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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for CUL9 |
 Gene summary |
| Gene information | Gene symbol | CUL9 | Gene ID | 23113 |
| Gene name | cullin 9 | |
| Synonyms | H7AP1|PARC | |
| Cytomap | 6p21.1 | |
| Type of gene | protein-coding | |
| Description | cullin-9CUL-9UbcH7-associated protein 1p53-associated parkin-like cytoplasmic proteinparkin-like cytoplasmic p53 binding protein | |
| Modification date | 20180522 | |
| UniProtAcc | Q8IWT3 | |
| Context | PubMed: CUL9 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| CUL9 | GO:0016567 | protein ubiquitination | 24793696 |
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Exon skipping events across known transcript of Ensembl for CUL9 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for CUL9 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for CUL9 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_451973 | 6 | 43152039:43152643:43153193:43153348:43153692:43154193 | 43153193:43153348 | ENSG00000112659.9 | ENST00000354495.3,ENST00000451399.1,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_451975 | 6 | 43153692:43154193:43154697:43154833:43154983:43155177 | 43154697:43154833 | ENSG00000112659.9 | ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_451986 | 6 | 43154697:43154833:43154983:43155177:43155450:43155472 | 43154983:43155177 | ENSG00000112659.9 | ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_451996 | 6 | 43155646:43155856:43156260:43156453:43160738:43160946 | 43156260:43156453 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_451997 | 6 | 43164382:43164600:43166346:43166593:43167003:43167109 | 43166346:43166593 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_451999 | 6 | 43166427:43166593:43167003:43167109:43167666:43167894 | 43167003:43167109 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452000 | 6 | 43167666:43167894:43168173:43168264:43168400:43168572 | 43168173:43168264 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452002 | 6 | 43168400:43168572:43170453:43170559:43170846:43170942 | 43170453:43170559 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452004 | 6 | 43170846:43170942:43171154:43171330:43171591:43171725 | 43171154:43171330 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452009 | 6 | 43171591:43171725:43172097:43172277:43172485:43172595 | 43172097:43172277 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452012 | 6 | 43172097:43172277:43172485:43172595:43172670:43172853 | 43172485:43172595 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000512408.2,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452013 | 6 | 43172485:43172595:43172670:43172853:43173000:43173161 | 43172670:43172853 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452016 | 6 | 43172670:43172853:43173000:43173161:43173744:43173973 | 43173000:43173161 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452020 | 6 | 43173000:43173161:43173744:43173973:43174058:43174248 | 43173744:43173973 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452022 | 6 | 43173844:43173973:43174058:43174248:43180886:43181032 | 43174058:43174248 | ENSG00000112659.9 | ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452030 | 6 | 43188303:43188337:43188484:43188649:43188895:43189059 | 43188484:43188649 | ENSG00000112659.9 | ENST00000506830.1,ENST00000354495.3,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| exon_skip_452032 | 6 | 43191001:43191135:43191832:43191906:43191987:43192322 | 43191832:43191906 | ENSG00000112659.9 | ENST00000506830.1,ENST00000354495.3,ENST00000504647.1,ENST00000515773.1,ENST00000252050.4,ENST00000372647.2 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for CUL9 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_451973 | 6 | 43152039:43152643:43153193:43153348:43153692:43154193 | 43153193:43153348 | ENSG00000112659.9 | ENST00000252050.4,ENST00000451399.1,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_451975 | 6 | 43153692:43154193:43154697:43154833:43154983:43155177 | 43154697:43154833 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000372647.2 |
| exon_skip_451986 | 6 | 43154697:43154833:43154983:43155177:43155450:43155472 | 43154983:43155177 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000372647.2 |
| exon_skip_451996 | 6 | 43155646:43155856:43156260:43156453:43160738:43160946 | 43156260:43156453 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_451997 | 6 | 43164382:43164600:43166346:43166593:43167003:43167109 | 43166346:43166593 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_451999 | 6 | 43166427:43166593:43167003:43167109:43167666:43167894 | 43167003:43167109 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452000 | 6 | 43167666:43167894:43168173:43168264:43168400:43168572 | 43168173:43168264 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452002 | 6 | 43168400:43168572:43170453:43170559:43170846:43170942 | 43170453:43170559 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452004 | 6 | 43170846:43170942:43171154:43171330:43171591:43171725 | 43171154:43171330 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452009 | 6 | 43171591:43171725:43172097:43172277:43172485:43172595 | 43172097:43172277 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452012 | 6 | 43172097:43172277:43172485:43172595:43172670:43172853 | 43172485:43172595 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2,ENST00000512408.2 |
| exon_skip_452013 | 6 | 43172485:43172595:43172670:43172853:43173000:43173161 | 43172670:43172853 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452016 | 6 | 43172670:43172853:43173000:43173161:43173744:43173973 | 43173000:43173161 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452020 | 6 | 43173000:43173161:43173744:43173973:43174058:43174248 | 43173744:43173973 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452022 | 6 | 43173844:43173973:43174058:43174248:43180886:43181032 | 43174058:43174248 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2 |
| exon_skip_452030 | 6 | 43188303:43188337:43188484:43188649:43188895:43189059 | 43188484:43188649 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2,ENST00000506830.1 |
| exon_skip_452032 | 6 | 43191001:43191135:43191832:43191906:43191987:43192322 | 43191832:43191906 | ENSG00000112659.9 | ENST00000252050.4,ENST00000515773.1,ENST00000354495.3,ENST00000372647.2,ENST00000506830.1,ENST00000504647.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for CUL9 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000252050 | 43153193 | 43153348 | Frame-shift |
| ENST00000252050 | 43154697 | 43154833 | Frame-shift |
| ENST00000252050 | 43154983 | 43155177 | Frame-shift |
| ENST00000252050 | 43156260 | 43156453 | Frame-shift |
| ENST00000252050 | 43166346 | 43166593 | Frame-shift |
| ENST00000252050 | 43167003 | 43167109 | Frame-shift |
| ENST00000252050 | 43168173 | 43168264 | Frame-shift |
| ENST00000252050 | 43170453 | 43170559 | Frame-shift |
| ENST00000252050 | 43171154 | 43171330 | Frame-shift |
| ENST00000252050 | 43172485 | 43172595 | Frame-shift |
| ENST00000252050 | 43173000 | 43173161 | Frame-shift |
| ENST00000252050 | 43173744 | 43173973 | Frame-shift |
| ENST00000252050 | 43174058 | 43174248 | Frame-shift |
| ENST00000252050 | 43191832 | 43191906 | Frame-shift |
| ENST00000252050 | 43172097 | 43172277 | In-frame |
| ENST00000252050 | 43172670 | 43172853 | In-frame |
| ENST00000252050 | 43188484 | 43188649 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000252050 | 43153193 | 43153348 | Frame-shift |
| ENST00000252050 | 43154697 | 43154833 | Frame-shift |
| ENST00000252050 | 43154983 | 43155177 | Frame-shift |
| ENST00000252050 | 43156260 | 43156453 | Frame-shift |
| ENST00000252050 | 43166346 | 43166593 | Frame-shift |
| ENST00000252050 | 43167003 | 43167109 | Frame-shift |
| ENST00000252050 | 43168173 | 43168264 | Frame-shift |
| ENST00000252050 | 43170453 | 43170559 | Frame-shift |
| ENST00000252050 | 43171154 | 43171330 | Frame-shift |
| ENST00000252050 | 43172485 | 43172595 | Frame-shift |
| ENST00000252050 | 43173000 | 43173161 | Frame-shift |
| ENST00000252050 | 43173744 | 43173973 | Frame-shift |
| ENST00000252050 | 43174058 | 43174248 | Frame-shift |
| ENST00000252050 | 43191832 | 43191906 | Frame-shift |
| ENST00000252050 | 43172097 | 43172277 | In-frame |
| ENST00000252050 | 43172670 | 43172853 | In-frame |
| ENST00000252050 | 43188484 | 43188649 | In-frame |
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Infer the effects of exon skipping event on protein functional features for CUL9 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000252050 | 7797 | 2517 | 43172097 | 43172277 | 4244 | 4423 | 1386 | 1446 |
| ENST00000252050 | 7797 | 2517 | 43172670 | 43172853 | 4534 | 4716 | 1483 | 1544 |
| ENST00000252050 | 7797 | 2517 | 43188484 | 43188649 | 6508 | 6672 | 2141 | 2196 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000252050 | 7797 | 2517 | 43172097 | 43172277 | 4244 | 4423 | 1386 | 1446 |
| ENST00000252050 | 7797 | 2517 | 43172670 | 43172853 | 4534 | 4716 | 1483 | 1544 |
| ENST00000252050 | 7797 | 2517 | 43188484 | 43188649 | 6508 | 6672 | 2141 | 2196 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q8IWT3 | 1386 | 1446 | 1 | 2517 | Chain | ID=PRO_0000119815;Note=Cullin-9 |
| Q8IWT3 | 1483 | 1544 | 1 | 2517 | Chain | ID=PRO_0000119815;Note=Cullin-9 |
| Q8IWT3 | 2141 | 2196 | 1 | 2517 | Chain | ID=PRO_0000119815;Note=Cullin-9 |
| Q8IWT3 | 2141 | 2196 | 2180 | 2180 | Natural variant | ID=VAR_048845;Note=T->I;Dbxref=dbSNP:rs11962520 |
| Q8IWT3 | 2141 | 2196 | 2140 | 2203 | Zinc finger | Note=IBR-type |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q8IWT3 | 1386 | 1446 | 1 | 2517 | Chain | ID=PRO_0000119815;Note=Cullin-9 |
| Q8IWT3 | 1483 | 1544 | 1 | 2517 | Chain | ID=PRO_0000119815;Note=Cullin-9 |
| Q8IWT3 | 2141 | 2196 | 1 | 2517 | Chain | ID=PRO_0000119815;Note=Cullin-9 |
| Q8IWT3 | 2141 | 2196 | 2180 | 2180 | Natural variant | ID=VAR_048845;Note=T->I;Dbxref=dbSNP:rs11962520 |
| Q8IWT3 | 2141 | 2196 | 2140 | 2203 | Zinc finger | Note=IBR-type |
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SNVs in the skipped exons for CUL9 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_451973 | 43153194 | 43153348 | 43153255 | 43153255 | Frame_Shift_Del | T | - | p.D219fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_451975 | 43154698 | 43154833 | 43154805 | 43154805 | Frame_Shift_Del | G | - | p.K453fs |
| UCS | TCGA-N5-A4RJ-01 | exon_skip_451986 | 43154984 | 43155177 | 43155158 | 43155159 | Frame_Shift_Del | TT | - | p.521_521del |
| UCS | TCGA-N5-A4RJ-01 | exon_skip_451986 | 43154984 | 43155177 | 43155158 | 43155159 | Frame_Shift_Del | TT | - | p.L521fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_451999 | 43167004 | 43167109 | 43167064 | 43167064 | Frame_Shift_Del | G | - | p.L1037fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_452004 | 43171155 | 43171330 | 43171225 | 43171225 | Frame_Shift_Del | G | - | p.R1307fs |
| COAD | TCGA-A6-2676-01 | exon_skip_452009 | 43172098 | 43172277 | 43172149 | 43172150 | Frame_Shift_Del | AG | - | p.1404_1404del |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_452012 | 43172486 | 43172595 | 43172517 | 43172517 | Frame_Shift_Del | C | - | p.S1457fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_452013 | 43172671 | 43172853 | 43172710 | 43172710 | Frame_Shift_Del | T | - | p.F1497fs |
| COAD | TCGA-CM-6675-01 | exon_skip_452013 | 43172671 | 43172853 | 43172731 | 43172732 | Frame_Shift_Del | CT | - | p.1503_1504del |
| STAD | TCGA-CG-5734-01 | exon_skip_452032 | 43191833 | 43191906 | 43191861 | 43191861 | Frame_Shift_Del | C | - | p.S2438fs |
| STAD | TCGA-BR-4201-01 | exon_skip_452009 | 43172098 | 43172277 | 43172148 | 43172149 | Frame_Shift_Ins | - | AG | p.Q1404fs |
| STAD | TCGA-BR-4201-01 | exon_skip_452009 | 43172098 | 43172277 | 43172149 | 43172150 | Frame_Shift_Ins | - | AG | p.Q1404fs |
| SARC | TCGA-Z4-A9VC-01 | exon_skip_451975 | 43154698 | 43154833 | 43154707 | 43154707 | Nonsense_Mutation | C | T | p.Q421* |
| UCEC | TCGA-AX-A05Z-01 | exon_skip_451997 | 43166347 | 43166593 | 43166400 | 43166400 | Nonsense_Mutation | C | T | p.R953* |
| STAD | TCGA-BR-8680-01 | exon_skip_451997 | 43166347 | 43166593 | 43166427 | 43166427 | Nonsense_Mutation | G | T | p.E962* |
| STAD | TCGA-BR-8680-01 | exon_skip_451997 | 43166347 | 43166593 | 43166427 | 43166427 | Nonsense_Mutation | G | T | p.E962X |
| THCA | TCGA-DJ-A13L-01 | exon_skip_452016 | 43173001 | 43173161 | 43173160 | 43173160 | Nonsense_Mutation | C | T | p.Q1598X |
| UCEC | TCGA-A5-A0VO-01 | exon_skip_452020 | 43173745 | 43173973 | 43173902 | 43173902 | Nonsense_Mutation | C | T | p.Q1651* |
| LIHC | TCGA-WQ-A9G7-01 | exon_skip_452012 | 43172486 | 43172595 | 43172484 | 43172484 | Splice_Site | A | C | . |
| SKCM | TCGA-EE-A3JD-06 | exon_skip_452016 | 43173001 | 43173161 | 43173000 | 43173000 | Splice_Site | G | A | . |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| NCIH630_LARGE_INTESTINE | 43170454 | 43170559 | 43170518 | 43170518 | Frame_Shift_Del | G | - | p.G1239fs |
| LN18_CENTRAL_NERVOUS_SYSTEM | 43153194 | 43153348 | 43153241 | 43153241 | Missense_Mutation | G | A | p.E215K |
| SNU668_STOMACH | 43153194 | 43153348 | 43153259 | 43153259 | Missense_Mutation | G | A | p.D221N |
| NCIH1623_LUNG | 43153194 | 43153348 | 43153271 | 43153271 | Missense_Mutation | A | G | p.T225A |
| CW2_LARGE_INTESTINE | 43153194 | 43153348 | 43153314 | 43153314 | Missense_Mutation | A | G | p.H239R |
| HCC1438_LUNG | 43154698 | 43154833 | 43154720 | 43154720 | Missense_Mutation | G | A | p.R425H |
| HEC1A_ENDOMETRIUM | 43154698 | 43154833 | 43154761 | 43154761 | Missense_Mutation | C | A | p.P439T |
| KU1919_URINARY_TRACT | 43154984 | 43155177 | 43155032 | 43155032 | Missense_Mutation | C | T | p.P479L |
| SW1353_BONE | 43154984 | 43155177 | 43155066 | 43155066 | Missense_Mutation | A | C | p.R490S |
| SW1353_BONE | 43154984 | 43155177 | 43155067 | 43155067 | Missense_Mutation | G | C | p.V491L |
| AU565_BREAST | 43154984 | 43155177 | 43155133 | 43155133 | Missense_Mutation | G | C | p.E513Q |
| SKBR3_BREAST | 43154984 | 43155177 | 43155133 | 43155133 | Missense_Mutation | G | C | p.E513Q |
| YT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43154984 | 43155177 | 43155172 | 43155172 | Missense_Mutation | G | C | p.D526H |
| SNU175_LARGE_INTESTINE | 43156261 | 43156453 | 43156294 | 43156294 | Missense_Mutation | G | A | p.R674H |
| COLO699_LUNG | 43156261 | 43156453 | 43156320 | 43156320 | Missense_Mutation | G | T | p.A683S |
| BT474_BREAST | 43156261 | 43156453 | 43156381 | 43156381 | Missense_Mutation | C | G | p.S703C |
| KMOE2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43156261 | 43156453 | 43156417 | 43156417 | Missense_Mutation | G | T | p.R715L |
| MOLT13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43156261 | 43156453 | 43156431 | 43156431 | Missense_Mutation | G | A | p.V720I |
| RL952_ENDOMETRIUM | 43156261 | 43156453 | 43156435 | 43156435 | Missense_Mutation | G | A | p.R721H |
| HS739T_FIBROBLAST | 43156261 | 43156453 | 43156435 | 43156435 | Missense_Mutation | G | A | p.R721H |
| LMSU_STOMACH | 43156261 | 43156453 | 43156447 | 43156447 | Missense_Mutation | C | T | p.S725L |
| LS411N_LARGE_INTESTINE | 43166347 | 43166593 | 43166395 | 43166395 | Missense_Mutation | T | C | p.L951P |
| DU145_PROSTATE | 43166347 | 43166593 | 43166415 | 43166415 | Missense_Mutation | G | T | p.G958C |
| MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43166347 | 43166593 | 43166484 | 43166484 | Missense_Mutation | G | A | p.V981M |
| MFE319_ENDOMETRIUM | 43168174 | 43168264 | 43168202 | 43168202 | Missense_Mutation | G | T | p.R1138I |
| DND41_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43168174 | 43168264 | 43168205 | 43168205 | Missense_Mutation | G | A | p.R1139Q |
| CW2_LARGE_INTESTINE | 43170454 | 43170559 | 43170483 | 43170483 | Missense_Mutation | A | G | p.D1226G |
| SNU1040_LARGE_INTESTINE | 43171155 | 43171330 | 43171240 | 43171240 | Missense_Mutation | G | A | p.R1312H |
| SW1463_LARGE_INTESTINE | 43171155 | 43171330 | 43171267 | 43171267 | Missense_Mutation | G | A | p.R1321Q |
| BC3C_URINARY_TRACT | 43171155 | 43171330 | 43171325 | 43171325 | Missense_Mutation | T | G | p.C1340W |
| SNU475_LIVER | 43172098 | 43172277 | 43172113 | 43172113 | Missense_Mutation | G | A | p.S1392N |
| SKMEL2_SKIN | 43172098 | 43172277 | 43172275 | 43172275 | Missense_Mutation | C | G | p.P1446R |
| KARPAS231_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43172486 | 43172595 | 43172506 | 43172506 | Missense_Mutation | C | T | p.R1454W |
| EB3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43172486 | 43172595 | 43172507 | 43172507 | Missense_Mutation | G | A | p.R1454Q |
| HEC6_ENDOMETRIUM | 43172671 | 43172853 | 43172818 | 43172818 | Missense_Mutation | G | A | p.A1533T |
| IALM_LUNG | 43172671 | 43172853 | 43172818 | 43172818 | Missense_Mutation | G | A | p.A1533T |
| CP66MEL_SKIN | 43173745 | 43173973 | 43173780 | 43173780 | Missense_Mutation | C | T | p.S1610L |
| 253JBV_URINARY_TRACT | 43173745 | 43173973 | 43173832 | 43173832 | Missense_Mutation | C | G | p.N1627K |
| SUPHD1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43173745 | 43173973 | 43173917 | 43173917 | Missense_Mutation | G | A | p.D1656N |
| SNU1040_LARGE_INTESTINE | 43174059 | 43174248 | 43174123 | 43174123 | Missense_Mutation | C | A | p.S1696Y |
| SNU1040_LARGE_INTESTINE | 43174059 | 43174248 | 43174144 | 43174144 | Missense_Mutation | G | A | p.R1703H |
| SNU81_LARGE_INTESTINE | 43174059 | 43174248 | 43174208 | 43174208 | Missense_Mutation | C | A | p.F1724L |
| CMLT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43188485 | 43188649 | 43188503 | 43188503 | Missense_Mutation | C | T | p.R2148C |
| MOLT13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 43188485 | 43188649 | 43188543 | 43188543 | Missense_Mutation | C | T | p.T2161I |
| JHUEM1_ENDOMETRIUM | 43188485 | 43188649 | 43188564 | 43188564 | Missense_Mutation | G | A | p.R2168H |
| NCIH2172_LUNG | 43153194 | 43153348 | 43153241 | 43153241 | Nonsense_Mutation | G | T | p.E215* |
| MM383_SKIN | 43171155 | 43171330 | 43171317 | 43171317 | Nonsense_Mutation | C | T | p.Q1338* |
| LN464_CENTRAL_NERVOUS_SYSTEM | 43167004 | 43167109 | 43167004 | 43167004 | Splice_Site | G | T | p.R1017S |
| ACN_AUTONOMIC_GANGLIA | 43167004 | 43167109 | 43167004 | 43167004 | Splice_Site | G | T | p.R1017S |
| MDAMB157_BREAST | 43173001 | 43173161 | 43173160 | 43173160 | Splice_Site | C | A | p.Q1598K |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CUL9 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CUL9 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CUL9 |
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RelatedDrugs for CUL9 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CUL9 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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