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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for PRSS16 |
 Gene summary |
| Gene information | Gene symbol | PRSS16 | Gene ID | 10279 |
| Gene name | serine protease 16 | |
| Synonyms | TSSP | |
| Cytomap | 6p22.1 | |
| Type of gene | protein-coding | |
| Description | thymus-specific serine proteaseprotease, serine 16protease, serine, 16 (thymus)thymus specific serine peptidase | |
| Modification date | 20180523 | |
| UniProtAcc | Q9NQE7 | |
| Context | PubMed: PRSS16 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for PRSS16 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for PRSS16 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for PRSS16 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_448721 | 6 | 27215509:27215586:27215660:27215827:27220586:27220728 | 27215660:27215827 | ENSG00000112812.11 | ENST00000421826.2 |
| exon_skip_448722 | 6 | 27215509:27215586:27215660:27215827:27222471:27222478 | 27215660:27215827 | ENSG00000112812.11 | ENST00000466364.1 |
| exon_skip_448746 | 6 | 27215673:27215827:27216625:27216725:27216878:27217008 | 27216625:27216725 | ENSG00000112812.11 | ENST00000470870.1,ENST00000230582.3 |
| exon_skip_448747 | 6 | 27215673:27215827:27216625:27216725:27220586:27220728 | 27216625:27216725 | ENSG00000112812.11 | ENST00000454665.2 |
| exon_skip_448758 | 6 | 27215673:27215827:27216878:27217008:27220586:27220728 | 27216878:27217008 | ENSG00000112812.11 | ENST00000468930.1 |
| exon_skip_448776 | 6 | 27215673:27215827:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000421826.2 |
| exon_skip_448783 | 6 | 27215673:27215827:27222471:27222651:27222764:27222898 | 27222471:27222651 | ENSG00000112812.11 | ENST00000466364.1 |
| exon_skip_448787 | 6 | 27216714:27216725:27216878:27217008:27220586:27220728 | 27216878:27217008 | ENSG00000112812.11 | ENST00000470870.1 |
| exon_skip_448794 | 6 | 27216714:27216725:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000454665.2 |
| exon_skip_448814 | 6 | 27216878:27217008:27218461:27218585:27218820:27218898 | 27218461:27218585 | ENSG00000112812.11 | ENST00000475106.1,ENST00000230582.3 |
| exon_skip_448816 | 6 | 27216878:27217008:27218461:27218585:27220586:27220728 | 27218461:27218585 | ENSG00000112812.11 | ENST00000485993.1 |
| exon_skip_448832 | 6 | 27216878:27217008:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000470870.1,ENST00000468930.1 |
| exon_skip_448845 | 6 | 27218524:27218585:27218820:27218898:27218995:27219043 | 27218820:27218898 | ENSG00000112812.11 | ENST00000230582.3 |
| exon_skip_448846 | 6 | 27218524:27218585:27218820:27218898:27220586:27220728 | 27218820:27218898 | ENSG00000112812.11 | ENST00000475106.1 |
| exon_skip_448853 | 6 | 27218820:27218898:27218995:27219043:27219528:27219819 | 27218995:27219043 | ENSG00000112812.11 | ENST00000230582.3 |
| exon_skip_448856 | 6 | 27218995:27219043:27219528:27219819:27220586:27220728 | 27219528:27219819 | ENSG00000112812.11 | ENST00000481125.1,ENST00000230582.3 |
| exon_skip_448859 | 6 | 27218995:27219043:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000488649.1 |
| exon_skip_448860 | 6 | 27218995:27219043:27220586:27220728:27222764:27222898 | 27220586:27220728 | ENSG00000112812.11 | ENST00000492575.1 |
| exon_skip_448865 | 6 | 27219100:27219280:27220586:27220728:27222764:27222910 | 27220586:27220728 | ENSG00000112812.11 | ENST00000459736.1 |
| exon_skip_448867 | 6 | 27219528:27219819:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000230582.3,ENST00000468138.1 |
| exon_skip_448869 | 6 | 27219528:27219819:27220586:27220728:27222764:27222898 | 27220586:27220728 | ENSG00000112812.11 | ENST00000481125.1 |
| exon_skip_448874 | 6 | 27219528:27219819:27222471:27222651:27222764:27222898 | 27222471:27222651 | ENSG00000112812.11 | ENST00000471463.1 |
| exon_skip_448879 | 6 | 27220586:27220728:27222471:27222651:27222764:27222898 | 27222471:27222651 | ENSG00000112812.11 | ENST00000488649.1,ENST00000230582.3,ENST00000484493.1,ENST00000421826.2,ENST00000454665.2,ENST00000468138.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for PRSS16 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_448856 | 6 | 27218995:27219043:27219528:27219819:27220586:27220728 | 27219528:27219819 | ENSG00000112812.11 | ENST00000230582.3,ENST00000481125.1 |
| exon_skip_448859 | 6 | 27218995:27219043:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000488649.1 |
| exon_skip_448860 | 6 | 27218995:27219043:27220586:27220728:27222764:27222898 | 27220586:27220728 | ENSG00000112812.11 | ENST00000492575.1 |
| exon_skip_448865 | 6 | 27219100:27219280:27220586:27220728:27222764:27222910 | 27220586:27220728 | ENSG00000112812.11 | ENST00000459736.1 |
| exon_skip_448867 | 6 | 27219528:27219819:27220586:27220728:27222471:27222478 | 27220586:27220728 | ENSG00000112812.11 | ENST00000230582.3,ENST00000468138.1 |
| exon_skip_448869 | 6 | 27219528:27219819:27220586:27220728:27222764:27222898 | 27220586:27220728 | ENSG00000112812.11 | ENST00000481125.1 |
| exon_skip_448874 | 6 | 27219528:27219819:27222471:27222651:27222764:27222898 | 27222471:27222651 | ENSG00000112812.11 | ENST00000471463.1 |
| exon_skip_448879 | 6 | 27220586:27220728:27222471:27222651:27222764:27222898 | 27222471:27222651 | ENSG00000112812.11 | ENST00000454665.2,ENST00000421826.2,ENST00000230582.3,ENST00000488649.1,ENST00000484493.1,ENST00000468138.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for PRSS16 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000230582 | 27216625 | 27216725 | Frame-shift |
| ENST00000230582 | 27218461 | 27218585 | Frame-shift |
| ENST00000230582 | 27220586 | 27220728 | Frame-shift |
| ENST00000230582 | 27218820 | 27218898 | In-frame |
| ENST00000230582 | 27218995 | 27219043 | In-frame |
| ENST00000230582 | 27219528 | 27219819 | In-frame |
| ENST00000230582 | 27222471 | 27222651 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000230582 | 27220586 | 27220728 | Frame-shift |
| ENST00000230582 | 27219528 | 27219819 | In-frame |
| ENST00000230582 | 27222471 | 27222651 | In-frame |
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Infer the effects of exon skipping event on protein functional features for PRSS16 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000230582 | 2733 | 514 | 27218820 | 27218898 | 607 | 684 | 197 | 223 |
| ENST00000230582 | 2733 | 514 | 27218995 | 27219043 | 685 | 732 | 223 | 239 |
| ENST00000230582 | 2733 | 514 | 27219528 | 27219819 | 733 | 1023 | 239 | 336 |
| ENST00000230582 | 2733 | 514 | 27222471 | 27222651 | 1166 | 1345 | 383 | 443 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000230582 | 2733 | 514 | 27219528 | 27219819 | 733 | 1023 | 239 | 336 |
| ENST00000230582 | 2733 | 514 | 27222471 | 27222651 | 1166 | 1345 | 383 | 443 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9NQE7 | 197 | 223 | 25 | 514 | Chain | ID=PRO_0000027320;Note=Thymus-specific serine protease |
| Q9NQE7 | 197 | 223 | 204 | 204 | Natural variant | ID=VAR_051827;Note=A->G;Dbxref=dbSNP:rs35466700 |
| Q9NQE7 | 223 | 239 | 25 | 514 | Chain | ID=PRO_0000027320;Note=Thymus-specific serine protease |
| Q9NQE7 | 239 | 336 | 25 | 514 | Chain | ID=PRO_0000027320;Note=Thymus-specific serine protease |
| Q9NQE7 | 239 | 336 | 321 | 321 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q9NQE7 | 383 | 443 | 25 | 514 | Chain | ID=PRO_0000027320;Note=Thymus-specific serine protease |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9NQE7 | 239 | 336 | 25 | 514 | Chain | ID=PRO_0000027320;Note=Thymus-specific serine protease |
| Q9NQE7 | 239 | 336 | 321 | 321 | Glycosylation | Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q9NQE7 | 383 | 443 | 25 | 514 | Chain | ID=PRO_0000027320;Note=Thymus-specific serine protease |
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SNVs in the skipped exons for PRSS16 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_448747 exon_skip_448746 | 27216626 | 27216725 | 27216628 | 27216628 | Frame_Shift_Del | T | - | p.R80fs |
| STAD | TCGA-HU-A4GT-01 | exon_skip_448845 exon_skip_448846 | 27218821 | 27218898 | 27218823 | 27218823 | Frame_Shift_Del | C | - | p.F198fs |
| COAD | TCGA-AZ-6598-01 | exon_skip_448856 | 27219529 | 27219819 | 27219760 | 27219760 | Frame_Shift_Del | G | - | p.L316fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_448776 exon_skip_448832 exon_skip_448794 exon_skip_448860 exon_skip_448859 exon_skip_448867 exon_skip_448865 exon_skip_448869 | 27220587 | 27220728 | 27220623 | 27220623 | Frame_Shift_Del | T | - | p.F349fs |
| SKCM | TCGA-FS-A4F8-06 | exon_skip_448721 exon_skip_448722 | 27215661 | 27215827 | 27215684 | 27215684 | Nonsense_Mutation | G | T | p.E32* |
| SKCM | TCGA-FS-A4F8-06 | exon_skip_448721 exon_skip_448722 | 27215661 | 27215827 | 27215684 | 27215684 | Nonsense_Mutation | G | T | p.E32X |
| LUAD | TCGA-05-5428-01 | exon_skip_448747 exon_skip_448746 | 27216626 | 27216725 | 27216634 | 27216634 | Nonsense_Mutation | G | A | p.W82* |
| SKCM | TCGA-GN-A4U4-06 | exon_skip_448747 exon_skip_448746 | 27216626 | 27216725 | 27216652 | 27216652 | Nonsense_Mutation | G | A | p.W88* |
| SKCM | TCGA-D3-A3C3-06 | exon_skip_448787 exon_skip_448758 | 27216879 | 27217008 | 27216906 | 27216906 | Nonsense_Mutation | G | A | p.W122* |
| SKCM | TCGA-W3-AA21-06 | exon_skip_448787 exon_skip_448758 | 27216879 | 27217008 | 27216980 | 27216980 | Nonsense_Mutation | C | T | p.Q147* |
| LIHC | TCGA-FV-A495-01 | exon_skip_448776 exon_skip_448832 exon_skip_448794 exon_skip_448860 exon_skip_448859 exon_skip_448867 exon_skip_448865 exon_skip_448869 | 27220587 | 27220728 | 27220730 | 27220730 | Splice_Site | T | C | . |
| PAAD | TCGA-IB-7651-01 | exon_skip_448874 exon_skip_448879 exon_skip_448783 | 27222472 | 27222651 | 27222471 | 27222471 | Splice_Site | G | T | . |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-IB-7651-01 |
| Cancer type: PAAD | |
| ESID: exon_skip_448783 | |
| Skipped exon start: 27222472 | |
| Skipped exon end: 27222651 | |
| Mutation start: 27222471 | |
| Mutation end: 27222471 | |
| Mutation type: Splice_Site | |
| Reference seq: G | |
| Mutation seq: T | |
| AAchange: . | |
exon_skip_113241_PAAD_TCGA-IB-7651-01.png | |
exon_skip_115380_PAAD_TCGA-IB-7651-01.png | |
exon_skip_124564_PAAD_TCGA-IB-7651-01.png | |
exon_skip_135806_PAAD_TCGA-IB-7651-01.png | |
exon_skip_139341_PAAD_TCGA-IB-7651-01.png | |
exon_skip_153733_PAAD_TCGA-IB-7651-01.png | |
exon_skip_155805_PAAD_TCGA-IB-7651-01.png | |
exon_skip_18053_PAAD_TCGA-IB-7651-01.png | |
exon_skip_18056_PAAD_TCGA-IB-7651-01.png | |
exon_skip_23067_PAAD_TCGA-IB-7651-01.png | |
exon_skip_287059_PAAD_TCGA-IB-7651-01.png | |
exon_skip_294631_PAAD_TCGA-IB-7651-01.png | |
exon_skip_298512_PAAD_TCGA-IB-7651-01.png | |
exon_skip_306900_PAAD_TCGA-IB-7651-01.png | |
exon_skip_307723_PAAD_TCGA-IB-7651-01.png | |
exon_skip_315960_PAAD_TCGA-IB-7651-01.png | |
exon_skip_324675_PAAD_TCGA-IB-7651-01.png | |
exon_skip_330351_PAAD_TCGA-IB-7651-01.png | |
exon_skip_334330_PAAD_TCGA-IB-7651-01.png | |
exon_skip_341784_PAAD_TCGA-IB-7651-01.png | |
exon_skip_343314_PAAD_TCGA-IB-7651-01.png | |
exon_skip_348329_PAAD_TCGA-IB-7651-01.png | |
exon_skip_354232_PAAD_TCGA-IB-7651-01.png | |
exon_skip_370626_PAAD_TCGA-IB-7651-01.png | |
exon_skip_377740_PAAD_TCGA-IB-7651-01.png | |
exon_skip_385032_PAAD_TCGA-IB-7651-01.png | |
exon_skip_390031_PAAD_TCGA-IB-7651-01.png | |
exon_skip_422548_PAAD_TCGA-IB-7651-01.png | |
exon_skip_424536_PAAD_TCGA-IB-7651-01.png | |
exon_skip_431753_PAAD_TCGA-IB-7651-01.png | |
exon_skip_432982_PAAD_TCGA-IB-7651-01.png | |
exon_skip_435489_PAAD_TCGA-IB-7651-01.png | |
exon_skip_435729_PAAD_TCGA-IB-7651-01.png | |
exon_skip_441705_PAAD_TCGA-IB-7651-01.png | |
exon_skip_448879_PAAD_TCGA-IB-7651-01.png | |
exon_skip_468347_PAAD_TCGA-IB-7651-01.png | |
exon_skip_494000_PAAD_TCGA-IB-7651-01.png | |
exon_skip_494029_PAAD_TCGA-IB-7651-01.png | |
exon_skip_499410_PAAD_TCGA-IB-7651-01.png | |
exon_skip_499695_PAAD_TCGA-IB-7651-01.png | |
exon_skip_499697_PAAD_TCGA-IB-7651-01.png | |
exon_skip_79905_PAAD_TCGA-IB-7651-01.png | |
exon_skip_80096_PAAD_TCGA-IB-7651-01.png | |
exon_skip_95924_PAAD_TCGA-IB-7651-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| NCIH2073_LUNG | 27216626 | 27216725 | 27216668 | 27216668 | Frame_Shift_Del | C | - | p.P94fs |
| COLO792_SKIN | 27215661 | 27215827 | 27215673 | 27215674 | Missense_Mutation | GG | AA | p.R28K |
| DETROIT562_UPPER_AERODIGESTIVE_TRACT | 27215661 | 27215827 | 27215675 | 27215675 | Missense_Mutation | C | T | p.R29C |
| HCC33_LUNG | 27215661 | 27215827 | 27215722 | 27215723 | Missense_Mutation | CC | AA | p.L45M |
| HCC33_LUNG | 27215661 | 27215827 | 27215723 | 27215723 | Missense_Mutation | C | A | p.L45M |
| MDAMB175VII_BREAST | 27215661 | 27215827 | 27215814 | 27215814 | Missense_Mutation | G | A | p.R75Q |
| EB2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 27215661 | 27215827 | 27215814 | 27215814 | Missense_Mutation | G | A | p.R75Q |
| SNU81_LARGE_INTESTINE | 27215661 | 27215827 | 27215822 | 27215822 | Missense_Mutation | C | A | p.L78I |
| SW900_LUNG | 27216626 | 27216725 | 27216683 | 27216683 | Missense_Mutation | C | G | p.L99V |
| NCIH1105_LUNG | 27216626 | 27216725 | 27216711 | 27216711 | Missense_Mutation | G | T | p.G108V |
| NCIH1105_LUNG | 27216626 | 27216725 | 27216711 | 27216712 | Missense_Mutation | GC | TA | p.G108V |
| YD38_UPPER_AERODIGESTIVE_TRACT | 27216879 | 27217008 | 27216883 | 27216883 | Missense_Mutation | T | A | p.H114Q |
| LS411N_LARGE_INTESTINE | 27216879 | 27217008 | 27216887 | 27216887 | Missense_Mutation | G | A | p.A116T |
| COGN278_AUTONOMIC_GANGLIA | 27216879 | 27217008 | 27216890 | 27216890 | Missense_Mutation | G | T | p.A117S |
| OE33_OESOPHAGUS | 27216879 | 27217008 | 27216925 | 27216925 | Missense_Mutation | C | A | p.S128R |
| CHLA258_BONE | 27216879 | 27217008 | 27216986 | 27216986 | Missense_Mutation | C | T | p.R149C |
| UMC11_LUNG | 27216879 | 27217008 | 27216987 | 27216987 | Missense_Mutation | G | A | p.R149H |
| NCIH1694_LUNG | 27216879 | 27217008 | 27217003 | 27217004 | Missense_Mutation | CC | AG | p.L155V |
| NCIH1694_LUNG | 27216879 | 27217008 | 27217004 | 27217004 | Missense_Mutation | C | G | p.L155V |
| WM88_SKIN | 27218462 | 27218585 | 27218575 | 27218575 | Missense_Mutation | C | T | p.A194V |
| SNU81_LARGE_INTESTINE | 27218821 | 27218898 | 27218883 | 27218883 | Missense_Mutation | C | A | p.F218L |
| HO1U1_UPPER_AERODIGESTIVE_TRACT | 27218996 | 27219043 | 27219003 | 27219003 | Missense_Mutation | C | T | p.S226F |
| NCIH647_LUNG | 27218996 | 27219043 | 27219006 | 27219006 | Missense_Mutation | G | A | p.R227Q |
| CMLT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 27218996 | 27219043 | 27219023 | 27219023 | Missense_Mutation | G | A | p.A233T |
| NCIH2342_LUNG | 27219529 | 27219819 | 27219565 | 27219565 | Missense_Mutation | G | C | p.E252Q |
| PCI6A_UPPER_AERODIGESTIVE_TRACT | 27219529 | 27219819 | 27219673 | 27219674 | Missense_Mutation | CT | AG | p.L288R |
| MDAMB361_BREAST | 27219529 | 27219819 | 27219805 | 27219805 | Missense_Mutation | C | T | p.R332C |
| DANG_PANCREAS | 27220587 | 27220728 | 27220629 | 27220629 | Missense_Mutation | C | G | p.R351G |
| OV7_OVARY | 27220587 | 27220728 | 27220716 | 27220716 | Missense_Mutation | G | A | p.E380K |
| AMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 27220587 | 27220728 | 27220722 | 27220722 | Missense_Mutation | G | A | p.G382S |
| MCC26_SKIN | 27222472 | 27222651 | 27222595 | 27222595 | Missense_Mutation | C | T | p.T425M |
| HCC2108_LUNG | 27222472 | 27222651 | 27222625 | 27222625 | Missense_Mutation | G | A | p.G435E |
| NCIH82_LUNG | 27222472 | 27222651 | 27222648 | 27222648 | Missense_Mutation | A | T | p.N443Y |
| NCIH2110_LUNG | 27215661 | 27215827 | 27215693 | 27215693 | Nonsense_Mutation | C | T | p.Q35* |
| NCIH510_LUNG | 27216626 | 27216725 | 27216633 | 27216633 | Nonsense_Mutation | G | A | p.W82* |
| SW780_URINARY_TRACT | 27218462 | 27218585 | 27218573 | 27218573 | Nonsense_Mutation | G | A | p.W193* |
| HCC2998_LARGE_INTESTINE | 27216626 | 27216725 | 27216627 | 27216627 | Splice_Site | G | A | p.R80H |
| CAL27_UPPER_AERODIGESTIVE_TRACT | 27216626 | 27216725 | 27216724 | 27216724 | Splice_Site | A | C | p.R112S |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PRSS16 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PRSS16 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PRSS16 |
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RelatedDrugs for PRSS16 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PRSS16 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| PRSS16 | C0036341 | Schizophrenia | 2 | PSYGENET |
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