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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for CANT1

check button Gene summary
Gene informationGene symbol

CANT1

Gene ID

124583

Gene namecalcium activated nucleotidase 1
SynonymsDBQD|DBQD1|EDM7|SCAN-1|SCAN1|SHAPY
Cytomap

17q25.3

Type of geneprotein-coding
Descriptionsoluble calcium-activated nucleotidase 1Ca2+-dependent endoplasmic reticulum nucleoside diphosphataseapyrase homologmicromelic dwarfism with vertebral and metaphyseal abnormalities and advanced carpotarsal ossificationputative MAPK-activating protein
Modification date20180523
UniProtAcc

Q8WVQ1

ContextPubMed: CANT1 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Exon skipping events across known transcript of Ensembl for CANT1 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for CANT1

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for CANT1

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_2941051776989865:76990002:76991099:76991303:76993073:7699372676991099:76991303ENSG00000171302.12ENST00000591773.1,ENST00000302345.2,ENST00000392446.5
exon_skip_2941061776993187:76993411:76993572:76993726:76993921:7699404576993572:76993726ENSG00000171302.12ENST00000588611.1
exon_skip_2941071776993588:76993726:76993921:76994045:77001453:7700156376993921:76994045ENSG00000171302.12ENST00000592033.1
exon_skip_2941081776993588:76993726:76993921:76994045:77005745:7700581276993921:76994045ENSG00000171302.12ENST00000591811.1
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENSG00000171302.12ENST00000586916.2
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENSG00000171302.12ENST00000591773.1
exon_skip_2941321776993921:76994045:76996181:76996352:77001453:7700156376996181:76996352ENSG00000171302.12ENST00000588611.1
exon_skip_2941381776993921:76994045:76996181:76996352:77005745:7700581276996181:76996352ENSG00000171302.12ENST00000588075.1,ENST00000590370.1
exon_skip_2941441776993921:76994045:77001453:77001563:77005745:7700581277001453:77001563ENSG00000171302.12ENST00000592033.1,ENST00000591625.1
exon_skip_2941511776994310:76994368:76996181:76996352:77001453:7700156376996181:76996352ENSG00000171302.12ENST00000587242.1,ENST00000591732.1
exon_skip_2941541776994310:76994368:76996181:76996352:77005745:7700581276996181:76996352ENSG00000171302.12ENST00000586916.2
exon_skip_2941651776996181:76996352:77001453:77001563:77004144:7700425377001453:77001563ENSG00000171302.12ENST00000591732.1
exon_skip_2941661776996181:76996352:77001453:77001563:77005745:7700581277001453:77001563ENSG00000171302.12ENST00000587242.1,ENST00000588611.1
exon_skip_2941691777001453:77001563:77004144:77004253:77005745:7700581277004144:77004253ENSG00000171302.12ENST00000591732.1

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for CANT1

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_2941051776989865:76990002:76991099:76991303:76993073:7699372676991099:76991303ENSG00000171302.12ENST00000392446.5,ENST00000302345.2,ENST00000591773.1
exon_skip_2941061776993187:76993411:76993572:76993726:76993921:7699404576993572:76993726ENSG00000171302.12ENST00000588611.1
exon_skip_2941071776993588:76993726:76993921:76994045:77001453:7700156376993921:76994045ENSG00000171302.12ENST00000592033.1
exon_skip_2941081776993588:76993726:76993921:76994045:77005745:7700581276993921:76994045ENSG00000171302.12ENST00000591811.1
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENSG00000171302.12ENST00000586916.2
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENSG00000171302.12ENST00000591773.1
exon_skip_2941321776993921:76994045:76996181:76996352:77001453:7700156376996181:76996352ENSG00000171302.12ENST00000588611.1
exon_skip_2941381776993921:76994045:76996181:76996352:77005745:7700581276996181:76996352ENSG00000171302.12ENST00000588075.1,ENST00000590370.1
exon_skip_2941441776993921:76994045:77001453:77001563:77005745:7700581277001453:77001563ENSG00000171302.12ENST00000592033.1,ENST00000591625.1
exon_skip_2941511776994310:76994368:76996181:76996352:77001453:7700156376996181:76996352ENSG00000171302.12ENST00000587242.1,ENST00000591732.1
exon_skip_2941541776994310:76994368:76996181:76996352:77005745:7700581276996181:76996352ENSG00000171302.12ENST00000586916.2
exon_skip_2941651776996181:76996352:77001453:77001563:77004144:7700425377001453:77001563ENSG00000171302.12ENST00000591732.1
exon_skip_2941661776996181:76996352:77001453:77001563:77005745:7700581277001453:77001563ENSG00000171302.12ENST00000588611.1,ENST00000587242.1
exon_skip_2941691777001453:77001563:77004144:77004253:77005745:7700581277004144:77004253ENSG00000171302.12ENST00000591732.1

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for CANT1

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000059177376994229769943683UTR-3UTR
ENST000003023457699109976991303In-frame
ENST000003924467699109976991303In-frame
ENST000005917737699109976991303In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000059177376994229769943683UTR-3UTR
ENST000003023457699109976991303In-frame
ENST000003924467699109976991303In-frame
ENST000005917737699109976991303In-frame

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Infer the effects of exon skipping event on protein functional features for CANT1

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003023453551401769910997699130311271330210278
ENST00000392446326940176991099769913038451048210278
ENST000005917731686401769910997699130310321235210278

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003023453551401769910997699130311271330210278
ENST00000392446326940176991099769913038451048210278
ENST000005917731686401769910997699130310321235210278

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q8WVQ1210278220245Alternative sequenceID=VSP_013760;Note=In isoform 2. KDERLYVGGLGKEWTTTTGDVVNENP->REIVRKRWRLVKQVSHVGVLGQWIQR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278220245Alternative sequenceID=VSP_013760;Note=In isoform 2. KDERLYVGGLGKEWTTTTGDVVNENP->REIVRKRWRLVKQVSHVGVLGQWIQR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278220245Alternative sequenceID=VSP_013760;Note=In isoform 2. KDERLYVGGLGKEWTTTTGDVVNENP->REIVRKRWRLVKQVSHVGVLGQWIQR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278246401Alternative sequenceID=VSP_013761;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278246401Alternative sequenceID=VSP_013761;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278246401Alternative sequenceID=VSP_013761;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278208211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278208211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278208211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278216220Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278216220Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278216220Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278223227Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278223227Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278223227Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278240242Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278240242Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278240242Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278247251Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278247251Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278247251Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278257261Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278257261Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278257261Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ12102781401ChainID=PRO_0000209925;Note=Soluble calcium-activated nucleotidase 1
Q8WVQ12102781401ChainID=PRO_0000209925;Note=Soluble calcium-activated nucleotidase 1
Q8WVQ12102781401ChainID=PRO_0000209925;Note=Soluble calcium-activated nucleotidase 1
Q8WVQ1210278244246HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278244246HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278244246HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278263272HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278263272HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278263272HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278215215Metal bindingNote=Calcium%3B via carbonyl oxygen;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244|PDB:1S18,ECO:0000244|PDB:1S1D,ECO:0000244|PDB:2H2N,ECO:0000244|PDB:2H2U,ECO:0000269|PubMed:15006348,ECO:0000269|
Q8WVQ1210278215215Metal bindingNote=Calcium%3B via carbonyl oxygen;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244|PDB:1S18,ECO:0000244|PDB:1S1D,ECO:0000244|PDB:2H2N,ECO:0000244|PDB:2H2U,ECO:0000269|PubMed:15006348,ECO:0000269|
Q8WVQ1210278215215Metal bindingNote=Calcium%3B via carbonyl oxygen;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244|PDB:1S18,ECO:0000244|PDB:1S1D,ECO:0000244|PDB:2H2N,ECO:0000244|PDB:2H2U,ECO:0000269|PubMed:15006348,ECO:0000269|
Q8WVQ1210278215215MutagenesisNote=Reduces activity by 99%25. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278215215MutagenesisNote=Reduces activity by 99%25. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278215215MutagenesisNote=Reduces activity by 99%25. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278246246MutagenesisNote=Increases activity 5-fold. E->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278246246MutagenesisNote=Increases activity 5-fold. E->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278246246MutagenesisNote=Increases activity 5-fold. E->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278256256MutagenesisNote=No effect on GDPase and ADPase activities. No effect on dimer formation%3B when associated with S-287. S->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256MutagenesisNote=No effect on GDPase and ADPase activities. No effect on dimer formation%3B when associated with S-287. S->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256MutagenesisNote=No effect on GDPase and ADPase activities. No effect on dimer formation%3B when associated with S-287. S->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278224224Natural variantID=VAR_068658;Note=In DBQD1%3B affects protein stability and secretion. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21037275;Dbxref=dbSNP:rs150181226,PMID:21037275
Q8WVQ1210278224224Natural variantID=VAR_068658;Note=In DBQD1%3B affects protein stability and secretion. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21037275;Dbxref=dbSNP:rs150181226,PMID:21037275
Q8WVQ1210278224224Natural variantID=VAR_068658;Note=In DBQD1%3B affects protein stability and secretion. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21037275;Dbxref=dbSNP:rs150181226,PMID:21037275
Q8WVQ1210278226226Natural variantID=VAR_068659;Note=In DBQD1 and EDM7%3B severely affects activity. V->M;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21037275,ECO:0000269|PubMed:21412251,ECO:0000269|PubMed:28742282;Dbxref=dbSNP:rs377546036,PMID:21037275,P
Q8WVQ1210278226226Natural variantID=VAR_068659;Note=In DBQD1 and EDM7%3B severely affects activity. V->M;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21037275,ECO:0000269|PubMed:21412251,ECO:0000269|PubMed:28742282;Dbxref=dbSNP:rs377546036,PMID:21037275,P
Q8WVQ1210278226226Natural variantID=VAR_068659;Note=In DBQD1 and EDM7%3B severely affects activity. V->M;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21037275,ECO:0000269|PubMed:21412251,ECO:0000269|PubMed:28742282;Dbxref=dbSNP:rs377546036,PMID:21037275,P
Q8WVQ1210278256256SiteNote=Important for dimer formation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256SiteNote=Important for dimer formation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256SiteNote=Important for dimer formation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ121027863401Topological domainNote=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q8WVQ121027863401Topological domainNote=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q8WVQ121027863401Topological domainNote=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q8WVQ1210278220245Alternative sequenceID=VSP_013760;Note=In isoform 2. KDERLYVGGLGKEWTTTTGDVVNENP->REIVRKRWRLVKQVSHVGVLGQWIQR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278220245Alternative sequenceID=VSP_013760;Note=In isoform 2. KDERLYVGGLGKEWTTTTGDVVNENP->REIVRKRWRLVKQVSHVGVLGQWIQR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278220245Alternative sequenceID=VSP_013760;Note=In isoform 2. KDERLYVGGLGKEWTTTTGDVVNENP->REIVRKRWRLVKQVSHVGVLGQWIQR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278246401Alternative sequenceID=VSP_013761;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278246401Alternative sequenceID=VSP_013761;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278246401Alternative sequenceID=VSP_013761;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12761501;Dbxref=PMID:12761501
Q8WVQ1210278208211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278208211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278208211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278216220Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278216220Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278216220Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278223227Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278223227Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278223227Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278240242Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278240242Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278240242Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278247251Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278247251Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278247251Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278257261Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278257261Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278257261Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ12102781401ChainID=PRO_0000209925;Note=Soluble calcium-activated nucleotidase 1
Q8WVQ12102781401ChainID=PRO_0000209925;Note=Soluble calcium-activated nucleotidase 1
Q8WVQ12102781401ChainID=PRO_0000209925;Note=Soluble calcium-activated nucleotidase 1
Q8WVQ1210278244246HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278244246HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278244246HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278263272HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278263272HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278263272HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1S1D
Q8WVQ1210278215215Metal bindingNote=Calcium%3B via carbonyl oxygen;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244|PDB:1S18,ECO:0000244|PDB:1S1D,ECO:0000244|PDB:2H2N,ECO:0000244|PDB:2H2U,ECO:0000269|PubMed:15006348,ECO:0000269|
Q8WVQ1210278215215Metal bindingNote=Calcium%3B via carbonyl oxygen;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244|PDB:1S18,ECO:0000244|PDB:1S1D,ECO:0000244|PDB:2H2N,ECO:0000244|PDB:2H2U,ECO:0000269|PubMed:15006348,ECO:0000269|
Q8WVQ1210278215215Metal bindingNote=Calcium%3B via carbonyl oxygen;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269,ECO:0000269;evidence=ECO:0000244|PDB:1S18,ECO:0000244|PDB:1S1D,ECO:0000244|PDB:2H2N,ECO:0000244|PDB:2H2U,ECO:0000269|PubMed:15006348,ECO:0000269|
Q8WVQ1210278215215MutagenesisNote=Reduces activity by 99%25. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278215215MutagenesisNote=Reduces activity by 99%25. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278215215MutagenesisNote=Reduces activity by 99%25. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278246246MutagenesisNote=Increases activity 5-fold. E->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278246246MutagenesisNote=Increases activity 5-fold. E->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278246246MutagenesisNote=Increases activity 5-fold. E->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15006348;Dbxref=PMID:15006348
Q8WVQ1210278256256MutagenesisNote=No effect on GDPase and ADPase activities. No effect on dimer formation%3B when associated with S-287. S->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256MutagenesisNote=No effect on GDPase and ADPase activities. No effect on dimer formation%3B when associated with S-287. S->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256MutagenesisNote=No effect on GDPase and ADPase activities. No effect on dimer formation%3B when associated with S-287. S->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278224224Natural variantID=VAR_068658;Note=In DBQD1%3B affects protein stability and secretion. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21037275;Dbxref=dbSNP:rs150181226,PMID:21037275
Q8WVQ1210278224224Natural variantID=VAR_068658;Note=In DBQD1%3B affects protein stability and secretion. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21037275;Dbxref=dbSNP:rs150181226,PMID:21037275
Q8WVQ1210278224224Natural variantID=VAR_068658;Note=In DBQD1%3B affects protein stability and secretion. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21037275;Dbxref=dbSNP:rs150181226,PMID:21037275
Q8WVQ1210278226226Natural variantID=VAR_068659;Note=In DBQD1 and EDM7%3B severely affects activity. V->M;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21037275,ECO:0000269|PubMed:21412251,ECO:0000269|PubMed:28742282;Dbxref=dbSNP:rs377546036,PMID:21037275,P
Q8WVQ1210278226226Natural variantID=VAR_068659;Note=In DBQD1 and EDM7%3B severely affects activity. V->M;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21037275,ECO:0000269|PubMed:21412251,ECO:0000269|PubMed:28742282;Dbxref=dbSNP:rs377546036,PMID:21037275,P
Q8WVQ1210278226226Natural variantID=VAR_068659;Note=In DBQD1 and EDM7%3B severely affects activity. V->M;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21037275,ECO:0000269|PubMed:21412251,ECO:0000269|PubMed:28742282;Dbxref=dbSNP:rs377546036,PMID:21037275,P
Q8WVQ1210278256256SiteNote=Important for dimer formation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256SiteNote=Important for dimer formation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ1210278256256SiteNote=Important for dimer formation;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16835225;Dbxref=PMID:16835225
Q8WVQ121027863401Topological domainNote=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q8WVQ121027863401Topological domainNote=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q8WVQ121027863401Topological domainNote=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255


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SNVs in the skipped exons for CANT1

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
KIRCTCGA-B8-5553-0176991100769913037699124176991241Nonsense_MutationCAp.E232X
PAADTCGA-S4-A8RP-0176991100769913037699127176991271Nonsense_MutationCAp.E222X

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
SISO_CERVIX76993573769937267699358176993581Frame_Shift_DelG-p.R42fs
GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE76993573769937267699358176993581Frame_Shift_DelG-p.R42fs
SNU175_LARGE_INTESTINE76993573769937267699363376993634Frame_Shift_Ins-Cp.G24fs
NCIH2066_LUNG76991100769913037699112676991126Missense_MutationCAp.R270L
LS411N_LARGE_INTESTINE76991100769913037699116876991168Missense_MutationCTp.S256N
LC1F_LUNG76993573769937267699359376993593Missense_MutationGAp.R38C
LC1SQ_LUNG76993573769937267699359376993593Missense_MutationGAp.R38C
SKMEL24_SKIN76993573769937267699363776993637Missense_MutationCTp.G23E
SKMEL24_SKIN76993573769937267699363876993638Missense_MutationCTp.G23R
SW48_LARGE_INTESTINE76993573769937267699364176993641Missense_MutationCTp.V22M
YD38_UPPER_AERODIGESTIVE_TRACT76993573769937267699367776993677Missense_MutationCTp.E10K
JVM3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE76991100769913037699129276991292Nonsense_MutationCAp.E215*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CANT1

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2GBMrs2377301chr17:76994369A/G4.74e-08
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2GBMrs2377301chr17:76994369A/G1.05e-03
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2CESCrs2377301chr17:76994369A/G3.71e-11
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2CESCrs2377301chr17:76994369A/G6.39e-10
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2COADrs2377301chr17:76994369A/G8.86e-25
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2COADrs2377301chr17:76994369A/G4.57e-17
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2COADrs2377301chr17:76994369A/G7.47e-07
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2BLCArs2377301chr17:76994369A/G5.14e-17
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2BLCArs2377301chr17:76994369A/G2.27e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2BLCArs2377301chr17:76994369A/G6.41e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2HNSCrs2377301chr17:76994369A/G1.18e-24
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2HNSCrs2377301chr17:76994369A/G3.01e-18
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2HNSCrs2377301chr17:76994369A/G6.72e-05
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2KIRPrs2377301chr17:76994369A/G1.09e-09
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2KIRPrs2377301chr17:76994369A/G2.37e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LGGrs2377301chr17:76994369A/G3.64e-15
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LGGrs2377301chr17:76994369A/G1.39e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LGGrs2377301chr17:76994369A/G3.88e-05
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2KIRCrs2377301chr17:76994369A/G1.62e-18
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2KIRCrs2377301chr17:76994369A/G2.91e-09
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2KIRCrs2377301chr17:76994369A/G2.13e-07
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LUADrs2377301chr17:76994369A/G3.39e-17
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LUADrs2377301chr17:76994369A/G4.35e-17
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LIHCrs2377301chr17:76994369A/G3.70e-10
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LUSCrs2377301chr17:76994369A/G4.93e-20
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LUSCrs2377301chr17:76994369A/G2.40e-18
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2LUSCrs2377301chr17:76994369A/G2.16e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2READrs2377301chr17:76994369A/G8.71e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2READrs2377301chr17:76994369A/G1.23e-04
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2PAADrs2377301chr17:76994369A/G1.03e-07
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2PAADrs2377301chr17:76994369A/G7.40e-05
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2PAADrs2377301chr17:76994369A/G1.04e-03
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2PRADrs2377301chr17:76994369A/G2.67e-32
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2PRADrs2377301chr17:76994369A/G7.74e-15
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2PRADrs2377301chr17:76994369A/G2.58e-12
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2SARCrs2377301chr17:76994369A/G3.52e-07
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2THYMrs2377301chr17:76994369A/G1.70e-04
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2TGCTrs2377301chr17:76994369A/G7.01e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2TGCTrs2377301chr17:76994369A/G1.90e-05
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2SKCMrs2377301chr17:76994369A/G4.90e-05
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2STADrs2377301chr17:76994369A/G5.96e-19
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2STADrs2377301chr17:76994369A/G5.48e-16
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2STADrs2377301chr17:76994369A/G9.51e-05
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2THCArs2377301chr17:76994369A/G2.25e-26
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2THCArs2377301chr17:76994369A/G8.84e-09
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2THCArs2377301chr17:76994369A/G2.64e-06
exon_skip_2941181776993921:76994045:76994229:76994368:76996181:7699633576994229:76994368ENST00000586916.2UCECrs2377301chr17:76994369A/G1.42e-09
exon_skip_2941511776994310:76994368:76996181:76996352:77001453:7700156376996181:76996352ENST00000587242.1,ENST00000591732.1READrs7214331chr17:76996189T/C2.60e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1GBMrs2377301chr17:76994369A/G4.74e-08
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1GBMrs2377301chr17:76994369A/G1.05e-03
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1CESCrs2377301chr17:76994369A/G3.71e-11
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1CESCrs2377301chr17:76994369A/G6.39e-10
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1COADrs2377301chr17:76994369A/G8.86e-25
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1COADrs2377301chr17:76994369A/G4.57e-17
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1COADrs2377301chr17:76994369A/G7.47e-07
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1BLCArs2377301chr17:76994369A/G5.14e-17
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1BLCArs2377301chr17:76994369A/G2.27e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1BLCArs2377301chr17:76994369A/G6.41e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1HNSCrs2377301chr17:76994369A/G1.18e-24
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1HNSCrs2377301chr17:76994369A/G3.01e-18
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1HNSCrs2377301chr17:76994369A/G6.72e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1KIRPrs2377301chr17:76994369A/G1.09e-09
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1KIRPrs2377301chr17:76994369A/G2.37e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LGGrs2377301chr17:76994369A/G3.64e-15
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LGGrs2377301chr17:76994369A/G1.39e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LGGrs2377301chr17:76994369A/G3.88e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1KIRCrs2377301chr17:76994369A/G1.62e-18
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1KIRCrs2377301chr17:76994369A/G2.91e-09
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1KIRCrs2377301chr17:76994369A/G2.13e-07
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LUADrs2377301chr17:76994369A/G3.39e-17
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LUADrs2377301chr17:76994369A/G4.35e-17
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LIHCrs2377301chr17:76994369A/G3.70e-10
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LUSCrs2377301chr17:76994369A/G4.93e-20
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LUSCrs2377301chr17:76994369A/G2.40e-18
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1LUSCrs2377301chr17:76994369A/G2.16e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1READrs2377301chr17:76994369A/G8.71e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1READrs2377301chr17:76994369A/G1.23e-04
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1PAADrs2377301chr17:76994369A/G1.03e-07
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1PAADrs2377301chr17:76994369A/G7.40e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1PAADrs2377301chr17:76994369A/G1.04e-03
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1PRADrs2377301chr17:76994369A/G2.67e-32
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1PRADrs2377301chr17:76994369A/G7.74e-15
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1PRADrs2377301chr17:76994369A/G2.58e-12
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1SARCrs2377301chr17:76994369A/G3.52e-07
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1THYMrs2377301chr17:76994369A/G1.70e-04
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1TGCTrs2377301chr17:76994369A/G7.01e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1TGCTrs2377301chr17:76994369A/G1.90e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1SKCMrs2377301chr17:76994369A/G4.90e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1STADrs2377301chr17:76994369A/G5.96e-19
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1STADrs2377301chr17:76994369A/G5.48e-16
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1STADrs2377301chr17:76994369A/G9.51e-05
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1THCArs2377301chr17:76994369A/G2.25e-26
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1THCArs2377301chr17:76994369A/G8.84e-09
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1THCArs2377301chr17:76994369A/G2.64e-06
exon_skip_2941221776993921:76994045:76994229:76994368:77005745:7700581276994229:76994368ENST00000591773.1UCECrs2377301chr17:76994369A/G1.42e-09
exon_skip_2941321776993921:76994045:76996181:76996352:77001453:7700156376996181:76996352ENST00000588611.1READrs7214331chr17:76996189T/C2.60e-05
exon_skip_2941541776994310:76994368:76996181:76996352:77005745:7700581276996181:76996352ENST00000586916.2READrs7214331chr17:76996189T/C2.60e-05
exon_skip_2941381776993921:76994045:76996181:76996352:77005745:7700581276996181:76996352ENST00000588075.1,ENST00000590370.1READrs7214331chr17:76996189T/C2.60e-05

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CANT1


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CANT1


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RelatedDrugs for CANT1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
Q8WVQ1DB03754TromethamineSoluble calcium-activated nucleotidase 1small moleculeapproved

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RelatedDiseases for CANT1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
CANT1C4012146DESBUQUOIS DYSPLASIA 14UNIPROT