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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for STT3A |
 Gene summary |
| Gene information | Gene symbol | STT3A | Gene ID | 3703 |
| Gene name | STT3A, catalytic subunit of the oligosaccharyltransferase complex | |
| Synonyms | ITM1|STT3-A|TMC | |
| Cytomap | 11q24.2 | |
| Type of gene | protein-coding | |
| Description | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3AB5STT3, subunit of the oligosaccharyltransferase complex, homolog ASTT3A, cataylic subunit of the oligosaccharyltransferase complexSTT3A, subunit of the oligosaccharyltransfer | |
| Modification date | 20180522 | |
| UniProtAcc | P46977 | |
| Context | PubMed: STT3A [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for STT3A from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for STT3A |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for STT3A |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_66373 | 11 | 125462761:125462813:125463532:125463620:125465775:125465898 | 125463532:125463620 | ENSG00000134910.8 | ENST00000529196.1 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENSG00000134910.8 | ENST00000534472.1,ENST00000392708.4 |
| exon_skip_66378 | 11 | 125462761:125462813:125466953:125467014:125472197:125472319 | 125466953:125467014 | ENSG00000134910.8 | ENST00000531491.1 |
| exon_skip_66386 | 11 | 125465775:125465898:125466953:125467014:125472197:125472319 | 125466953:125467014 | ENSG00000134910.8 | ENST00000529886.1,ENST00000534472.1,ENST00000525652.1,ENST00000529196.1,ENST00000392708.4,ENST00000527606.1 |
| exon_skip_66387 | 11 | 125472197:125472319:125472697:125472843:125474051:125474142 | 125472697:125472843 | ENSG00000134910.8 | ENST00000531491.1,ENST00000534472.1,ENST00000529196.1,ENST00000392708.4 |
| exon_skip_66388 | 11 | 125474051:125474142:125475523:125475630:125476195:125476360 | 125475523:125475630 | ENSG00000134910.8 | ENST00000531491.1,ENST00000526213.1,ENST00000534472.1,ENST00000527456.1,ENST00000529196.1,ENST00000392708.4 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENSG00000134910.8 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 |
| exon_skip_66392 | 11 | 125479328:125479484:125481322:125481414:125482486:125482642 | 125481322:125481414 | ENSG00000134910.8 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000524639.1 |
| exon_skip_66394 | 11 | 125479328:125479484:125482486:125482642:125482883:125482965 | 125482486:125482642 | ENSG00000134910.8 | ENST00000526726.1 |
| exon_skip_66398 | 11 | 125481322:125481414:125482486:125482642:125482883:125482965 | 125482486:125482642 | ENSG00000134910.8 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000524639.1 |
| exon_skip_66400 | 11 | 125482883:125483072:125483981:125484098:125484218:125484321 | 125483981:125484098 | ENSG00000134910.8 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENSG00000134910.8 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 |
| exon_skip_66407 | 11 | 125489905:125490021:125491300:125491414:125494767:125495110 | 125491300:125491414 | ENSG00000134910.8 | ENST00000526364.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for STT3A |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_66373 | 11 | 125462761:125462813:125463532:125463620:125465775:125465898 | 125463532:125463620 | ENSG00000134910.8 | ENST00000529196.1 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENSG00000134910.8 | ENST00000392708.4,ENST00000534472.1 |
| exon_skip_66378 | 11 | 125462761:125462813:125466953:125467014:125472197:125472319 | 125466953:125467014 | ENSG00000134910.8 | ENST00000531491.1 |
| exon_skip_66386 | 11 | 125465775:125465898:125466953:125467014:125472197:125472319 | 125466953:125467014 | ENSG00000134910.8 | ENST00000527606.1,ENST00000392708.4,ENST00000534472.1,ENST00000529196.1,ENST00000525652.1,ENST00000529886.1 |
| exon_skip_66387 | 11 | 125472197:125472319:125472697:125472843:125474051:125474142 | 125472697:125472843 | ENSG00000134910.8 | ENST00000392708.4,ENST00000534472.1,ENST00000529196.1,ENST00000531491.1 |
| exon_skip_66388 | 11 | 125474051:125474142:125475523:125475630:125476195:125476360 | 125475523:125475630 | ENSG00000134910.8 | ENST00000392708.4,ENST00000534472.1,ENST00000529196.1,ENST00000531491.1,ENST00000526213.1,ENST00000527456.1 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENSG00000134910.8 | ENST00000392708.4,ENST00000529196.1,ENST00000531491.1 |
| exon_skip_66392 | 11 | 125479328:125479484:125481322:125481414:125482486:125482642 | 125481322:125481414 | ENSG00000134910.8 | ENST00000392708.4,ENST00000529196.1,ENST00000531491.1,ENST00000524639.1 |
| exon_skip_66394 | 11 | 125479328:125479484:125482486:125482642:125482883:125482965 | 125482486:125482642 | ENSG00000134910.8 | ENST00000526726.1 |
| exon_skip_66398 | 11 | 125481322:125481414:125482486:125482642:125482883:125482965 | 125482486:125482642 | ENSG00000134910.8 | ENST00000392708.4,ENST00000529196.1,ENST00000531491.1,ENST00000524639.1 |
| exon_skip_66400 | 11 | 125482883:125483072:125483981:125484098:125484218:125484321 | 125483981:125484098 | ENSG00000134910.8 | ENST00000392708.4,ENST00000529196.1,ENST00000531491.1 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENSG00000134910.8 | ENST00000392708.4,ENST00000529196.1,ENST00000531491.1,ENST00000525946.1 |
| exon_skip_66407 | 11 | 125489905:125490021:125491300:125491414:125494767:125495110 | 125491300:125491414 | ENSG00000134910.8 | ENST00000526364.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for STT3A |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000392708 | 125465775 | 125465898 | 5CDS-5UTR |
| ENST00000529196 | 125463532 | 125463620 | 5UTR-5UTR |
| ENST00000392708 | 125466953 | 125467014 | Frame-shift |
| ENST00000529196 | 125466953 | 125467014 | Frame-shift |
| ENST00000392708 | 125472697 | 125472843 | Frame-shift |
| ENST00000529196 | 125472697 | 125472843 | Frame-shift |
| ENST00000392708 | 125475523 | 125475630 | Frame-shift |
| ENST00000529196 | 125475523 | 125475630 | Frame-shift |
| ENST00000392708 | 125481322 | 125481414 | Frame-shift |
| ENST00000529196 | 125481322 | 125481414 | Frame-shift |
| ENST00000392708 | 125479328 | 125479484 | In-frame |
| ENST00000529196 | 125479328 | 125479484 | In-frame |
| ENST00000392708 | 125482486 | 125482642 | In-frame |
| ENST00000529196 | 125482486 | 125482642 | In-frame |
| ENST00000392708 | 125483981 | 125484098 | In-frame |
| ENST00000529196 | 125483981 | 125484098 | In-frame |
| ENST00000392708 | 125488267 | 125488456 | In-frame |
| ENST00000529196 | 125488267 | 125488456 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000392708 | 125465775 | 125465898 | 5CDS-5UTR |
| ENST00000529196 | 125463532 | 125463620 | 5UTR-5UTR |
| ENST00000392708 | 125466953 | 125467014 | Frame-shift |
| ENST00000529196 | 125466953 | 125467014 | Frame-shift |
| ENST00000392708 | 125472697 | 125472843 | Frame-shift |
| ENST00000529196 | 125472697 | 125472843 | Frame-shift |
| ENST00000392708 | 125475523 | 125475630 | Frame-shift |
| ENST00000529196 | 125475523 | 125475630 | Frame-shift |
| ENST00000392708 | 125481322 | 125481414 | Frame-shift |
| ENST00000529196 | 125481322 | 125481414 | Frame-shift |
| ENST00000392708 | 125479328 | 125479484 | In-frame |
| ENST00000529196 | 125479328 | 125479484 | In-frame |
| ENST00000392708 | 125482486 | 125482642 | In-frame |
| ENST00000529196 | 125482486 | 125482642 | In-frame |
| ENST00000392708 | 125483981 | 125484098 | In-frame |
| ENST00000529196 | 125483981 | 125484098 | In-frame |
| ENST00000392708 | 125488267 | 125488456 | In-frame |
| ENST00000529196 | 125488267 | 125488456 | In-frame |
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Infer the effects of exon skipping event on protein functional features for STT3A |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000392708 | 4575 | 705 | 125479328 | 125479484 | 1121 | 1276 | 320 | 372 |
| ENST00000529196 | 2419 | 705 | 125479328 | 125479484 | 1168 | 1323 | 320 | 372 |
| ENST00000392708 | 4575 | 705 | 125482486 | 125482642 | 1369 | 1524 | 403 | 455 |
| ENST00000529196 | 2419 | 705 | 125482486 | 125482642 | 1416 | 1571 | 403 | 455 |
| ENST00000392708 | 4575 | 705 | 125483981 | 125484098 | 1714 | 1830 | 518 | 557 |
| ENST00000529196 | 2419 | 705 | 125483981 | 125484098 | 1761 | 1877 | 518 | 557 |
| ENST00000392708 | 4575 | 705 | 125488267 | 125488456 | 1934 | 2122 | 591 | 654 |
| ENST00000529196 | 2419 | 705 | 125488267 | 125488456 | 1981 | 2169 | 591 | 654 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000392708 | 4575 | 705 | 125479328 | 125479484 | 1121 | 1276 | 320 | 372 |
| ENST00000529196 | 2419 | 705 | 125479328 | 125479484 | 1168 | 1323 | 320 | 372 |
| ENST00000392708 | 4575 | 705 | 125482486 | 125482642 | 1369 | 1524 | 403 | 455 |
| ENST00000529196 | 2419 | 705 | 125482486 | 125482642 | 1416 | 1571 | 403 | 455 |
| ENST00000392708 | 4575 | 705 | 125483981 | 125484098 | 1714 | 1830 | 518 | 557 |
| ENST00000529196 | 2419 | 705 | 125483981 | 125484098 | 1761 | 1877 | 518 | 557 |
| ENST00000392708 | 4575 | 705 | 125488267 | 125488456 | 1934 | 2122 | 591 | 654 |
| ENST00000529196 | 2419 | 705 | 125488267 | 125488456 | 1981 | 2169 | 591 | 654 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| P46977 | 320 | 372 | 351 | 351 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 320 | 372 | 351 | 351 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 320 | 372 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 320 | 372 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 320 | 372 | 348 | 351 | Motif | Note=SVSE motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q5HTX9 |
| P46977 | 320 | 372 | 348 | 351 | Motif | Note=SVSE motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q5HTX9 |
| P46977 | 320 | 372 | 322 | 356 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 320 | 372 | 322 | 356 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 320 | 372 | 301 | 321 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| P46977 | 320 | 372 | 301 | 321 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| P46977 | 320 | 372 | 357 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 320 | 372 | 357 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 405 | 405 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 403 | 455 | 405 | 405 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 403 | 455 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 403 | 455 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 403 | 455 | 415 | 415 | Sequence conflict | Note=C->S;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 415 | 415 | Sequence conflict | Note=C->S;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 454 | 454 | Sequence conflict | Note=N->I;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 454 | 454 | Sequence conflict | Note=N->I;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 403 | 406 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 403 | 406 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 429 | 453 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 429 | 453 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 407 | 428 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 407 | 428 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 454 | 473 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 454 | 473 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 518 | 557 | 530 | 530 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 530 | 530 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 518 | 557 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 518 | 557 | 537 | 537 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 537 | 537 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 544 | 544 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 544 | 544 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 548 | 548 | Glycosylation | Note=N-linked (GlcNAc...) (high mannose) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 548 | 548 | Glycosylation | Note=N-linked (GlcNAc...) (high mannose) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 525 | 529 | Motif | Note=WWDYG motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 518 | 557 | 525 | 529 | Motif | Note=WWDYG motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 518 | 557 | 525 | 527 | Region | Note=Target acceptor peptide binding;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 525 | 527 | Region | Note=Target acceptor peptide binding;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 518 | 557 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 591 | 654 | 595 | 595 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 591 | 654 | 595 | 595 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 591 | 654 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 591 | 654 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 591 | 654 | 592 | 599 | Motif | Note=DK motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 591 | 654 | 592 | 599 | Motif | Note=DK motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 591 | 654 | 626 | 626 | Natural variant | ID=VAR_070944;Note=In CDG1W%3B affects activity resulting in hypoglycosylation of STT3A-specific substrates. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23842455;Dbxref=dbSNP:rs587777216,PMID:23842455 |
| P46977 | 591 | 654 | 626 | 626 | Natural variant | ID=VAR_070944;Note=In CDG1W%3B affects activity resulting in hypoglycosylation of STT3A-specific substrates. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23842455;Dbxref=dbSNP:rs587777216,PMID:23842455 |
| P46977 | 591 | 654 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 591 | 654 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| P46977 | 320 | 372 | 351 | 351 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 320 | 372 | 351 | 351 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 320 | 372 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 320 | 372 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 320 | 372 | 348 | 351 | Motif | Note=SVSE motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q5HTX9 |
| P46977 | 320 | 372 | 348 | 351 | Motif | Note=SVSE motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q5HTX9 |
| P46977 | 320 | 372 | 322 | 356 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 320 | 372 | 322 | 356 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 320 | 372 | 301 | 321 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| P46977 | 320 | 372 | 301 | 321 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| P46977 | 320 | 372 | 357 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 320 | 372 | 357 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 405 | 405 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 403 | 455 | 405 | 405 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 403 | 455 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 403 | 455 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 403 | 455 | 415 | 415 | Sequence conflict | Note=C->S;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 415 | 415 | Sequence conflict | Note=C->S;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 454 | 454 | Sequence conflict | Note=N->I;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 454 | 454 | Sequence conflict | Note=N->I;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 403 | 406 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 403 | 406 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 429 | 453 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 429 | 453 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 403 | 455 | 407 | 428 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 407 | 428 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 454 | 473 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 403 | 455 | 454 | 473 | Transmembrane | Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 518 | 557 | 530 | 530 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 530 | 530 | Binding site | Note=Lipid-linked oligosaccharide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 518 | 557 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 518 | 557 | 537 | 537 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 537 | 537 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 544 | 544 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 544 | 544 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 548 | 548 | Glycosylation | Note=N-linked (GlcNAc...) (high mannose) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 548 | 548 | Glycosylation | Note=N-linked (GlcNAc...) (high mannose) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P46977 | 518 | 557 | 525 | 529 | Motif | Note=WWDYG motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 518 | 557 | 525 | 529 | Motif | Note=WWDYG motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 518 | 557 | 525 | 527 | Region | Note=Target acceptor peptide binding;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 525 | 527 | Region | Note=Target acceptor peptide binding;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 518 | 557 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 518 | 557 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 591 | 654 | 595 | 595 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 591 | 654 | 595 | 595 | Binding site | Note=Target acceptor peptide;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:B9KDD4 |
| P46977 | 591 | 654 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 591 | 654 | 1 | 705 | Chain | ID=PRO_0000072290;Note=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A |
| P46977 | 591 | 654 | 592 | 599 | Motif | Note=DK motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 591 | 654 | 592 | 599 | Motif | Note=DK motif;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P39007 |
| P46977 | 591 | 654 | 626 | 626 | Natural variant | ID=VAR_070944;Note=In CDG1W%3B affects activity resulting in hypoglycosylation of STT3A-specific substrates. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23842455;Dbxref=dbSNP:rs587777216,PMID:23842455 |
| P46977 | 591 | 654 | 626 | 626 | Natural variant | ID=VAR_070944;Note=In CDG1W%3B affects activity resulting in hypoglycosylation of STT3A-specific substrates. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23842455;Dbxref=dbSNP:rs587777216,PMID:23842455 |
| P46977 | 591 | 654 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| P46977 | 591 | 654 | 474 | 705 | Topological domain | Note=Lumenal;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
Top |
SNVs in the skipped exons for STT3A |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
 |
| - Differential PSIs between mutated versus non-mutated samples. |
STT3A_LIHC_exon_skip_66376_psi_boxplot.png |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_66376 | 125465776 | 125465898 | 125465826 | 125465826 | Frame_Shift_Del | T | - | p.F6fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_66376 | 125465776 | 125465898 | 125465860 | 125465860 | Frame_Shift_Del | T | - | p.L18fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_66387 | 125472698 | 125472843 | 125472738 | 125472738 | Frame_Shift_Del | T | - | p.H104fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_66404 | 125488268 | 125488456 | 125488344 | 125488344 | Frame_Shift_Del | T | - | p.Y618fs |
| KIRC | TCGA-B0-5709-01 | exon_skip_66389 | 125479329 | 125479484 | 125479362 | 125479362 | Nonsense_Mutation | C | A | p.S332X |
| COAD | TCGA-AA-A01Q-01 | exon_skip_66400 | 125483982 | 125484098 | 125484067 | 125484067 | Nonsense_Mutation | G | A | p.W547X |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-DD-A1EG-01 |
| Cancer type: LIHC | |
| ESID: exon_skip_66376 | |
| Skipped exon start: 125465776 | |
| Skipped exon end: 125465898 | |
| Mutation start: 125465860 | |
| Mutation end: 125465860 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: T | |
| Mutation seq: - | |
| AAchange: p.L18fs | |
| Sample: TCGA-DD-A1EG-01 |
| Cancer type: LIHC | |
| ESID: exon_skip_66404 | |
| Skipped exon start: 125488268 | |
| Skipped exon end: 125488456 | |
| Mutation start: 125488344 | |
| Mutation end: 125488344 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: T | |
| Mutation seq: - | |
| AAchange: p.Y618fs | |
exon_skip_103075_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_100809_LIHC_TCGA-DD-A1EG-01.png | |
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exon_skip_307291_LIHC_TCGA-DD-A1EG-01.png | |
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exon_skip_30744_LIHC_TCGA-DD-A1EG-01.png | |
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exon_skip_309505_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_309539_LIHC_TCGA-DD-A1EG-01.png | |
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exon_skip_32002_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_320793_LIHC_TCGA-DD-A1EG-01.png | |
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exon_skip_320805_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_320820_LIHC_TCGA-DD-A1EG-01.png | |
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exon_skip_358435_LIHC_TCGA-DD-A1EG-01.png | |
exon_skip_359435_LIHC_TCGA-DD-A1EG-01.png | |
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| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 125465776 | 125465898 | 125465820 | 125465820 | Missense_Mutation | T | C | p.F4L |
| BICR10_UPPER_AERODIGESTIVE_TRACT | 125472698 | 125472843 | 125472705 | 125472705 | Missense_Mutation | G | A | p.M93I |
| C33A_CERVIX | 125472698 | 125472843 | 125472773 | 125472773 | Missense_Mutation | G | C | p.C116S |
| HS940T_FIBROBLAST | 125475524 | 125475630 | 125475545 | 125475545 | Missense_Mutation | T | C | p.L177P |
| CAL148_BREAST | 125479329 | 125479484 | 125479479 | 125479479 | Missense_Mutation | T | G | p.F371C |
| HS822T_FIBROBLAST | 125481323 | 125481414 | 125481376 | 125481376 | Missense_Mutation | A | G | p.M391V |
| SNU1040_LARGE_INTESTINE | 125481323 | 125481414 | 125481403 | 125481403 | Missense_Mutation | T | C | p.S400P |
| NCIH2286_LUNG | 125482487 | 125482642 | 125482640 | 125482640 | Missense_Mutation | G | A | p.E455K |
| MDAMB231_BREAST | 125483982 | 125484098 | 125483994 | 125483994 | Missense_Mutation | A | T | p.M523L |
| SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 125483982 | 125484098 | 125484007 | 125484007 | Missense_Mutation | A | G | p.D527G |
| NY_BONE | 125483982 | 125484098 | 125484036 | 125484036 | Missense_Mutation | A | G | p.N537D |
| MZ7MEL_SKIN | 125488268 | 125488456 | 125488301 | 125488301 | Missense_Mutation | G | A | p.G603E |
| HPBALL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 125488268 | 125488456 | 125488430 | 125488430 | Missense_Mutation | G | A | p.R646H |
| HEC59_ENDOMETRIUM | 125465776 | 125465898 | 125465832 | 125465832 | Nonsense_Mutation | C | T | p.R8* |
| LNCAPCLONEFGC_PROSTATE | 125483982 | 125484098 | 125484002 | 125484002 | Nonsense_Mutation | G | A | p.W525* |
| BT474_BREAST | 125483982 | 125484098 | 125484018 | 125484018 | Nonsense_Mutation | C | T | p.Q531* |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 125482487 | 125482642 | 125482642 | 125482642 | Splice_Site | A | G | p.E455E |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for STT3A |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | GBM | rs17140116 | chr11:125488404 | C/T | 4.48e-04 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | COAD | rs17140116 | chr11:125488404 | C/T | 1.95e-06 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | HNSC | rs17140116 | chr11:125488404 | C/T | 1.02e-07 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | LGG | rs17140116 | chr11:125488404 | C/T | 1.07e-07 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | KIRC | rs17140116 | chr11:125488404 | C/T | 1.85e-09 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | LUAD | rs17140116 | chr11:125488404 | C/T | 2.79e-06 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | LUSC | rs17140116 | chr11:125488404 | C/T | 7.21e-07 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | PRAD | rs17140116 | chr11:125488404 | C/T | 2.19e-03 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | PRAD | rs17140116 | chr11:125488404 | C/T | 3.03e-03 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | STAD | rs17140116 | chr11:125488404 | C/T | 3.97e-04 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | THCA | rs17140116 | chr11:125488404 | C/T | 1.98e-03 |
| exon_skip_66404 | 11 | 125484218:125484321:125488267:125488456:125489905:125490021 | 125488267:125488456 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4,ENST00000525946.1 | UCEC | rs17140116 | chr11:125488404 | C/T | 3.52e-04 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | GBM | rs10082632 | chr11:125465862 | T/C | 4.57e-04 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | COAD | rs10082632 | chr11:125465862 | T/C | 1.35e-06 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | HNSC | rs10082632 | chr11:125465862 | T/C | 8.51e-07 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | LGG | rs10082632 | chr11:125465862 | T/C | 3.96e-08 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | KIRC | rs10082632 | chr11:125465862 | T/C | 1.12e-08 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | LUAD | rs10082632 | chr11:125465862 | T/C | 4.22e-07 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | LUSC | rs10082632 | chr11:125465862 | T/C | 7.30e-07 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | OV | rs10082632 | chr11:125465862 | T/C | 5.57e-07 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | PRAD | rs10082632 | chr11:125465862 | T/C | 1.11e-03 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | STAD | rs10082632 | chr11:125465862 | T/C | 2.85e-04 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | THCA | rs10082632 | chr11:125465862 | T/C | 1.11e-03 |
| exon_skip_66376 | 11 | 125462761:125462813:125465775:125465898:125466953:125467014 | 125465775:125465898 | ENST00000534472.1,ENST00000392708.4 | UCEC | rs10082632 | chr11:125465862 | T/C | 5.16e-06 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | GBM | rs2241502 | chr11:125479363 | G/A | 1.72e-05 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | COAD | rs2241502 | chr11:125479363 | G/A | 1.52e-04 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | HNSC | rs2241502 | chr11:125479363 | G/A | 9.69e-05 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | LGG | rs2241502 | chr11:125479363 | G/A | 7.59e-09 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | KIRC | rs2241502 | chr11:125479363 | G/A | 6.05e-08 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | LUAD | rs2241502 | chr11:125479363 | G/A | 2.03e-07 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | LUSC | rs2241502 | chr11:125479363 | G/A | 2.69e-09 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | PRAD | rs2241502 | chr11:125479363 | G/A | 4.16e-06 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | SARC | rs2241502 | chr11:125479363 | G/A | 3.16e-04 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | STAD | rs2241502 | chr11:125479363 | G/A | 1.60e-05 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | THCA | rs2241502 | chr11:125479363 | G/A | 3.00e-06 |
| exon_skip_66389 | 11 | 125478042:125478184:125479328:125479484:125481322:125481414 | 125479328:125479484 | ENST00000531491.1,ENST00000529196.1,ENST00000392708.4 | UCEC | rs2241502 | chr11:125479363 | G/A | 3.13e-06 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for STT3A |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for STT3A |
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RelatedDrugs for STT3A |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for STT3A |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| STT3A | C3810062 | CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iw | 1 | ORPHANET;UNIPROT |
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