ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for LCMT1

Gene summary

Gene information	Gene symbol	LCMT1
	Gene ID	51451
	Gene name	leucine carboxyl methyltransferase 1
	Synonyms	CGI-68\|LCMT\|PPMT1
	Cytomap	16p12.1
	Type of gene	protein-coding
	Description	leucine carboxyl methyltransferase 1[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1protein phosphatase methyltransferase 1protein-leucine O-methyltransferase
	Modification date	20180523
	UniProtAcc	Q9UIC8
	Context	PubMed: LCMT1 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
LCMT1	GO:0006481	C-terminal protein methylation	10600115

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Exon skipping events across known transcript of Ensembl for LCMT1 from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Gene isoform structures and expression levels for LCMT1

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

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Exon skipping events with PSIs in TCGA for LCMT1

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_134818	16	25123065:25123089:25139795:25139887:25143722:25143844	25139795:25139887	ENSG00000205629.7	ENST00000577157.1
exon_skip_134821	16	25123252:25123317:25137284:25137447:25139795:25139887	25137284:25137447	ENSG00000205629.7	ENST00000380962.5
exon_skip_134823	16	25123252:25123317:25139795:25139887:25143722:25143844	25139795:25139887	ENSG00000205629.7	ENST00000570981.1,ENST00000380966.4
exon_skip_134825	16	25123252:25123317:25139795:25139891:25143722:25143844	25139795:25139891	ENSG00000205629.7	ENST00000564011.1
exon_skip_134837	16	25139795:25139887:25143722:25143844:25151491:25151568	25143722:25143844	ENSG00000205629.7	ENST00000577157.1,ENST00000570981.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4
exon_skip_134843	16	25143722:25143844:25151491:25151568:25162874:25162936	25151491:25151568	ENSG00000205629.7	ENST00000577157.1,ENST00000380962.5,ENST00000399069.3
exon_skip_134846	16	25143722:25143844:25151491:25151568:25175918:25176039	25151491:25151568	ENSG00000205629.7	ENST00000564011.1,ENST00000380966.4
exon_skip_134854	16	25151496:25151568:25162874:25162936:25172422:25172489	25162874:25162936	ENSG00000205629.7	ENST00000576625.1,ENST00000380962.5,ENST00000399069.3
exon_skip_134861	16	25162874:25162936:25172422:25172525:25175918:25176039	25172422:25172525	ENSG00000205629.7	ENST00000576625.1,ENST00000380962.5,ENST00000399069.3,ENST00000572869.1
exon_skip_134863	16	25176010:25176039:25180432:25180534:25182034:25182118	25180432:25180534	ENSG00000205629.7	ENST00000564011.1,ENST00000380962.5,ENST00000575396.1,ENST00000399069.3,ENST00000572869.1,ENST00000380966.4
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENSG00000205629.7	ENST00000572869.1
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENSG00000205629.7	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENSG00000205629.7	ENST00000575396.1
exon_skip_134868	16	25180432:25180534:25186257:25186355:25189321:25189344	25186257:25186355	ENSG00000205629.7	ENST00000576625.1
exon_skip_134869	16	25182034:25182118:25186257:25186355:25189321:25189344	25186257:25186355	ENSG00000205629.7	ENST00000572869.1
exon_skip_134870	16	25182034:25182126:25186257:25186355:25189321:25189344	25186257:25186355	ENSG00000205629.7	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4

PSI values of skipped exons in TCGA.

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Exon skipping events with PSIs in GTEx for LCMT1

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_134818	16	25123065:25123089:25139795:25139887:25143722:25143844	25139795:25139887	ENSG00000205629.7	ENST00000577157.1
exon_skip_134821	16	25123252:25123317:25137284:25137447:25139795:25139887	25137284:25137447	ENSG00000205629.7	ENST00000380962.5
exon_skip_134823	16	25123252:25123317:25139795:25139887:25143722:25143844	25139795:25139887	ENSG00000205629.7	ENST00000380966.4,ENST00000570981.1
exon_skip_134837	16	25139795:25139887:25143722:25143844:25151491:25151568	25143722:25143844	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000380966.4,ENST00000577157.1,ENST00000570981.1
exon_skip_134843	16	25143722:25143844:25151491:25151568:25162874:25162936	25151491:25151568	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000577157.1
exon_skip_134846	16	25143722:25143844:25151491:25151568:25175918:25176039	25151491:25151568	ENSG00000205629.7	ENST00000380966.4,ENST00000564011.1
exon_skip_134854	16	25151496:25151568:25162874:25162936:25172422:25172489	25162874:25162936	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000576625.1
exon_skip_134861	16	25162874:25162936:25172422:25172525:25175918:25176039	25172422:25172525	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000576625.1,ENST00000572869.1
exon_skip_134863	16	25176010:25176039:25180432:25180534:25182034:25182118	25180432:25180534	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000380966.4,ENST00000564011.1,ENST00000572869.1,ENST00000575396.1
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENSG00000205629.7	ENST00000572869.1
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000380966.4,ENST00000564011.1
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENSG00000205629.7	ENST00000575396.1
exon_skip_134868	16	25180432:25180534:25186257:25186355:25189321:25189344	25186257:25186355	ENSG00000205629.7	ENST00000576625.1
exon_skip_134869	16	25182034:25182118:25186257:25186355:25189321:25189344	25186257:25186355	ENSG00000205629.7	ENST00000572869.1
exon_skip_134870	16	25182034:25182126:25186257:25186355:25189321:25189344	25186257:25186355	ENSG00000205629.7	ENST00000399069.3,ENST00000380962.5,ENST00000380966.4,ENST00000564011.1

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for LCMT1

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000399069	25143722	25143844	Frame-shift
ENST00000399069	25151491	25151568	Frame-shift
ENST00000399069	25162874	25162936	Frame-shift
ENST00000399069	25172422	25172525	Frame-shift
ENST00000399069	25182034	25182126	Frame-shift
ENST00000399069	25186257	25186355	Frame-shift
ENST00000399069	25180432	25180534	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000399069	25143722	25143844	Frame-shift
ENST00000399069	25151491	25151568	Frame-shift
ENST00000399069	25162874	25162936	Frame-shift
ENST00000399069	25172422	25172525	Frame-shift
ENST00000399069	25182034	25182126	Frame-shift
ENST00000399069	25186257	25186355	Frame-shift
ENST00000399069	25180432	25180534	In-frame

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Infer the effects of exon skipping event on protein functional features for LCMT1

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000399069	1385	334	25180432	25180534	846	947	230	264

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000399069	1385	334	25180432	25180534	846	947	230	264

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
Q9UIC8	230	264	221	230	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	1	334	Chain	ID=PRO_0000204422;Note=Leucine carboxyl methyltransferase 1
Q9UIC8	230	264	236	246	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	255	259	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	261	269	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	248	249	Sequence conflict	Note=RQ->PS;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q9UIC8	230	264	251	251	Sequence conflict	Note=D->E;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q9UIC8	230	264	247	249	Turn	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
Q9UIC8	230	264	221	230	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	1	334	Chain	ID=PRO_0000204422;Note=Leucine carboxyl methyltransferase 1
Q9UIC8	230	264	236	246	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	255	259	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	261	269	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI
Q9UIC8	230	264	248	249	Sequence conflict	Note=RQ->PS;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q9UIC8	230	264	251	251	Sequence conflict	Note=D->E;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q9UIC8	230	264	247	249	Turn	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3IEI

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SNVs in the skipped exons for LCMT1

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

LCMT1_BRCA_exon_skip_134821_psi_boxplot.png
boxplot

LCMT1_SKCM_exon_skip_134861_psi_boxplot.png
boxplot

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
LIHC	TCGA-DD-A1EG-01	exon_skip_134837	25143723	25143844	25143727	25143727	Frame_Shift_Del	T	-	p.Y70fs
BLCA	TCGA-DK-A6B6-01	exon_skip_134837	25143723	25143844	25143746	25143746	Frame_Shift_Del	G	-	p.V77fs
SKCM	TCGA-DA-A1HY-06	exon_skip_134861	25172423	25172525	25172473	25172473	Nonsense_Mutation	C	T	p.R173*
SKCM	TCGA-DA-A1HY-06	exon_skip_134861	25172423	25172525	25172473	25172473	Nonsense_Mutation	C	T	p.R173X
SKCM	TCGA-EE-A2GS-06	exon_skip_134861	25172423	25172525	25172473	25172473	Nonsense_Mutation	C	T	p.R173*
LUSC	TCGA-18-3406-01	exon_skip_134869 exon_skip_134870 exon_skip_134868	25186258	25186355	25186343	25186343	Nonsense_Mutation	G	T	p.G324*
BRCA	TCGA-A8-A06N-01	exon_skip_134821	25137285	25137447	25137449	25137449	Splice_Site	A	T	e1+2
THCA	TCGA-EM-A22O-01	exon_skip_134867 exon_skip_134866	25182035	25182126	25182127	25182127	Splice_Site	G	A	.

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons	Mutation description
	Sample: TCGA-DA-A1HY-06
	Cancer type: SKCM
	ESID: exon_skip_134861
	Skipped exon start: 25172423
	Skipped exon end: 25172525
	Mutation start: 25172473
	Mutation end: 25172473
	Mutation type: Nonsense_Mutation
	Reference seq: C
	Mutation seq: T
	AAchange: p.R173X
	Sample: TCGA-DA-A1HY-06
	Cancer type: SKCM
	ESID: exon_skip_134861
	Skipped exon start: 25172423
	Skipped exon end: 25172525
	Mutation start: 25172473
	Mutation end: 25172473
	Mutation type: Nonsense_Mutation
	Reference seq: C
	Mutation seq: T
	AAchange: p.R173*
exon_skip_134861_SKCM_TCGA-DA-A1HY-06.png
exon_skip_476825_SKCM_TCGA-DA-A1HY-06.png
	Sample: TCGA-EE-A2GS-06
	Cancer type: SKCM
	ESID: exon_skip_134861
	Skipped exon start: 25172423
	Skipped exon end: 25172525
	Mutation start: 25172473
	Mutation end: 25172473
	Mutation type: Nonsense_Mutation
	Reference seq: C
	Mutation seq: T
	AAchange: p.R173*
exon_skip_134861_SKCM_TCGA-EE-A2GS-06.png
	Sample: TCGA-A8-A06N-01
	Cancer type: BRCA
	ESID: exon_skip_134821
	Skipped exon start: 25137285
	Skipped exon end: 25137447
	Mutation start: 25137449
	Mutation end: 25137449
	Mutation type: Splice_Site
	Reference seq: A
	Mutation seq: T
	AAchange: e1+2
exon_skip_134821_BRCA_TCGA-A8-A06N-01.png
exon_skip_2974_BRCA_TCGA-A8-A06N-01.png

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
DND41_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	25162875	25162936	25162910	25162910	Missense_Mutation	T	C	p.L147P
D336MG_CENTRAL_NERVOUS_SYSTEM	25180433	25180534	25180497	25180497	Missense_Mutation	T	C	p.L252P
MDAMB453_BREAST	25143723	25143844	25143752	25143752	Nonsense_Mutation	C	T	p.Q79*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for LCMT1

sQTL information located at the skipped exons.

Exon skip ID	Chromosome	Three exons	Skippped exon	ENST	Cancer type	SNP id	Location	DNA change (ref/var)	P-value
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	COAD	rs9630611	chr16:25182032	A/G	6.95e-05
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	BLCA	rs9630611	chr16:25182032	A/G	2.12e-03
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	BRCA	rs9630611	chr16:25182032	A/G	3.74e-08
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	KIRP	rs9630611	chr16:25182032	A/G	4.85e-06
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	LGG	rs9630611	chr16:25182032	A/G	6.83e-05
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	KIRC	rs9630611	chr16:25182032	A/G	1.97e-05
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	LUSC	rs9630611	chr16:25182032	A/G	2.34e-04
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	PCPG	rs9630611	chr16:25182032	A/G	1.41e-06
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	PRAD	rs9630611	chr16:25182032	A/G	4.72e-04
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	STAD	rs9630611	chr16:25182032	A/G	4.11e-05
exon_skip_134867	16	25180432:25180534:25182034:25182126:25189321:25189344	25182034:25182126	ENST00000575396.1	THCA	rs9630611	chr16:25182032	A/G	3.00e-06
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	COAD	rs9630611	chr16:25182032	A/G	6.95e-05
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	BLCA	rs9630611	chr16:25182032	A/G	2.12e-03
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	BRCA	rs9630611	chr16:25182032	A/G	3.74e-08
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	KIRP	rs9630611	chr16:25182032	A/G	4.85e-06
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	LGG	rs9630611	chr16:25182032	A/G	6.83e-05
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	KIRC	rs9630611	chr16:25182032	A/G	1.97e-05
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	LUSC	rs9630611	chr16:25182032	A/G	2.34e-04
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	PCPG	rs9630611	chr16:25182032	A/G	1.41e-06
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	PRAD	rs9630611	chr16:25182032	A/G	4.72e-04
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	STAD	rs9630611	chr16:25182032	A/G	4.11e-05
exon_skip_134866	16	25180432:25180534:25182034:25182126:25186257:25186355	25182034:25182126	ENST00000564011.1,ENST00000380962.5,ENST00000399069.3,ENST00000380966.4	THCA	rs9630611	chr16:25182032	A/G	3.00e-06
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	COAD	rs9630611	chr16:25182032	A/G	6.95e-05
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	BLCA	rs9630611	chr16:25182032	A/G	2.12e-03
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	BRCA	rs9630611	chr16:25182032	A/G	3.74e-08
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	KIRP	rs9630611	chr16:25182032	A/G	4.85e-06
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	LGG	rs9630611	chr16:25182032	A/G	6.83e-05
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	KIRC	rs9630611	chr16:25182032	A/G	1.97e-05
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	LUSC	rs9630611	chr16:25182032	A/G	2.34e-04
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	PCPG	rs9630611	chr16:25182032	A/G	1.41e-06
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	PRAD	rs9630611	chr16:25182032	A/G	4.72e-04
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	STAD	rs9630611	chr16:25182032	A/G	4.11e-05
exon_skip_134864	16	25180432:25180534:25182034:25182118:25186257:25186355	25182034:25182118	ENST00000572869.1	THCA	rs9630611	chr16:25182032	A/G	3.00e-06

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for LCMT1

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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for LCMT1

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RelatedDrugs for LCMT1

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for LCMT1

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
LCMT1	C0752351	Embryo Loss	1	CTD_human

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

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