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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for USP19 |
 Gene summary |
| Gene information | Gene symbol | USP19 | Gene ID | 10869 |
| Gene name | ubiquitin specific peptidase 19 | |
| Synonyms | ZMYND9 | |
| Cytomap | 3p21.31 | |
| Type of gene | protein-coding | |
| Description | ubiquitin carboxyl-terminal hydrolase 19deubiquitinating enzyme 19ubiquitin specific protease 19ubiquitin thioesterase 19ubiquitin thiolesterase 19ubiquitin-specific-processing protease 19zinc finger MYND domain-containing protein 9 | |
| Modification date | 20180523 | |
| UniProtAcc | O94966 | |
| Context | PubMed: USP19 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| USP19 | GO:0030433 | ubiquitin-dependent ERAD pathway | 19465887 |
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Exon skipping events across known transcript of Ensembl for USP19 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for USP19 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for USP19 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_384049 | 3 | 49149716:49149835:49149921:49150062:49151424:49151526 | 49149921:49150062 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| exon_skip_384052 | 3 | 49151424:49151526:49151606:49151717:49152195:49152306 | 49151606:49151717 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| exon_skip_384055 | 3 | 49152195:49152306:49152391:49152550:49152660:49152794 | 49152391:49152550 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| exon_skip_384056 | 3 | 49153156:49153371:49153479:49153595:49153712:49153784 | 49153479:49153595 | ENSG00000172046.14 | ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| exon_skip_384057 | 3 | 49153156:49153377:49153479:49153595:49153712:49153784 | 49153479:49153595 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000306026.5 |
| exon_skip_384059 | 3 | 49153480:49153595:49153712:49153784:49153883:49154040 | 49153712:49153784 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398896.1,ENST00000398898.2,ENST00000464931.1,ENST00000417901.1,ENST00000306026.5,ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| exon_skip_384062 | 3 | 49153723:49153784:49153883:49154040:49154159:49154376 | 49153883:49154040 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398896.1,ENST00000398898.2,ENST00000464931.1,ENST00000417901.1,ENST00000306026.5,ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| exon_skip_384067 | 3 | 49154166:49154376:49154491:49154791:49154869:49154992 | 49154491:49154791 | ENSG00000172046.14 | ENST00000398892.3,ENST00000398898.2 |
| exon_skip_384069 | 3 | 49154166:49154376:49154491:49154794:49154869:49154992 | 49154491:49154794 | ENSG00000172046.14 | ENST00000417901.1,ENST00000306026.5,ENST00000434032.2 |
| exon_skip_384070 | 3 | 49154166:49154376:49154491:49154794:49154899:49155003 | 49154491:49154794 | ENSG00000172046.14 | ENST00000453664.1 |
| exon_skip_384075 | 3 | 49154166:49154376:49154869:49155003:49155089:49155144 | 49154869:49155003 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398888.2 |
| exon_skip_384085 | 3 | 49155089:49155218:49155379:49155553:49156454:49156714 | 49155379:49155553 | ENSG00000172046.14 | ENST00000306026.5,ENST00000488993.1 |
| exon_skip_384089 | 3 | 49155089:49155263:49155379:49155553:49156454:49156714 | 49155379:49155553 | ENSG00000172046.14 | ENST00000417901.1,ENST00000491859.1,ENST00000453664.1,ENST00000434032.2,ENST00000398888.2 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for USP19 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_384049 | 3 | 49149716:49149835:49149921:49150062:49151424:49151526 | 49149921:49150062 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000398892.3,ENST00000398888.2,ENST00000434032.2 |
| exon_skip_384052 | 3 | 49151424:49151526:49151606:49151717:49152195:49152306 | 49151606:49151717 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000398892.3,ENST00000398888.2,ENST00000434032.2 |
| exon_skip_384055 | 3 | 49152195:49152306:49152391:49152550:49152660:49152794 | 49152391:49152550 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000398892.3,ENST00000398888.2,ENST00000434032.2 |
| exon_skip_384056 | 3 | 49153156:49153371:49153479:49153595:49153712:49153784 | 49153479:49153595 | ENSG00000172046.14 | ENST00000453664.1,ENST00000398888.2,ENST00000434032.2 |
| exon_skip_384057 | 3 | 49153156:49153377:49153479:49153595:49153712:49153784 | 49153479:49153595 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000398892.3,ENST00000306026.5 |
| exon_skip_384059 | 3 | 49153480:49153595:49153712:49153784:49153883:49154040 | 49153712:49153784 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000398892.3,ENST00000398888.2,ENST00000434032.2,ENST00000306026.5,ENST00000464931.1 |
| exon_skip_384062 | 3 | 49153723:49153784:49153883:49154040:49154159:49154376 | 49153883:49154040 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398898.2,ENST00000417901.1,ENST00000453664.1,ENST00000398892.3,ENST00000398888.2,ENST00000434032.2,ENST00000306026.5,ENST00000464931.1 |
| exon_skip_384067 | 3 | 49154166:49154376:49154491:49154791:49154869:49154992 | 49154491:49154791 | ENSG00000172046.14 | ENST00000398898.2,ENST00000398892.3 |
| exon_skip_384069 | 3 | 49154166:49154376:49154491:49154794:49154869:49154992 | 49154491:49154794 | ENSG00000172046.14 | ENST00000417901.1,ENST00000434032.2,ENST00000306026.5 |
| exon_skip_384070 | 3 | 49154166:49154376:49154491:49154794:49154899:49155003 | 49154491:49154794 | ENSG00000172046.14 | ENST00000453664.1 |
| exon_skip_384075 | 3 | 49154166:49154376:49154869:49155003:49155089:49155144 | 49154869:49155003 | ENSG00000172046.14 | ENST00000398896.1,ENST00000398888.2 |
| exon_skip_384089 | 3 | 49155089:49155263:49155379:49155553:49156454:49156714 | 49155379:49155553 | ENSG00000172046.14 | ENST00000417901.1,ENST00000453664.1,ENST00000398888.2,ENST00000434032.2,ENST00000491859.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for USP19 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000398888 | 49153479 | 49153595 | Frame-shift |
| ENST00000398888 | 49153883 | 49154040 | Frame-shift |
| ENST00000398888 | 49154869 | 49155003 | Frame-shift |
| ENST00000398888 | 49149921 | 49150062 | In-frame |
| ENST00000398888 | 49151606 | 49151717 | In-frame |
| ENST00000398888 | 49152391 | 49152550 | In-frame |
| ENST00000398888 | 49153712 | 49153784 | In-frame |
| ENST00000398888 | 49155379 | 49155553 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000398888 | 49153479 | 49153595 | Frame-shift |
| ENST00000398888 | 49153883 | 49154040 | Frame-shift |
| ENST00000398888 | 49154869 | 49155003 | Frame-shift |
| ENST00000398888 | 49149921 | 49150062 | In-frame |
| ENST00000398888 | 49151606 | 49151717 | In-frame |
| ENST00000398888 | 49152391 | 49152550 | In-frame |
| ENST00000398888 | 49153712 | 49153784 | In-frame |
| ENST00000398888 | 49155379 | 49155553 | In-frame |
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Infer the effects of exon skipping event on protein functional features for USP19 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000398888 | 4576 | 1318 | 49155379 | 49155553 | 444 | 617 | 41 | 99 |
| ENST00000398888 | 4576 | 1318 | 49153712 | 49153784 | 1300 | 1371 | 327 | 350 |
| ENST00000398888 | 4576 | 1318 | 49152391 | 49152550 | 2033 | 2191 | 571 | 624 |
| ENST00000398888 | 4576 | 1318 | 49151606 | 49151717 | 2303 | 2413 | 661 | 698 |
| ENST00000398888 | 4576 | 1318 | 49149921 | 49150062 | 2516 | 2656 | 732 | 779 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000398888 | 4576 | 1318 | 49155379 | 49155553 | 444 | 617 | 41 | 99 |
| ENST00000398888 | 4576 | 1318 | 49153712 | 49153784 | 1300 | 1371 | 327 | 350 |
| ENST00000398888 | 4576 | 1318 | 49152391 | 49152550 | 2033 | 2191 | 571 | 624 |
| ENST00000398888 | 4576 | 1318 | 49151606 | 49151717 | 2303 | 2413 | 661 | 698 |
| ENST00000398888 | 4576 | 1318 | 49149921 | 49150062 | 2516 | 2656 | 732 | 779 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for USP19 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_384049 | 49149922 | 49150062 | 49150045 | 49150045 | Frame_Shift_Del | A | - | p.F829fs |
| STAD | TCGA-BR-4363-01 | exon_skip_384056 exon_skip_384057 | 49153480 | 49153595 | 49153503 | 49153503 | Frame_Shift_Del | C | - | p.G382fs |
| STAD | TCGA-BR-4363-01 | exon_skip_384056 exon_skip_384057 | 49153480 | 49153595 | 49153503 | 49153503 | Frame_Shift_Del | C | - | p.G483fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_384056 exon_skip_384057 | 49153480 | 49153595 | 49153581 | 49153581 | Frame_Shift_Del | G | - | p.P447fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_384075 | 49154870 | 49155003 | 49154901 | 49154901 | Frame_Shift_Del | T | - | p.K192fs |
| STAD | TCGA-BR-4361-01 | exon_skip_384056 exon_skip_384057 | 49153480 | 49153595 | 49153503 | 49153504 | Frame_Shift_Ins | - | C | p.G382fs |
| COAD | TCGA-AZ-6598-01 | exon_skip_384067 | 49154492 | 49154791 | 49154737 | 49154737 | Nonsense_Mutation | G | A | p.Q212X |
| COAD | TCGA-AZ-6598-01 | exon_skip_384070 exon_skip_384069 | 49154492 | 49154794 | 49154737 | 49154737 | Nonsense_Mutation | G | A | p.Q212X |
| LUAD | TCGA-05-4420-01 | exon_skip_384052 | 49151607 | 49151717 | 49151718 | 49151718 | Splice_Site | C | A | p.V662_splice |
| CESC | TCGA-DG-A2KL-01 | exon_skip_384062 | 49153884 | 49154040 | 49154041 | 49154041 | Splice_Site | C | G | e6-1 |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-AZ-6598-01 |
| Cancer type: COAD | |
| ESID: exon_skip_384069 | |
| Skipped exon start: 49154492 | |
| Skipped exon end: 49154794 | |
| Mutation start: 49154737 | |
| Mutation end: 49154737 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q212X | |
| Sample: TCGA-AZ-6598-01 |
| Cancer type: COAD | |
| ESID: exon_skip_384067 | |
| Skipped exon start: 49154492 | |
| Skipped exon end: 49154791 | |
| Mutation start: 49154737 | |
| Mutation end: 49154737 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q212X | |
exon_skip_11218_COAD_TCGA-AZ-6598-01.png | |
exon_skip_11256_COAD_TCGA-AZ-6598-01.png | |
exon_skip_11259_COAD_TCGA-AZ-6598-01.png | |
exon_skip_11263_COAD_TCGA-AZ-6598-01.png | |
exon_skip_135111_COAD_TCGA-AZ-6598-01.png | |
exon_skip_135112_COAD_TCGA-AZ-6598-01.png | |
exon_skip_135114_COAD_TCGA-AZ-6598-01.png | |
exon_skip_139080_COAD_TCGA-AZ-6598-01.png | |
exon_skip_142268_COAD_TCGA-AZ-6598-01.png | |
exon_skip_149455_COAD_TCGA-AZ-6598-01.png | |
exon_skip_300996_COAD_TCGA-AZ-6598-01.png | |
exon_skip_303809_COAD_TCGA-AZ-6598-01.png | |
exon_skip_357723_COAD_TCGA-AZ-6598-01.png | |
exon_skip_384067_COAD_TCGA-AZ-6598-01.png | |
exon_skip_384069_COAD_TCGA-AZ-6598-01.png | |
exon_skip_384070_COAD_TCGA-AZ-6598-01.png | |
exon_skip_434039_COAD_TCGA-AZ-6598-01.png | |
exon_skip_434040_COAD_TCGA-AZ-6598-01.png | |
exon_skip_434375_COAD_TCGA-AZ-6598-01.png | |
exon_skip_434763_COAD_TCGA-AZ-6598-01.png | |
exon_skip_439048_COAD_TCGA-AZ-6598-01.png | |
exon_skip_49506_COAD_TCGA-AZ-6598-01.png | |
exon_skip_54471_COAD_TCGA-AZ-6598-01.png | |
exon_skip_54472_COAD_TCGA-AZ-6598-01.png | |
exon_skip_84515_COAD_TCGA-AZ-6598-01.png | |
 | Sample: TCGA-AZ-6598-01 |
| Cancer type: COAD | |
| ESID: exon_skip_384069 | |
| Skipped exon start: 49154492 | |
| Skipped exon end: 49154794 | |
| Mutation start: 49154737 | |
| Mutation end: 49154737 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q212X | |
| Sample: TCGA-AZ-6598-01 |
| Cancer type: COAD | |
| ESID: exon_skip_384067 | |
| Skipped exon start: 49154492 | |
| Skipped exon end: 49154791 | |
| Mutation start: 49154737 | |
| Mutation end: 49154737 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q212X | |
| exon_skip_11218_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_11256_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_11259_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_11263_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_135111_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_135112_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_135114_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_139080_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_142268_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_149455_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_300996_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_303809_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_357723_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_384067_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_384069_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_384070_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434039_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434040_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434375_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434763_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_439048_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_49506_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_54471_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_54472_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_84515_COAD_TCGA-AZ-6598-01.png | |
 | Sample: TCGA-AZ-6598-01 |
| Cancer type: COAD | |
| ESID: exon_skip_384069 | |
| Skipped exon start: 49154492 | |
| Skipped exon end: 49154794 | |
| Mutation start: 49154737 | |
| Mutation end: 49154737 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q212X | |
| Sample: TCGA-AZ-6598-01 |
| Cancer type: COAD | |
| ESID: exon_skip_384067 | |
| Skipped exon start: 49154492 | |
| Skipped exon end: 49154791 | |
| Mutation start: 49154737 | |
| Mutation end: 49154737 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: p.Q212X | |
| exon_skip_11218_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_11256_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_11259_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_11263_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_135111_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_135112_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_135114_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_139080_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_142268_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_149455_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_300996_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_303809_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_357723_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_384067_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_384069_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_384070_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434039_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434040_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434375_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_434763_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_439048_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_49506_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_54471_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_54472_COAD_TCGA-AZ-6598-01.png | |
| exon_skip_84515_COAD_TCGA-AZ-6598-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| PANC0213_PANCREAS | 49149922 | 49150062 | 49150050 | 49150050 | Missense_Mutation | G | C | p.R737G |
| DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 49151607 | 49151717 | 49151623 | 49151623 | Missense_Mutation | T | C | p.H693R |
| 42MGBA_CENTRAL_NERVOUS_SYSTEM | 49151607 | 49151717 | 49151702 | 49151702 | Missense_Mutation | C | A | p.D667Y |
| SW684_SOFT_TISSUE | 49152392 | 49152550 | 49152420 | 49152420 | Missense_Mutation | G | A | p.T615I |
| A375_SKIN | 49152392 | 49152550 | 49152437 | 49152437 | Missense_Mutation | G | T | p.N609K |
| SNU1040_LARGE_INTESTINE | 49152392 | 49152550 | 49152447 | 49152447 | Missense_Mutation | C | T | p.R606H |
| LS411N_LARGE_INTESTINE | 49152392 | 49152550 | 49152511 | 49152511 | Missense_Mutation | C | T | p.A585T |
| 22RV1_PROSTATE | 49152392 | 49152550 | 49152519 | 49152519 | Missense_Mutation | G | A | p.T582I |
| JHOC5_OVARY | 49152392 | 49152550 | 49152527 | 49152527 | Missense_Mutation | G | C | p.S579R |
| NCIH358_LUNG | 49153713 | 49153784 | 49153723 | 49153723 | Missense_Mutation | C | A | p.V348L |
| IGROV1_OVARY | 49153884 | 49154040 | 49153917 | 49153917 | Missense_Mutation | C | T | p.R316H |
| FLO1_OESOPHAGUS | 49153884 | 49154040 | 49153963 | 49153963 | Missense_Mutation | C | T | p.V301M |
| UDSCC2_UPPER_AERODIGESTIVE_TRACT | 49153884 | 49154040 | 49153977 | 49153977 | Missense_Mutation | G | A | p.S296L |
| HUPT4_PANCREAS | 49153884 | 49154040 | 49154026 | 49154026 | Missense_Mutation | C | T | p.V280M |
| HDMYZ_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 49153884 | 49154040 | 49154035 | 49154035 | Missense_Mutation | C | T | p.E277K |
| SNU175_LARGE_INTESTINE | 49154870 | 49155003 | 49154920 | 49154920 | Missense_Mutation | G | A | p.H186Y |
| CORL23_LUNG | 49155380 | 49155553 | 49155427 | 49155427 | Missense_Mutation | G | A | p.S84L |
| NCIH2066_LUNG | 49155380 | 49155553 | 49155441 | 49155442 | Missense_Mutation | CC | AA | p.R79L |
| QGP1_PANCREAS | 49155380 | 49155553 | 49155442 | 49155442 | Missense_Mutation | C | T | p.R79Q |
| NCIH2066_LUNG | 49155380 | 49155553 | 49155442 | 49155442 | Missense_Mutation | C | A | p.R79L |
| TUHR10TKB_KIDNEY | 49155380 | 49155553 | 49155451 | 49155451 | Missense_Mutation | T | G | p.H76P |
| LU135_LUNG | 49155380 | 49155553 | 49155451 | 49155451 | Missense_Mutation | T | G | p.H76P |
| SKM1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 49155380 | 49155553 | 49155451 | 49155451 | Missense_Mutation | T | G | p.H76P |
| TCYIK_CERVIX | 49155380 | 49155553 | 49155451 | 49155451 | Missense_Mutation | T | G | p.H76P |
| YH13_CENTRAL_NERVOUS_SYSTEM | 49155380 | 49155553 | 49155451 | 49155451 | Missense_Mutation | T | G | p.H76P |
| NCIH2066_LUNG | 49155380 | 49155553 | 49155493 | 49155493 | Missense_Mutation | G | A | p.S62F |
| IPC298_SKIN | 49155380 | 49155553 | 49155497 | 49155497 | Missense_Mutation | G | A | p.P61S |
| MFE319_ENDOMETRIUM | 49155380 | 49155553 | 49155500 | 49155500 | Missense_Mutation | C | T | p.D60N |
| MOLT3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 49155380 | 49155553 | 49155508 | 49155508 | Missense_Mutation | G | T | p.A57D |
| SNU719_STOMACH | 49152392 | 49152550 | 49152512 | 49152512 | Nonsense_Mutation | A | T | p.Y584* |
| NCIH1155_LUNG | 49153713 | 49153784 | 49153726 | 49153726 | Nonsense_Mutation | G | A | p.Q347* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for USP19 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for USP19 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for USP19 |
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RelatedDrugs for USP19 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for USP19 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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