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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for TRIM26 |
 Gene summary |
| Gene information | Gene symbol | TRIM26 | Gene ID | 7726 |
| Gene name | tripartite motif containing 26 | |
| Synonyms | AFP|RNF95|ZNF173 | |
| Cytomap | 6p22.1 | |
| Type of gene | protein-coding | |
| Description | tripartite motif-containing protein 26RING finger protein 95acid finger proteinwidely expressed acid zinc finger proteinzinc finger protein 173 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| TRIM26 | GO:0045087 | innate immune response | 18248090 |
| TRIM26 | GO:0046597 | negative regulation of viral entry into host cell | 18248090 |
| TRIM26 | GO:0051091 | positive regulation of DNA-binding transcription factor activity | 23077300 |
| TRIM26 | GO:1902187 | negative regulation of viral release from host cell | 18248090 |
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Gene structures and expression levels for TRIM26 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000234127
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for TRIM26 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_104553 | chr6 | 30201035:30201138:30204656:30204765:30213305:30213365 | 30204656:30204765 |
| exon_skip_15025 | chr6 | 30198738:30199147:30204656:30204765:30213305:30213365 | 30204656:30204765 |
| exon_skip_215001 | chr6 | 30199246:30199264:30201035:30201138:30204656:30204765 | 30201035:30201138 |
| exon_skip_261334 | chr6 | 30190013:30190035:30196516:30196746:30198429:30198524 | 30196516:30196746 |
| exon_skip_294237 | chr6 | 30198666:30199153:30201035:30201138:30204656:30204765 | 30201035:30201138 |
| exon_skip_295142 | chr6 | 30198666:30199153:30201035:30201083:30204656:30204765 | 30201035:30201083 |
| exon_skip_90607 | chr6 | 30198666:30199153:30201035:30201138:30213305:30213365 | 30201035:30201138 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for TRIM26 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000453195 | 30201035 | 30201138 | 3UTR-3UTR |
| ENST00000454678 | 30204656 | 30204765 | 3UTR-3UTR |
| ENST00000437089 | 30196516 | 30196746 | In-frame |
| ENST00000453195 | 30196516 | 30196746 | In-frame |
| ENST00000454678 | 30196516 | 30196746 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000453195 | 30201035 | 30201138 | 3UTR-3UTR |
| ENST00000454678 | 30204656 | 30204765 | 3UTR-3UTR |
| ENST00000437089 | 30196516 | 30196746 | In-frame |
| ENST00000453195 | 30196516 | 30196746 | In-frame |
| ENST00000454678 | 30196516 | 30196746 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000437089 | 30201035 | 30201083 | 3UTR-3UTR |
| ENST00000453195 | 30201035 | 30201138 | 3UTR-3UTR |
| ENST00000454678 | 30201035 | 30201138 | 3UTR-3UTR |
| ENST00000454678 | 30204656 | 30204765 | 3UTR-3UTR |
| ENST00000437089 | 30196516 | 30196746 | In-frame |
| ENST00000453195 | 30196516 | 30196746 | In-frame |
| ENST00000454678 | 30196516 | 30196746 | In-frame |
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Infer the effects of exon skipping event on protein functional features for TRIM26 |
p-ENSG00000234127_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000437089 | 3267 | 539 | 30196516 | 30196746 | 744 | 973 | 178 | 254 |
| ENST00000453195 | 3335 | 539 | 30196516 | 30196746 | 812 | 1041 | 178 | 254 |
| ENST00000454678 | 3495 | 539 | 30196516 | 30196746 | 972 | 1201 | 178 | 254 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000437089 | 3267 | 539 | 30196516 | 30196746 | 744 | 973 | 178 | 254 |
| ENST00000453195 | 3335 | 539 | 30196516 | 30196746 | 812 | 1041 | 178 | 254 |
| ENST00000454678 | 3495 | 539 | 30196516 | 30196746 | 972 | 1201 | 178 | 254 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000437089 | 3267 | 539 | 30196516 | 30196746 | 744 | 973 | 178 | 254 |
| ENST00000453195 | 3335 | 539 | 30196516 | 30196746 | 812 | 1041 | 178 | 254 |
| ENST00000454678 | 3495 | 539 | 30196516 | 30196746 | 972 | 1201 | 178 | 254 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 1 | 539 | Chain | ID=PRO_0000056235;Note=Tripartite motif-containing protein 26 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 188 | 227 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
| Q12899 | 178 | 254 | 197 | 197 | Natural variant | ID=VAR_052138;Note=Q->H;Dbxref=dbSNP:rs17194565 |
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3'-UTR located exon skipping events that lost miRNA binding sites in TRIM26 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000437089 | 30201035 | 30201083 | hsa-miR-5581-5p | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-5581-5p | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| Mayo | ENST00000437089 | 30201035 | 30201083 | hsa-miR-4297 | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-4297 | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| Mayo | ENST00000437089 | 30201035 | 30201083 | hsa-miR-4703-3p | chr6:30201070-30201077 | 8mer-1a | chr6:30201067-30201088 | 157.00 | -19.17 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-4703-3p | chr6:30201070-30201077 | 8mer-1a | chr6:30201067-30201088 | 157.00 | -19.17 |
| Mayo | ENST00000454678 | 30204656 | 30204765 | hsa-miR-4306 | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-3173-5p | chr6:30201099-30201106 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-494-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-323b-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-410-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-6799-3p | chr6:30201099-30201106 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-6512-3p | chr6:30201122-30201129 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| Mayo | ENST00000454678 | 30204656 | 30204765 | hsa-miR-185-5p | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-6889-3p | chr6:30201103-30201110 | 8mer-1a | chr6:30201101-30201119 | 151.00 | -23.18 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-6529-3p | chr6:30201103-30201110 | 8mer-1a | chr6:30201101-30201119 | 151.00 | -23.18 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-7977 | chr6:30201083-30201090 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-3977 | chr6:30201130-30201137 | 8mer-1a | chr6:30201115-30201137 | 145.00 | -13.41 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-6720-5p | chr6:30201122-30201129 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| Mayo | ENST00000454678 | 30204656 | 30204765 | hsa-miR-6833-5p | chr6:30204718-30204725 | 8mer-1a | chr6:30204705-30204725 | 150.00 | -18.92 |
| Mayo | ENST00000454678 | 30204656 | 30204765 | hsa-miR-4644 | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| Mayo | ENST00000454678 | 30201035 | 30201138 | hsa-miR-6849-3p | chr6:30201121-30201128 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-5581-5p | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-4297 | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-4703-3p | chr6:30201070-30201077 | 8mer-1a | chr6:30201067-30201088 | 157.00 | -19.17 |
| MSBB | ENST00000454678 | 30204656 | 30204765 | hsa-miR-4306 | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-3173-5p | chr6:30201099-30201106 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-494-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-323b-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-410-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6799-3p | chr6:30201099-30201106 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6512-3p | chr6:30201122-30201129 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| MSBB | ENST00000454678 | 30204656 | 30204765 | hsa-miR-185-5p | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6889-3p | chr6:30201103-30201110 | 8mer-1a | chr6:30201101-30201119 | 151.00 | -23.18 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6529-3p | chr6:30201103-30201110 | 8mer-1a | chr6:30201101-30201119 | 151.00 | -23.18 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-7977 | chr6:30201083-30201090 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-3977 | chr6:30201130-30201137 | 8mer-1a | chr6:30201115-30201137 | 145.00 | -13.41 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6720-5p | chr6:30201122-30201129 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| MSBB | ENST00000454678 | 30204656 | 30204765 | hsa-miR-6833-5p | chr6:30204718-30204725 | 8mer-1a | chr6:30204705-30204725 | 150.00 | -18.92 |
| MSBB | ENST00000454678 | 30204656 | 30204765 | hsa-miR-4644 | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| MSBB | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6849-3p | chr6:30201121-30201128 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-5581-5p | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-4297 | chr6:30201064-30201071 | 8mer-1a | chr6:30201049-30201071 | 158.00 | -24.63 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-4703-3p | chr6:30201070-30201077 | 8mer-1a | chr6:30201067-30201088 | 157.00 | -19.17 |
| ROSMAP | ENST00000454678 | 30204656 | 30204765 | hsa-miR-4306 | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-3173-5p | chr6:30201099-30201106 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-494-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-323b-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-410-5p | chr6:30201091-30201098 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6799-3p | chr6:30201099-30201106 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6512-3p | chr6:30201122-30201129 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| ROSMAP | ENST00000454678 | 30204656 | 30204765 | hsa-miR-185-5p | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6889-3p | chr6:30201103-30201110 | 8mer-1a | chr6:30201101-30201119 | 151.00 | -23.18 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6529-3p | chr6:30201103-30201110 | 8mer-1a | chr6:30201101-30201119 | 151.00 | -23.18 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-7977 | chr6:30201083-30201090 | 8mer-1a | chr6:30201082-30201106 | 164.00 | -33.37 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-3977 | chr6:30201130-30201137 | 8mer-1a | chr6:30201115-30201137 | 145.00 | -13.41 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6720-5p | chr6:30201122-30201129 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
| ROSMAP | ENST00000454678 | 30204656 | 30204765 | hsa-miR-6833-5p | chr6:30204718-30204725 | 8mer-1a | chr6:30204705-30204725 | 150.00 | -18.92 |
| ROSMAP | ENST00000454678 | 30204656 | 30204765 | hsa-miR-4644 | chr6:30204748-30204755 | 8mer-1a | chr6:30204734-30204755 | 160.00 | -18.73 |
| ROSMAP | ENST00000453195 | 30201035 | 30201138 | hsa-miR-6849-3p | chr6:30201121-30201128 | 8mer-1a | chr6:30201108-30201129 | 162.00 | -27.46 |
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SNVs in the skipped exons for TRIM26 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for TRIM26 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for TRIM26 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| TC | exon_skip_104553 | rs2523990 | chr6:30109452 | 2.754909e-04 | 3.672848e-02 |
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Correlation with RNA binding proteins (RBPs) for TRIM26 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
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RelatedDrugs for TRIM26 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TRIM26 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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