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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for PPFIBP1 |
 Gene summary |
| Gene information | Gene symbol | PPFIBP1 | Gene ID | 8496 |
| Gene name | PPFIA binding protein 1 | |
| Synonyms | L2|SGT2|hSGT2|hSgt2p | |
| Cytomap | 12p11.23-p11.22 | |
| Type of gene | protein-coding | |
| Description | liprin-beta-1PTPRF interacting protein, binding protein 1 (liprin beta 1)PTPRF-interacting protein-binding protein 1liprin related proteinprotein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for PPFIBP1 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000110841
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | UP | ENST00000542629.5 | PPFIBP1-215:protein_coding:PPFIBP1 | 2.223657e+01 | 1.445998e+00 | 2.316136e-03 | 1.040999e-02 |
| CB | UP | ENST00000537261.1 | PPFIBP1-206:protein_coding:PPFIBP1 | 3.394525e+00 | 8.394326e-01 | 7.090336e-03 | 2.621573e-02 |
| TC | UP | ENST00000542629.5 | PPFIBP1-215:protein_coding:PPFIBP1 | 1.213483e+01 | 1.646271e+00 | 9.621005e-06 | 2.515436e-04 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for PPFIBP1 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_133509 | chr12 | 27673767:27673827:27674192:27674221:27676428:27676557 | 27674192:27674221 |
| exon_skip_134421 | chr12 | 27654722:27654814:27655143:27655235:27656616:27656730 | 27655143:27655235 |
| exon_skip_152069 | chr12 | 27656616:27656730:27658816:27658848:27660884:27660945 | 27658816:27658848 |
| exon_skip_152328 | chr12 | 27682624:27682703:27687385:27687507:27688298:27688423 | 27687385:27687507 |
| exon_skip_166218 | chr12 | 27646062:27646148:27647729:27647842:27650010:27650052 | 27647729:27647842 |
| exon_skip_171808 | chr12 | 27646062:27646148:27647729:27647842:27650010:27650141 | 27647729:27647842 |
| exon_skip_216598 | chr12 | 27647729:27647842:27650010:27650141:27654722:27654814 | 27650010:27650141 |
| exon_skip_229983 | chr12 | 27676428:27676599:27677064:27677096:27679489:27679639 | 27677064:27677096 |
| exon_skip_84019 | chr12 | 27676428:27676599:27677064:27677096:27679489:27679617 | 27677064:27677096 |
| exon_skip_89289 | chr12 | 27656616:27656730:27660884:27660945:27664362:27664437 | 27660884:27660945 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_134421 | ROSMAP_PCC | 4.563281e-01 | 5.663529e-01 | -1.100248e-01 | 4.533028e-03 |
| exon_skip_134421 | MSBB_PG | 3.300000e-01 | 5.336170e-01 | -2.036170e-01 | 3.999252e-03 |
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Open reading frame (ORF) annotation in the exon skipping event for PPFIBP1 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000318304 | 27660884 | 27660945 | Frame-shift |
| ENST00000318304 | 27647729 | 27647842 | In-frame |
| ENST00000318304 | 27650010 | 27650141 | In-frame |
| ENST00000318304 | 27655143 | 27655235 | In-frame |
| ENST00000318304 | 27674192 | 27674221 | In-frame |
| ENST00000318304 | 27687385 | 27687507 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000318304 | 27660884 | 27660945 | Frame-shift |
| ENST00000318304 | 27650010 | 27650141 | In-frame |
| ENST00000318304 | 27655143 | 27655235 | In-frame |
| ENST00000318304 | 27674192 | 27674221 | In-frame |
| ENST00000318304 | 27687385 | 27687507 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000318304 | 27660884 | 27660945 | Frame-shift |
| ENST00000318304 | 27650010 | 27650141 | In-frame |
| ENST00000318304 | 27655143 | 27655235 | In-frame |
| ENST00000318304 | 27674192 | 27674221 | In-frame |
| ENST00000318304 | 27687385 | 27687507 | In-frame |
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Infer the effects of exon skipping event on protein functional features for PPFIBP1 |
p-ENSG00000110841_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000318304 | 6018 | 1011 | 27647729 | 27647842 | 642 | 754 | 119 | 157 |
| ENST00000318304 | 6018 | 1011 | 27650010 | 27650141 | 756 | 886 | 157 | 201 |
| ENST00000318304 | 6018 | 1011 | 27655143 | 27655235 | 981 | 1072 | 232 | 263 |
| ENST00000318304 | 6018 | 1011 | 27674192 | 27674221 | 1716 | 1744 | 477 | 487 |
| ENST00000318304 | 6018 | 1011 | 27687385 | 27687507 | 2550 | 2671 | 755 | 796 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000318304 | 6018 | 1011 | 27650010 | 27650141 | 756 | 886 | 157 | 201 |
| ENST00000318304 | 6018 | 1011 | 27655143 | 27655235 | 981 | 1072 | 232 | 263 |
| ENST00000318304 | 6018 | 1011 | 27674192 | 27674221 | 1716 | 1744 | 477 | 487 |
| ENST00000318304 | 6018 | 1011 | 27687385 | 27687507 | 2550 | 2671 | 755 | 796 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000318304 | 6018 | 1011 | 27650010 | 27650141 | 756 | 886 | 157 | 201 |
| ENST00000318304 | 6018 | 1011 | 27655143 | 27655235 | 981 | 1072 | 232 | 263 |
| ENST00000318304 | 6018 | 1011 | 27674192 | 27674221 | 1716 | 1744 | 477 | 487 |
| ENST00000318304 | 6018 | 1011 | 27687385 | 27687507 | 2550 | 2671 | 755 | 796 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q86W92 | 119 | 157 | 1 | 153 | Alternative sequence | ID=VSP_009394;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10574462;Dbxref=PMID:10574462 |
| Q86W92 | 119 | 157 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 119 | 157 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 119 | 157 | 148 | 148 | Natural variant | ID=VAR_017758;Note=V->L;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10574462,ECO:0000269|PubMed:15489334,ECO:0000269|PubMed:9624153,ECO:0000269|Ref.4,ECO:0000269|Ref.5;Dbxref=dbSNP:rs2194816,PMID:1 |
| Q86W92 | 157 | 201 | 158 | 170 | Alternative sequence | ID=VSP_009395;Note=In isoform 5. ELLSRTSLETQKL->VCAEARTKMGFPC;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 157 | 201 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 157 | 201 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 157 | 201 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 232 | 263 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 232 | 263 | 233 | 263 | Alternative sequence | ID=VSP_009397;Note=In isoform 2 and isoform 4. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9624153;Dbxref=PMID:15489334,PMID:9624153 |
| Q86W92 | 232 | 263 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 232 | 263 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 477 | 487 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 477 | 487 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 755 | 796 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 755 | 796 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 755 | 796 | 719 | 782 | Domain | Note=SAM 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00184 |
| Q86W92 | 755 | 796 | 794 | 794 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:23186163,PMID:24275569 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q86W92 | 157 | 201 | 158 | 170 | Alternative sequence | ID=VSP_009395;Note=In isoform 5. ELLSRTSLETQKL->VCAEARTKMGFPC;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 157 | 201 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 157 | 201 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 157 | 201 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 232 | 263 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 232 | 263 | 233 | 263 | Alternative sequence | ID=VSP_009397;Note=In isoform 2 and isoform 4. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9624153;Dbxref=PMID:15489334,PMID:9624153 |
| Q86W92 | 232 | 263 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 232 | 263 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 477 | 487 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 477 | 487 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 755 | 796 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 755 | 796 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 755 | 796 | 719 | 782 | Domain | Note=SAM 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00184 |
| Q86W92 | 755 | 796 | 794 | 794 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:23186163,PMID:24275569 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q86W92 | 157 | 201 | 158 | 170 | Alternative sequence | ID=VSP_009395;Note=In isoform 5. ELLSRTSLETQKL->VCAEARTKMGFPC;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 157 | 201 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 157 | 201 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 157 | 201 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 232 | 263 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 232 | 263 | 233 | 263 | Alternative sequence | ID=VSP_009397;Note=In isoform 2 and isoform 4. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9624153;Dbxref=PMID:15489334,PMID:9624153 |
| Q86W92 | 232 | 263 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 232 | 263 | 156 | 405 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q86W92 | 477 | 487 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 477 | 487 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 755 | 796 | 171 | 1011 | Alternative sequence | ID=VSP_009396;Note=In isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|Ref.4,ECO:0000303|Ref.5 |
| Q86W92 | 755 | 796 | 1 | 1011 | Chain | ID=PRO_0000191034;Note=Liprin-beta-1 |
| Q86W92 | 755 | 796 | 719 | 782 | Domain | Note=SAM 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00184 |
| Q86W92 | 755 | 796 | 794 | 794 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:23186163,PMID:24275569 |
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3'-UTR located exon skipping events that lost miRNA binding sites in PPFIBP1 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for PPFIBP1 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for PPFIBP1 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
| ADstage | MSBB | IFG | exon_skip_152069 | 3.808491e-01 | 4.555874e-02 | chr12 | + | 27656616 | 27656730 | 27658816 | 27658848 | 27660884 | 27660945 |
| CDR | MSBB | IFG | exon_skip_152069 | 3.983061e-01 | 3.579002e-02 | chr12 | + | 27656616 | 27656730 | 27658816 | 27658848 | 27660884 | 27660945 |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PPFIBP1 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for PPFIBP1 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| DLPFC | G3BP2 | exon_skip_134421 | 4.558912e-01 | 4.382887e-18 |
| FL | SRSF2 | exon_skip_134421 | 5.430873e-01 | 4.048438e-14 |
| FL | ILF2 | exon_skip_134421 | 6.554655e-01 | 9.515496e-22 |
| FL | HNRNPK | exon_skip_134421 | 5.516401e-01 | 1.332490e-14 |
| FL | G3BP2 | exon_skip_134421 | 7.231860e-01 | 3.723156e-28 |
| FL | RALYL | exon_skip_134421 | 6.019632e-01 | 9.660656e-18 |
| FL | PTBP1 | exon_skip_134421 | -4.976380e-01 | 9.037840e-12 |
| FL | SRSF9 | exon_skip_134421 | 4.528446e-01 | 9.022800e-10 |
| FL | RBM3 | exon_skip_133509 | 4.054013e-01 | 4.960350e-09 |
| HCC | SRSF11 | exon_skip_134421 | -5.015784e-01 | 1.519141e-18 |
| HCC | RBM5 | exon_skip_134421 | -6.151063e-01 | 2.160516e-29 |
| HCC | IGF2BP2 | exon_skip_134421 | -4.589615e-01 | 2.025178e-15 |
| HCC | PTBP1 | exon_skip_134421 | -6.802252e-01 | 6.871329e-38 |
| HCC | SNRNP70 | exon_skip_134421 | -5.729279e-01 | 7.235552e-25 |
| HCC | PABPC1 | exon_skip_134421 | -4.115945e-01 | 2.015325e-12 |
| HCC | HNRNPF | exon_skip_134421 | -6.145803e-01 | 2.484415e-29 |
| HCC | ZC3H10 | exon_skip_134421 | -6.025561e-01 | 5.641387e-28 |
| HCC | RBM3 | exon_skip_133509 | 4.050329e-01 | 4.829141e-12 |
| IFG | KHDRBS3 | exon_skip_152069 | -6.176843e-01 | 4.615286e-04 |
| PCC | SRSF11 | exon_skip_134421 | -4.340164e-01 | 3.393605e-11 |
| PCC | IGF2BP2 | exon_skip_134421 | -4.028772e-01 | 1.021981e-09 |
| PCC | G3BP2 | exon_skip_134421 | 7.141463e-01 | 1.580451e-34 |
| PCC | RALYL | exon_skip_134421 | 4.534079e-01 | 3.393197e-12 |
| PCC | PTBP1 | exon_skip_134421 | -7.582915e-01 | 4.490919e-41 |
| PCC | PABPC1 | exon_skip_134421 | -5.317748e-01 | 6.019638e-17 |
| PCC | HNRNPF | exon_skip_134421 | -6.251327e-01 | 1.710197e-24 |
| PCC | RBM3 | exon_skip_133509 | 5.358875e-01 | 7.371936e-17 |
| PG | RBM47 | exon_skip_134421 | -4.199662e-01 | 1.961263e-08 |
| PG | ILF2 | exon_skip_134421 | 5.181493e-01 | 1.019355e-12 |
| PG | HNRNPK | exon_skip_134421 | 5.182518e-01 | 1.007169e-12 |
| PG | G3BP2 | exon_skip_134421 | 7.217328e-01 | 7.749587e-28 |
| PG | RALYL | exon_skip_134421 | 6.799961e-01 | 9.827531e-24 |
| PG | PTBP1 | exon_skip_134421 | -4.761151e-01 | 1.023126e-10 |
| PG | EWSR1 | exon_skip_134421 | 4.868223e-01 | 3.354633e-11 |
| PG | SART3 | exon_skip_134421 | 4.487855e-01 | 1.488420e-09 |
| PG | HNRNPA0 | exon_skip_229983 | -4.408389e-01 | 6.576658e-10 |
| TC | SRSF2 | exon_skip_134421 | 5.300082e-01 | 1.565542e-12 |
| TC | SRSF11 | exon_skip_134421 | 4.219699e-01 | 5.020597e-08 |
| TC | ILF2 | exon_skip_134421 | 6.015687e-01 | 1.579435e-16 |
| TC | HNRNPK | exon_skip_134421 | 5.174353e-01 | 6.362696e-12 |
| TC | G3BP2 | exon_skip_134421 | 8.081972e-01 | 8.891048e-37 |
| TC | NUP42 | exon_skip_134421 | 7.080123e-01 | 9.874657e-25 |
| TC | RALYL | exon_skip_134421 | 8.705982e-01 | 1.115779e-48 |
| TC | PTBP3 | exon_skip_134421 | 5.778803e-01 | 4.263318e-15 |
| TC | EWSR1 | exon_skip_134421 | 4.240758e-01 | 4.237473e-08 |
| TC | SRSF9 | exon_skip_134421 | 4.683939e-01 | 9.016702e-10 |
| TC | SART3 | exon_skip_134421 | 4.575137e-01 | 2.443054e-09 |
| TC | KHDRBS2 | exon_skip_152069 | -6.758306e-01 | 9.359329e-22 |
| TC | KHDRBS3 | exon_skip_152069 | -6.341426e-01 | 1.376753e-18 |
| TC | NUP42 | exon_skip_152069 | -4.672054e-01 | 1.142660e-09 |
| TC | YBX2 | exon_skip_152069 | -5.319233e-01 | 1.490368e-12 |
| TC | HNRNPA0 | exon_skip_84019 | -4.009660e-01 | 2.803853e-07 |
| TC | NUP42 | exon_skip_84019 | -4.095814e-01 | 1.462782e-07 |
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RelatedDrugs for PPFIBP1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PPFIBP1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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