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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for UBXN11 |
 Gene summary |
| Gene information | Gene symbol | UBXN11 | Gene ID | 91544 |
| Gene name | UBX domain protein 11 | |
| Synonyms | COA-1|PP2243|SOC|SOCI|UBXD5 | |
| Cytomap | 1p36.11 | |
| Type of gene | protein-coding | |
| Description | UBX domain-containing protein 11UBX domain-containing protein 5colorectal tumor-associated antigen COA-1colorectal tumor-associated antigen-1socius | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for UBXN11 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000158062
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | DOWN | ENST00000374223.5 | UBXN11-207:protein_coding:UBXN11 | 1.063393e+02 | -1.056363e+00 | 2.641226e-09 | 9.850204e-08 |
| CB | DOWN | ENST00000494942.5 | UBXN11-215:retained_intron:UBXN11 | 1.674399e+02 | -8.741081e-01 | 2.436837e-08 | 6.420589e-07 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for UBXN11 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
 |
| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_114150 | chr1 | 26285943:26286037:26294205:26294331:26297427:26297481 | 26294205:26294331 |
| exon_skip_1216 | chr1 | 26294205:26294331:26297427:26297481:26297962:26298026 | 26297427:26297481 |
| exon_skip_123068 | chr1 | 26285943:26286037:26294205:26294331:26296919:26296932 | 26294205:26294331 |
| exon_skip_142675 | chr1 | 26297962:26298062:26300926:26301053:26301694:26301722 | 26300926:26301053 |
| exon_skip_144874 | chr1 | 26297962:26298062:26300926:26301024:26301694:26301722 | 26300926:26301024 |
| exon_skip_1855 | chr1 | 26294205:26294331:26296919:26296995:26297427:26297481 | 26296919:26296995 |
| exon_skip_186575 | chr1 | 26282649:26282789:26282864:26282937:26284142:26284245 | 26282864:26282937 |
| exon_skip_210586 | chr1 | 26284362:26284482:26285464:26285541:26285823:26286037 | 26285464:26285541 |
| exon_skip_21757 | chr1 | 26282864:26282937:26284142:26284245:26284362:26284482 | 26284142:26284245 |
| exon_skip_235493 | chr1 | 26297962:26298062:26301694:26301722:26306592:26306609 | 26301694:26301722 |
| exon_skip_245793 | chr1 | 26297962:26298062:26300926:26301053:26301694:26301719 | 26300926:26301053 |
| exon_skip_260063 | chr1 | 26282864:26282937:26284142:26284281:26284362:26285541 | 26284142:26284281 |
| exon_skip_265966 | chr1 | 26282864:26282937:26284142:26284245:26284362:26284461 | 26284142:26284245 |
| exon_skip_269328 | chr1 | 26302813:26302918:26303043:26303167:26306592:26306609 | 26303043:26303167 |
| exon_skip_272356 | chr1 | 26285943:26286037:26300926:26301024:26301694:26301719 | 26300926:26301024 |
| exon_skip_275487 | chr1 | 26301694:26301722:26302813:26302918:26303043:26303167 | 26302813:26302918 |
| exon_skip_283239 | chr1 | 26285943:26286037:26300926:26301024:26301694:26301722 | 26300926:26301024 |
| exon_skip_41466 | chr1 | 26297962:26298062:26300926:26301024:26301694:26301719 | 26300926:26301024 |
| exon_skip_49286 | chr1 | 26297995:26298062:26300926:26301024:26301694:26301722 | 26300926:26301024 |
| exon_skip_55416 | chr1 | 26301694:26301722:26302813:26302918:26306592:26306609 | 26302813:26302918 |
| exon_skip_71550 | chr1 | 26282864:26282937:26284142:26284281:26284362:26284482 | 26284142:26284281 |
| exon_skip_754 | chr1 | 26285943:26286037:26294205:26294331:26296919:26296995 | 26294205:26294331 |
| exon_skip_76926 | chr1 | 26297995:26298062:26301694:26301722:26306592:26306609 | 26301694:26301722 |
| exon_skip_88754 | chr1 | 26285943:26286037:26296919:26296995:26297427:26297481 | 26296919:26296995 |
| exon_skip_90247 | chr1 | 26296947:26296995:26297427:26297481:26297962:26298026 | 26297427:26297481 |
| exon_skip_90885 | chr1 | 26297995:26298062:26300926:26301053:26301694:26301722 | 26300926:26301053 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for UBXN11 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000374221 | 26302813 | 26302918 | 3UTR-3CDS |
| ENST00000374222 | 26302813 | 26302918 | 3UTR-3CDS |
| ENST00000374221 | 26303043 | 26303167 | 3UTR-3UTR |
| ENST00000374221 | 26282864 | 26282937 | Frame-shift |
| ENST00000374222 | 26282864 | 26282937 | Frame-shift |
| ENST00000374221 | 26284142 | 26284245 | Frame-shift |
| ENST00000374222 | 26284142 | 26284245 | Frame-shift |
| ENST00000374221 | 26294205 | 26294331 | Frame-shift |
| ENST00000374222 | 26294205 | 26294331 | Frame-shift |
| ENST00000374221 | 26296919 | 26296995 | Frame-shift |
| ENST00000374222 | 26296919 | 26296995 | Frame-shift |
| ENST00000374221 | 26297427 | 26297481 | Frame-shift |
| ENST00000374222 | 26297427 | 26297481 | Frame-shift |
| ENST00000374221 | 26285464 | 26285541 | In-frame |
| ENST00000374222 | 26285464 | 26285541 | In-frame |
| ENST00000374221 | 26300926 | 26301024 | In-frame |
| ENST00000374222 | 26300926 | 26301024 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000374222 | 26302813 | 26302918 | 3UTR-3CDS |
| ENST00000374221 | 26284142 | 26284245 | Frame-shift |
| ENST00000374222 | 26284142 | 26284245 | Frame-shift |
| ENST00000374221 | 26294205 | 26294331 | Frame-shift |
| ENST00000374222 | 26294205 | 26294331 | Frame-shift |
| ENST00000374221 | 26285464 | 26285541 | In-frame |
| ENST00000374222 | 26285464 | 26285541 | In-frame |
| ENST00000374221 | 26300926 | 26301024 | In-frame |
| ENST00000374222 | 26300926 | 26301024 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000374221 | 26302813 | 26302918 | 3UTR-3CDS |
| ENST00000374222 | 26302813 | 26302918 | 3UTR-3CDS |
| ENST00000374221 | 26303043 | 26303167 | 3UTR-3UTR |
| ENST00000374221 | 26282864 | 26282937 | Frame-shift |
| ENST00000374222 | 26282864 | 26282937 | Frame-shift |
| ENST00000374221 | 26284142 | 26284245 | Frame-shift |
| ENST00000374222 | 26284142 | 26284245 | Frame-shift |
| ENST00000374221 | 26294205 | 26294331 | Frame-shift |
| ENST00000374222 | 26294205 | 26294331 | Frame-shift |
| ENST00000374221 | 26296919 | 26296995 | Frame-shift |
| ENST00000374222 | 26296919 | 26296995 | Frame-shift |
| ENST00000374221 | 26297427 | 26297481 | Frame-shift |
| ENST00000374222 | 26297427 | 26297481 | Frame-shift |
| ENST00000374221 | 26285464 | 26285541 | In-frame |
| ENST00000374222 | 26285464 | 26285541 | In-frame |
| ENST00000374221 | 26300926 | 26301024 | In-frame |
| ENST00000374222 | 26300926 | 26301024 | In-frame |
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Infer the effects of exon skipping event on protein functional features for UBXN11 |
p-ENSG00000158062_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000374221 | 1809 | 520 | 26300926 | 26301024 | 315 | 412 | 33 | 66 |
| ENST00000374222 | 2060 | 520 | 26300926 | 26301024 | 566 | 663 | 33 | 66 |
| ENST00000374221 | 1809 | 520 | 26285464 | 26285541 | 989 | 1065 | 258 | 283 |
| ENST00000374222 | 2060 | 520 | 26285464 | 26285541 | 1240 | 1316 | 258 | 283 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000374221 | 1809 | 520 | 26300926 | 26301024 | 315 | 412 | 33 | 66 |
| ENST00000374222 | 2060 | 520 | 26300926 | 26301024 | 566 | 663 | 33 | 66 |
| ENST00000374221 | 1809 | 520 | 26285464 | 26285541 | 989 | 1065 | 258 | 283 |
| ENST00000374222 | 2060 | 520 | 26285464 | 26285541 | 1240 | 1316 | 258 | 283 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000374221 | 1809 | 520 | 26300926 | 26301024 | 315 | 412 | 33 | 66 |
| ENST00000374222 | 2060 | 520 | 26300926 | 26301024 | 566 | 663 | 33 | 66 |
| ENST00000374221 | 1809 | 520 | 26285464 | 26285541 | 989 | 1065 | 258 | 283 |
| ENST00000374222 | 2060 | 520 | 26285464 | 26285541 | 1240 | 1316 | 258 | 283 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q5T124 | 33 | 66 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 33 | 66 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 33 | 66 | 1 | 75 | Alternative sequence | ID=VSP_024772;Note=In isoform 8. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14583468,ECO:0000303|Ref.2;Dbxref=PMID:14583468 |
| Q5T124 | 33 | 66 | 1 | 75 | Alternative sequence | ID=VSP_024772;Note=In isoform 8. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14583468,ECO:0000303|Ref.2;Dbxref=PMID:14583468 |
| Q5T124 | 33 | 66 | 1 | 38 | Alternative sequence | ID=VSP_024773;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q5T124 | 33 | 66 | 1 | 38 | Alternative sequence | ID=VSP_024773;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q5T124 | 33 | 66 | 34 | 66 | Alternative sequence | ID=VSP_024774;Note=In isoform 2 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005,ECO:0000303|Ref.2;Dbxref=PMID:14702039,PMID:17974005 |
| Q5T124 | 33 | 66 | 34 | 66 | Alternative sequence | ID=VSP_024774;Note=In isoform 2 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005,ECO:0000303|Ref.2;Dbxref=PMID:14702039,PMID:17974005 |
| Q5T124 | 33 | 66 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 33 | 66 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 258 | 283 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 258 | 283 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 230 | 294 | Domain | Note=SEP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00732 |
| Q5T124 | 258 | 283 | 230 | 294 | Domain | Note=SEP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00732 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q5T124 | 33 | 66 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 33 | 66 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 33 | 66 | 1 | 75 | Alternative sequence | ID=VSP_024772;Note=In isoform 8. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14583468,ECO:0000303|Ref.2;Dbxref=PMID:14583468 |
| Q5T124 | 33 | 66 | 1 | 75 | Alternative sequence | ID=VSP_024772;Note=In isoform 8. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14583468,ECO:0000303|Ref.2;Dbxref=PMID:14583468 |
| Q5T124 | 33 | 66 | 1 | 38 | Alternative sequence | ID=VSP_024773;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q5T124 | 33 | 66 | 1 | 38 | Alternative sequence | ID=VSP_024773;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q5T124 | 33 | 66 | 34 | 66 | Alternative sequence | ID=VSP_024774;Note=In isoform 2 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005,ECO:0000303|Ref.2;Dbxref=PMID:14702039,PMID:17974005 |
| Q5T124 | 33 | 66 | 34 | 66 | Alternative sequence | ID=VSP_024774;Note=In isoform 2 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005,ECO:0000303|Ref.2;Dbxref=PMID:14702039,PMID:17974005 |
| Q5T124 | 33 | 66 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 33 | 66 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 258 | 283 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 258 | 283 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 230 | 294 | Domain | Note=SEP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00732 |
| Q5T124 | 258 | 283 | 230 | 294 | Domain | Note=SEP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00732 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q5T124 | 33 | 66 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 33 | 66 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 33 | 66 | 1 | 75 | Alternative sequence | ID=VSP_024772;Note=In isoform 8. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14583468,ECO:0000303|Ref.2;Dbxref=PMID:14583468 |
| Q5T124 | 33 | 66 | 1 | 75 | Alternative sequence | ID=VSP_024772;Note=In isoform 8. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14583468,ECO:0000303|Ref.2;Dbxref=PMID:14583468 |
| Q5T124 | 33 | 66 | 1 | 38 | Alternative sequence | ID=VSP_024773;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q5T124 | 33 | 66 | 1 | 38 | Alternative sequence | ID=VSP_024773;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q5T124 | 33 | 66 | 34 | 66 | Alternative sequence | ID=VSP_024774;Note=In isoform 2 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005,ECO:0000303|Ref.2;Dbxref=PMID:14702039,PMID:17974005 |
| Q5T124 | 33 | 66 | 34 | 66 | Alternative sequence | ID=VSP_024774;Note=In isoform 2 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:17974005,ECO:0000303|Ref.2;Dbxref=PMID:14702039,PMID:17974005 |
| Q5T124 | 33 | 66 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 33 | 66 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 258 | 283 | 1 | 312 | Alternative sequence | ID=VSP_024771;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15498874;Dbxref=PMID:15498874 |
| Q5T124 | 258 | 283 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 1 | 520 | Chain | ID=PRO_0000284921;Note=UBX domain-containing protein 11 |
| Q5T124 | 258 | 283 | 230 | 294 | Domain | Note=SEP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00732 |
| Q5T124 | 258 | 283 | 230 | 294 | Domain | Note=SEP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00732 |
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3'-UTR located exon skipping events that lost miRNA binding sites in UBXN11 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000374221 | 26303043 | 26303167 | hsa-miR-1295b-5p | chr1:26303104-26303111 | 8mer-1a | chr1:26303091-26303111 | 158.00 | -25.07 |
| Mayo | ENST00000374221 | 26303043 | 26303167 | hsa-miR-9902 | chr1:26303073-26303080 | 8mer-1a | chr1:26303059-26303080 | 151.00 | -16.93 |
| Mayo | ENST00000374221 | 26303043 | 26303167 | hsa-miR-6501-3p | chr1:26303122-26303129 | 8mer-1a | chr1:26303106-26303129 | 159.00 | -21.12 |
| Mayo | ENST00000374221 | 26303043 | 26303167 | hsa-miR-7114-5p | chr1:26303063-26303070 | 8mer-1a | chr1:26303051-26303070 | 150.00 | -21.99 |
| Mayo | ENST00000374221 | 26303043 | 26303167 | hsa-miR-1912-3p | chr1:26303104-26303111 | 8mer-1a | chr1:26303091-26303111 | 158.00 | -25.07 |
| ROSMAP | ENST00000374221 | 26303043 | 26303167 | hsa-miR-1295b-5p | chr1:26303104-26303111 | 8mer-1a | chr1:26303091-26303111 | 158.00 | -25.07 |
| ROSMAP | ENST00000374221 | 26303043 | 26303167 | hsa-miR-9902 | chr1:26303073-26303080 | 8mer-1a | chr1:26303059-26303080 | 151.00 | -16.93 |
| ROSMAP | ENST00000374221 | 26303043 | 26303167 | hsa-miR-6501-3p | chr1:26303122-26303129 | 8mer-1a | chr1:26303106-26303129 | 159.00 | -21.12 |
| ROSMAP | ENST00000374221 | 26303043 | 26303167 | hsa-miR-7114-5p | chr1:26303063-26303070 | 8mer-1a | chr1:26303051-26303070 | 150.00 | -21.99 |
| ROSMAP | ENST00000374221 | 26303043 | 26303167 | hsa-miR-1912-3p | chr1:26303104-26303111 | 8mer-1a | chr1:26303091-26303111 | 158.00 | -25.07 |
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SNVs in the skipped exons for UBXN11 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for UBXN11 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for UBXN11 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for UBXN11 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| HCC | RBM6 | exon_skip_76926 | -4.336726e-01 | 7.463589e-14 |
| HCC | HNRNPF | exon_skip_76926 | -4.394228e-01 | 3.199779e-14 |
| TC | HNRNPH2 | exon_skip_76926 | 4.054915e-01 | 1.658124e-07 |
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RelatedDrugs for UBXN11 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBXN11 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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