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Open reading frame (ORF) annotation in the exon skipping event | |
3'-UTR located exon skipping events lost miRNA binding sites | |
Splicing Quantitative Trait Loci (sQTLs) in the skipped exons | |
Gene summary for STAT1 |
Gene summary |
Gene information | Gene symbol | STAT1 | Gene ID | 6772 |
Gene name | signal transducer and activator of transcription 1 | |
Synonyms | CANDF7|IMD31A|IMD31B|IMD31C|ISGF-3|STAT91 | |
Cytomap | 2q32.2 | |
Type of gene | protein-coding | |
Description | signal transducer and activator of transcription 1-alpha/betasignal transducer and activator of transcription 1, 91kDsignal transducer and activator of transcription 1, 91kDatranscription factor ISGF-3 components p91/p84 | |
Modification date | 20200329 | |
UniProtAcc | ||
Context |
Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Gene | GO ID | GO term | PubMed ID |
STAT1 | GO:0007259 | JAK-STAT cascade | 22002246 |
STAT1 | GO:0010742 | macrophage derived foam cell differentiation | 26504087 |
STAT1 | GO:0032727 | positive regulation of interferon-alpha production | 28753426 |
STAT1 | GO:0033209 | tumor necrosis factor-mediated signaling pathway | 10848577 |
STAT1 | GO:0045893 | positive regulation of transcription, DNA-templated | 10973496 |
STAT1 | GO:0051607 | defense response to virus | 28753426 |
STAT1 | GO:0060333 | interferon-gamma-mediated signaling pathway | 21268089 |
STAT1 | GO:0060337 | type I interferon signaling pathway | 23386060 |
STAT1 | GO:0071346 | cellular response to interferon-gamma | 23386060 |
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Gene structures and expression levels for STAT1 |
Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Differentially expressed gene analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
CB | DOWN | ENST00000540176.5 | STAT1-212:protein_coding:STAT1 | 1.227903e+02 | -1.993755e+00 | 3.012327e-05 | 2.674904e-04 |
CB | UP | ENST00000409465.5 | STAT1-204:protein_coding:STAT1 | 3.034031e+00 | 1.034602e+00 | 1.443477e-02 | 4.676598e-02 |
TC | UP | ENST00000464072.1 | STAT1-211:retained_intron:STAT1 | 1.231347e+00 | 9.867515e-01 | 4.377046e-03 | 3.029683e-02 |
TC | DOWN | ENST00000540176.5 | STAT1-212:protein_coding:STAT1 | 1.005093e+02 | -1.181574e+00 | 6.140300e-03 | 3.903661e-02 |
Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for STAT1 |
Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
All exon skipping events in AD cohorts. |
Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
exon_skip_117798 | chr2 | 190999626:190999704:191001074:191001163:191007563:191007661 | 191001074:191001163 |
exon_skip_137033 | chr2 | 191009876:191010004:191013525:191013678:191014018:191014168 | 191013525:191013678 |
exon_skip_157901 | chr2 | 190974830:190974932:190975812:190975887:190976840:190976922 | 190975812:190975887 |
exon_skip_183688 | chr2 | 190974830:190974932:190975310:190975388:190975812:190975887 | 190975310:190975388 |
exon_skip_206369 | chr2 | 191009876:191010004:191010367:191010449:191013525:191013674 | 191010367:191010449 |
exon_skip_233201 | chr2 | 190986854:190986947:190987039:190987068:190989615:190989674 | 190987039:190987068 |
exon_skip_252803 | chr2 | 190997856:190998007:190998217:190998308:190999626:190999697 | 190998217:190998308 |
exon_skip_291655 | chr2 | 190997856:190998007:190998217:190998308:190999626:190999704 | 190998217:190998308 |
exon_skip_50712 | chr2 | 191009981:191010004:191013525:191013678:191014018:191014211 | 191013525:191013678 |
exon_skip_66671 | chr2 | 190987039:190987068:190989615:190989674:190991228:190991320 | 190989615:190989674 |
exon_skip_87950 | chr2 | 191009876:191010004:191010367:191010449:191013525:191013678 | 191010367:191010449 |
exon_skip_92484 | chr2 | 191009981:191010004:191010367:191010449:191013525:191013678 | 191010367:191010449 |
Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for STAT1 |
Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000361099 | 191013525 | 191013678 | 3UTR-3UTR |
ENST00000361099 | 190975812 | 190975887 | Frame-shift |
ENST00000409465 | 190975812 | 190975887 | Frame-shift |
ENST00000361099 | 190998217 | 190998308 | Frame-shift |
ENST00000409465 | 190998217 | 190998308 | Frame-shift |
ENST00000361099 | 190989615 | 190989674 | In-frame |
ENST00000409465 | 190989615 | 190989674 | In-frame |
Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000361099 | 191013525 | 191013678 | 3UTR-3UTR |
ENST00000361099 | 190998217 | 190998308 | Frame-shift |
ENST00000409465 | 190998217 | 190998308 | Frame-shift |
ENST00000361099 | 190989615 | 190989674 | In-frame |
ENST00000409465 | 190989615 | 190989674 | In-frame |
Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000361099 | 191013525 | 191013678 | 3UTR-3UTR |
ENST00000361099 | 190975812 | 190975887 | Frame-shift |
ENST00000409465 | 190975812 | 190975887 | Frame-shift |
ENST00000361099 | 190998217 | 190998308 | Frame-shift |
ENST00000409465 | 190998217 | 190998308 | Frame-shift |
ENST00000361099 | 190987039 | 190987068 | In-frame |
ENST00000409465 | 190987039 | 190987068 | In-frame |
ENST00000361099 | 190989615 | 190989674 | In-frame |
ENST00000409465 | 190989615 | 190989674 | In-frame |
ENST00000361099 | 191001074 | 191001163 | In-frame |
ENST00000409465 | 191001074 | 191001163 | In-frame |
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Infer the effects of exon skipping event on protein functional features for STAT1 |
p-ENSG00000115415_img4.png |
Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000361099 | 4327 | 750 | 190989615 | 190989674 | 1426 | 1484 | 346 | 365 |
ENST00000409465 | 3114 | 750 | 190989615 | 190989674 | 1470 | 1528 | 346 | 365 |
Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000361099 | 4327 | 750 | 190989615 | 190989674 | 1426 | 1484 | 346 | 365 |
ENST00000409465 | 3114 | 750 | 190989615 | 190989674 | 1470 | 1528 | 346 | 365 |
Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000361099 | 4327 | 750 | 191001074 | 191001163 | 761 | 849 | 124 | 153 |
ENST00000409465 | 3114 | 750 | 191001074 | 191001163 | 805 | 893 | 124 | 153 |
ENST00000361099 | 4327 | 750 | 190989615 | 190989674 | 1426 | 1484 | 346 | 365 |
ENST00000409465 | 3114 | 750 | 190989615 | 190989674 | 1470 | 1528 | 346 | 365 |
ENST00000361099 | 4327 | 750 | 190987039 | 190987068 | 1486 | 1514 | 366 | 375 |
ENST00000409465 | 3114 | 750 | 190987039 | 190987068 | 1530 | 1558 | 366 | 375 |
Lost protein functional features of individual exon skipping events in ROSMAP. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
P42224 | 346 | 365 | 339 | 347 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 339 | 347 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 359 | 365 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 359 | 365 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 346 | 365 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 346 | 365 | 352 | 354 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 352 | 354 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 355 | 357 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 355 | 357 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
Lost protein functional features of individual exon skipping events in MSBB. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
P42224 | 346 | 365 | 339 | 347 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 339 | 347 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 359 | 365 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 359 | 365 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 346 | 365 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 346 | 365 | 352 | 354 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 352 | 354 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 355 | 357 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 355 | 357 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
Lost protein functional features of individual exon skipping events in Mayo. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
P42224 | 124 | 153 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 124 | 153 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 124 | 153 | 136 | 317 | Coiled coil | Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9630226;Dbxref=PMID:9630226 |
P42224 | 124 | 153 | 136 | 317 | Coiled coil | Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9630226;Dbxref=PMID:9630226 |
P42224 | 124 | 153 | 121 | 125 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1YVL |
P42224 | 124 | 153 | 121 | 125 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1YVL |
P42224 | 124 | 153 | 137 | 179 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 124 | 153 | 137 | 179 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 339 | 347 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 339 | 347 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 359 | 365 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 359 | 365 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 346 | 365 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 346 | 365 | 352 | 354 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 352 | 354 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 355 | 357 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 346 | 365 | 355 | 357 | Turn | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 366 | 375 | 374 | 376 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 366 | 375 | 374 | 376 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 366 | 375 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 366 | 375 | 2 | 750 | Chain | ID=PRO_0000182410;Note=Signal transducer and activator of transcription 1-alpha/beta |
P42224 | 366 | 375 | 370 | 373 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 366 | 375 | 370 | 373 | Helix | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:1BF5 |
P42224 | 366 | 375 | 366 | 366 | Modified residue | Note=N6-methyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28753426;Dbxref=PMID:28753426 |
P42224 | 366 | 375 | 366 | 366 | Modified residue | Note=N6-methyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28753426;Dbxref=PMID:28753426 |
P42224 | 366 | 375 | 366 | 366 | Mutagenesis | Note=No effect on IFN-alpha-induced STAT1 phosphorylation and nuclear translocation. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28753426;Dbxref=PMID:28753426 |
P42224 | 366 | 375 | 366 | 366 | Mutagenesis | Note=No effect on IFN-alpha-induced STAT1 phosphorylation and nuclear translocation. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28753426;Dbxref=PMID:28753426 |
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3'-UTR located exon skipping events that lost miRNA binding sites in STAT1 |
3'-UTR exon skipping evnets lost miRNA binding. |
Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-410-3p | chr2:191013610-191013617 | 8mer-1a | chr2:191013597-191013617 | 155.00 | -10.94 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-8078 | chr2:191013637-191013644 | 8mer-1a | chr2:191013624-191013647 | 166.00 | -21.46 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-4999-5p | chr2:191013660-191013667 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-4448 | chr2:191013566-191013573 | 8mer-1a | chr2:191013550-191013574 | 148.00 | -21.12 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-579-3p | chr2:191013666-191013673 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-3150b-5p | chr2:191013606-191013613 | 8mer-1a | chr2:191013592-191013613 | 164.00 | -21.01 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-3150a-5p | chr2:191013606-191013613 | 8mer-1a | chr2:191013592-191013613 | 164.00 | -21.01 |
Mayo | ENST00000361099 | 191013525 | 191013678 | hsa-miR-664b-3p | chr2:191013666-191013673 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-410-3p | chr2:191013610-191013617 | 8mer-1a | chr2:191013597-191013617 | 155.00 | -10.94 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-8078 | chr2:191013637-191013644 | 8mer-1a | chr2:191013624-191013647 | 166.00 | -21.46 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-4999-5p | chr2:191013660-191013667 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-4448 | chr2:191013566-191013573 | 8mer-1a | chr2:191013550-191013574 | 148.00 | -21.12 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-579-3p | chr2:191013666-191013673 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-3150b-5p | chr2:191013606-191013613 | 8mer-1a | chr2:191013592-191013613 | 164.00 | -21.01 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-3150a-5p | chr2:191013606-191013613 | 8mer-1a | chr2:191013592-191013613 | 164.00 | -21.01 |
MSBB | ENST00000361099 | 191013525 | 191013678 | hsa-miR-664b-3p | chr2:191013666-191013673 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-410-3p | chr2:191013610-191013617 | 8mer-1a | chr2:191013597-191013617 | 155.00 | -10.94 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-8078 | chr2:191013637-191013644 | 8mer-1a | chr2:191013624-191013647 | 166.00 | -21.46 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-4999-5p | chr2:191013660-191013667 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-4448 | chr2:191013566-191013573 | 8mer-1a | chr2:191013550-191013574 | 148.00 | -21.12 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-579-3p | chr2:191013666-191013673 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-3150b-5p | chr2:191013606-191013613 | 8mer-1a | chr2:191013592-191013613 | 164.00 | -21.01 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-3150a-5p | chr2:191013606-191013613 | 8mer-1a | chr2:191013592-191013613 | 164.00 | -21.01 |
ROSMAP | ENST00000361099 | 191013525 | 191013678 | hsa-miR-664b-3p | chr2:191013666-191013673 | 8mer-1a | chr2:191013649-191013673 | 154.00 | -17.51 |
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SNVs in the skipped exons for STAT1 |
- Differential PSIs between mutated versus non-mutated samples. |
- Depth of Coverage in the skipped exon of the mutated samples. |
- Sashimi plot in the skipped exon of the mutated samples. |
- Non-synonymous mutations located in the skipped exons. |
Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
- Non-synonymous mutations located in the skipped exons in CCLE. |
Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for STAT1 |
Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for STAT1 |
sQTL information located at the skipped exons. |
Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
CB | exon_skip_66671 | rs16833157 | chr2:190997672 | 1.055572e-12 | 1.575303e-09 |
CB | exon_skip_66671 | rs11885069 | chr2:191005898 | 1.055572e-12 | 1.575303e-09 |
CB | exon_skip_66671 | rs2066802 | chr2:191009941 | 1.667646e-09 | 1.319965e-06 |
CB | exon_skip_66671 | rs11693463 | chr2:191005185 | 3.437089e-07 | 1.441059e-04 |
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Correlation with RNA binding proteins (RBPs) for STAT1 |
Correlated RBP and related information. |
Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
IFG | RBMS2 | exon_skip_137033 | -4.802777e-01 | 9.689894e-03 |
STG | DAZAP1 | exon_skip_137033 | 4.106242e-01 | 2.293197e-04 |
STG | RBMS3 | exon_skip_137033 | 4.064437e-01 | 2.692933e-04 |
STG | TRNAU1AP | exon_skip_137033 | 4.179101e-01 | 1.724322e-04 |
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RelatedDrugs for STAT1 |
Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for STAT1 |
Diseases associated with this gene. (DisGeNet 4.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |