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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in RPSMAP, MSBB, and Mayo

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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3'-UTR located exon skipping events lost miRNA binding sites

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SNVs in the skipped exons with depth of coverage

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AD stage-associated exon skipping events

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Correlation with RNA binding proteins (RBPs)

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Related drugs with this gene

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Related diseases with this gene

Gene summary for SORBS2

check button Gene summary
Gene informationGene symbol

SORBS2

Gene ID

8470

Gene namesorbin and SH3 domain containing 2
SynonymsARGBP2|PRO0618
Cytomap

4q35.1

Type of geneprotein-coding
Descriptionsorbin and SH3 domain-containing protein 2Arg binding protein 2Arg/Abl-interacting protein 2arg-binding protein 2
Modification date20200313
UniProtAcc

A0A1D5RMN3,

A0A3B3ITL8,

C9IZ89,

C9IZT7,

C9J348,

C9J372,

C9J3W4,

C9J4K2,

C9J4Z9,

C9J620,

C9J7Q5,

C9J8E3,

C9J9D3,

C9JBB0,

C9JBR8,

C9JC90,

C9JDX2,

C9JEA9,

C9JFS9,

C9JG84,

C9JI79,

C9JL62,

C9JLD6,

C9JM25,

C9JN77,

C9JWC3,

C9JZ60,

H7BXR3,

H7BZK1,

H7BZX1,

H7C1R7,

O94875,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Gene structures and expression levels for SORBS2

check buttonSkipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

ENSG00000154556
check button Differentially expressed gene analysis across multiple brain tissues between AD and control.
Tissue typeDEG directionBase mean exp.log2FC(AD/control)P-valueAdj. p-value

check button Differentially expressed isoform analysis across multiple brain tissues between AD and control.
gencode gene structure
Tissue typeDEG directionENSTTranscript info.Base mean exp.log2FC(AD/control)P-valueAdjc. p-value
STGUPENST00000490779.5SORBS2-258:lncRNA:SORBS22.184726e+018.488231e-018.783322e-043.581202e-02
PGDOWNENST00000463104.5SORBS2-242:lncRNA:SORBS25.731828e+00-1.085703e+004.851894e-034.473333e-02
PGUPENST00000438278.5SORBS2-222:protein_coding:SORBS22.731592e+002.480436e+004.893854e-034.500807e-02
CBDOWNENST00000650145.1SORBS2-265:protein_coding:SORBS22.817867e+02-1.240979e+003.636232e-101.892149e-08
CBUPENST00000449407.6SORBS2-231:protein_coding:SORBS22.723995e+011.184888e+001.954468e-051.855589e-04
CBUPENST00000495932.5SORBS2-263:lncRNA:SORBS21.854287e+008.071980e-013.727067e-042.249412e-03
TCUPENST00000490779.5SORBS2-258:lncRNA:SORBS21.708665e+018.704676e-017.046378e-096.726382e-07
TCUPENST00000444771.5SORBS2-225:protein_coding:SORBS27.403209e+009.111739e-011.202979e-041.874031e-03
TCUPENST00000490562.5SORBS2-257:lncRNA:SORBS21.824109e+001.672458e+008.089111e-048.382596e-03
TCUPENST00000425679.5SORBS2-214:protein_coding:SORBS23.787066e+001.172222e+009.314706e-049.363444e-03
TCUPENST00000430503.5SORBS2-217:protein_coding:SORBS27.475660e-011.343049e+002.527323e-032.004431e-02

check button Landscape of isoform expressions across multiple brain tissues between AD and control.
gencode gene structure

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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for SORBS2

check button Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap).
boxplot

check button All exon skipping events in AD cohorts.
Exon skip IDchrExons involved in exon skippingSkipped exon
exon_skip_101114chr4185635355:185635411:185638079:185638162:185646668:185646782185638079:185638162
exon_skip_137348chr4185775281:185775366:185894297:185894373:185956196:185956652185894297:185894373
exon_skip_150164chr4185775281:185775366:185894297:185894373:185956196:185956334185894297:185894373
exon_skip_150573chr4185678796:185678822:185684754:185684846:185775227:185775366185684754:185684846
exon_skip_182020chr4185620063:185620151:185622914:185624494:185626832:185626909185622914:185624494
exon_skip_18534chr4185649467:185649656:185652662:185652728:185657424:185657520185652662:185652728
exon_skip_185809chr4185678796:185678822:185690562:185690611:185734099:185734154185690562:185690611
exon_skip_187703chr4185678796:185678822:185684754:185684846:185690562:185690599185684754:185684846
exon_skip_195230chr4185589679:185589785:185593886:185593935:185611780:185611980185593886:185593935
exon_skip_19966chr4185678796:185678822:185690562:185690611:185775227:185775366185690562:185690611
exon_skip_207227chr4185635355:185635411:185638877:185639035:185646668:185646782185638877:185639035
exon_skip_214122chr4185678796:185678822:185775227:185775366:185811664:185811752185775227:185775366
exon_skip_217611chr4185684754:185684846:185690562:185690611:185775231:185775366185690562:185690611
exon_skip_218993chr4185662104:185662242:185676997:185677638:185678423:185678478185676997:185677638
exon_skip_22163chr4185678796:185678822:185684754:185684842:185690562:185690611185684754:185684842
exon_skip_233381chr4185630549:185630598:185635355:185635411:185638877:185639035185635355:185635411
exon_skip_234112chr4185678796:185678822:185775060:185775111:185775227:185775366185775060:185775111
exon_skip_257967chr4185649467:185649656:185651784:185651828:185652662:185652688185651784:185651828
exon_skip_273395chr4185775281:185775366:185894297:185894373:185932936:185933370185894297:185894373
exon_skip_278907chr4185684754:185684846:185690562:185690611:185734099:185734154185690562:185690611
exon_skip_292929chr4185630549:185630598:185635355:185635411:185646668:185646782185635355:185635411
exon_skip_295455chr4185690562:185690611:185734099:185734154:185775227:185775366185734099:185734154
exon_skip_33136chr4185630549:185630598:185635355:185635411:185638079:185638162185635355:185635411
exon_skip_4854chr4185618602:185618631:185620063:185620151:185626832:185626909185620063:185620151
exon_skip_48775chr4185684754:185684846:185734099:185734154:185775227:185775366185734099:185734154
exon_skip_60974chr4185678796:185678822:185684754:185684846:185734099:185734154185684754:185684846
exon_skip_65220chr4185678796:185678822:185684754:185684842:185690562:185690599185684754:185684842
exon_skip_70585chr4185678796:185678822:185734099:185734154:185775227:185775366185734099:185734154
exon_skip_80024chr4185684754:185684846:185690562:185690611:185775227:185775366185690562:185690611
exon_skip_94097chr4185662235:185662242:185676997:185677638:185678423:185678478185676997:185677638

check button Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control.
psi tcga
Exon skipping informationTissue typeAvg(PSIs) in ADAvg(PSIs) in controlDifference (PSI)Adj. p-value
exon_skip_257967Mayo_CB6.324359e-017.479310e-01-1.154951e-012.108715e-06


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Open reading frame (ORF) annotation in the exon skipping event for SORBS2

check button Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000284776185593886185593935Frame-shift
ENST00000284776185622914185624494In-frame
ENST00000284776185651784185651828In-frame

check button Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000284776185593886185593935Frame-shift
ENST00000284776185622914185624494In-frame
ENST00000284776185651784185651828In-frame

check button Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000284776185593886185593935Frame-shift
ENST00000284776185622914185624494In-frame
ENST00000284776185651784185651828In-frame

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Infer the effects of exon skipping event on protein functional features for SORBS2

p-ENSG00000154556_img4.png
boxplot

check button Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000028477660131100185651784185651828845888111126
ENST000002847766013110018562291418562449414333012307834

check button Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000028477660131100185651784185651828845888111126
ENST000002847766013110018562291418562449414333012307834

check button Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000028477660131100185651784185651828845888111126
ENST000002847766013110018562291418562449414333012307834

check button Lost protein functional features of individual exon skipping events in ROSMAP.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O94875111126112126Alternative sequenceID=VSP_043666;Note=In isoform 7 and isoform 9. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|Ref.5;Dbxref=PMID:14702039
O9487511112611100ChainID=PRO_0000344477;Note=Sorbin and SH3 domain-containing protein 2
O9487511112666127DomainNote=SoHo;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00195
O948753078342381100Alternative sequenceID=VSP_034797;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:11786189;Dbxref=PMID:11786189
O94875307834308834Alternative sequenceID=VSP_034798;Note=In isoform 2%2C isoform 3%2C isoform 4%2C isoform 5%2C isoform 8%2C isoform 9%2C isoform 10 and isoform 12. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15
O9487530783411100ChainID=PRO_0000344477;Note=Sorbin and SH3 domain-containing protein 2
O94875307834640652Compositional biasNote=His-rich
O94875307834383383Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834494494Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O35413
O94875307834497497Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834550550Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834750750Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834536536Sequence conflictNote=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305

check button Lost protein functional features of individual exon skipping events in MSBB.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O94875111126112126Alternative sequenceID=VSP_043666;Note=In isoform 7 and isoform 9. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|Ref.5;Dbxref=PMID:14702039
O9487511112611100ChainID=PRO_0000344477;Note=Sorbin and SH3 domain-containing protein 2
O9487511112666127DomainNote=SoHo;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00195
O948753078342381100Alternative sequenceID=VSP_034797;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:11786189;Dbxref=PMID:11786189
O94875307834308834Alternative sequenceID=VSP_034798;Note=In isoform 2%2C isoform 3%2C isoform 4%2C isoform 5%2C isoform 8%2C isoform 9%2C isoform 10 and isoform 12. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15
O9487530783411100ChainID=PRO_0000344477;Note=Sorbin and SH3 domain-containing protein 2
O94875307834640652Compositional biasNote=His-rich
O94875307834383383Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834494494Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O35413
O94875307834497497Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834550550Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834750750Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834536536Sequence conflictNote=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305

check button Lost protein functional features of individual exon skipping events in Mayo.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O94875111126112126Alternative sequenceID=VSP_043666;Note=In isoform 7 and isoform 9. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|Ref.5;Dbxref=PMID:14702039
O9487511112611100ChainID=PRO_0000344477;Note=Sorbin and SH3 domain-containing protein 2
O9487511112666127DomainNote=SoHo;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00195
O948753078342381100Alternative sequenceID=VSP_034797;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:11786189;Dbxref=PMID:11786189
O94875307834308834Alternative sequenceID=VSP_034798;Note=In isoform 2%2C isoform 3%2C isoform 4%2C isoform 5%2C isoform 8%2C isoform 9%2C isoform 10 and isoform 12. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15
O9487530783411100ChainID=PRO_0000344477;Note=Sorbin and SH3 domain-containing protein 2
O94875307834640652Compositional biasNote=His-rich
O94875307834383383Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834494494Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:O35413
O94875307834497497Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834550550Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834750750Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q3UTJ2
O94875307834536536Sequence conflictNote=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305


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3'-UTR located exon skipping events that lost miRNA binding sites in SORBS2

check button 3'-UTR exon skipping evnets lost miRNA binding.
Tissue typeENSTExon skip startExon skip endmicroRNABinding site by TargetScanBinding type by TargetScanBdinding site by miRandaScore of miRandaEnergy by miRanda

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SNVs in the skipped exons for SORBS2

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Depth of Coverage in the skipped exon of the mutated samples.

check button - Sashimi plot in the skipped exon of the mutated samples.

check button - Non-synonymous mutations located in the skipped exons.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

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AD stage-associated exon skippint events for SORBS2

check button Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR).
AD stage infoCohortTissueSE idCoefficient P-valueChromosomeStrandE1 startE1 endSkipped startSkipped endE2 startE2 end

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for SORBS2

check button sQTL information located at the skipped exons.
Tissue typeExon skip IDSNP idLocationP-valueFDR
HCCexon_skip_150573rs12512174chr4:1856915783.705231e-042.675241e-02
PCCexon_skip_80024rs13147441chr4:1857171142.907447e-068.746421e-04

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Correlation with RNA binding proteins (RBPs) for SORBS2

check button Correlated RBP and related information.
Tissue typeRBP nameExon skip IDCorrelation coeifficientP-value
CBTARDBPexon_skip_195230-4.149567e-011.064644e-07
CBCNOT4exon_skip_195230-4.232350e-015.559230e-08
CBFUBP1exon_skip_195230-5.463136e-013.336193e-13
CBELAVL1exon_skip_1820204.393163e-013.239673e-08
CBFXR2exon_skip_1820204.185642e-011.613290e-07
CBHNRNPKexon_skip_1820204.371515e-013.849738e-08
CBPCBP2exon_skip_1820204.316860e-015.919741e-08
CBSF1exon_skip_1820204.524192e-011.110818e-08
CBHNRNPA0exon_skip_1820204.723789e-011.989692e-09
CBPUM1exon_skip_1820204.365147e-014.049241e-08
CBHNRNPLexon_skip_1820204.078075e-013.557037e-07
CBCELF1exon_skip_1820204.064084e-013.934384e-07
CBEIF4Bexon_skip_1820204.006900e-015.912601e-07
CBDAZAP1exon_skip_257967-5.012844e-015.100465e-10
CBCNOT4exon_skip_257967-5.001999e-015.632248e-10
CBFUBP1exon_skip_257967-4.496796e-013.975027e-08
CBPABPN1exon_skip_150573-4.057108e-019.085304e-06
CBTRA2Aexon_skip_150573-4.171569e-014.747741e-06
CBSRSF4exon_skip_150573-4.511178e-015.982903e-07
FLSRSF2exon_skip_1820204.301360e-015.327961e-09
FLHNRNPKexon_skip_1820204.037865e-015.213690e-08
FLKHDRBS3exon_skip_1820204.883132e-011.641363e-11
FLRBM24exon_skip_1820204.728486e-018.501637e-11
FLHNRNPA0exon_skip_1820204.513897e-017.300661e-10
FLPUM1exon_skip_1820204.803504e-013.867781e-11
FLRALYLexon_skip_1820205.073521e-011.928570e-12
FLHNRNPLexon_skip_1820204.125829e-012.488202e-08
FLCELF1exon_skip_1820204.279890e-016.463898e-09
FLNOVA1exon_skip_1820205.261020e-012.047851e-13
HCCTARDBPexon_skip_182020-4.220658e-016.478333e-13
HCCMSI1exon_skip_182020-6.581650e-012.113154e-34
HCCZNF326exon_skip_182020-6.248444e-013.277215e-30
HCCSFPQexon_skip_182020-5.820434e-011.617279e-25
HCCRBM6exon_skip_182020-6.483044e-014.165789e-33
HCCSRSF11exon_skip_182020-5.678585e-014.132891e-24
HCCSAMD4Aexon_skip_182020-5.710321e-012.028879e-24
HCCCNOT4exon_skip_182020-4.382071e-016.590506e-14
HCCRBM5exon_skip_182020-6.207353e-019.946070e-30
HCCIGF2BP2exon_skip_182020-4.648405e-011.152926e-15
HCCPCBP1exon_skip_182020-4.261298e-013.685651e-13
HCCPCBP4exon_skip_182020-5.259347e-012.529351e-20
HCCUNKexon_skip_182020-5.951847e-016.951982e-27
HCCTRA2Aexon_skip_182020-4.254581e-014.047875e-13
HCCPCBP2exon_skip_182020-4.372755e-017.544807e-14
HCCSF1exon_skip_182020-5.114615e-013.912695e-19
HCCKHDRBS3exon_skip_182020-5.377586e-012.444211e-21
HCCFUBP1exon_skip_182020-4.696898e-015.309754e-16
HCCRBM45exon_skip_182020-5.724968e-011.457181e-24
HCCEIF4G2exon_skip_182020-5.573815e-014.102667e-23
HCCPTBP1exon_skip_182020-7.054180e-012.385299e-41
HCCSNRNP70exon_skip_182020-6.019204e-011.309150e-27
HCCPABPC5exon_skip_182020-4.984011e-014.152548e-18
HCCPABPC1exon_skip_182020-4.898734e-011.840019e-17
HCCPABPC4exon_skip_182020-4.549785e-015.374723e-15
HCCSRSF1exon_skip_182020-4.285378e-012.629170e-13
HCCSRSF5exon_skip_182020-4.859568e-013.595565e-17
HCCRBM41exon_skip_182020-5.215291e-015.903463e-20
HCCHNRNPFexon_skip_182020-6.391696e-015.986173e-32
HCCRBM4exon_skip_182020-4.843810e-014.696479e-17
HCCZC3H10exon_skip_182020-6.489306e-013.458602e-33
HCCRBM4Bexon_skip_182020-5.961417e-015.497052e-27
HCCDAZAP1exon_skip_257967-4.162781e-011.295862e-12
HCCRBMS2exon_skip_257967-4.635965e-011.241600e-15
HCCMSI1exon_skip_150573-4.356794e-011.806900e-13
HCCPABPN1exon_skip_150573-4.194946e-011.666257e-12
HCCSRSF4exon_skip_150573-4.205092e-011.454671e-12
HCCDAZAP1exon_skip_199664.022695e-011.088552e-11
HCCRBM5exon_skip_199664.137521e-012.429703e-12
HCCUNKexon_skip_199664.188531e-011.225056e-12
IFGPABPC3exon_skip_182020-4.079640e-013.115557e-02
IFGESRP2exon_skip_182020-4.334158e-012.122056e-02
IFGTARDBPexon_skip_150573-4.475979e-012.185560e-02
IFGCNOT4exon_skip_150573-4.104669e-013.726560e-02
IFGHNRNPABexon_skip_150573-4.129319e-013.602933e-02
IFGSRSF4exon_skip_150573-4.504874e-012.091683e-02
IFGHNRNPFexon_skip_150573-4.352881e-012.624673e-02
PCCMSI1exon_skip_182020-4.918813e-015.206197e-14
PCCZNF326exon_skip_182020-5.754005e-011.207516e-19
PCCSFPQexon_skip_182020-4.580065e-013.952063e-12
PCCRBM6exon_skip_182020-5.280863e-012.908257e-16
PCCSRSF11exon_skip_182020-5.351983e-019.743968e-17
PCCSAMD4Aexon_skip_182020-4.635497e-012.009646e-12
PCCIGF2BP2exon_skip_182020-4.469833e-011.463491e-11
PCCPCBP4exon_skip_182020-6.006508e-011.102391e-21
PCCTRA2Aexon_skip_182020-4.274056e-011.337206e-10
PCCRBM45exon_skip_182020-4.422247e-012.538628e-11
PCCPTBP1exon_skip_182020-6.662665e-016.260080e-28
PCCPABPC1exon_skip_182020-5.838621e-012.618805e-20
PCCPABPC4exon_skip_182020-4.644628e-011.795676e-12
PCCHNRNPFexon_skip_182020-6.047666e-014.927163e-22
PCCZC3H10exon_skip_182020-4.538314e-016.524877e-12
PCCRBM4Bexon_skip_182020-4.372693e-014.464708e-11
PCCHNRNPFexon_skip_187703-4.603023e-011.486998e-09
PGSAMD4Aexon_skip_182020-4.035192e-019.243025e-08
PGFXR2exon_skip_1820204.318679e-018.608376e-09
PGPCBP1exon_skip_1820204.394207e-014.404152e-09
PGKHDRBS2exon_skip_1820204.306785e-019.552348e-09
PGKHDRBS3exon_skip_1820204.590382e-017.141874e-10
PGRBM24exon_skip_1820204.032711e-019.428013e-08
PGPUM1exon_skip_1820204.054615e-017.910162e-08
PGRALYLexon_skip_1820204.981562e-011.320905e-11
PGHNRNPH2exon_skip_1820204.768689e-011.233109e-10
STGSRSF2exon_skip_1820204.248358e-012.466537e-04
STGELAVL1exon_skip_1820204.303938e-012.000946e-04
STGSRSF11exon_skip_1820204.758192e-013.140504e-05
STGCNOT4exon_skip_1820204.094313e-014.323695e-04
STGFXR2exon_skip_1820204.144598e-013.610432e-04
STGPCBP1exon_skip_1820204.511527e-018.866092e-05
STGILF2exon_skip_1820204.563180e-017.180935e-05
STGHNRNPKexon_skip_1820204.317871e-011.897645e-04
STGKHDRBS2exon_skip_1820205.222638e-013.531967e-06
STGKHDRBS3exon_skip_1820205.295958e-012.427007e-06
STGRBM24exon_skip_1820205.050826e-018.228512e-06
STGFUBP1exon_skip_1820204.008774e-015.837977e-04
STGENOX1exon_skip_1820204.375105e-011.522642e-04
STGHNRNPA0exon_skip_1820205.715663e-012.368077e-07
STGPUM1exon_skip_1820204.552054e-017.516678e-05
STGHNRNPDLexon_skip_1820204.456197e-011.107103e-04
STGNUP42exon_skip_1820205.413447e-011.305753e-06
STGRALYLexon_skip_1820206.198578e-011.053739e-08
STGEIF4G2exon_skip_1820204.527978e-018.293421e-05
STGHNRNPLexon_skip_1820204.299135e-012.037737e-04
STGCELF1exon_skip_1820204.640923e-015.195092e-05
STGPABPC4exon_skip_1820204.317771e-011.898366e-04
STGSRSF1exon_skip_1820204.003521e-015.945084e-04
STGSRSF9exon_skip_1820204.354329e-011.650074e-04
STGHNRNPH2exon_skip_1820204.624639e-015.563169e-05
STGSART3exon_skip_1820204.532220e-018.151397e-05
STGNOVA1exon_skip_1820205.225919e-013.473807e-06
TCSRSF2exon_skip_1820205.711054e-011.903551e-14
TCMSI1exon_skip_182020-4.297656e-013.653487e-08
TCRBM3exon_skip_1820204.357784e-012.237964e-08
TCMBNL1exon_skip_1820204.210087e-017.334775e-08
TCFXR2exon_skip_1820204.995499e-016.595491e-11
TCILF2exon_skip_1820205.431282e-015.803921e-13
TCHNRNPKexon_skip_1820204.346241e-012.460574e-08
TCKHDRBS2exon_skip_1820208.644033e-012.425058e-46
TCKHDRBS3exon_skip_1820207.328795e-011.059428e-26
TCRBM24exon_skip_1820207.382915e-012.887948e-27
TCENOX1exon_skip_1820204.531607e-015.137853e-09
TCHNRNPA0exon_skip_1820207.219073e-011.343965e-25
TCPUM1exon_skip_1820206.754849e-011.849728e-21
TCPPRC1exon_skip_1820204.137033e-011.292410e-07
TCHNRNPDLexon_skip_1820204.909774e-011.550352e-10
TCRBM45exon_skip_1820204.818849e-013.741679e-10
TCNUP42exon_skip_1820206.734975e-012.676051e-21
TCRALYLexon_skip_1820208.246090e-011.078276e-38
TCPTBP1exon_skip_182020-4.956815e-019.727879e-11
TCPTBP3exon_skip_1820205.010925e-015.640944e-11
TCHNRNPLexon_skip_1820204.117302e-011.502627e-07
TCCELF1exon_skip_1820205.989528e-014.529474e-16
TCEWSR1exon_skip_1820204.358678e-012.221557e-08
TCFUSexon_skip_1820204.592848e-012.998885e-09
TCSRSF9exon_skip_1820204.005866e-013.456992e-07
TCSRSF5exon_skip_1820204.280750e-014.186115e-08
TCHNRNPH2exon_skip_1820207.451525e-015.303621e-28
TCESRP1exon_skip_1820205.895303e-011.670466e-15
TCNOVA1exon_skip_1820206.924291e-017.032734e-23
TCRBMS2exon_skip_257967-4.035664e-014.010300e-07
TCHNRNPDLexon_skip_2579674.497824e-011.095830e-08
TCHNRNPDexon_skip_2579674.820052e-016.358858e-10
TCNOVA1exon_skip_2579675.278402e-016.423382e-12
TCILF2exon_skip_1505734.075838e-018.183180e-06
TCRBM24exon_skip_1505735.217739e-013.647907e-09
TCHNRNPH2exon_skip_1505735.878656e-019.458256e-12
TCESRP1exon_skip_1505734.177662e-014.583433e-06
TCKHDRBS3exon_skip_19966-5.191876e-012.004644e-09
TCENOX1exon_skip_19966-4.641482e-011.357017e-07
TCHNRNPDexon_skip_19966-4.416054e-016.226189e-07
TCESRP1exon_skip_19966-4.427831e-015.765293e-07
TCNOVA1exon_skip_19966-5.080449e-015.002521e-09

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RelatedDrugs for SORBS2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SORBS2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource