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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for UBL7 |
 Gene summary |
| Gene information | Gene symbol | UBL7 | Gene ID | 84993 |
| Gene name | ubiquitin like 7 | |
| Synonyms | BMSC-UbP|TCBA1 | |
| Cytomap | 15q24.1 | |
| Type of gene | protein-coding | |
| Description | ubiquitin-like protein 7ubiquitin-like 7 (bone marrow stromal cell-derived)ubiquitin-like protein SB132 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for UBL7 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000138629
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | UP | ENST00000567435.5 | UBL7-209:protein_coding:UBL7 | 1.662743e+02 | 1.057419e+00 | 1.706572e-15 | 8.887730e-13 |
| CB | DOWN | ENST00000565494.5 | UBL7-207:protein_coding:UBL7 | 3.593467e+01 | -8.830792e-01 | 2.951147e-08 | 7.562681e-07 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for UBL7 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_116216 | chr15 | 74445978:74446227:74448478:74448600:74449186:74449311 | 74448478:74448600 |
| exon_skip_15122 | chr15 | 74451436:74451520:74452296:74452378:74456552:74456671 | 74452296:74452378 |
| exon_skip_177477 | chr15 | 74458684:74458896:74460668:74460778:74461037:74461118 | 74460668:74460778 |
| exon_skip_192285 | chr15 | 74458841:74458896:74460668:74460778:74461037:74461118 | 74460668:74460778 |
| exon_skip_235461 | chr15 | 74450802:74450859:74452296:74452378:74456552:74456671 | 74452296:74452378 |
| exon_skip_243212 | chr15 | 74448478:74448600:74449186:74449353:74449626:74449675 | 74449186:74449353 |
| exon_skip_281914 | chr15 | 74458865:74458896:74460668:74460778:74461037:74461118 | 74460668:74460778 |
| exon_skip_62158 | chr15 | 74452296:74452378:74456552:74456671:74458684:74458896 | 74456552:74456671 |
| exon_skip_69282 | chr15 | 74450802:74450859:74451436:74451520:74452296:74452378 | 74451436:74451520 |
| exon_skip_92449 | chr15 | 74450802:74450859:74451436:74451520:74452296:74452377 | 74451436:74451520 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for UBL7 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000564488 | 74460668 | 74460778 | 3UTR-3UTR |
| ENST00000361351 | 74451436 | 74451520 | Frame-shift |
| ENST00000395081 | 74451436 | 74451520 | Frame-shift |
| ENST00000564488 | 74451436 | 74451520 | Frame-shift |
| ENST00000565335 | 74451436 | 74451520 | Frame-shift |
| ENST00000567435 | 74451436 | 74451520 | Frame-shift |
| ENST00000361351 | 74448478 | 74448600 | In-frame |
| ENST00000395081 | 74448478 | 74448600 | In-frame |
| ENST00000564488 | 74448478 | 74448600 | In-frame |
| ENST00000565335 | 74448478 | 74448600 | In-frame |
| ENST00000567435 | 74448478 | 74448600 | In-frame |
| ENST00000361351 | 74449186 | 74449353 | In-frame |
| ENST00000395081 | 74449186 | 74449353 | In-frame |
| ENST00000564488 | 74449186 | 74449353 | In-frame |
| ENST00000565335 | 74449186 | 74449353 | In-frame |
| ENST00000567435 | 74449186 | 74449353 | In-frame |
| ENST00000361351 | 74456552 | 74456671 | In-frame |
| ENST00000395081 | 74456552 | 74456671 | In-frame |
| ENST00000564488 | 74456552 | 74456671 | In-frame |
| ENST00000565335 | 74456552 | 74456671 | In-frame |
| ENST00000567435 | 74456552 | 74456671 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000564488 | 74460668 | 74460778 | 3UTR-3UTR |
| ENST00000361351 | 74456552 | 74456671 | In-frame |
| ENST00000395081 | 74456552 | 74456671 | In-frame |
| ENST00000564488 | 74456552 | 74456671 | In-frame |
| ENST00000565335 | 74456552 | 74456671 | In-frame |
| ENST00000567435 | 74456552 | 74456671 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000564488 | 74460668 | 74460778 | 3UTR-3UTR |
| ENST00000361351 | 74451436 | 74451520 | Frame-shift |
| ENST00000395081 | 74451436 | 74451520 | Frame-shift |
| ENST00000564488 | 74451436 | 74451520 | Frame-shift |
| ENST00000565335 | 74451436 | 74451520 | Frame-shift |
| ENST00000567435 | 74451436 | 74451520 | Frame-shift |
| ENST00000361351 | 74452296 | 74452378 | Frame-shift |
| ENST00000395081 | 74452296 | 74452378 | Frame-shift |
| ENST00000564488 | 74452296 | 74452378 | Frame-shift |
| ENST00000565335 | 74452296 | 74452378 | Frame-shift |
| ENST00000567435 | 74452296 | 74452378 | Frame-shift |
| ENST00000361351 | 74448478 | 74448600 | In-frame |
| ENST00000395081 | 74448478 | 74448600 | In-frame |
| ENST00000564488 | 74448478 | 74448600 | In-frame |
| ENST00000565335 | 74448478 | 74448600 | In-frame |
| ENST00000567435 | 74448478 | 74448600 | In-frame |
| ENST00000361351 | 74449186 | 74449353 | In-frame |
| ENST00000395081 | 74449186 | 74449353 | In-frame |
| ENST00000564488 | 74449186 | 74449353 | In-frame |
| ENST00000565335 | 74449186 | 74449353 | In-frame |
| ENST00000567435 | 74449186 | 74449353 | In-frame |
| ENST00000361351 | 74456552 | 74456671 | In-frame |
| ENST00000395081 | 74456552 | 74456671 | In-frame |
| ENST00000564488 | 74456552 | 74456671 | In-frame |
| ENST00000565335 | 74456552 | 74456671 | In-frame |
| ENST00000567435 | 74456552 | 74456671 | In-frame |
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Infer the effects of exon skipping event on protein functional features for UBL7 |
p-ENSG00000138629_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000361351 | 1377 | 380 | 74456552 | 74456671 | 289 | 407 | 61 | 101 |
| ENST00000395081 | 1444 | 380 | 74456552 | 74456671 | 356 | 474 | 61 | 101 |
| ENST00000564488 | 1494 | 380 | 74456552 | 74456671 | 407 | 525 | 61 | 101 |
| ENST00000565335 | 1431 | 380 | 74456552 | 74456671 | 343 | 461 | 61 | 101 |
| ENST00000567435 | 1737 | 380 | 74456552 | 74456671 | 649 | 767 | 61 | 101 |
| ENST00000361351 | 1377 | 380 | 74449186 | 74449353 | 819 | 985 | 238 | 293 |
| ENST00000395081 | 1444 | 380 | 74449186 | 74449353 | 886 | 1052 | 238 | 293 |
| ENST00000564488 | 1494 | 380 | 74449186 | 74449353 | 937 | 1103 | 238 | 293 |
| ENST00000565335 | 1431 | 380 | 74449186 | 74449353 | 873 | 1039 | 238 | 293 |
| ENST00000567435 | 1737 | 380 | 74449186 | 74449353 | 1179 | 1345 | 238 | 293 |
| ENST00000361351 | 1377 | 380 | 74448478 | 74448600 | 987 | 1108 | 294 | 334 |
| ENST00000395081 | 1444 | 380 | 74448478 | 74448600 | 1054 | 1175 | 294 | 334 |
| ENST00000564488 | 1494 | 380 | 74448478 | 74448600 | 1105 | 1226 | 294 | 334 |
| ENST00000565335 | 1431 | 380 | 74448478 | 74448600 | 1041 | 1162 | 294 | 334 |
| ENST00000567435 | 1737 | 380 | 74448478 | 74448600 | 1347 | 1468 | 294 | 334 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000361351 | 1377 | 380 | 74456552 | 74456671 | 289 | 407 | 61 | 101 |
| ENST00000395081 | 1444 | 380 | 74456552 | 74456671 | 356 | 474 | 61 | 101 |
| ENST00000564488 | 1494 | 380 | 74456552 | 74456671 | 407 | 525 | 61 | 101 |
| ENST00000565335 | 1431 | 380 | 74456552 | 74456671 | 343 | 461 | 61 | 101 |
| ENST00000567435 | 1737 | 380 | 74456552 | 74456671 | 649 | 767 | 61 | 101 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000361351 | 1377 | 380 | 74456552 | 74456671 | 289 | 407 | 61 | 101 |
| ENST00000395081 | 1444 | 380 | 74456552 | 74456671 | 356 | 474 | 61 | 101 |
| ENST00000564488 | 1494 | 380 | 74456552 | 74456671 | 407 | 525 | 61 | 101 |
| ENST00000565335 | 1431 | 380 | 74456552 | 74456671 | 343 | 461 | 61 | 101 |
| ENST00000567435 | 1737 | 380 | 74456552 | 74456671 | 649 | 767 | 61 | 101 |
| ENST00000361351 | 1377 | 380 | 74449186 | 74449353 | 819 | 985 | 238 | 293 |
| ENST00000395081 | 1444 | 380 | 74449186 | 74449353 | 886 | 1052 | 238 | 293 |
| ENST00000564488 | 1494 | 380 | 74449186 | 74449353 | 937 | 1103 | 238 | 293 |
| ENST00000565335 | 1431 | 380 | 74449186 | 74449353 | 873 | 1039 | 238 | 293 |
| ENST00000567435 | 1737 | 380 | 74449186 | 74449353 | 1179 | 1345 | 238 | 293 |
| ENST00000361351 | 1377 | 380 | 74448478 | 74448600 | 987 | 1108 | 294 | 334 |
| ENST00000395081 | 1444 | 380 | 74448478 | 74448600 | 1054 | 1175 | 294 | 334 |
| ENST00000564488 | 1494 | 380 | 74448478 | 74448600 | 1105 | 1226 | 294 | 334 |
| ENST00000565335 | 1431 | 380 | 74448478 | 74448600 | 1041 | 1162 | 294 | 334 |
| ENST00000567435 | 1737 | 380 | 74448478 | 74448600 | 1347 | 1468 | 294 | 334 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 61 | 101 | 18 | 98 | Domain | Note=Ubiquitin-like;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00214 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 262 | 262 | Sequence conflict | Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 238 | 293 | 272 | 272 | Sequence conflict | Note=L->R;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 1 | 380 | Chain | ID=PRO_0000211021;Note=Ubiquitin-like protein 7 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
| Q96S82 | 294 | 334 | 333 | 377 | Domain | Note=UBA;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00212 |
Top |
3'-UTR located exon skipping events that lost miRNA binding sites in UBL7 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000564488 | 74460668 | 74460778 | hsa-miR-6079 | chr15:74460763-74460770 | 8mer-1a | chr15:74460745-74460770 | 143.00 | -15.16 |
| Mayo | ENST00000564488 | 74460668 | 74460778 | hsa-miR-1251-3p | chr15:74460725-74460732 | 8mer-1a | chr15:74460722-74460745 | 156.00 | -15.64 |
| Mayo | ENST00000564488 | 74460668 | 74460778 | hsa-miR-4762-3p | chr15:74460696-74460703 | 8mer-1a | chr15:74460683-74460703 | 154.00 | -11.48 |
| Mayo | ENST00000564488 | 74460668 | 74460778 | hsa-miR-6828-5p | chr15:74460762-74460769 | 8mer-1a | chr15:74460746-74460769 | 151.00 | -15.24 |
| Mayo | ENST00000564488 | 74460668 | 74460778 | hsa-miR-29a-5p | chr15:74460694-74460701 | 8mer-1a | chr15:74460678-74460701 | 171.00 | -18.65 |
| MSBB | ENST00000564488 | 74460668 | 74460778 | hsa-miR-6079 | chr15:74460763-74460770 | 8mer-1a | chr15:74460745-74460770 | 143.00 | -15.16 |
| MSBB | ENST00000564488 | 74460668 | 74460778 | hsa-miR-1251-3p | chr15:74460725-74460732 | 8mer-1a | chr15:74460722-74460745 | 156.00 | -15.64 |
| MSBB | ENST00000564488 | 74460668 | 74460778 | hsa-miR-4762-3p | chr15:74460696-74460703 | 8mer-1a | chr15:74460683-74460703 | 154.00 | -11.48 |
| MSBB | ENST00000564488 | 74460668 | 74460778 | hsa-miR-6828-5p | chr15:74460762-74460769 | 8mer-1a | chr15:74460746-74460769 | 151.00 | -15.24 |
| MSBB | ENST00000564488 | 74460668 | 74460778 | hsa-miR-29a-5p | chr15:74460694-74460701 | 8mer-1a | chr15:74460678-74460701 | 171.00 | -18.65 |
| ROSMAP | ENST00000564488 | 74460668 | 74460778 | hsa-miR-6079 | chr15:74460763-74460770 | 8mer-1a | chr15:74460745-74460770 | 143.00 | -15.16 |
| ROSMAP | ENST00000564488 | 74460668 | 74460778 | hsa-miR-1251-3p | chr15:74460725-74460732 | 8mer-1a | chr15:74460722-74460745 | 156.00 | -15.64 |
| ROSMAP | ENST00000564488 | 74460668 | 74460778 | hsa-miR-4762-3p | chr15:74460696-74460703 | 8mer-1a | chr15:74460683-74460703 | 154.00 | -11.48 |
| ROSMAP | ENST00000564488 | 74460668 | 74460778 | hsa-miR-6828-5p | chr15:74460762-74460769 | 8mer-1a | chr15:74460746-74460769 | 151.00 | -15.24 |
| ROSMAP | ENST00000564488 | 74460668 | 74460778 | hsa-miR-29a-5p | chr15:74460694-74460701 | 8mer-1a | chr15:74460678-74460701 | 171.00 | -18.65 |
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SNVs in the skipped exons for UBL7 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for UBL7 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for UBL7 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for UBL7 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
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RelatedDrugs for UBL7 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBL7 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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