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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for TSGA10 |
 Gene summary |
| Gene information | Gene symbol | TSGA10 | Gene ID | 80705 |
| Gene name | testis specific 10 | |
| Synonyms | CEP4L|CT79|SPGF26 | |
| Cytomap | 2q11.2 | |
| Type of gene | protein-coding | |
| Description | testis-specific gene 10 proteincancer/testis antigen 79testis development protein NYD-SP7testis-specific 10 protein | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for TSGA10 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000135951
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | DOWN | ENST00000483914.5 | TSGA10-212:lncRNA:TSGA10 | 7.499456e-01 | -1.187565e+00 | 4.495354e-04 | 2.632609e-03 |
| TC | DOWN | ENST00000489546.5 | TSGA10-215:lncRNA:TSGA10 | 1.258892e+01 | -9.138611e-01 | 1.535916e-05 | 3.649585e-04 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for TSGA10 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_112115 | chr2 | 99105527:99105697:99108833:99108991:99109389:99109512 | 99108833:99108991 |
| exon_skip_121582 | chr2 | 99117688:99117759:99118551:99118686:99127048:99127146 | 99118551:99118686 |
| exon_skip_122739 | chr2 | 99117567:99117759:99127048:99127176:99141068:99141149 | 99127048:99127176 |
| exon_skip_124054 | chr2 | 99118551:99118686:99118777:99118801:99127048:99127176 | 99118777:99118801 |
| exon_skip_137531 | chr2 | 99071706:99071874:99073018:99073073:99078659:99078813 | 99073018:99073073 |
| exon_skip_140215 | chr2 | 99018536:99018640:99020280:99020482:99035230:99035439 | 99020280:99020482 |
| exon_skip_146079 | chr2 | 99073018:99073073:99078659:99078813:99081282:99081397 | 99078659:99078813 |
| exon_skip_147851 | chr2 | 99117688:99117759:99127048:99127176:99154693:99154861 | 99127048:99127176 |
| exon_skip_15408 | chr2 | 99117567:99117759:99118551:99118686:99127048:99127176 | 99118551:99118686 |
| exon_skip_159096 | chr2 | 99018536:99018640:99020280:99020482:99064939:99065124 | 99020280:99020482 |
| exon_skip_1851 | chr2 | 98997886:98998221:99018200:99018349:99018536:99018640 | 99018200:99018349 |
| exon_skip_196862 | chr2 | 99018536:99018640:99020280:99020482:99035230:99035426 | 99020280:99020482 |
| exon_skip_198462 | chr2 | 99078659:99078813:99081282:99081397:99103967:99104118 | 99081282:99081397 |
| exon_skip_199612 | chr2 | 99117567:99117759:99127048:99127176:99141428:99141572 | 99127048:99127176 |
| exon_skip_21915 | chr2 | 99117567:99117759:99127048:99127176:99141083:99141149 | 99127048:99127176 |
| exon_skip_222944 | chr2 | 99148264:99148348:99154291:99154427:99154693:99154890 | 99154291:99154427 |
| exon_skip_249349 | chr2 | 99073018:99073073:99081282:99081397:99103967:99104118 | 99081282:99081397 |
| exon_skip_249785 | chr2 | 99018536:99018640:99035230:99035439:99064939:99065124 | 99035230:99035439 |
| exon_skip_272502 | chr2 | 99110850:99110915:99117544:99117759:99127048:99127176 | 99117544:99117759 |
| exon_skip_35587 | chr2 | 99148265:99148348:99154291:99154427:99154693:99154861 | 99154291:99154427 |
| exon_skip_41807 | chr2 | 99117544:99117759:99127048:99127176:99154693:99154962 | 99127048:99127176 |
| exon_skip_54240 | chr2 | 99117567:99117759:99118551:99118686:99127048:99127146 | 99118551:99118686 |
| exon_skip_61908 | chr2 | 99110850:99110915:99117544:99117759:99127048:99127146 | 99117544:99117759 |
| exon_skip_72934 | chr2 | 99110850:99110915:99117544:99117759:99154693:99154861 | 99117544:99117759 |
| exon_skip_7365 | chr2 | 99118551:99118686:99118777:99118801:99127048:99127146 | 99118777:99118801 |
| exon_skip_77511 | chr2 | 99071706:99071874:99073018:99073073:99078659:99078928 | 99073018:99073073 |
| exon_skip_79166 | chr2 | 99103967:99104118:99105359:99105436:99105527:99105697 | 99105359:99105436 |
| exon_skip_82045 | chr2 | 99117567:99117759:99127048:99127176:99154693:99154861 | 99127048:99127176 |
| exon_skip_82704 | chr2 | 99117567:99117759:99118551:99118686:99118777:99118801 | 99118551:99118686 |
| exon_skip_9364 | chr2 | 99020280:99020482:99035230:99035439:99064939:99065124 | 99035230:99035439 |
| exon_skip_9940 | chr2 | 99148265:99148348:99154291:99154427:99154837:99154869 | 99154291:99154427 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for TSGA10 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000355053 | 99117544 | 99117759 | 3UTR-3UTR |
| ENST00000393483 | 99118551 | 99118686 | 3UTR-3UTR |
| ENST00000355053 | 99127048 | 99127176 | 3UTR-3UTR |
| ENST00000355053 | 99020280 | 99020482 | Frame-shift |
| ENST00000393483 | 99020280 | 99020482 | Frame-shift |
| ENST00000410001 | 99020280 | 99020482 | Frame-shift |
| ENST00000355053 | 99073018 | 99073073 | Frame-shift |
| ENST00000393483 | 99073018 | 99073073 | Frame-shift |
| ENST00000410001 | 99073018 | 99073073 | Frame-shift |
| ENST00000355053 | 99078659 | 99078813 | Frame-shift |
| ENST00000393483 | 99078659 | 99078813 | Frame-shift |
| ENST00000410001 | 99078659 | 99078813 | Frame-shift |
| ENST00000355053 | 99108833 | 99108991 | In-frame |
| ENST00000393483 | 99108833 | 99108991 | In-frame |
| ENST00000410001 | 99108833 | 99108991 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000355053 | 99117544 | 99117759 | 3UTR-3UTR |
| ENST00000393483 | 99118551 | 99118686 | 3UTR-3UTR |
| ENST00000355053 | 99127048 | 99127176 | 3UTR-3UTR |
| ENST00000355053 | 99020280 | 99020482 | Frame-shift |
| ENST00000393483 | 99020280 | 99020482 | Frame-shift |
| ENST00000410001 | 99020280 | 99020482 | Frame-shift |
| ENST00000355053 | 99073018 | 99073073 | Frame-shift |
| ENST00000393483 | 99073018 | 99073073 | Frame-shift |
| ENST00000410001 | 99073018 | 99073073 | Frame-shift |
| ENST00000355053 | 99078659 | 99078813 | Frame-shift |
| ENST00000393483 | 99078659 | 99078813 | Frame-shift |
| ENST00000410001 | 99078659 | 99078813 | Frame-shift |
| ENST00000355053 | 99035230 | 99035439 | In-frame |
| ENST00000393483 | 99035230 | 99035439 | In-frame |
| ENST00000410001 | 99035230 | 99035439 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000355053 | 99117544 | 99117759 | 3UTR-3UTR |
| ENST00000393483 | 99118551 | 99118686 | 3UTR-3UTR |
| ENST00000355053 | 99127048 | 99127176 | 3UTR-3UTR |
| ENST00000355053 | 99020280 | 99020482 | Frame-shift |
| ENST00000393483 | 99020280 | 99020482 | Frame-shift |
| ENST00000410001 | 99020280 | 99020482 | Frame-shift |
| ENST00000355053 | 99073018 | 99073073 | Frame-shift |
| ENST00000393483 | 99073018 | 99073073 | Frame-shift |
| ENST00000410001 | 99073018 | 99073073 | Frame-shift |
| ENST00000355053 | 99081282 | 99081397 | Frame-shift |
| ENST00000393483 | 99081282 | 99081397 | Frame-shift |
| ENST00000410001 | 99081282 | 99081397 | Frame-shift |
| ENST00000355053 | 99018200 | 99018349 | In-frame |
| ENST00000393483 | 99018200 | 99018349 | In-frame |
| ENST00000410001 | 99018200 | 99018349 | In-frame |
| ENST00000355053 | 99035230 | 99035439 | In-frame |
| ENST00000393483 | 99035230 | 99035439 | In-frame |
| ENST00000410001 | 99035230 | 99035439 | In-frame |
| ENST00000355053 | 99105359 | 99105436 | In-frame |
| ENST00000393483 | 99105359 | 99105436 | In-frame |
| ENST00000410001 | 99105359 | 99105436 | In-frame |
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Infer the effects of exon skipping event on protein functional features for TSGA10 |
p-ENSG00000135951_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000355053 | 3054 | 698 | 99108833 | 99108991 | 681 | 838 | 17 | 69 |
| ENST00000393483 | 3895 | 698 | 99108833 | 99108991 | 897 | 1054 | 17 | 69 |
| ENST00000410001 | 3053 | 698 | 99108833 | 99108991 | 680 | 837 | 17 | 69 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000355053 | 3054 | 698 | 99035230 | 99035439 | 2034 | 2242 | 468 | 537 |
| ENST00000393483 | 3895 | 698 | 99035230 | 99035439 | 2250 | 2458 | 468 | 537 |
| ENST00000410001 | 3053 | 698 | 99035230 | 99035439 | 2033 | 2241 | 468 | 537 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000355053 | 3054 | 698 | 99105359 | 99105436 | 1011 | 1087 | 127 | 152 |
| ENST00000393483 | 3895 | 698 | 99105359 | 99105436 | 1227 | 1303 | 127 | 152 |
| ENST00000410001 | 3053 | 698 | 99105359 | 99105436 | 1010 | 1086 | 127 | 152 |
| ENST00000355053 | 3054 | 698 | 99035230 | 99035439 | 2034 | 2242 | 468 | 537 |
| ENST00000393483 | 3895 | 698 | 99035230 | 99035439 | 2250 | 2458 | 468 | 537 |
| ENST00000410001 | 3053 | 698 | 99035230 | 99035439 | 2033 | 2241 | 468 | 537 |
| ENST00000355053 | 3054 | 698 | 99018200 | 99018349 | 2552 | 2700 | 641 | 690 |
| ENST00000393483 | 3895 | 698 | 99018200 | 99018349 | 2768 | 2916 | 641 | 690 |
| ENST00000410001 | 3053 | 698 | 99018200 | 99018349 | 2551 | 2699 | 641 | 690 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9BZW7 | 17 | 69 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 17 | 69 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 17 | 69 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 17 | 69 | 28 | 28 | Sequence conflict | Note=T->EP;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9BZW7 | 17 | 69 | 28 | 28 | Sequence conflict | Note=T->EP;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Q9BZW7 | 17 | 69 | 28 | 28 | Sequence conflict | Note=T->EP;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9BZW7 | 468 | 537 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 468 | 537 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 468 | 537 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 468 | 537 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 468 | 537 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 468 | 537 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9BZW7 | 127 | 152 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 127 | 152 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 127 | 152 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 468 | 537 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 468 | 537 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 468 | 537 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 468 | 537 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 468 | 537 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 468 | 537 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 641 | 690 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 641 | 690 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 641 | 690 | 298 | 698 | Alternative sequence | ID=VSP_054410;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| Q9BZW7 | 641 | 690 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 641 | 690 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 641 | 690 | 1 | 698 | Chain | ID=PRO_0000307125;Note=Testis-specific gene 10 protein |
| Q9BZW7 | 641 | 690 | 688 | 688 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9Z220 |
| Q9BZW7 | 641 | 690 | 688 | 688 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9Z220 |
| Q9BZW7 | 641 | 690 | 688 | 688 | Modified residue | Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9Z220 |
| Q9BZW7 | 641 | 690 | 556 | 689 | Region | Note=Interaction with HIF1A;Ontology_term=ECO:0000250;evidence=ECO:0000250 |
| Q9BZW7 | 641 | 690 | 556 | 689 | Region | Note=Interaction with HIF1A;Ontology_term=ECO:0000250;evidence=ECO:0000250 |
| Q9BZW7 | 641 | 690 | 556 | 689 | Region | Note=Interaction with HIF1A;Ontology_term=ECO:0000250;evidence=ECO:0000250 |
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3'-UTR located exon skipping events that lost miRNA binding sites in TSGA10 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-5697 | chr2:99117672-99117679 | 8mer-1a | chr2:99117655-99117680 | 157.00 | -19.58 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-6084 | chr2:99117567-99117574 | 8mer-1a | chr2:99117555-99117574 | 149.00 | -20.01 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-186-5p | chr2:99117633-99117640 | 8mer-1a | chr2:99117624-99117640 | 151.00 | -8.93 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4691-5p | chr2:99118597-99118604 | 8mer-1a | chr2:99118595-99118618 | 159.00 | -17.50 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-3165 | chr2:99117574-99117581 | 8mer-1a | chr2:99117560-99117581 | 142.00 | -13.39 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4492 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-4496 | chr2:99117708-99117715 | 8mer-1a | chr2:99117703-99117726 | 157.00 | -18.93 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4498 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-3173-3p | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| Mayo | ENST00000355053 | 99127048 | 99127176 | hsa-miR-6085 | chr2:99127141-99127148 | 8mer-1a | chr2:99127124-99127148 | 164.00 | -22.74 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-762 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-6782-3p | chr2:99118670-99118677 | 8mer-1a | chr2:99118655-99118677 | 150.00 | -14.38 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4747-5p | chr2:99118614-99118621 | 8mer-1a | chr2:99118602-99118623 | 171.00 | -26.17 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-6792-3p | chr2:99118597-99118604 | 8mer-1a | chr2:99118595-99118618 | 159.00 | -17.50 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-5196-5p | chr2:99118614-99118621 | 8mer-1a | chr2:99118602-99118623 | 171.00 | -26.17 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-371a-5p | chr2:99117744-99117751 | 8mer-1a | chr2:99117735-99117756 | 156.00 | -13.06 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-1258 | chr2:99117711-99117718 | 8mer-1a | chr2:99117703-99117726 | 157.00 | -18.93 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-5001-5p | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4326 | chr2:99118599-99118606 | 8mer-1a | chr2:99118598-99118621 | 166.00 | -23.80 |
| Mayo | ENST00000355053 | 99127048 | 99127176 | hsa-miR-6813-5p | chr2:99127141-99127148 | 8mer-1a | chr2:99127124-99127148 | 164.00 | -22.74 |
| Mayo | ENST00000393483 | 99118551 | 99118686 | hsa-miR-8069 | chr2:99118633-99118640 | 8mer-1a | chr2:99118617-99118640 | 151.00 | -20.63 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-12118 | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| Mayo | ENST00000355053 | 99117544 | 99117759 | hsa-miR-6891-5p | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| Mayo | ENST00000355053 | 99127048 | 99127176 | hsa-miR-601 | chr2:99127146-99127153 | 8mer-1a | chr2:99127132-99127153 | 145.00 | -19.81 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-5697 | chr2:99117672-99117679 | 8mer-1a | chr2:99117655-99117680 | 157.00 | -19.58 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-6084 | chr2:99117567-99117574 | 8mer-1a | chr2:99117555-99117574 | 149.00 | -20.01 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-186-5p | chr2:99117633-99117640 | 8mer-1a | chr2:99117624-99117640 | 151.00 | -8.93 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4691-5p | chr2:99118597-99118604 | 8mer-1a | chr2:99118595-99118618 | 159.00 | -17.50 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-3165 | chr2:99117574-99117581 | 8mer-1a | chr2:99117560-99117581 | 142.00 | -13.39 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4492 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-4496 | chr2:99117708-99117715 | 8mer-1a | chr2:99117703-99117726 | 157.00 | -18.93 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4498 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-3173-3p | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| MSBB | ENST00000355053 | 99127048 | 99127176 | hsa-miR-6085 | chr2:99127141-99127148 | 8mer-1a | chr2:99127124-99127148 | 164.00 | -22.74 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-762 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-6782-3p | chr2:99118670-99118677 | 8mer-1a | chr2:99118655-99118677 | 150.00 | -14.38 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4747-5p | chr2:99118614-99118621 | 8mer-1a | chr2:99118602-99118623 | 171.00 | -26.17 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-6792-3p | chr2:99118597-99118604 | 8mer-1a | chr2:99118595-99118618 | 159.00 | -17.50 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-5196-5p | chr2:99118614-99118621 | 8mer-1a | chr2:99118602-99118623 | 171.00 | -26.17 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-371a-5p | chr2:99117744-99117751 | 8mer-1a | chr2:99117735-99117756 | 156.00 | -13.06 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-1258 | chr2:99117711-99117718 | 8mer-1a | chr2:99117703-99117726 | 157.00 | -18.93 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-5001-5p | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4326 | chr2:99118599-99118606 | 8mer-1a | chr2:99118598-99118621 | 166.00 | -23.80 |
| MSBB | ENST00000355053 | 99127048 | 99127176 | hsa-miR-6813-5p | chr2:99127141-99127148 | 8mer-1a | chr2:99127124-99127148 | 164.00 | -22.74 |
| MSBB | ENST00000393483 | 99118551 | 99118686 | hsa-miR-8069 | chr2:99118633-99118640 | 8mer-1a | chr2:99118617-99118640 | 151.00 | -20.63 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-12118 | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| MSBB | ENST00000355053 | 99117544 | 99117759 | hsa-miR-6891-5p | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| MSBB | ENST00000355053 | 99127048 | 99127176 | hsa-miR-601 | chr2:99127146-99127153 | 8mer-1a | chr2:99127132-99127153 | 145.00 | -19.81 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-5697 | chr2:99117672-99117679 | 8mer-1a | chr2:99117655-99117680 | 157.00 | -19.58 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-6084 | chr2:99117567-99117574 | 8mer-1a | chr2:99117555-99117574 | 149.00 | -20.01 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-186-5p | chr2:99117633-99117640 | 8mer-1a | chr2:99117624-99117640 | 151.00 | -8.93 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4691-5p | chr2:99118597-99118604 | 8mer-1a | chr2:99118595-99118618 | 159.00 | -17.50 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-3165 | chr2:99117574-99117581 | 8mer-1a | chr2:99117560-99117581 | 142.00 | -13.39 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4492 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-4496 | chr2:99117708-99117715 | 8mer-1a | chr2:99117703-99117726 | 157.00 | -18.93 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4498 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-3173-3p | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| ROSMAP | ENST00000355053 | 99127048 | 99127176 | hsa-miR-6085 | chr2:99127141-99127148 | 8mer-1a | chr2:99127124-99127148 | 164.00 | -22.74 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-762 | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-6782-3p | chr2:99118670-99118677 | 8mer-1a | chr2:99118655-99118677 | 150.00 | -14.38 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4747-5p | chr2:99118614-99118621 | 8mer-1a | chr2:99118602-99118623 | 171.00 | -26.17 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-6792-3p | chr2:99118597-99118604 | 8mer-1a | chr2:99118595-99118618 | 159.00 | -17.50 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-5196-5p | chr2:99118614-99118621 | 8mer-1a | chr2:99118602-99118623 | 171.00 | -26.17 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-371a-5p | chr2:99117744-99117751 | 8mer-1a | chr2:99117735-99117756 | 156.00 | -13.06 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-1258 | chr2:99117711-99117718 | 8mer-1a | chr2:99117703-99117726 | 157.00 | -18.93 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-5001-5p | chr2:99118619-99118626 | 8mer-1a | chr2:99118605-99118626 | 166.00 | -29.88 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-4326 | chr2:99118599-99118606 | 8mer-1a | chr2:99118598-99118621 | 166.00 | -23.80 |
| ROSMAP | ENST00000355053 | 99127048 | 99127176 | hsa-miR-6813-5p | chr2:99127141-99127148 | 8mer-1a | chr2:99127124-99127148 | 164.00 | -22.74 |
| ROSMAP | ENST00000393483 | 99118551 | 99118686 | hsa-miR-8069 | chr2:99118633-99118640 | 8mer-1a | chr2:99118617-99118640 | 151.00 | -20.63 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-12118 | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| ROSMAP | ENST00000355053 | 99117544 | 99117759 | hsa-miR-6891-5p | chr2:99117690-99117697 | 8mer-1a | chr2:99117676-99117697 | 164.00 | -21.51 |
| ROSMAP | ENST00000355053 | 99127048 | 99127176 | hsa-miR-601 | chr2:99127146-99127153 | 8mer-1a | chr2:99127132-99127153 | 145.00 | -19.81 |
Top |
SNVs in the skipped exons for TSGA10 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
Top |
AD stage-associated exon skippint events for TSGA10 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for TSGA10 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
Top |
Correlation with RNA binding proteins (RBPs) for TSGA10 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
Top |
RelatedDrugs for TSGA10 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for TSGA10 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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