|
||||||
|
 | |
| |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
| |
|
Gene summary for ZNF506 |
 Gene summary |
| Gene information | Gene symbol | ZNF506 | Gene ID | 440515 |
| Gene name | zinc finger protein 506 | |
| Synonyms | - | |
| Cytomap | 19p13.11 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 506 | |
| Modification date | 20180519 | |
| UniProtAcc | Q5JVG8 | |
| Context | PubMed: ZNF506 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
Exon skipping events across known transcript of Ensembl for ZNF506 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Gene isoform structures and expression levels for ZNF506 |
| Expression levels of gene isoforms across TCGA. |
 |
| Expression levels of gene isoforms across GTEx. |
 |
Top |
Exon skipping events with PSIs in TCGA for ZNF506 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_316925 | 19 | 19897370:19897663:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000587461.1 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENSG00000081665.9 | ENST00000591639.1,ENST00000443905.2 |
| exon_skip_316930 | 19 | 19903269:19903293:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000590766.1,ENST00000586260.1 |
| exon_skip_316931 | 19 | 19906021:19906469:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000591639.1,ENST00000540806.2,ENST00000443905.2 |
| exon_skip_316934 | 19 | 19906021:19906469:19917750:19917877:19932409:19932501 | 19917750:19917877 | ENSG00000081665.9 | ENST00000450683.2 |
| exon_skip_316935 | 19 | 19909597:19910259:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000545006.1 |
| exon_skip_316937 | 19 | 19916839:19916935:19917750:19917877:19932409:19932501 | 19917750:19917877 | ENSG00000081665.9 | ENST00000590766.1,ENST00000587452.1,ENST00000587461.1,ENST00000540806.2,ENST00000586260.1,ENST00000443905.2,ENST00000545006.1 |
| PSI values of skipped exons in TCGA. |
 |
Top |
Exon skipping events with PSIs in GTEx for ZNF506 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_316925 | 19 | 19897370:19897663:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000587461.1 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENSG00000081665.9 | ENST00000591639.1,ENST00000443905.2 |
| exon_skip_316930 | 19 | 19903269:19903293:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000586260.1,ENST00000590766.1 |
| exon_skip_316931 | 19 | 19906021:19906469:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000591639.1,ENST00000443905.2,ENST00000540806.2 |
| exon_skip_316934 | 19 | 19906021:19906469:19917750:19917877:19932409:19932501 | 19917750:19917877 | ENSG00000081665.9 | ENST00000450683.2 |
| exon_skip_316935 | 19 | 19909597:19910259:19916839:19916935:19917750:19917877 | 19916839:19916935 | ENSG00000081665.9 | ENST00000545006.1 |
| exon_skip_316937 | 19 | 19916839:19916935:19917750:19917877:19932409:19932501 | 19917750:19917877 | ENSG00000081665.9 | ENST00000587461.1,ENST00000586260.1,ENST00000590766.1,ENST00000443905.2,ENST00000540806.2,ENST00000587452.1,ENST00000545006.1 |
| PSI values of skipped exons in GTEx. |
 |
| * Skipped exon sequences. |
Top |
Open reading frame (ORF) annotation in the exon skipping event for ZNF506 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000443905 | 19904642 | 19906469 | 5CDS-5UTR |
| ENST00000443905 | 19917750 | 19917877 | Frame-shift |
| ENST00000540806 | 19917750 | 19917877 | Frame-shift |
| ENST00000443905 | 19916839 | 19916935 | In-frame |
| ENST00000540806 | 19916839 | 19916935 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000443905 | 19904642 | 19906469 | 5CDS-5UTR |
| ENST00000443905 | 19917750 | 19917877 | Frame-shift |
| ENST00000540806 | 19917750 | 19917877 | Frame-shift |
| ENST00000443905 | 19916839 | 19916935 | In-frame |
| ENST00000540806 | 19916839 | 19916935 | In-frame |
Top |
Infer the effects of exon skipping event on protein functional features for ZNF506 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
 |
| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000443905 | 2892 | 444 | 19916839 | 19916935 | 279 | 374 | 43 | 75 |
| ENST00000540806 | 1441 | 444 | 19916839 | 19916935 | 220 | 315 | 43 | 75 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000443905 | 2892 | 444 | 19916839 | 19916935 | 279 | 374 | 43 | 75 |
| ENST00000540806 | 1441 | 444 | 19916839 | 19916935 | 220 | 315 | 43 | 75 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q5JVG8 | 43 | 75 | 44 | 75 | Alternative sequence | ID=VSP_040653;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q5JVG8 | 43 | 75 | 44 | 75 | Alternative sequence | ID=VSP_040653;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q5JVG8 | 43 | 75 | 1 | 444 | Chain | ID=PRO_0000047624;Note=Zinc finger protein 506 |
| Q5JVG8 | 43 | 75 | 1 | 444 | Chain | ID=PRO_0000047624;Note=Zinc finger protein 506 |
| Q5JVG8 | 43 | 75 | 4 | 75 | Domain | Note=KRAB;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00119 |
| Q5JVG8 | 43 | 75 | 4 | 75 | Domain | Note=KRAB;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00119 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q5JVG8 | 43 | 75 | 44 | 75 | Alternative sequence | ID=VSP_040653;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q5JVG8 | 43 | 75 | 44 | 75 | Alternative sequence | ID=VSP_040653;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q5JVG8 | 43 | 75 | 1 | 444 | Chain | ID=PRO_0000047624;Note=Zinc finger protein 506 |
| Q5JVG8 | 43 | 75 | 1 | 444 | Chain | ID=PRO_0000047624;Note=Zinc finger protein 506 |
| Q5JVG8 | 43 | 75 | 4 | 75 | Domain | Note=KRAB;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00119 |
| Q5JVG8 | 43 | 75 | 4 | 75 | Domain | Note=KRAB;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00119 |
Top |
SNVs in the skipped exons for ZNF506 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-AAD0-01 | exon_skip_316928 | 19904643 | 19906469 | 19905517 | 19905544 | Frame_Shift_Del | TCCAGTATGAATTATCTTATGTTCAGTT | - | p.385_394del |
| STAD | TCGA-CG-5728-01 | exon_skip_316928 | 19904643 | 19906469 | 19905597 | 19905598 | Frame_Shift_Del | TC | - | p.367_367del |
| STAD | TCGA-CG-5728-01 | exon_skip_316928 | 19904643 | 19906469 | 19905597 | 19905598 | Frame_Shift_Del | TC | - | p.K367fs |
| UCEC | TCGA-D1-A101-01 | exon_skip_316928 | 19904643 | 19906469 | 19906183 | 19906183 | Frame_Shift_Del | T | - | p.K171fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| STAD | TCGA-BR-8361-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906352 | Frame_Shift_Del | TT | - | p.115_116del |
| STAD | TCGA-D7-A6EY-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.G116fs |
| STAD | TCGA-D7-A6EY-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| STAD | TCGA-MX-A5UJ-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.G116fs |
| STAD | TCGA-MX-A5UJ-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| THYM | TCGA-ZB-A966-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.G116fs |
| THYM | TCGA-ZB-A966-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| UCEC | TCGA-AX-A064-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| UCEC | TCGA-D1-A17R-01 | exon_skip_316928 | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| STAD | TCGA-BR-4201-01 | exon_skip_316925 exon_skip_316935 exon_skip_316931 exon_skip_316930 | 19916840 | 19916935 | 19916883 | 19916883 | Frame_Shift_Del | T | - | p.P62fs |
| STAD | TCGA-BR-4280-01 | exon_skip_316925 exon_skip_316935 exon_skip_316931 exon_skip_316930 | 19916840 | 19916935 | 19916883 | 19916883 | Frame_Shift_Del | T | - | p.P62fs |
| COAD | TCGA-AA-3713-01 | exon_skip_316928 | 19904643 | 19906469 | 19906350 | 19906351 | Frame_Shift_Ins | - | T | p.G84fs |
| COAD | TCGA-DM-A1D8-01 | exon_skip_316928 | 19904643 | 19906469 | 19906350 | 19906351 | Frame_Shift_Ins | - | T | p.G84fs |
| CESC | TCGA-FU-A3HY-01 | exon_skip_316928 | 19904643 | 19906469 | 19905635 | 19905635 | Nonsense_Mutation | G | C | p.S354* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| C33A_CERVIX | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| DV90_LUNG | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| HEC151_ENDOMETRIUM | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| HEC59_ENDOMETRIUM | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| AN3CA_ENDOMETRIUM | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| OCUBM_BREAST | 19904643 | 19906469 | 19906351 | 19906351 | Frame_Shift_Del | T | - | p.K115fs |
| HEC1A_ENDOMETRIUM | 19904643 | 19906469 | 19906350 | 19906351 | Frame_Shift_Ins | - | T | p.G116fs |
| SW684_SOFT_TISSUE | 19904643 | 19906469 | 19905444 | 19905444 | Missense_Mutation | T | A | p.I418F |
| M07E_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19904643 | 19906469 | 19905458 | 19905458 | Missense_Mutation | T | C | p.N413S |
| SCC3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19904643 | 19906469 | 19905511 | 19905511 | Missense_Mutation | T | G | p.K395N |
| GEO_LARGE_INTESTINE | 19904643 | 19906469 | 19905567 | 19905567 | Missense_Mutation | C | T | p.A377T |
| MDAMB361_BREAST | 19904643 | 19906469 | 19905616 | 19905616 | Missense_Mutation | C | G | p.K360N |
| HEC108_ENDOMETRIUM | 19904643 | 19906469 | 19905698 | 19905698 | Missense_Mutation | C | A | p.R333I |
| HEC1_ENDOMETRIUM | 19904643 | 19906469 | 19905830 | 19905830 | Missense_Mutation | T | C | p.K289R |
| SNU1040_LARGE_INTESTINE | 19904643 | 19906469 | 19905960 | 19905960 | Missense_Mutation | T | C | p.T246A |
| HCT15_LARGE_INTESTINE | 19904643 | 19906469 | 19906051 | 19906051 | Missense_Mutation | G | T | p.H215Q |
| COLO668_LUNG | 19904643 | 19906469 | 19906067 | 19906067 | Missense_Mutation | T | C | p.Y210C |
| ESS1_ENDOMETRIUM | 19904643 | 19906469 | 19906078 | 19906078 | Missense_Mutation | A | C | p.C206W |
| EPLC272H_LUNG | 19904643 | 19906469 | 19906086 | 19906086 | Missense_Mutation | C | T | p.E204K |
| L82_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19904643 | 19906469 | 19906121 | 19906121 | Missense_Mutation | T | G | p.K192T |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 19904643 | 19906469 | 19906205 | 19906205 | Missense_Mutation | T | C | p.K164R |
| SNU81_LARGE_INTESTINE | 19904643 | 19906469 | 19906288 | 19906288 | Missense_Mutation | A | C | p.C136W |
| REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19904643 | 19906469 | 19906325 | 19906325 | Missense_Mutation | G | A | p.P124L |
| HCT116_LARGE_INTESTINE | 19916840 | 19916935 | 19916921 | 19916921 | Missense_Mutation | T | C | p.K49E |
| MDAMB415_BREAST | 19917751 | 19917877 | 19917805 | 19917805 | Missense_Mutation | G | A | p.R26W |
| KM12_LARGE_INTESTINE | 19917751 | 19917877 | 19917847 | 19917847 | Missense_Mutation | C | T | p.E12K |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNF506 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | ACC | rs72620573 | chr19:19905169 | A/C | 9.06e-10 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | ACC | rs72620573 | chr19:19905169 | A/C | 2.46e-08 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | DLBC | rs72620573 | chr19:19905169 | A/C | 8.57e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | GBM | rs72620573 | chr19:19905169 | A/C | 1.13e-25 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | GBM | rs72620573 | chr19:19905169 | A/C | 9.79e-24 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | GBM | rs72620573 | chr19:19905169 | A/C | 7.55e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | CESC | rs72620573 | chr19:19905169 | A/C | 1.01e-17 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | COAD | rs72620573 | chr19:19905169 | A/C | 2.77e-52 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | COAD | rs72620573 | chr19:19905169 | A/C | 4.18e-18 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | COAD | rs72620573 | chr19:19905169 | A/C | 4.26e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | COAD | rs12975121 | chr19:19905011 | C/T | 2.35e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | BLCA | rs72620573 | chr19:19905169 | A/C | 4.49e-59 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | BLCA | rs72620573 | chr19:19905169 | A/C | 2.14e-25 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | BLCA | rs12975121 | chr19:19905011 | C/T | 7.55e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | ESCA | rs72620573 | chr19:19905169 | A/C | 6.98e-25 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | ESCA | rs72620573 | chr19:19905169 | A/C | 1.68e-11 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | ESCA | rs12975121 | chr19:19905011 | C/T | 1.87e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | HNSC | rs72620573 | chr19:19905169 | A/C | 1.79e-66 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | HNSC | rs72620573 | chr19:19905169 | A/C | 7.95e-09 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | BRCA | rs12975121 | chr19:19905011 | C/T | 7.67e-12 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | BRCA | rs12975121 | chr19:19905011 | C/T | 1.23e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | BRCA | rs12975121 | chr19:19905011 | C/T | 7.63e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KICH | rs72620573 | chr19:19905169 | A/C | 2.39e-10 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KICH | rs72620573 | chr19:19905169 | A/C | 1.05e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LAML | rs72620573 | chr19:19905169 | A/C | 4.80e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRP | rs72620573 | chr19:19905169 | A/C | 1.05e-41 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRP | rs72620573 | chr19:19905169 | A/C | 6.76e-15 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRP | rs72620573 | chr19:19905169 | A/C | 4.18e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LGG | rs72620573 | chr19:19905169 | A/C | 1.07e-99 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LGG | rs72620573 | chr19:19905169 | A/C | 1.50e-76 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LGG | rs72620573 | chr19:19905169 | A/C | 5.46e-27 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LGG | rs12975121 | chr19:19905011 | C/T | 1.27e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LGG | rs72620573 | chr19:19905169 | A/C | 2.38e-03 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRC | rs72620573 | chr19:19905169 | A/C | 6.42e-94 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRC | rs72620573 | chr19:19905169 | A/C | 5.05e-32 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRC | rs72620573 | chr19:19905169 | A/C | 2.79e-14 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRC | rs12975121 | chr19:19905011 | C/T | 8.01e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | KIRC | rs12975121 | chr19:19905011 | C/T | 5.67e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LUAD | rs12975121 | chr19:19905011 | C/T | 1.30e-03 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | MESO | rs72620573 | chr19:19905169 | A/C | 4.99e-12 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | MESO | rs72620573 | chr19:19905169 | A/C | 3.65e-08 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LIHC | rs72620573 | chr19:19905169 | A/C | 8.16e-28 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LIHC | rs72620573 | chr19:19905169 | A/C | 1.56e-08 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LUSC | rs72620573 | chr19:19905169 | A/C | 3.54e-66 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LUSC | rs72620573 | chr19:19905169 | A/C | 1.63e-22 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LUSC | rs12975121 | chr19:19905011 | C/T | 1.17e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | LUSC | rs72620573 | chr19:19905169 | A/C | 1.13e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | OV | rs72620573 | chr19:19905169 | A/C | 1.75e-48 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | OV | rs72620573 | chr19:19905169 | A/C | 1.72e-39 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | OV | rs72620573 | chr19:19905169 | A/C | 6.44e-07 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | READ | rs72620573 | chr19:19905169 | A/C | 9.09e-14 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | READ | rs72620573 | chr19:19905169 | A/C | 3.12e-07 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PCPG | rs72620573 | chr19:19905169 | A/C | 8.85e-34 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PCPG | rs72620573 | chr19:19905169 | A/C | 3.98e-15 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PCPG | rs72620573 | chr19:19905169 | A/C | 2.86e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PAAD | rs72620573 | chr19:19905169 | A/C | 7.06e-33 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PAAD | rs72620573 | chr19:19905169 | A/C | 1.73e-12 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PAAD | rs72620573 | chr19:19905169 | A/C | 4.40e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PRAD | rs72620573 | chr19:19905169 | A/C | 6.55e-85 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PRAD | rs72620573 | chr19:19905169 | A/C | 4.65e-56 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PRAD | rs72620573 | chr19:19905169 | A/C | 2.99e-09 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PRAD | rs12975121 | chr19:19905011 | C/T | 9.29e-07 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | PRAD | rs12975121 | chr19:19905011 | C/T | 1.62e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | SARC | rs72620573 | chr19:19905169 | A/C | 4.33e-37 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | SARC | rs72620573 | chr19:19905169 | A/C | 6.55e-17 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | SARC | rs12975121 | chr19:19905011 | C/T | 7.36e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | TGCT | rs72620573 | chr19:19905169 | A/C | 2.13e-13 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | TGCT | rs72620573 | chr19:19905169 | A/C | 1.73e-06 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | SKCM | rs72620573 | chr19:19905169 | A/C | 7.27e-19 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | SKCM | rs72620573 | chr19:19905169 | A/C | 1.36e-10 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | STAD | rs72620573 | chr19:19905169 | A/C | 5.72e-59 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | STAD | rs72620573 | chr19:19905169 | A/C | 6.63e-46 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | STAD | rs12975121 | chr19:19905011 | C/T | 6.22e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | STAD | rs12975121 | chr19:19905011 | C/T | 6.79e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | THCA | rs72620573 | chr19:19905169 | A/C | 3.05e-85 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | THCA | rs72620573 | chr19:19905169 | A/C | 1.02e-45 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | THCA | rs72620573 | chr19:19905169 | A/C | 5.57e-18 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | THCA | rs12975121 | chr19:19905011 | C/T | 9.37e-07 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | THCA | rs12975121 | chr19:19905011 | C/T | 5.17e-05 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | THCA | rs12975121 | chr19:19905011 | C/T | 5.39e-04 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | UVM | rs72620573 | chr19:19905169 | A/C | 8.37e-17 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | UVM | rs72620573 | chr19:19905169 | A/C | 1.59e-07 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | UCEC | rs72620573 | chr19:19905169 | A/C | 1.24e-12 |
| exon_skip_316928 | 19 | 19903269:19903293:19904642:19906469:19916839:19916935 | 19904642:19906469 | ENST00000591639.1,ENST00000443905.2 | UCEC | rs72620573 | chr19:19905169 | A/C | 7.04e-04 |
Top |
Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF506 |
Top |
Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF506 |
Top |
RelatedDrugs for ZNF506 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNF506 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|