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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for DCN |
 Gene summary |
| Gene information | Gene symbol | DCN | Gene ID | 1634 |
| Gene name | decorin | |
| Synonyms | CSCD|DSPG2|PG40|PGII|PGS2|SLRR1B | |
| Cytomap | 12q21.33 | |
| Type of gene | protein-coding | |
| Description | decorinbone proteoglycan IIdermatan sulphate proteoglycans IIproteoglycan core proteinsmall leucine-rich protein 1B | |
| Modification date | 20180522 | |
| UniProtAcc | P07585 | |
| Context | PubMed: DCN [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| DCN | GO:0010508 | positive regulation of autophagy | 23798385 |
| DCN | GO:0010596 | negative regulation of endothelial cell migration | 23798385 |
| DCN | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling | 23798385 |
| DCN | GO:0016239 | positive regulation of macroautophagy | 23798385 |
| DCN | GO:0016525 | negative regulation of angiogenesis | 23978385 |
| DCN | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway | 23798385 |
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Exon skipping events across known transcript of Ensembl for DCN from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for DCN |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for DCN |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_95240 | 12 | 91540012:91540029:91558381:91558494:91572118:91572178 | 91558381:91558494 | ENSG00000011465.12 | ENST00000303320.3,ENST00000441303.2 |
| exon_skip_95244 | 12 | 91546872:91546966:91550851:91550965:91552072:91552286 | 91550851:91550965 | ENSG00000011465.12 | ENST00000052754.5,ENST00000393155.1,ENST00000552962.1 |
| exon_skip_95246 | 12 | 91546872:91546966:91550851:91550965:91572118:91572178 | 91550851:91550965 | ENSG00000011465.12 | ENST00000420120.2,ENST00000228329.5 |
| exon_skip_95254 | 12 | 91550851:91550965:91552072:91552286:91558381:91558494 | 91552072:91552286 | ENSG00000011465.12 | ENST00000052754.5,ENST00000393155.1,ENST00000552962.1 |
| exon_skip_95259 | 12 | 91552252:91552286:91558381:91558494:91572118:91572329 | 91558381:91558494 | ENSG00000011465.12 | ENST00000549513.1,ENST00000052754.5,ENST00000393155.1,ENST00000550563.1,ENST00000552145.1,ENST00000552962.1,ENST00000547937.1 |
| exon_skip_95265 | 12 | 91572118:91572362:91573138:91573463:91576431:91576486 | 91573138:91573463 | ENSG00000011465.12 | ENST00000552962.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for DCN |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_95240 | 12 | 91540012:91540029:91558381:91558494:91572118:91572178 | 91558381:91558494 | ENSG00000011465.12 | ENST00000303320.3,ENST00000441303.2 |
| exon_skip_95244 | 12 | 91546872:91546966:91550851:91550965:91552072:91552286 | 91550851:91550965 | ENSG00000011465.12 | ENST00000052754.5,ENST00000393155.1,ENST00000552962.1 |
| exon_skip_95246 | 12 | 91546872:91546966:91550851:91550965:91572118:91572178 | 91550851:91550965 | ENSG00000011465.12 | ENST00000228329.5,ENST00000420120.2 |
| exon_skip_95254 | 12 | 91550851:91550965:91552072:91552286:91558381:91558494 | 91552072:91552286 | ENSG00000011465.12 | ENST00000052754.5,ENST00000393155.1,ENST00000552962.1 |
| exon_skip_95259 | 12 | 91552252:91552286:91558381:91558494:91572118:91572329 | 91558381:91558494 | ENSG00000011465.12 | ENST00000052754.5,ENST00000393155.1,ENST00000552962.1,ENST00000547937.1,ENST00000552145.1,ENST00000550563.1,ENST00000549513.1 |
| exon_skip_95265 | 12 | 91572118:91572362:91573138:91573463:91576431:91576486 | 91573138:91573463 | ENSG00000011465.12 | ENST00000552962.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for DCN |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000552962 | 91573138 | 91573463 | 3UTR-3UTR |
| ENST00000052754 | 91552072 | 91552286 | Frame-shift |
| ENST00000393155 | 91552072 | 91552286 | Frame-shift |
| ENST00000552962 | 91552072 | 91552286 | Frame-shift |
| ENST00000052754 | 91558381 | 91558494 | Frame-shift |
| ENST00000393155 | 91558381 | 91558494 | Frame-shift |
| ENST00000552962 | 91558381 | 91558494 | Frame-shift |
| ENST00000052754 | 91550851 | 91550965 | In-frame |
| ENST00000393155 | 91550851 | 91550965 | In-frame |
| ENST00000552962 | 91550851 | 91550965 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000552962 | 91573138 | 91573463 | 3UTR-3UTR |
| ENST00000052754 | 91552072 | 91552286 | Frame-shift |
| ENST00000393155 | 91552072 | 91552286 | Frame-shift |
| ENST00000552962 | 91552072 | 91552286 | Frame-shift |
| ENST00000052754 | 91558381 | 91558494 | Frame-shift |
| ENST00000393155 | 91558381 | 91558494 | Frame-shift |
| ENST00000552962 | 91558381 | 91558494 | Frame-shift |
| ENST00000052754 | 91550851 | 91550965 | In-frame |
| ENST00000393155 | 91550851 | 91550965 | In-frame |
| ENST00000552962 | 91550851 | 91550965 | In-frame |
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Infer the effects of exon skipping event on protein functional features for DCN |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000052754 | 2409 | 359 | 91550851 | 91550965 | 1041 | 1154 | 179 | 217 |
| ENST00000393155 | 2150 | 359 | 91550851 | 91550965 | 793 | 906 | 179 | 217 |
| ENST00000552962 | 1947 | 359 | 91550851 | 91550965 | 1067 | 1180 | 179 | 217 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000052754 | 2409 | 359 | 91550851 | 91550965 | 1041 | 1154 | 179 | 217 |
| ENST00000393155 | 2150 | 359 | 91550851 | 91550965 | 793 | 906 | 179 | 217 |
| ENST00000552962 | 1947 | 359 | 91550851 | 91550965 | 1067 | 1180 | 179 | 217 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| P07585 | 179 | 217 | 71 | 179 | Alternative sequence | ID=VSP_006172;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 71 | 179 | Alternative sequence | ID=VSP_006172;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 71 | 179 | Alternative sequence | ID=VSP_006172;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 73 | 219 | Alternative sequence | ID=VSP_006173;Note=In isoform C. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 73 | 219 | Alternative sequence | ID=VSP_006173;Note=In isoform C. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 73 | 219 | Alternative sequence | ID=VSP_006173;Note=In isoform C. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 76 | 359 | Alternative sequence | ID=VSP_006176;Note=In isoform E. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 76 | 359 | Alternative sequence | ID=VSP_006176;Note=In isoform E. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 76 | 359 | Alternative sequence | ID=VSP_006176;Note=In isoform E. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 109 | 295 | Alternative sequence | ID=VSP_006174;Note=In isoform D. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 109 | 295 | Alternative sequence | ID=VSP_006174;Note=In isoform D. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 109 | 295 | Alternative sequence | ID=VSP_006174;Note=In isoform D. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 31 | 359 | Chain | ID=PRO_0000032710;Note=Decorin |
| P07585 | 179 | 217 | 31 | 359 | Chain | ID=PRO_0000032710;Note=Decorin |
| P07585 | 179 | 217 | 31 | 359 | Chain | ID=PRO_0000032710;Note=Decorin |
| P07585 | 179 | 217 | 211 | 211 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P07585 | 179 | 217 | 211 | 211 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P07585 | 179 | 217 | 211 | 211 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P07585 | 179 | 217 | 163 | 186 | Repeat | Note=LRR 5 |
| P07585 | 179 | 217 | 163 | 186 | Repeat | Note=LRR 5 |
| P07585 | 179 | 217 | 163 | 186 | Repeat | Note=LRR 5 |
| P07585 | 179 | 217 | 187 | 212 | Repeat | Note=LRR 6 |
| P07585 | 179 | 217 | 187 | 212 | Repeat | Note=LRR 6 |
| P07585 | 179 | 217 | 187 | 212 | Repeat | Note=LRR 6 |
| P07585 | 179 | 217 | 213 | 233 | Repeat | Note=LRR 7 |
| P07585 | 179 | 217 | 213 | 233 | Repeat | Note=LRR 7 |
| P07585 | 179 | 217 | 213 | 233 | Repeat | Note=LRR 7 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| P07585 | 179 | 217 | 71 | 179 | Alternative sequence | ID=VSP_006172;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 71 | 179 | Alternative sequence | ID=VSP_006172;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 71 | 179 | Alternative sequence | ID=VSP_006172;Note=In isoform B. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 73 | 219 | Alternative sequence | ID=VSP_006173;Note=In isoform C. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 73 | 219 | Alternative sequence | ID=VSP_006173;Note=In isoform C. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 73 | 219 | Alternative sequence | ID=VSP_006173;Note=In isoform C. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 76 | 359 | Alternative sequence | ID=VSP_006176;Note=In isoform E. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 76 | 359 | Alternative sequence | ID=VSP_006176;Note=In isoform E. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 76 | 359 | Alternative sequence | ID=VSP_006176;Note=In isoform E. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 109 | 295 | Alternative sequence | ID=VSP_006174;Note=In isoform D. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 109 | 295 | Alternative sequence | ID=VSP_006174;Note=In isoform D. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 109 | 295 | Alternative sequence | ID=VSP_006174;Note=In isoform D. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4 |
| P07585 | 179 | 217 | 31 | 359 | Chain | ID=PRO_0000032710;Note=Decorin |
| P07585 | 179 | 217 | 31 | 359 | Chain | ID=PRO_0000032710;Note=Decorin |
| P07585 | 179 | 217 | 31 | 359 | Chain | ID=PRO_0000032710;Note=Decorin |
| P07585 | 179 | 217 | 211 | 211 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P07585 | 179 | 217 | 211 | 211 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P07585 | 179 | 217 | 211 | 211 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218 |
| P07585 | 179 | 217 | 163 | 186 | Repeat | Note=LRR 5 |
| P07585 | 179 | 217 | 163 | 186 | Repeat | Note=LRR 5 |
| P07585 | 179 | 217 | 163 | 186 | Repeat | Note=LRR 5 |
| P07585 | 179 | 217 | 187 | 212 | Repeat | Note=LRR 6 |
| P07585 | 179 | 217 | 187 | 212 | Repeat | Note=LRR 6 |
| P07585 | 179 | 217 | 187 | 212 | Repeat | Note=LRR 6 |
| P07585 | 179 | 217 | 213 | 233 | Repeat | Note=LRR 7 |
| P07585 | 179 | 217 | 213 | 233 | Repeat | Note=LRR 7 |
| P07585 | 179 | 217 | 213 | 233 | Repeat | Note=LRR 7 |
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SNVs in the skipped exons for DCN |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_95244 exon_skip_95246 | 91550852 | 91550965 | 91550926 | 91550926 | Frame_Shift_Del | T | - | p.N193fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_95254 | 91552073 | 91552286 | 91552231 | 91552231 | Frame_Shift_Del | G | - | p.P127fs |
| LIHC | TCGA-EP-A26S-01 | exon_skip_95240 exon_skip_95259 | 91558382 | 91558494 | 91558424 | 91558424 | Frame_Shift_Del | G | - | p.E95fs |
| LIHC | TCGA-EP-A26S-01 | exon_skip_95240 exon_skip_95259 | 91558382 | 91558494 | 91558424 | 91558424 | Frame_Shift_Del | G | - | p.T94fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_95240 exon_skip_95259 | 91558382 | 91558494 | 91558429 | 91558429 | Frame_Shift_Del | T | - | p.I93fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_95240 exon_skip_95259 | 91558382 | 91558494 | 91558429 | 91558429 | Frame_Shift_Del | T | - | p.I93fs |
| HNSC | TCGA-CN-5367-01 | exon_skip_95240 exon_skip_95259 | 91558382 | 91558494 | 91558464 | 91558464 | Frame_Shift_Del | G | - | p.P81fs |
| SKCM | TCGA-EE-A29E-06 | exon_skip_95254 | 91552073 | 91552286 | 91552088 | 91552088 | Nonsense_Mutation | G | A | p.Q175* |
| SKCM | TCGA-EE-A29E-06 | exon_skip_95254 | 91552073 | 91552286 | 91552088 | 91552088 | Nonsense_Mutation | G | A | p.Q175X |
| GBM | TCGA-06-0213-01 | exon_skip_95254 | 91552073 | 91552286 | 91552214 | 91552214 | Nonsense_Mutation | G | A | p.R133* |
| LIHC | TCGA-DD-AAD0-01 | exon_skip_95254 | 91552073 | 91552286 | 91552214 | 91552214 | Nonsense_Mutation | G | A | p.R133X |
| UCEC | TCGA-BS-A0UF-01 | exon_skip_95240 exon_skip_95259 | 91558382 | 91558494 | 91558441 | 91558441 | Nonsense_Mutation | G | A | p.Q89* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-BS-A0UF-01 |
| Cancer type: UCEC | |
| ESID: exon_skip_95259 | |
| Skipped exon start: 91558382 | |
| Skipped exon end: 91558494 | |
| Mutation start: 91558441 | |
| Mutation end: 91558441 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q89* | |
exon_skip_104037_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_105868_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_105985_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_115426_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_14705_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_147467_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_19372_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_286379_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_294437_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_321837_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_324767_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_345944_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_345950_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_382354_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_389258_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_389265_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_39691_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_40297_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_461887_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_482464_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_59390_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_82288_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_84605_UCEC_TCGA-BS-A0UF-01.png | |
exon_skip_95240_UCEC_TCGA-BS-A0UF-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| HEC108_ENDOMETRIUM | 91552073 | 91552286 | 91552160 | 91552160 | Frame_Shift_Del | T | - | p.T151fs |
| RKO_LARGE_INTESTINE | 91552073 | 91552286 | 91552168 | 91552169 | Frame_Shift_Ins | - | T | p.M148fs |
| TGBC11TKB_STOMACH | 91552073 | 91552286 | 91552168 | 91552169 | Frame_Shift_Ins | - | T | p.M148fs |
| TUHR4TKB_KIDNEY | 91550852 | 91550965 | 91550877 | 91550877 | Missense_Mutation | A | C | p.D209E |
| KASUMI2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 91550852 | 91550965 | 91550887 | 91550887 | Missense_Mutation | C | T | p.R206H |
| GP2D_LARGE_INTESTINE | 91552073 | 91552286 | 91552081 | 91552081 | Missense_Mutation | A | G | p.I177T |
| GP5D_LARGE_INTESTINE | 91552073 | 91552286 | 91552081 | 91552081 | Missense_Mutation | A | G | p.I177T |
| SUM149PT_BREAST | 91552073 | 91552286 | 91552123 | 91552123 | Missense_Mutation | G | A | p.T163I |
| NCIH1838_LUNG | 91552073 | 91552286 | 91552227 | 91552227 | Missense_Mutation | C | A | p.L128F |
| KARPAS384_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 91552073 | 91552286 | 91552231 | 91552231 | Missense_Mutation | G | A | p.P127L |
| HCC2998_LARGE_INTESTINE | 91558382 | 91558494 | 91558423 | 91558423 | Missense_Mutation | C | T | p.E95K |
| NCIH2286_LUNG | 91558382 | 91558494 | 91558447 | 91558447 | Missense_Mutation | C | G | p.D87H |
| HEC108_ENDOMETRIUM | 91558382 | 91558494 | 91558480 | 91558480 | Missense_Mutation | G | A | p.P76S |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for DCN |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for DCN |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for DCN |
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RelatedDrugs for DCN |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| P07585 | DB03754 | Tromethamine | Decorin | small molecule | approved |
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RelatedDiseases for DCN |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| DCN | C0014170 | Endometrial Neoplasms | 1 | CTD_human |
| DCN | C0016059 | Fibrosis | 1 | CTD_human |
| DCN | C0027707 | Nephritis, Interstitial | 1 | CTD_human |
| DCN | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| DCN | C0238288 | Muscular Dystrophy, Facioscapulohumeral | 1 | CTD_human |
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