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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for PRMT2

check button Gene summary
Gene informationGene symbol

PRMT2

Gene ID

3275

Gene nameprotein arginine methyltransferase 2
SynonymsHRMT1L1
Cytomap

21q22.3

Type of geneprotein-coding
Descriptionprotein arginine N-methyltransferase 2HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1HMT1 hnRNP methyltransferase-like 1PRMT2 alphaPRMT2 betaPRMT2 gammahistone-arginine N-methyltransferase PRMT2
Modification date20180523
UniProtAcc

P55345

ContextPubMed: PRMT2 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PRMT2

GO:0016571

histone methylation

19405910

PRMT2

GO:0032088

negative regulation of NF-kappaB transcription factor activity

16648481

PRMT2

GO:0045892

negative regulation of transcription, DNA-templated

16648481

PRMT2

GO:0045893

positive regulation of transcription, DNA-templated

12039952

PRMT2

GO:0060765

regulation of androgen receptor signaling pathway

17587566


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Exon skipping events across known transcript of Ensembl for PRMT2 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for PRMT2

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for PRMT2

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_3612032148068435:48068531:48069486:48069651:48078656:4807883248069486:48069651ENSG00000160310.12ENST00000451211.2,ENST00000355680.3,ENST00000481861.1,ENST00000397638.2,ENST00000397637.1,ENST00000482508.1
exon_skip_3612042148068419:48068531:48069486:48069651:48083294:4808346648069486:48069651ENSG00000160310.12ENST00000458387.2
exon_skip_3612052148068419:48068531:48069486:48069651:48084206:4808485748069486:48069651ENSG00000160310.12ENST00000291705.6
exon_skip_3612182148069486:48069651:48078656:48078832:48080744:4808087448078656:48078832ENSG00000160310.12ENST00000355680.3,ENST00000397638.2,ENST00000397637.1,ENST00000482508.1
exon_skip_3612202148069609:48069651:48078656:48078832:48084206:4808485748078656:48078832ENSG00000160310.12ENST00000451211.2
exon_skip_3612292148069609:48069651:48081711:48081848:48083294:4808346648081711:48081848ENSG00000160310.12ENST00000440086.1
exon_skip_3612352148069609:48069651:48083294:48083466:48084206:4808485748083294:48083466ENSG00000160310.12ENST00000458387.2
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENSG00000160310.12ENST00000486520.1
exon_skip_3612472148080744:48080874:48081711:48081848:48083294:4808346648081711:48081848ENSG00000160310.12ENST00000355680.3,ENST00000397638.2,ENST00000397637.1
exon_skip_3612532148081711:48081848:48083294:48083466:48084206:4808485748083294:48083466ENSG00000160310.12ENST00000440086.1,ENST00000486520.1,ENST00000355680.3,ENST00000397638.2,ENST00000397637.1

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for PRMT2

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_3612032148068435:48068531:48069486:48069651:48078656:4807883248069486:48069651ENSG00000160310.12ENST00000355680.3,ENST00000397638.2,ENST00000451211.2,ENST00000397637.1,ENST00000482508.1,ENST00000481861.1
exon_skip_3612042148068419:48068531:48069486:48069651:48083294:4808346648069486:48069651ENSG00000160310.12ENST00000458387.2
exon_skip_3612052148068419:48068531:48069486:48069651:48084206:4808485748069486:48069651ENSG00000160310.12ENST00000291705.6
exon_skip_3612182148069486:48069651:48078656:48078832:48080744:4808087448078656:48078832ENSG00000160310.12ENST00000355680.3,ENST00000397638.2,ENST00000397637.1,ENST00000482508.1
exon_skip_3612202148069609:48069651:48078656:48078832:48084206:4808485748078656:48078832ENSG00000160310.12ENST00000451211.2
exon_skip_3612292148069609:48069651:48081711:48081848:48083294:4808346648081711:48081848ENSG00000160310.12ENST00000440086.1
exon_skip_3612352148069609:48069651:48083294:48083466:48084206:4808485748083294:48083466ENSG00000160310.12ENST00000458387.2
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENSG00000160310.12ENST00000486520.1
exon_skip_3612472148080744:48080874:48081711:48081848:48083294:4808346648081711:48081848ENSG00000160310.12ENST00000355680.3,ENST00000397638.2,ENST00000397637.1
exon_skip_3612532148081711:48081848:48083294:48083466:48084206:4808485748083294:48083466ENSG00000160310.12ENST00000355680.3,ENST00000397638.2,ENST00000397637.1,ENST00000440086.1,ENST00000486520.1

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for PRMT2

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003556804807865648078832Frame-shift
ENST000003976374807865648078832Frame-shift
ENST000003976384807865648078832Frame-shift
ENST000003556804808171148081848Frame-shift
ENST000003976374808171148081848Frame-shift
ENST000003976384808171148081848Frame-shift
ENST000003556804808329448083466Frame-shift
ENST000003976374808329448083466Frame-shift
ENST000003976384808329448083466Frame-shift
ENST000003556804806948648069651In-frame
ENST000003976374806948648069651In-frame
ENST000003976384806948648069651In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003556804807865648078832Frame-shift
ENST000003976374807865648078832Frame-shift
ENST000003976384807865648078832Frame-shift
ENST000003556804808171148081848Frame-shift
ENST000003976374808171148081848Frame-shift
ENST000003976384808171148081848Frame-shift
ENST000003556804808329448083466Frame-shift
ENST000003976374808329448083466Frame-shift
ENST000003976384808329448083466Frame-shift
ENST000003556804806948648069651In-frame
ENST000003976374806948648069651In-frame
ENST000003976384806948648069651In-frame

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Infer the effects of exon skipping event on protein functional features for PRMT2

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003556802705433480694864806965112521416163218
ENST000003976372897433480694864806965114441608163218
ENST0000039763821484334806948648069651695859163218

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003556802705433480694864806965112521416163218
ENST000003976372897433480694864806965114441608163218
ENST0000039763821484334806948648069651695859163218

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature


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SNVs in the skipped exons for PRMT2

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.
PRMT2_BRCA_exon_skip_361242_psi_boxplot.png
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PRMT2_COAD_exon_skip_361242_psi_boxplot.png
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PRMT2_LIHC_exon_skip_361242_psi_boxplot.png
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PRMT2_LUAD_exon_skip_361242_psi_boxplot.png
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PRMT2_STAD_exon_skip_361242_psi_boxplot.png
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check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A3A0-01exon_skip_361205
exon_skip_361204
exon_skip_361203
48069487480696514806963248069632Frame_Shift_DelG-p.W212fs
LIHCTCGA-DD-A3A0-01exon_skip_361218
exon_skip_361220
48078657480788324807871448078714Frame_Shift_DelG-p.G238fs
COADTCGA-AZ-6598-01exon_skip_361242
48080745480818484808076448080764Frame_Shift_DelT-p.E283fs
LIHCTCGA-DD-A1EG-01exon_skip_361242
48080745480818484808076448080764Frame_Shift_DelT-p.F285fs
STADTCGA-BR-8361-01exon_skip_361242
48080745480818484808076448080764Frame_Shift_DelT-p.E283fs
STADTCGA-BR-8361-01exon_skip_361242
48080745480818484808076448080764Frame_Shift_DelT-p.F284fs
STADTCGA-CG-5721-01exon_skip_361242
48080745480818484808076448080764Frame_Shift_DelT-p.E283fs
LIHCTCGA-DD-A39Y-01exon_skip_361253
exon_skip_361235
48083295480834664808342948083429Frame_Shift_DelG-p.W411fs
BRCATCGA-AN-A0XW-01exon_skip_361242
48080745480818484808077148080771Nonsense_MutationCGp.S286*
LUADTCGA-55-A4DF-01exon_skip_361242
48080745480818484808077148080771Nonsense_MutationCGp.S286*
STADTCGA-CG-5727-01exon_skip_361242
48080745480818484808179348081793Nonsense_MutationCTp.Q348*
STADTCGA-CG-5727-01exon_skip_361242
48080745480818484808179348081793Nonsense_MutationCTp.Q348X
STADTCGA-CG-5727-01exon_skip_361229
exon_skip_361247
48081712480818484808179348081793Nonsense_MutationCTp.Q348*
STADTCGA-CG-5727-01exon_skip_361229
exon_skip_361247
48081712480818484808179348081793Nonsense_MutationCTp.Q348X
SARCTCGA-DX-A3UC-01exon_skip_361253
exon_skip_361235
48083295480834664808335548083355Nonsense_MutationATp.R239*

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description
PRMT2_48078656_48078832_48080744_48081848_48083294_48083466_TCGA-AN-A0XW-01Sample: TCGA-AN-A0XW-01
Cancer type: BRCA
ESID: exon_skip_361242
Skipped exon start: 48080745
Skipped exon end: 48081848
Mutation start: 48080771
Mutation end: 48080771
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: G
AAchange: p.S286*
exon_skip_113989_BRCA_TCGA-AN-A0XW-01.png
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exon_skip_361242_BRCA_TCGA-AN-A0XW-01.png
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PRMT2_48078656_48078832_48080744_48081848_48083294_48083466_TCGA-55-A4DF-01Sample: TCGA-55-A4DF-01
Cancer type: LUAD
ESID: exon_skip_361242
Skipped exon start: 48080745
Skipped exon end: 48081848
Mutation start: 48080771
Mutation end: 48080771
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: G
AAchange: p.S286*
exon_skip_361242_LUAD_TCGA-55-A4DF-01.png
boxplot
PRMT2_48078656_48078832_48080744_48081848_48083294_48083466_TCGA-DD-A1EG-01Sample: TCGA-DD-A1EG-01
Cancer type: LIHC
ESID: exon_skip_361242
Skipped exon start: 48080745
Skipped exon end: 48081848
Mutation start: 48080764
Mutation end: 48080764
Mutation type: Frame_Shift_Del
Reference seq: T
Mutation seq: -
AAchange: p.F285fs
exon_skip_103075_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_100809_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_101656_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_10700_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_109033_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_110000_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_110381_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_110545_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_11218_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_11256_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_11259_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_11263_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_115462_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_115587_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_116330_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_121002_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_123667_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_12440_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_125045_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_129202_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_129996_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_130099_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_13071_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_131505_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_131697_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_133542_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_133548_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_134792_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_135418_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_135741_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_135763_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_135820_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_13608_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_138255_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_138373_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_138947_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_140996_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_141914_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_143841_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_143843_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_144075_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_144116_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_144125_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_146762_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_146776_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_146807_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_14772_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_148738_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_148740_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_14897_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_14899_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_15042_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_150985_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_153494_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_16928_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_17317_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_17318_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_17943_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_18708_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_19048_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_1906_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_19372_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_19902_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_20061_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_22876_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_2523_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_26461_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_27038_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_27065_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_283878_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_284109_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_288112_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_290222_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_290223_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_29032_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_290_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_291361_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_291973_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_29487_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_295443_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_297892_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_299242_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_30164_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_30165_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_302094_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_302095_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_302097_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_302181_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_305812_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_305815_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_3064_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_307291_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_30744_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_307494_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_307495_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_30789_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_30792_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_308209_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_308211_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_308911_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_309060_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_309486_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_309505_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_309539_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_311823_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_311841_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_312748_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_315763_LIHC_TCGA-DD-A1EG-01.png
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exon_skip_316803_LIHC_TCGA-DD-A1EG-01.png
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PRMT2_48078656_48078832_48080744_48081848_48083294_48083466_TCGA-BR-8361-01Sample: TCGA-BR-8361-01
Cancer type: STAD
ESID: exon_skip_361242
Skipped exon start: 48080745
Skipped exon end: 48081848
Mutation start: 48080764
Mutation end: 48080764
Mutation type: Frame_Shift_Del
Reference seq: T
Mutation seq: -
AAchange: p.E283fs
PRMT2_48078656_48078832_48080744_48081848_48083294_48083466_TCGA-BR-8361-01Sample: TCGA-BR-8361-01
Cancer type: STAD
ESID: exon_skip_361242
Skipped exon start: 48080745
Skipped exon end: 48081848
Mutation start: 48080764
Mutation end: 48080764
Mutation type: Frame_Shift_Del
Reference seq: T
Mutation seq: -
AAchange: p.F284fs
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PRMT2_48078656_48078832_48080744_48081848_48083294_48083466_TCGA-CG-5721-01Sample: TCGA-CG-5721-01
Cancer type: STAD
ESID: exon_skip_361242
Skipped exon start: 48080745
Skipped exon end: 48081848
Mutation start: 48080764
Mutation end: 48080764
Mutation type: Frame_Shift_Del
Reference seq: T
Mutation seq: -
AAchange: p.E283fs
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PRMT2_48069609_48069651_48083294_48083466_48084206_48084857_TCGA-DD-A39Y-01Sample: TCGA-DD-A39Y-01
Cancer type: LIHC
ESID: exon_skip_361235
Skipped exon start: 48083295
Skipped exon end: 48083466
Mutation start: 48083429
Mutation end: 48083429
Mutation type: Frame_Shift_Del
Reference seq: G
Mutation seq: -
AAchange: p.W411fs
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check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
SNU1040_LARGE_INTESTINE48080745480818484808076448080764Frame_Shift_DelT-p.F285fs
HUPT4_PANCREAS48080745480818484808086148080861Frame_Shift_DelT-p.I316fs
SW48_LARGE_INTESTINE48069487480696514806950648069506Missense_MutationGTp.S170I
HCC2450_LUNG48069487480696514806957948069579Missense_MutationGCp.Q194H
SNU1040_LARGE_INTESTINE48069487480696514806961648069616Missense_MutationGAp.V207M
AU565_BREAST48078657480788324807868848078688Missense_MutationCTp.A229V
SNU1040_LARGE_INTESTINE48078657480788324807869048078690Missense_MutationCTp.R230W
RH30_SOFT_TISSUE48078657480788324807875448078754Missense_MutationCAp.P251H
SJRH30_SOFT_TISSUE48078657480788324807875448078754Missense_MutationCAp.P251H
GP2D_LARGE_INTESTINE48080745480818484808085148080851Missense_MutationAGp.T313A
SNU1040_LARGE_INTESTINE48080745480818484808085448080854Missense_MutationGAp.V314M
RAJI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48081712480818484808173048081730Missense_MutationCTp.R327C
RAJI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48080745480818484808173048081730Missense_MutationCTp.R327C
NCIH1339_LUNG48081712480818484808176348081763Missense_MutationGAp.G338S
NCIH1339_LUNG48080745480818484808176348081763Missense_MutationGAp.G338S
CCRFCEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48081712480818484808178748081787Missense_MutationCTp.H346Y
CCRFCEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48080745480818484808178748081787Missense_MutationCTp.H346Y
PACADD137_PANCREAS48083295480834664808335948083359Missense_MutationGAp.V388M

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PRMT2

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENST00000486520.1KIRCrs116888171chr21:48081490T/C2.84e-03
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENST00000486520.1KIRCrs116888171chr21:48081490T/C3.29e-03
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENST00000486520.1PRADrs116888171chr21:48081490T/C2.67e-06
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENST00000486520.1PRADrs76674087chr21:48081215A/G1.12e-03
exon_skip_3612422148078656:48078832:48080744:48081848:48083294:4808346648080744:48081848ENST00000486520.1TGCTrs76674087chr21:48081215A/G6.59e-04

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PRMT2


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PRMT2


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RelatedDrugs for PRMT2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PRMT2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource