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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for LMO7 |
 Gene summary |
| Gene information | Gene symbol | LMO7 | Gene ID | 4008 |
| Gene name | LIM domain 7 | |
| Synonyms | FBX20|FBXO20|LMO7b|LOMP | |
| Cytomap | 13q22.2 | |
| Type of gene | protein-coding | |
| Description | LIM domain only protein 7F-box only protein 20F-box protein Fbx20LIM domain only 7 proteinLMO-7zinc-finger domain-containing protein | |
| Modification date | 20180522 | |
| UniProtAcc | Q8WWI1 | |
| Context | PubMed: LMO7 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| LMO7 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 17067998 |
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Exon skipping events across known transcript of Ensembl for LMO7 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for LMO7 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for LMO7 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_100767 | 13 | 76194569:76196004:76197406:76197456:76287317:76287388 | 76197406:76197456 | ENSG00000136153.15 | ENST00000377534.3,ENST00000357063.3 |
| exon_skip_100773 | 13 | 76209945:76210026:76287317:76287388:76301164:76301234 | 76287317:76287388 | ENSG00000136153.15 | ENST00000533305.1 |
| exon_skip_100785 | 13 | 76210791:76210862:76287317:76287388:76301164:76301234 | 76287317:76287388 | ENSG00000136153.15 | ENST00000377499.5 |
| exon_skip_100793 | 13 | 76287317:76287388:76301164:76301234:76335067:76335174 | 76301164:76301234 | ENSG00000136153.15 | ENST00000377499.5,ENST00000377534.3,ENST00000533305.1,ENST00000341547.4,ENST00000357063.3 |
| exon_skip_100796 | 13 | 76301164:76301234:76335067:76335174:76369536:76369567 | 76335067:76335174 | ENSG00000136153.15 | ENST00000377499.5,ENST00000377534.3,ENST00000533305.1,ENST00000341547.4,ENST00000357063.3 |
| exon_skip_100799 | 13 | 76335067:76335174:76369536:76369567:76370771:76370885 | 76369536:76369567 | ENSG00000136153.15 | ENST00000377499.5,ENST00000465261.2,ENST00000526202.1,ENST00000534657.1,ENST00000321797.8,ENST00000377534.3,ENST00000533305.1,ENST00000465309.2,ENST00000341547.4,ENST00000357063.3 |
| exon_skip_100805 | 13 | 76378455:76378677:76379614:76379896:76381615:76381823 | 76379614:76379896 | ENSG00000136153.15 | ENST00000465261.2,ENST00000321797.8,ENST00000377534.3,ENST00000357063.3 |
| exon_skip_100809 | 13 | 76378455:76378677:76381615:76382335:76383289:76383319 | 76381615:76382335 | ENSG00000136153.15 | ENST00000447038.1 |
| exon_skip_100811 | 13 | 76378455:76378677:76383289:76383319:76391296:76391414 | 76383289:76383319 | ENSG00000136153.15 | ENST00000377499.5,ENST00000489941.2,ENST00000341547.4,ENST00000497947.2 |
| exon_skip_100816 | 13 | 76393528:76393671:76395312:76395745:76397700:76398009 | 76395312:76395745 | ENSG00000136153.15 | ENST00000377499.5,ENST00000465261.2,ENST00000526202.1,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000447038.1 |
| exon_skip_100817 | 13 | 76397845:76398009:76407186:76407301:76408361:76408523 | 76407186:76407301 | ENSG00000136153.15 | ENST00000377499.5,ENST00000465261.2,ENST00000524651.1,ENST00000526202.1,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000485987.1,ENST00000447038.1 |
| exon_skip_100818 | 13 | 76408434:76408523:76409287:76409475:76410532:76410593 | 76409287:76409475 | ENSG00000136153.15 | ENST00000524651.1,ENST00000526202.1,ENST00000485987.1 |
| exon_skip_100819 | 13 | 76408434:76408523:76409368:76409475:76410532:76410593 | 76409368:76409475 | ENSG00000136153.15 | ENST00000377499.5,ENST00000465261.2,ENST00000525107.2,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000525914.1,ENST00000447038.1 |
| exon_skip_100820 | 13 | 76410532:76410593:76412275:76412332:76414220:76414246 | 76412275:76412332 | ENSG00000136153.15 | ENST00000377499.5,ENST00000465261.2,ENST00000526202.1,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000447038.1 |
| exon_skip_100822 | 13 | 76412275:76412332:76412482:76412524:76414220:76414246 | 76412482:76412524 | ENSG00000136153.15 | ENST00000525107.2 |
| exon_skip_100823 | 13 | 76414526:76414631:76415244:76415337:76415763:76416119 | 76415244:76415337 | ENSG00000136153.15 | ENST00000377499.5,ENST00000465261.2,ENST00000526202.1,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000525914.1,ENST00000447038.1 |
| exon_skip_100824 | 13 | 76416986:76417052:76419462:76419515:76423214:76423428 | 76419462:76419515 | ENSG00000136153.15 | ENST00000465261.2,ENST00000526202.1,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3 |
| exon_skip_100829 | 13 | 76427227:76427524:76429395:76429504:76430641:76430744 | 76429395:76429504 | ENSG00000136153.15 | ENST00000482116.1,ENST00000526202.1,ENST00000321797.8,ENST00000341547.4 |
| exon_skip_100831 | 13 | 76427227:76427524:76430641:76430744:76432056:76434004 | 76430641:76430744 | ENSG00000136153.15 | ENST00000465261.2,ENST00000357063.3 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for LMO7 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_100767 | 13 | 76194569:76196004:76197406:76197456:76287317:76287388 | 76197406:76197456 | ENSG00000136153.15 | ENST00000357063.3,ENST00000377534.3 |
| exon_skip_100773 | 13 | 76209945:76210026:76287317:76287388:76301164:76301234 | 76287317:76287388 | ENSG00000136153.15 | ENST00000533305.1 |
| exon_skip_100785 | 13 | 76210791:76210862:76287317:76287388:76301164:76301234 | 76287317:76287388 | ENSG00000136153.15 | ENST00000377499.5 |
| exon_skip_100793 | 13 | 76287317:76287388:76301164:76301234:76335067:76335174 | 76301164:76301234 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000533305.1,ENST00000377499.5 |
| exon_skip_100796 | 13 | 76301164:76301234:76335067:76335174:76369536:76369567 | 76335067:76335174 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000533305.1,ENST00000377499.5 |
| exon_skip_100799 | 13 | 76335067:76335174:76369536:76369567:76370771:76370885 | 76369536:76369567 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000533305.1,ENST00000377499.5,ENST00000534657.1,ENST00000321797.8,ENST00000465309.2,ENST00000526202.1,ENST00000465261.2 |
| exon_skip_100805 | 13 | 76378455:76378677:76379614:76379896:76381615:76381823 | 76379614:76379896 | ENSG00000136153.15 | ENST00000357063.3,ENST00000377534.3,ENST00000321797.8,ENST00000465261.2 |
| exon_skip_100809 | 13 | 76378455:76378677:76381615:76382335:76383289:76383319 | 76381615:76382335 | ENSG00000136153.15 | ENST00000447038.1 |
| exon_skip_100811 | 13 | 76378455:76378677:76383289:76383319:76391296:76391414 | 76383289:76383319 | ENSG00000136153.15 | ENST00000341547.4,ENST00000377499.5,ENST00000497947.2,ENST00000489941.2 |
| exon_skip_100816 | 13 | 76393528:76393671:76395312:76395745:76397700:76398009 | 76395312:76395745 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000377499.5,ENST00000321797.8,ENST00000526202.1,ENST00000465261.2,ENST00000447038.1 |
| exon_skip_100817 | 13 | 76397845:76398009:76407186:76407301:76408361:76408523 | 76407186:76407301 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000377499.5,ENST00000321797.8,ENST00000526202.1,ENST00000465261.2,ENST00000447038.1,ENST00000485987.1,ENST00000524651.1 |
| exon_skip_100818 | 13 | 76408434:76408523:76409287:76409475:76410532:76410593 | 76409287:76409475 | ENSG00000136153.15 | ENST00000526202.1,ENST00000485987.1,ENST00000524651.1 |
| exon_skip_100819 | 13 | 76408434:76408523:76409368:76409475:76410532:76410593 | 76409368:76409475 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000377499.5,ENST00000321797.8,ENST00000465261.2,ENST00000447038.1,ENST00000525107.2,ENST00000525914.1 |
| exon_skip_100820 | 13 | 76410532:76410593:76412275:76412332:76414220:76414246 | 76412275:76412332 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000377499.5,ENST00000321797.8,ENST00000526202.1,ENST00000465261.2,ENST00000447038.1 |
| exon_skip_100822 | 13 | 76412275:76412332:76412482:76412524:76414220:76414246 | 76412482:76412524 | ENSG00000136153.15 | ENST00000525107.2 |
| exon_skip_100823 | 13 | 76414526:76414631:76415244:76415337:76415763:76416119 | 76415244:76415337 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000377499.5,ENST00000321797.8,ENST00000526202.1,ENST00000465261.2,ENST00000447038.1,ENST00000525914.1 |
| exon_skip_100824 | 13 | 76416986:76417052:76419462:76419515:76423214:76423428 | 76419462:76419515 | ENSG00000136153.15 | ENST00000341547.4,ENST00000357063.3,ENST00000377534.3,ENST00000321797.8,ENST00000526202.1,ENST00000465261.2 |
| exon_skip_100829 | 13 | 76427227:76427524:76429395:76429504:76430641:76430744 | 76429395:76429504 | ENSG00000136153.15 | ENST00000341547.4,ENST00000321797.8,ENST00000526202.1,ENST00000482116.1 |
| exon_skip_100831 | 13 | 76427227:76427524:76430641:76430744:76432056:76434004 | 76430641:76430744 | ENSG00000136153.15 | ENST00000357063.3,ENST00000465261.2 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for LMO7 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
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Infer the effects of exon skipping event on protein functional features for LMO7 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for LMO7 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
LMO7_KIRC_exon_skip_100809_psi_boxplot.png |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_100805 | 76379615 | 76379896 | 76379775 | 76379775 | Frame_Shift_Del | C | - | p.P411fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_100809 | 76381616 | 76382335 | 76381620 | 76381620 | Frame_Shift_Del | T | - | p.F453fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_100809 | 76381616 | 76382335 | 76381636 | 76381636 | Frame_Shift_Del | C | - | p.A458fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_100809 | 76381616 | 76382335 | 76381703 | 76381703 | Frame_Shift_Del | C | - | p.G480fs |
| UCEC | TCGA-BG-A0LW-01 | exon_skip_100809 | 76381616 | 76382335 | 76382020 | 76382020 | Frame_Shift_Del | C | - | p.A534fs |
| KIRP | TCGA-IZ-A6M9-01 | exon_skip_100816 | 76395313 | 76395745 | 76395479 | 76395497 | Frame_Shift_Del | AAAGAAGATTCTACCACTT | - | p.509_515del |
| KIRP | TCGA-IZ-A6M9-01 | exon_skip_100816 | 76395313 | 76395745 | 76395479 | 76395497 | Frame_Shift_Del | AAAGAAGATTCTACCACTT | - | p.558_564del |
| KIRP | TCGA-IZ-A6M9-01 | exon_skip_100816 | 76395313 | 76395745 | 76395479 | 76395497 | Frame_Shift_Del | AAAGAAGATTCTACCACTT | - | p.K792fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_100816 | 76395313 | 76395745 | 76395695 | 76395695 | Frame_Shift_Del | C | - | p.P916fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_100818 | 76409288 | 76409475 | 76409382 | 76409382 | Frame_Shift_Del | A | - | p.T1132fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_100819 | 76409369 | 76409475 | 76409382 | 76409382 | Frame_Shift_Del | A | - | p.T1132fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_100820 | 76412276 | 76412332 | 76412318 | 76412318 | Frame_Shift_Del | A | - | p.Q1198fs |
| UCEC | TCGA-BS-A0UM-01 | exon_skip_100823 | 76415245 | 76415337 | 76415307 | 76415308 | Frame_Shift_Del | AG | - | p.N986fs |
| KIRC | TCGA-B0-5691-01 | exon_skip_100809 | 76381616 | 76382335 | 76381790 | 76381791 | Frame_Shift_Ins | - | T | p.D224fs |
| LGG | TCGA-DU-6392-01 | exon_skip_100773 exon_skip_100785 | 76287318 | 76287388 | 76287327 | 76287327 | Nonsense_Mutation | G | T | p.E79* |
| BLCA | TCGA-DK-A3IU-01 | exon_skip_100796 | 76335068 | 76335174 | 76335156 | 76335156 | Nonsense_Mutation | C | G | p.S152* |
| PAAD | TCGA-2J-AABO-01 | exon_skip_100805 | 76379615 | 76379896 | 76379654 | 76379654 | Nonsense_Mutation | G | A | p.W85* |
| COAD | TCGA-F4-6857-01 | exon_skip_100805 | 76379615 | 76379896 | 76379872 | 76379872 | Nonsense_Mutation | G | A | p.W158X |
| GBM | TCGA-14-1034-02 | exon_skip_100809 | 76381616 | 76382335 | 76381854 | 76381854 | Nonsense_Mutation | C | T | p.R479* |
| UCEC | TCGA-D1-A17Q-01 | exon_skip_100809 | 76381616 | 76382335 | 76382124 | 76382124 | Nonsense_Mutation | G | T | p.E336* |
| THYM | TCGA-3G-AB19-01 | exon_skip_100816 | 76395313 | 76395745 | 76395392 | 76395392 | Nonsense_Mutation | C | T | p.R530X |
| CESC | TCGA-EK-A2PG-01 | exon_skip_100816 | 76395313 | 76395745 | 76395533 | 76395533 | Nonsense_Mutation | C | T | p.Q862* |
| CESC | TCGA-EK-A3GK-01 | exon_skip_100816 | 76395313 | 76395745 | 76395627 | 76395627 | Nonsense_Mutation | C | G | p.S893* |
| SARC | TCGA-IE-A6BZ-01 | exon_skip_100816 | 76395313 | 76395745 | 76395653 | 76395653 | Nonsense_Mutation | A | T | p.K902* |
| LUAD | TCGA-69-7979-01 | exon_skip_100831 | 76430642 | 76430744 | 76430679 | 76430679 | Nonsense_Mutation | C | T | p.Q1619* |
| STAD | TCGA-CD-A4MI-01 | exon_skip_100817 | 76407187 | 76407301 | 76407186 | 76407186 | Splice_Site | G | T | p.D751_splice |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-14-1034-02 |
| Cancer type: GBM | |
| ESID: exon_skip_100809 | |
| Skipped exon start: 76381616 | |
| Skipped exon end: 76382335 | |
| Mutation start: 76381854 | |
| Mutation end: 76381854 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.R479* | |
exon_skip_100809_GBM_TCGA-14-1034-02.png | |
 | Sample: TCGA-B0-5691-01 |
| Cancer type: KIRC | |
| ESID: exon_skip_100809 | |
| Skipped exon start: 76381616 | |
| Skipped exon end: 76382335 | |
| Mutation start: 76381790 | |
| Mutation end: 76381791 | |
| Mutation type: Frame_Shift_Ins | |
| Reference seq: - | |
| Mutation seq: T | |
| AAchange: p.D224fs | |
exon_skip_100809_KIRC_TCGA-B0-5691-01.png | |
 | Sample: TCGA-DD-A1EG-01 |
| Cancer type: LIHC | |
| ESID: exon_skip_100809 | |
| Skipped exon start: 76381616 | |
| Skipped exon end: 76382335 | |
| Mutation start: 76381703 | |
| Mutation end: 76381703 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: C | |
| Mutation seq: - | |
| AAchange: p.G480fs | |
| Sample: TCGA-DD-A1EG-01 |
| Cancer type: LIHC | |
| ESID: exon_skip_100820 | |
| Skipped exon start: 76412276 | |
| Skipped exon end: 76412332 | |
| Mutation start: 76412318 | |
| Mutation end: 76412318 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: A | |
| Mutation seq: - | |
| AAchange: p.Q1198fs | |
exon_skip_103075_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_100809_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_101656_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_10700_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_109033_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_110000_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_110381_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_110545_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_11218_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_11256_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_11259_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_11263_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_115462_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_115587_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_116330_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_121002_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_123667_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_12440_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_125045_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_129202_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_129996_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_130099_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_13071_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_131505_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_131697_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_133542_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_133548_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_134792_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_135418_LIHC_TCGA-DD-A1EG-01.png | |
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 | Sample: TCGA-BG-A0LW-01 |
| Cancer type: UCEC | |
| ESID: exon_skip_100809 | |
| Skipped exon start: 76381616 | |
| Skipped exon end: 76382335 | |
| Mutation start: 76382020 | |
| Mutation end: 76382020 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: C | |
| Mutation seq: - | |
| AAchange: p.A534fs | |
exon_skip_100809_UCEC_TCGA-BG-A0LW-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SNU349_KIDNEY | 76287318 | 76287388 | 76287344 | 76287345 | Frame_Shift_Del | AA | - | p.K85fs |
| IM95_STOMACH | 76335068 | 76335174 | 76335126 | 76335126 | Frame_Shift_Del | T | - | p.L142fs |
| KCL22_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 76369537 | 76369567 | 76369561 | 76369562 | Frame_Shift_Ins | - | A | p.K167fs |
| CAL29_URINARY_TRACT | 76430642 | 76430744 | 76430705 | 76430710 | In_Frame_Del | CACCAA | - | p.HQ1379del |
| UMUC3_URINARY_TRACT | 76197407 | 76197456 | 76197410 | 76197410 | Missense_Mutation | T | C | p.I60T |
| NCIH2228_LUNG | 76197407 | 76197456 | 76197434 | 76197434 | Missense_Mutation | C | T | p.S68L |
| LS411N_LARGE_INTESTINE | 76197407 | 76197456 | 76197436 | 76197436 | Missense_Mutation | G | A | p.G69R |
| CHSA8926_BONE | 76335068 | 76335174 | 76335075 | 76335075 | Missense_Mutation | T | C | p.I125T |
| ISTMEL1_SKIN | 76369537 | 76369567 | 76369562 | 76369562 | Missense_Mutation | A | C | p.K167Q |
| GP2D_LARGE_INTESTINE | 76379615 | 76379896 | 76379626 | 76379626 | Missense_Mutation | G | T | p.R76M |
| GP5D_LARGE_INTESTINE | 76379615 | 76379896 | 76379626 | 76379626 | Missense_Mutation | G | T | p.R76M |
| OC316_OVARY | 76379615 | 76379896 | 76379635 | 76379635 | Missense_Mutation | G | T | p.G79V |
| OC314_OVARY | 76379615 | 76379896 | 76379635 | 76379635 | Missense_Mutation | G | T | p.G79V |
| UMC11_LUNG | 76379615 | 76379896 | 76379641 | 76379641 | Missense_Mutation | A | G | p.N81S |
| SNU1040_LARGE_INTESTINE | 76379615 | 76379896 | 76379695 | 76379695 | Missense_Mutation | A | G | p.E99G |
| SISO_CERVIX | 76379615 | 76379896 | 76379739 | 76379739 | Missense_Mutation | G | C | p.D114H |
| GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 76379615 | 76379896 | 76379739 | 76379739 | Missense_Mutation | G | C | p.D114H |
| EFO27_OVARY | 76379615 | 76379896 | 76379751 | 76379751 | Missense_Mutation | G | A | p.V118M |
| C32_SKIN | 76379615 | 76379896 | 76379754 | 76379754 | Missense_Mutation | C | T | p.R119C |
| JEKO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 76379615 | 76379896 | 76379796 | 76379796 | Missense_Mutation | G | A | p.D133N |
| D425_CENTRAL_NERVOUS_SYSTEM | 76379615 | 76379896 | 76379851 | 76379851 | Missense_Mutation | A | G | p.K151R |
| A375_SKIN | 76379615 | 76379896 | 76379875 | 76379875 | Missense_Mutation | A | G | p.Y159C |
| KYSE30_OESOPHAGUS | 76379615 | 76379896 | 76379879 | 76379879 | Missense_Mutation | A | T | p.K160N |
| VMCUB1_URINARY_TRACT | 76381616 | 76382335 | 76381658 | 76381658 | Missense_Mutation | C | G | p.D180E |
| A3KAW_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 76381616 | 76382335 | 76381664 | 76381664 | Missense_Mutation | G | C | p.L182F |
| HEC251_ENDOMETRIUM | 76381616 | 76382335 | 76381666 | 76381666 | Missense_Mutation | C | A | p.S183Y |
| SKGT2_STOMACH | 76381616 | 76382335 | 76381771 | 76381771 | Missense_Mutation | T | C | p.M218T |
| TO175T_FIBROBLAST | 76381616 | 76382335 | 76381827 | 76381827 | Missense_Mutation | G | A | p.A237T |
| MLMA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 76381616 | 76382335 | 76381884 | 76381884 | Missense_Mutation | G | A | p.E256K |
| OVK18_OVARY | 76381616 | 76382335 | 76381977 | 76381977 | Missense_Mutation | C | T | p.R287C |
| M980513_SKIN | 76381616 | 76382335 | 76381981 | 76381981 | Missense_Mutation | G | A | p.R288Q |
| SNU1040_LARGE_INTESTINE | 76381616 | 76382335 | 76382131 | 76382131 | Missense_Mutation | G | A | p.S338N |
| SKUT1_SOFT_TISSUE | 76381616 | 76382335 | 76382210 | 76382210 | Missense_Mutation | A | T | p.K364N |
| LNCAPCLONEFGC_PROSTATE | 76381616 | 76382335 | 76382254 | 76382254 | Missense_Mutation | G | A | p.C379Y |
| CAL39_VULVA | 76383290 | 76383319 | 76383309 | 76383309 | Missense_Mutation | G | A | p.G413S |
| JHUEM7_ENDOMETRIUM | 76395313 | 76395745 | 76395515 | 76395515 | Missense_Mutation | C | T | p.R571C |
| LNZ308_CENTRAL_NERVOUS_SYSTEM | 76395313 | 76395745 | 76395530 | 76395530 | Missense_Mutation | A | G | p.I576V |
| CHP134_AUTONOMIC_GANGLIA | 76395313 | 76395745 | 76395596 | 76395596 | Missense_Mutation | C | T | p.R598W |
| NCIH2342_LUNG | 76395313 | 76395745 | 76395705 | 76395705 | Missense_Mutation | C | T | p.S634F |
| SNU349_KIDNEY | 76407187 | 76407301 | 76407199 | 76407199 | Missense_Mutation | G | T | p.D755Y |
| NCIH748_LUNG | 76407187 | 76407301 | 76407218 | 76407218 | Missense_Mutation | A | T | p.N761I |
| FTC238_THYROID | 76407187 | 76407301 | 76407272 | 76407272 | Missense_Mutation | C | A | p.P779H |
| HCT15_LARGE_INTESTINE | 76409288 | 76409475 | 76409323 | 76409323 | Missense_Mutation | C | T | p.R705W |
| HCT15_LARGE_INTESTINE | 76409369 | 76409475 | 76409450 | 76409450 | Missense_Mutation | A | T | p.D870V |
| HCT15_LARGE_INTESTINE | 76409288 | 76409475 | 76409450 | 76409450 | Missense_Mutation | A | T | p.D870V |
| D245MG_CENTRAL_NERVOUS_SYSTEM | 76415245 | 76415337 | 76415258 | 76415258 | Missense_Mutation | G | A | p.R966H |
| HUCCT1_BILIARY_TRACT | 76415245 | 76415337 | 76415304 | 76415304 | Missense_Mutation | G | T | p.E981D |
| A673_BONE | 76419463 | 76419515 | 76419493 | 76419493 | Missense_Mutation | T | A | p.D1143E |
| NCIH650_LUNG | 76429396 | 76429504 | 76429436 | 76429436 | Missense_Mutation | A | T | p.I1335F |
| SNU407_LARGE_INTESTINE | 76429396 | 76429504 | 76429454 | 76429454 | Missense_Mutation | G | A | p.A1341T |
| RL952_ENDOMETRIUM | 76429396 | 76429504 | 76429473 | 76429473 | Missense_Mutation | T | C | p.L1347P |
| SNU1040_LARGE_INTESTINE | 76429396 | 76429504 | 76429493 | 76429493 | Missense_Mutation | C | T | p.H1354Y |
| LB647PBL_MATCHED_NORMAL_TISSUE | 76429396 | 76429504 | 76429494 | 76429494 | Missense_Mutation | A | G | p.H1354R |
| LB647SCLC_LUNG | 76429396 | 76429504 | 76429494 | 76429494 | Missense_Mutation | A | G | p.H1354R |
| RPMI7951_SKIN | 76430642 | 76430744 | 76430650 | 76430650 | Missense_Mutation | C | G | p.P1324R |
| EPLC272H_LUNG | 76379615 | 76379896 | 76379619 | 76379619 | Nonsense_Mutation | C | T | p.Q74* |
| SNU81_LARGE_INTESTINE | 76381616 | 76382335 | 76382124 | 76382124 | Nonsense_Mutation | G | T | p.E336* |
| JHUEM7_ENDOMETRIUM | 76430642 | 76430744 | 76430740 | 76430740 | Nonsense_Mutation | C | A | p.S1354* |
| NB1643_AUTONOMIC_GANGLIA | 76335068 | 76335174 | 76335069 | 76335069 | Splice_Site | A | G | p.D123G |
| S117_SOFT_TISSUE | 76335068 | 76335174 | 76335069 | 76335069 | Splice_Site | A | G | p.D123G |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for LMO7 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_100819 | 13 | 76408434:76408523:76409368:76409475:76410532:76410593 | 76409368:76409475 | ENST00000377499.5,ENST00000465261.2,ENST00000525107.2,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000525914.1,ENST00000447038.1 | KIRC | rs2273997 | chr13:76409436 | A/G | 4.41e-06 |
| exon_skip_100819 | 13 | 76408434:76408523:76409368:76409475:76410532:76410593 | 76409368:76409475 | ENST00000377499.5,ENST00000465261.2,ENST00000525107.2,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000525914.1,ENST00000447038.1 | LUSC | rs2273997 | chr13:76409436 | A/G | 6.26e-07 |
| exon_skip_100816 | 13 | 76393528:76393671:76395312:76395745:76397700:76398009 | 76395312:76395745 | ENST00000377499.5,ENST00000465261.2,ENST00000526202.1,ENST00000321797.8,ENST00000377534.3,ENST00000341547.4,ENST00000357063.3,ENST00000447038.1 | PRAD | rs41286126 | chr13:76395464 | C/T | 3.94e-04 |
| exon_skip_100818 | 13 | 76408434:76408523:76409287:76409475:76410532:76410593 | 76409287:76409475 | ENST00000524651.1,ENST00000526202.1,ENST00000485987.1 | KIRC | rs2273997 | chr13:76409436 | A/G | 4.41e-06 |
| exon_skip_100818 | 13 | 76408434:76408523:76409287:76409475:76410532:76410593 | 76409287:76409475 | ENST00000524651.1,ENST00000526202.1,ENST00000485987.1 | LUSC | rs2273997 | chr13:76409436 | A/G | 6.26e-07 |
| exon_skip_100809 | 13 | 76378455:76378677:76381615:76382335:76383289:76383319 | 76381615:76382335 | ENST00000447038.1 | KIRC | rs2241913 | chr13:76382100 | C/T | 1.90e-03 |
| exon_skip_100809 | 13 | 76378455:76378677:76381615:76382335:76383289:76383319 | 76381615:76382335 | ENST00000447038.1 | LUAD | rs2241913 | chr13:76382100 | C/T | 2.38e-03 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for LMO7 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for LMO7 |
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RelatedDrugs for LMO7 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LMO7 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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