|
||||||
|
 | |
| |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
| |
|
Gene summary for ATAD2B |
 Gene summary |
| Gene information | Gene symbol | ATAD2B | Gene ID | 54454 |
| Gene name | ATPase family, AAA domain containing 2B | |
| Synonyms | - | |
| Cytomap | 2p24.1-p23.3 | |
| Type of gene | protein-coding | |
| Description | ATPase family AAA domain-containing protein 2B | |
| Modification date | 20180523 | |
| UniProtAcc | Q9ULI0 | |
| Context | PubMed: ATAD2B [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
Exon skipping events across known transcript of Ensembl for ATAD2B from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Gene isoform structures and expression levels for ATAD2B |
| Expression levels of gene isoforms across TCGA. |
 |
| Expression levels of gene isoforms across GTEx. |
 |
Top |
Exon skipping events with PSIs in TCGA for ATAD2B |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_337297 | 2 | 23977516:23977644:23980287:23980971:23985078:23985216 | 23980287:23980971 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4,ENST00000474583.1 |
| exon_skip_337300 | 2 | 23985078:23985216:23988375:23988498:24005738:24005898 | 23988375:23988498 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4,ENST00000474583.1 |
| exon_skip_337301 | 2 | 24008911:24009093:24011381:24011517:24021007:24021193 | 24011381:24011517 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4,ENST00000474583.1 |
| exon_skip_337309 | 2 | 24021007:24021193:24033185:24033372:24042616:24042725 | 24033185:24033372 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4 |
| exon_skip_337314 | 2 | 24033185:24033372:24042616:24042752:24046127:24046439 | 24042616:24042752 | ENSG00000119778.10 | ENST00000238789.5,ENST00000474583.1 |
| exon_skip_337315 | 2 | 24046380:24046439:24050667:24050730:24051718:24051809 | 24050667:24050730 | ENSG00000119778.10 | ENST00000474583.1 |
| exon_skip_337317 | 2 | 24056788:24056948:24080284:24080373:24086250:24086425 | 24080284:24080373 | ENSG00000119778.10 | ENST00000238789.5 |
| exon_skip_337318 | 2 | 24080284:24080373:24086250:24086425:24087678:24087794 | 24086250:24086425 | ENSG00000119778.10 | ENST00000238789.5,ENST00000366438.2 |
| exon_skip_337320 | 2 | 24092539:24092631:24098698:24098774:24103508:24103625 | 24098698:24098774 | ENSG00000119778.10 | ENST00000238789.5,ENST00000439915.1 |
| exon_skip_337321 | 2 | 24103508:24103625:24106463:24106505:24107634:24107743 | 24106463:24106505 | ENSG00000119778.10 | ENST00000439915.1 |
| exon_skip_337322 | 2 | 24108596:24108699:24110701:24110855:24111219:24111269 | 24110701:24110855 | ENSG00000119778.10 | ENST00000238789.5,ENST00000439915.1 |
| exon_skip_337324 | 2 | 24111219:24111269:24118688:24118840:24149424:24149935 | 24118688:24118840 | ENSG00000119778.10 | ENST00000439915.1 |
| PSI values of skipped exons in TCGA. |
 |
Top |
Exon skipping events with PSIs in GTEx for ATAD2B |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_337297 | 2 | 23977516:23977644:23980287:23980971:23985078:23985216 | 23980287:23980971 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4,ENST00000474583.1 |
| exon_skip_337300 | 2 | 23985078:23985216:23988375:23988498:24005738:24005898 | 23988375:23988498 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4,ENST00000474583.1 |
| exon_skip_337301 | 2 | 24008911:24009093:24011381:24011517:24021007:24021193 | 24011381:24011517 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4,ENST00000474583.1 |
| exon_skip_337303 | 2 | 24021007:24021193:24022694:24022863:24029040:24029098 | 24022694:24022863 | ENSG00000119778.10 | ENST00000474583.1 |
| exon_skip_337309 | 2 | 24021007:24021193:24033185:24033372:24042616:24042725 | 24033185:24033372 | ENSG00000119778.10 | ENST00000238789.5,ENST00000381024.4 |
| exon_skip_337312 | 2 | 24029040:24029098:24031858:24032046:24033185:24033372 | 24031858:24032046 | ENSG00000119778.10 | ENST00000474583.1 |
| exon_skip_337314 | 2 | 24033185:24033372:24042616:24042752:24046127:24046439 | 24042616:24042752 | ENSG00000119778.10 | ENST00000238789.5,ENST00000474583.1 |
| exon_skip_337315 | 2 | 24046380:24046439:24050667:24050730:24051718:24051809 | 24050667:24050730 | ENSG00000119778.10 | ENST00000474583.1 |
| exon_skip_337317 | 2 | 24056788:24056948:24080284:24080373:24086250:24086425 | 24080284:24080373 | ENSG00000119778.10 | ENST00000238789.5 |
| exon_skip_337318 | 2 | 24080284:24080373:24086250:24086425:24087678:24087794 | 24086250:24086425 | ENSG00000119778.10 | ENST00000238789.5,ENST00000366438.2 |
| exon_skip_337319 | 2 | 24086250:24086425:24087678:24087794:24090704:24090757 | 24087678:24087794 | ENSG00000119778.10 | ENST00000238789.5,ENST00000366438.2 |
| exon_skip_337321 | 2 | 24103508:24103625:24106463:24106505:24107634:24107743 | 24106463:24106505 | ENSG00000119778.10 | ENST00000439915.1 |
| exon_skip_337322 | 2 | 24108596:24108699:24110701:24110855:24111219:24111269 | 24110701:24110855 | ENSG00000119778.10 | ENST00000238789.5,ENST00000439915.1 |
| PSI values of skipped exons in GTEx. |
 |
| * Skipped exon sequences. |
Top |
Open reading frame (ORF) annotation in the exon skipping event for ATAD2B |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000238789 | 24011381 | 24011517 | Frame-shift |
| ENST00000238789 | 24033185 | 24033372 | Frame-shift |
| ENST00000238789 | 24042616 | 24042752 | Frame-shift |
| ENST00000238789 | 24080284 | 24080373 | Frame-shift |
| ENST00000238789 | 24086250 | 24086425 | Frame-shift |
| ENST00000238789 | 24098698 | 24098774 | Frame-shift |
| ENST00000238789 | 24110701 | 24110855 | Frame-shift |
| ENST00000238789 | 23980287 | 23980971 | In-frame |
| ENST00000238789 | 23988375 | 23988498 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000238789 | 24011381 | 24011517 | Frame-shift |
| ENST00000238789 | 24033185 | 24033372 | Frame-shift |
| ENST00000238789 | 24042616 | 24042752 | Frame-shift |
| ENST00000238789 | 24080284 | 24080373 | Frame-shift |
| ENST00000238789 | 24086250 | 24086425 | Frame-shift |
| ENST00000238789 | 24087678 | 24087794 | Frame-shift |
| ENST00000238789 | 24110701 | 24110855 | Frame-shift |
| ENST00000238789 | 23980287 | 23980971 | In-frame |
| ENST00000238789 | 23988375 | 23988498 | In-frame |
Top |
Infer the effects of exon skipping event on protein functional features for ATAD2B |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
 |
| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000238789 | 8120 | 1458 | 23988375 | 23988498 | 3478 | 3600 | 1044 | 1085 |
| ENST00000238789 | 8120 | 1458 | 23980287 | 23980971 | 3739 | 4422 | 1131 | 1359 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000238789 | 8120 | 1458 | 23988375 | 23988498 | 3478 | 3600 | 1044 | 1085 |
| ENST00000238789 | 8120 | 1458 | 23980287 | 23980971 | 3739 | 4422 | 1131 | 1359 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9ULI0 | 1044 | 1085 | 1 | 1458 | Chain | ID=PRO_0000050789;Note=ATPase family AAA domain-containing protein 2B |
| Q9ULI0 | 1044 | 1085 | 975 | 1045 | Domain | Note=Bromo;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00035 |
| Q9ULI0 | 1044 | 1085 | 1043 | 1066 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3LXJ |
| Q9ULI0 | 1044 | 1085 | 1069 | 1083 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3LXJ |
| Q9ULI0 | 1131 | 1359 | 1 | 1458 | Chain | ID=PRO_0000050789;Note=ATPase family AAA domain-containing protein 2B |
| Q9ULI0 | 1131 | 1359 | 1247 | 1250 | Compositional bias | Note=Poly-Ser |
| Q9ULI0 | 1131 | 1359 | 1338 | 1338 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:21406692;Dbxref=PMID:21406692 |
| Q9ULI0 | 1131 | 1359 | 1347 | 1347 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163;Dbxref=PMID:21406692,PMID:23186163 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9ULI0 | 1044 | 1085 | 1 | 1458 | Chain | ID=PRO_0000050789;Note=ATPase family AAA domain-containing protein 2B |
| Q9ULI0 | 1044 | 1085 | 975 | 1045 | Domain | Note=Bromo;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00035 |
| Q9ULI0 | 1044 | 1085 | 1043 | 1066 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3LXJ |
| Q9ULI0 | 1044 | 1085 | 1069 | 1083 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:3LXJ |
| Q9ULI0 | 1131 | 1359 | 1 | 1458 | Chain | ID=PRO_0000050789;Note=ATPase family AAA domain-containing protein 2B |
| Q9ULI0 | 1131 | 1359 | 1247 | 1250 | Compositional bias | Note=Poly-Ser |
| Q9ULI0 | 1131 | 1359 | 1338 | 1338 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:21406692;Dbxref=PMID:21406692 |
| Q9ULI0 | 1131 | 1359 | 1347 | 1347 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163;Dbxref=PMID:21406692,PMID:23186163 |
Top |
SNVs in the skipped exons for ATAD2B |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_337297 | 23980288 | 23980971 | 23980463 | 23980463 | Frame_Shift_Del | T | - | p.K1301fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_337314 | 24042617 | 24042752 | 24042637 | 24042637 | Frame_Shift_Del | T | - | p.K749fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_337314 | 24042617 | 24042752 | 24042637 | 24042637 | Frame_Shift_Del | T | - | p.P750fs |
| KIRC | TCGA-B0-5098-01 | exon_skip_337314 | 24042617 | 24042752 | 24042679 | 24042682 | Frame_Shift_Del | TGAG | - | p.HS734fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_337317 | 24080285 | 24080373 | 24080334 | 24080334 | Frame_Shift_Del | T | - | p.I507fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_337317 | 24080285 | 24080373 | 24080341 | 24080341 | Frame_Shift_Del | A | - | p.F504fs |
| UCEC | TCGA-B5-A0JZ-01 | exon_skip_337317 | 24080285 | 24080373 | 24080341 | 24080341 | Frame_Shift_Del | A | - | p.F504fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_337318 | 24086251 | 24086425 | 24086257 | 24086257 | Frame_Shift_Del | A | - | p.F491fs |
| COAD | TCGA-AU-6004-01 | exon_skip_337318 | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.M469fs |
| COAD | TCGA-F4-6570-01 | exon_skip_337318 | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.M469fs |
| UCEC | TCGA-BG-A0M4-01 | exon_skip_337318 | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| KIRP | TCGA-G7-A8LB-01 | exon_skip_337318 | 24086251 | 24086425 | 24086371 | 24086371 | Frame_Shift_Del | T | - | p.L454X |
| COAD | TCGA-AZ-6601-01 | exon_skip_337320 | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| UCS | TCGA-ND-A4WC-01 | exon_skip_337297 | 23980288 | 23980971 | 23980888 | 23980889 | Frame_Shift_Ins | - | T | p.*1160fs |
| UCS | TCGA-ND-A4WC-01 | exon_skip_337297 | 23980288 | 23980971 | 23980888 | 23980889 | Frame_Shift_Ins | - | T | p.D1160fs |
| UCEC | TCGA-B5-A0JY-01 | exon_skip_337297 | 23980288 | 23980971 | 23980404 | 23980404 | Nonsense_Mutation | G | A | p.R597* |
| UCEC | TCGA-AP-A05A-01 | exon_skip_337309 | 24033186 | 24033372 | 24033196 | 24033196 | Nonsense_Mutation | G | C | p.S815* |
| PAAD | TCGA-IB-7651-01 | exon_skip_337309 | 24033186 | 24033372 | 24033200 | 24033200 | Nonsense_Mutation | C | A | p.E814* |
| PAAD | TCGA-IB-7651-01 | exon_skip_337309 | 24033186 | 24033372 | 24033200 | 24033200 | Nonsense_Mutation | C | A | p.E814X |
| CHOL | TCGA-W5-AA39-01 | exon_skip_337324 | 24118689 | 24118840 | 24118774 | 24118774 | Nonsense_Mutation | G | A | p.Q95* |
| CHOL | TCGA-W5-AA39-01 | exon_skip_337324 | 24118689 | 24118840 | 24118774 | 24118774 | Nonsense_Mutation | G | A | p.Q95X |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| GSU_STOMACH | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| HEC151_ENDOMETRIUM | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| HEC6_ENDOMETRIUM | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| 2313287_STOMACH | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| RKO_LARGE_INTESTINE | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| AN3CA_ENDOMETRIUM | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| SNU407_LARGE_INTESTINE | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| HCC1569_BREAST | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| SNU1040_LARGE_INTESTINE | 24086251 | 24086425 | 24086326 | 24086326 | Frame_Shift_Del | A | - | p.F468fs |
| HEC265_ENDOMETRIUM | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| SNUC2A_LARGE_INTESTINE | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| IM95_STOMACH | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| GP2D_LARGE_INTESTINE | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| GP5D_LARGE_INTESTINE | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| HEC1_ENDOMETRIUM | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| RCCFG2_KIDNEY | 24098699 | 24098774 | 24098756 | 24098756 | Frame_Shift_Del | T | - | p.K307fs |
| HCC2998_LARGE_INTESTINE | 23980288 | 23980971 | 23980888 | 23980889 | Frame_Shift_Ins | - | T | p.D1160fs |
| HCT15_LARGE_INTESTINE | 24011382 | 24011517 | 24011442 | 24011443 | Frame_Shift_Ins | - | C | p.F906fs |
| EN_ENDOMETRIUM | 24086251 | 24086425 | 24086325 | 24086326 | Frame_Shift_Ins | - | A | p.M469fs |
| MTA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 23980288 | 23980971 | 23980455 | 23980455 | Missense_Mutation | G | A | p.S1304F |
| EBC1_LUNG | 23980288 | 23980971 | 23980558 | 23980558 | Missense_Mutation | C | A | p.G1270C |
| HEC108_ENDOMETRIUM | 23980288 | 23980971 | 23980608 | 23980608 | Missense_Mutation | G | T | p.P1253Q |
| CAL51_BREAST | 23980288 | 23980971 | 23980626 | 23980626 | Missense_Mutation | C | T | p.S1247N |
| KHYG_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 23980288 | 23980971 | 23980641 | 23980641 | Missense_Mutation | G | T | p.S1242Y |
| NKL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 23980288 | 23980971 | 23980641 | 23980641 | Missense_Mutation | G | A | p.S1242F |
| RERFLCFM_LUNG | 23980288 | 23980971 | 23980644 | 23980644 | Missense_Mutation | T | C | p.E1241G |
| SNU349_KIDNEY | 23980288 | 23980971 | 23980658 | 23980658 | Missense_Mutation | C | A | p.E1236D |
| EMCBAC1_LUNG | 23980288 | 23980971 | 23980662 | 23980662 | Missense_Mutation | T | A | p.E1235V |
| HCC366_LUNG | 23980288 | 23980971 | 23980860 | 23980860 | Missense_Mutation | T | G | p.Y1169S |
| LS411N_LARGE_INTESTINE | 23988376 | 23988498 | 23988397 | 23988397 | Missense_Mutation | T | C | p.K1079E |
| SW1088_CENTRAL_NERVOUS_SYSTEM | 23988376 | 23988498 | 23988466 | 23988466 | Missense_Mutation | T | G | p.K1056Q |
| NCIH1339_LUNG | 23988376 | 23988498 | 23988479 | 23988479 | Missense_Mutation | C | A | p.R1051S |
| NCIH2172_LUNG | 24011382 | 24011517 | 24011415 | 24011415 | Missense_Mutation | C | A | p.A915S |
| HEC1A_ENDOMETRIUM | 24011382 | 24011517 | 24011415 | 24011415 | Missense_Mutation | C | T | p.A915T |
| 697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 24011382 | 24011517 | 24011472 | 24011472 | Missense_Mutation | G | C | p.Q896E |
| L540_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 24011382 | 24011517 | 24011477 | 24011477 | Missense_Mutation | T | C | p.Y894C |
| BCPAP_THYROID | 24033186 | 24033372 | 24033316 | 24033316 | Missense_Mutation | C | T | p.R775Q |
| BT474_BREAST | 24086251 | 24086425 | 24086302 | 24086302 | Missense_Mutation | C | G | p.L476F |
| HT55_LARGE_INTESTINE | 24086251 | 24086425 | 24086345 | 24086345 | Missense_Mutation | T | C | p.D462G |
| NUDUL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 24086251 | 24086425 | 24086345 | 24086345 | Missense_Mutation | T | C | p.D462G |
| SW756_CERVIX | 24098699 | 24098774 | 24098766 | 24098766 | Missense_Mutation | G | C | p.H304D |
| KYSE30_OESOPHAGUS | 24118689 | 24118840 | 24118699 | 24118699 | Missense_Mutation | C | T | p.G120R |
| EFE184_ENDOMETRIUM | 24118689 | 24118840 | 24118771 | 24118771 | Missense_Mutation | G | C | p.P96A |
| SNU1040_LARGE_INTESTINE | 24118689 | 24118840 | 24118690 | 24118690 | Splice_Site | T | A | p.R123W |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ATAD2B |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
Top |
Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ATAD2B |
Top |
Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ATAD2B |
Top |
RelatedDrugs for ATAD2B |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ATAD2B |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|