.5,ENST00000392911.2,ENST00000417507.2
exon_skip_86346	12	102547646:102547754:102558215:102558386:102559506:102559661	102558215:102558386	ENSG00000185480.7	ENST00000327680.2,ENST00000412715.2,ENST00000378128.3,ENST00000358383.5,ENST00000541394.1,ENST00000392911.2,ENST00000417507.2
exon_skip_86352	12	102559506:102559661:102569260:102569444:102572369:102572548	102569260:102569444	ENSG00000185480.7	ENST00000457614.2,ENST00000327680.2,ENST00000358383.5,ENST00000541394.1,ENST00000392911.2
exon_skip_86361	12	102559506:102559661:102576326:102576405:102589728:102589865	102576326:102576405	ENSG00000185480.7	ENST00000417507.2
exon_skip_86364	12	102569260:102569444:102572369:102572548:102576326:102576405	102572369:102572548	ENSG00000185480.7	ENST00000457614.2,ENST00000327680.2,ENST00000358383.5,ENST00000541394.1,ENST00000392911.2
exon_skip_86370	12	102572369:102572548:102576326:102576405:102589089:102589225	102576326:102576405	ENSG00000185480.7	ENST00000457614.2,ENST00000327680.2,ENST00000358383.5,ENST00000541394.1,ENST00000392911.2
exon_skip_86373	12	102576326:102576405:102589089:102589225:102589728:102589865	102589089:102589225	ENSG00000185480.7	ENST00000457614.2,ENST00000327680.2,ENST00000358383.5,ENST00000541394.1,ENST00000392911.2

PSI values of skipped exons in TCGA.

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Exon skipping events with PSIs in GTEx for PARPBP

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENSG00000185480.7	ENST00000541394.1,ENST00000392909.3,ENST00000537257.1,ENST00000358383.5
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENSG00000185480.7	ENST00000392911.2
exon_skip_86315	12	102517765:102517819:102530914:102531022:102542007:102542241	102530914:102531022	ENSG00000185480.7	ENST00000327680.2
exon_skip_86317	12	102517765:102517819:102542007:102542241:102547646:102547754	102542007:102542241	ENSG00000185480.7	ENST00000378128.3,ENST00000358383.5,ENST00000541668.1,ENST00000417507.2,ENST00000412715.2
exon_skip_86320	12	102517765:102517819:102542012:102542241:102547646:102547754	102542012:102542241	ENSG00000185480.7	ENST00000392911.2
exon_skip_86328	12	102517765:102517819:102547646:102547767:102559506:102559661	102547646:102547767	ENSG00000185480.7	ENST00000457614.2
exon_skip_86329	12	102517765:102517819:102558215:102558386:102559506:102559661	102558215:102558386	ENSG00000185480.7	ENST00000543784.1
exon_skip_86334	12	102542012:102542241:102544041:102544149:102545347:102545578	102544041:102544149	ENSG00000185480.7	ENST00000392909.3
exon_skip_86337	12	102542012:102542241:102545347:102545578:102547646:102547754	102545347:102545578	ENSG00000185480.7	ENST00000541394.1
exon_skip_86339	12	102542012:102542241:102547646:102547754:102558215:102558386	102547646:102547754	ENSG00000185480.7	ENST00000378128.3,ENST00000327680.2,ENST00000358383.5,ENST00000392911.2,ENST00000417507.2,ENST00000412715.2
exon_skip_86346	12	102547646:102547754:102558215:102558386:102559506:102559661	102558215:102558386	ENSG00000185480.7	ENST00000378128.3,ENST00000327680.2,ENST00000541394.1,ENST00000358383.5,ENST00000392911.2,ENST00000417507.2,ENST00000412715.2
exon_skip_86352	12	102559506:102559661:102569260:102569444:102572369:102572548	102569260:102569444	ENSG00000185480.7	ENST00000327680.2,ENST00000541394.1,ENST00000358383.5,ENST00000392911.2,ENST00000457614.2
exon_skip_86361	12	102559506:102559661:102576326:102576405:102589728:102589865	102576326:102576405	ENSG00000185480.7	ENST00000417507.2
exon_skip_86364	12	102569260:102569444:102572369:102572548:102576326:102576405	102572369:102572548	ENSG00000185480.7	ENST00000327680.2,ENST00000541394.1,ENST00000358383.5,ENST00000392911.2,ENST00000457614.2
exon_skip_86370	12	102572369:102572548:102576326:102576405:102589089:102589225	102576326:102576405	ENSG00000185480.7	ENST00000327680.2,ENST00000541394.1,ENST00000358383.5,ENST00000392911.2,ENST00000457614.2
exon_skip_86373	12	102576326:102576405:102589089:102589225:102589728:102589865	102589089:102589225	ENSG00000185480.7	ENST00000327680.2,ENST00000541394.1,ENST00000358383.5,ENST00000392911.2,ENST00000457614.2

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for PARPBP

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000327680	102530914	102531022	5UTR-5UTR
ENST00000327680	102569260	102569444	Frame-shift
ENST00000327680	102572369	102572548	Frame-shift
ENST00000327680	102576326	102576405	Frame-shift
ENST00000327680	102589089	102589225	Frame-shift
ENST00000327680	102547646	102547754	In-frame
ENST00000327680	102558215	102558386	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000327680	102530914	102531022	5UTR-5UTR
ENST00000327680	102569260	102569444	Frame-shift
ENST00000327680	102572369	102572548	Frame-shift
ENST00000327680	102576326	102576405	Frame-shift
ENST00000327680	102589089	102589225	Frame-shift
ENST00000327680	102547646	102547754	In-frame
ENST00000327680	102558215	102558386	In-frame

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Infer the effects of exon skipping event on protein functional features for PARPBP

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000327680	3206	579	102547646	102547754	608	715	48	84
ENST00000327680	3206	579	102558215	102558386	716	886	84	141

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000327680	3206	579	102547646	102547754	608	715	48	84
ENST00000327680	3206	579	102558215	102558386	716	886	84	141

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.

Start of exon skipping (AA)

End of exon skipping (AA)

Protein feature start (AA)

Protein feature end (AA)

Category of protein feature

Description of feature

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.

Start of exon skipping (AA)

End of exon skipping (AA)

Protein feature start (AA)

Protein feature end (AA)

Category of protein feature

Description of feature

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SNVs in the skipped exons for PARPBP

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
UCEC	TCGA-BG-A0LX-01	exon_skip_86339	102547647	102547754	102547674	102547674	Frame_Shift_Del	A	-	p.K216fs
UCEC	TCGA-BG-A0LX-01	exon_skip_86339	102547647	102547754	102547674	102547674	Frame_Shift_Del	A	-	p.K58fs
UCEC	TCGA-BG-A0LX-01	exon_skip_86328	102547647	102547767	102547674	102547674	Frame_Shift_Del	A	-	p.K216fs
UCEC	TCGA-BG-A0LX-01	exon_skip_86328	102547647	102547767	102547674	102547674	Frame_Shift_Del	A	-	p.K58fs
LIHC	TCGA-DD-A3A0-01	exon_skip_86364	102572370	102572548	102572523	102572523	Frame_Shift_Del	G	-	p.G306fs
COAD	TCGA-A6-6142-01	exon_skip_86370 exon_skip_86361	102576327	102576405	102576394	102576394	Frame_Shift_Del	A	-	p.E417fs
LIHC	TCGA-DD-A39Y-01	exon_skip_86370 exon_skip_86361	102576327	102576405	102576394	102576394	Frame_Shift_Del	A	-	p.K338fs
LIHC	TCGA-G3-A3CJ-01	exon_skip_86370 exon_skip_86361	102576327	102576405	102576394	102576394	Frame_Shift_Del	A	-	p.K338fs
CESC	TCGA-IR-A3LH-01	exon_skip_86346 exon_skip_86329	102558216	102558386	102558365	102558366	Frame_Shift_Ins	-	A	p.Q216fs
ESCA	TCGA-LN-A49L-01	exon_skip_86346 exon_skip_86329	102558216	102558386	102558360	102558360	Nonsense_Mutation	C	T	p.R133*
ESCA	TCGA-LN-A49L-01	exon_skip_86346 exon_skip_86329	102558216	102558386	102558360	102558360	Nonsense_Mutation	C	T	p.R214*
ESCA	TCGA-LN-A49L-01	exon_skip_86346 exon_skip_86329	102558216	102558386	102558360	102558360	Nonsense_Mutation	C	T	p.R214X
THYM	TCGA-XU-A92W-01	exon_skip_86339	102547647	102547754	102547755	102547755	Splice_Site	G	T	.

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons

Mutation description

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
NCIH1793_LUNG	102569261	102569444	102569329	102569330	Frame_Shift_Ins	-	T	p.PF297fs
SNU1040_LARGE_INTESTINE	102576327	102576405	102576393	102576394	Frame_Shift_Ins	-	A	p.K418fs
HT115_LARGE_INTESTINE	102517664	102517819	102517716	102517716	Missense_Mutation	G	A	p.R17Q
JHUEM7_ENDOMETRIUM	102517664	102517819	102517716	102517716	Missense_Mutation	G	A	p.R17Q
NCIH441_LUNG	102542008	102542241	102542133	102542133	Missense_Mutation	G	T	p.K93N
NCIH441_LUNG	102542013	102542241	102542133	102542133	Missense_Mutation	G	T	p.K93N
MYM12_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	102542008	102542241	102542194	102542194	Missense_Mutation	T	C	p.C114R
MYM12_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	102542013	102542241	102542194	102542194	Missense_Mutation	T	C	p.C114R
PC9_LUNG	102547647	102547754	102547650	102547650	Missense_Mutation	C	A	p.Q131K
PC9_LUNG	102547647	102547767	102547650	102547650	Missense_Mutation	C	A	p.Q131K
2313287_STOMACH	102547647	102547754	102547730	102547730	Missense_Mutation	T	A	p.S157R
2313287_STOMACH	102547647	102547767	102547730	102547730	Missense_Mutation	T	A	p.S157R
JHUEM7_ENDOMETRIUM	102558216	102558386	102558235	102558235	Missense_Mutation	A	C	p.K172T
SKMES1_LUNG	102558216	102558386	102558324	102558324	Missense_Mutation	G	A	p.G202R
RKN_SOFT_TISSUE	102569261	102569444	102569271	102569271	Missense_Mutation	G	T	p.G278C
HEC108_ENDOMETRIUM	102569261	102569444	102569302	102569302	Missense_Mutation	T	C	p.L288P
SNU1040_LARGE_INTESTINE	102572370	102572548	102572434	102572434	Missense_Mutation	T	C	p.L357S
HCC2998_LARGE_INTESTINE	102572370	102572548	102572448	102572448	Missense_Mutation	G	A	p.E362K
PEDS005TPFAD_KIDNEY	102576327	102576405	102576350	102576350	Missense_Mutation	C	T	p.S403L
CJM_SKIN	102576327	102576405	102576350	102576350	Missense_Mutation	C	G	p.S403W
RH1_SOFT_TISSUE	102589090	102589225	102589152	102589152	Missense_Mutation	C	A	p.S442R
DJM1_SKIN	102589090	102589225	102589215	102589215	Missense_Mutation	T	G	p.N463K
OVTOKO_OVARY	102517664	102517819	102517682	102517682	Nonsense_Mutation	C	T	p.Q6*
KMH2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	102572370	102572548	102572491	102572491	Nonsense_Mutation	T	G	p.L376*
HEPG2_LIVER	102569261	102569444	102569443	102569443	Splice_Site	G	A	p.R335Q
C3A_LIVER	102569261	102569444	102569443	102569443	Splice_Site	G	A	p.R335Q

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PARPBP

sQTL information located at the skipped exons.

Exon skip ID	Chromosome	Three exons	Skippped exon	ENST	Cancer type	SNP id	Location	DNA change (ref/var)	P-value
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	BLCA	rs2036772	chr12:102517753	T/C	5.25e-04
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	BLCA	rs2036772	chr12:102517753	T/C	9.55e-04
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	HNSC	rs2036771	chr12:102517804	A/G	2.12e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	HNSC	rs2036771	chr12:102517804	A/G	2.32e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	HNSC	rs2036772	chr12:102517753	T/C	2.96e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	BRCA	rs2036772	chr12:102517753	T/C	1.58e-06
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	BRCA	rs2036772	chr12:102517753	T/C	3.83e-04
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	LGG	rs2036771	chr12:102517804	A/G	6.70e-05
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	LGG	rs2036772	chr12:102517753	T/C	1.39e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	LGG	rs2036771	chr12:102517804	A/G	1.62e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	LGG	rs2036772	chr12:102517753	T/C	2.74e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	KIRC	rs2036772	chr12:102517753	T/C	2.35e-03
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	STAD	rs2036772	chr12:102517753	T/C	1.59e-06
exon_skip_86310	12	102514024:102514064:102517663:102517819:102542007:102542241	102517663:102517819	ENST00000392909.3,ENST00000358383.5,ENST00000537257.1,ENST00000541394.1	STAD	rs2036772	chr12:102517753	T/C	8.55e-06
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	BLCA	rs2036772	chr12:102517753	T/C	5.25e-04
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	BLCA	rs2036772	chr12:102517753	T/C	9.55e-04
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	HNSC	rs2036771	chr12:102517804	A/G	2.12e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	HNSC	rs2036771	chr12:102517804	A/G	2.32e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	HNSC	rs2036772	chr12:102517753	T/C	2.96e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	BRCA	rs2036772	chr12:102517753	T/C	1.58e-06
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	BRCA	rs2036772	chr12:102517753	T/C	3.83e-04
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	LGG	rs2036771	chr12:102517804	A/G	6.70e-05
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	LGG	rs2036772	chr12:102517753	T/C	1.39e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	LGG	rs2036771	chr12:102517804	A/G	1.62e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	LGG	rs2036772	chr12:102517753	T/C	2.74e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	KIRC	rs2036772	chr12:102517753	T/C	2.35e-03
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	STAD	rs2036772	chr12:102517753	T/C	1.59e-06
exon_skip_86311	12	102514024:102514064:102517663:102517819:102542012:102542241	102517663:102517819	ENST00000392911.2	STAD	rs2036772	chr12:102517753	T/C	8.55e-06
exon_skip_86337	12	102542012:102542241:102545347:102545578:102547646:102547754	102545347:102545578	ENST00000541394.1	HNSC	rs55772007	chr12:102545563	A/G	2.30e-03
exon_skip_86337	12	102542012:102542241:102545347:102545578:102547646:102547754	102545347:102545578	ENST00000541394.1	HNSC	rs55772007	chr12:102545563	A/G	2.51e-03
exon_skip_86337	12	102542012:102542241:102545347:102545578:102547646:102547754	102545347:102545578	ENST00000541394.1	LGG	rs55772007	chr12:102545563	A/G	1.70e-04
exon_skip_86337	12	102542012:102542241:102545347:102545578:102547646:102547754	102545347:102545578	ENST00000541394.1	LGG	rs55772007	chr12:102545563	A/G	3.23e-03

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PARPBP

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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PARPBP

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RelatedDrugs for PARPBP

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

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Drug status

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RelatedDiseases for PARPBP

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

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Gene summary for PARPBP

Exon skipping events across known transcript of Ensembl for PARPBP from UCSC genome browser

Gene isoform structures and expression levels for PARPBP

Exon skipping events with PSIs in TCGA for PARPBP

Exon skipping events with PSIs in GTEx for PARPBP

Open reading frame (ORF) annotation in the exon skipping event for PARPBP

Infer the effects of exon skipping event on protein functional features for PARPBP

SNVs in the skipped exons for PARPBP

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PARPBP

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PARPBP

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PARPBP

RelatedDrugs for PARPBP

RelatedDiseases for PARPBP