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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for DST |
 Gene summary |
| Gene information | Gene symbol | DST | Gene ID | 667 |
| Gene name | dystonin | |
| Synonyms | BP240|BPA|BPAG1|CATX-15|CATX15|D6S1101|DMH|DT|EBSB2|HSAN6|MACF2 | |
| Cytomap | 6p12.1 | |
| Type of gene | protein-coding | |
| Description | dystoninbullous pemphigoid antigen 1dystonia musculorum proteinhemidesmosomal plaque proteintrabeculin-beta | |
| Modification date | 20200313 | |
| UniProtAcc | A0A0U1RQJ2, A0A494C073, A0A494C1D7, A0A494C1U5, E7ERX3, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| DST | GO:0009611 | response to wounding | 19403692 |
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Gene structures and expression levels for DST |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000151914
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PCC | UP | ENST00000421834.6 | DST-207:protein_coding:DST | 1.752168e+01 | 2.530552e+01 | 5.047542e-22 | 5.477139e-17 |
| HCC | UP | ENST00000651289.1 | DST-236:protein_coding:DST | 8.773889e+01 | 1.820236e+00 | 7.174936e-04 | 2.718245e-02 |
| STG | UP | ENST00000421834.6 | DST-207:protein_coding:DST | 2.167355e+02 | 2.696025e+01 | 3.981474e-35 | 1.718006e-31 |
| CB | UP | ENST00000361203.7 | DST-204:protein_coding:DST | 8.651781e+02 | 8.119521e-01 | 1.299664e-05 | 1.314830e-04 |
| CB | UP | ENST00000312431.10 | DST-202:protein_coding:DST | 2.414286e+03 | 8.131208e-01 | 4.862903e-05 | 4.017243e-04 |
| CB | UP | ENST00000459869.2 | DST-210:retained_intron:DST | 1.007019e+00 | 8.655279e-01 | 1.016506e-02 | 3.522692e-02 |
| TC | UP | ENST00000361203.7 | DST-204:protein_coding:DST | 1.872560e+03 | 1.202262e+00 | 1.181661e-10 | 2.257563e-08 |
| TC | DOWN | ENST00000370788.6 | DST-206:protein_coding:DST | 3.190423e+03 | -9.451554e-01 | 4.984962e-05 | 9.285193e-04 |
| TC | UP | ENST00000524186.1 | DST-232:protein_coding:DST | 2.335037e+00 | 8.381379e-01 | 3.909106e-04 | 4.744562e-03 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for DST |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_118153 | chr6 | 56460243:56460254:56463046:56463156:56463565:56463764 | 56463046:56463156 |
| exon_skip_120537 | chr6 | 56528897:56528925:56529448:56529774:56529974:56530133 | 56529448:56529774 |
| exon_skip_133610 | chr6 | 56460131:56460254:56463046:56463156:56463565:56463764 | 56463046:56463156 |
| exon_skip_138613 | chr6 | 56562138:56562200:56568469:56568595:56569856:56570012 | 56568469:56568595 |
| exon_skip_139010 | chr6 | 56572127:56572266:56572747:56573064:56573679:56573887 | 56572747:56573064 |
| exon_skip_140405 | chr6 | 56600102:56600221:56601443:56601676:56602882:56603031 | 56601443:56601676 |
| exon_skip_140666 | chr6 | 56651132:56651244:56670641:56670807:56699653:56699745 | 56670641:56670807 |
| exon_skip_157332 | chr6 | 56636557:56636652:56639259:56639363:56639450:56639611 | 56639259:56639363 |
| exon_skip_161646 | chr6 | 56528841:56528925:56529974:56530133:56532344:56532501 | 56529974:56530133 |
| exon_skip_164730 | chr6 | 56468982:56468999:56469883:56469957:56470128:56470282 | 56469883:56469957 |
| exon_skip_165047 | chr6 | 56603564:56603713:56603837:56609344:56610427:56610562 | 56603837:56609344 |
| exon_skip_170759 | chr6 | 56704280:56704369:56735228:56735289:56851397:56851604 | 56735228:56735289 |
| exon_skip_176280 | chr6 | 56529974:56530133:56532344:56532510:56535122:56535292 | 56532344:56532510 |
| exon_skip_182069 | chr6 | 56459264:56459267:56460131:56460254:56463565:56463764 | 56460131:56460254 |
| exon_skip_182884 | chr6 | 56597740:56598006:56598476:56598709:56600069:56600221 | 56598476:56598709 |
| exon_skip_183228 | chr6 | 56598476:56598709:56600069:56600221:56610427:56610562 | 56600069:56600221 |
| exon_skip_188270 | chr6 | 56634132:56634258:56634462:56634616:56634801:56634953 | 56634462:56634616 |
| exon_skip_190943 | chr6 | 56466150:56466195:56468982:56468999:56469883:56469956 | 56468982:56468999 |
| exon_skip_193031 | chr6 | 56527493:56527734:56528841:56528925:56529974:56530132 | 56528841:56528925 |
| exon_skip_198848 | chr6 | 56639450:56639611:56639696:56639773:56639929:56640057 | 56639696:56639773 |
| exon_skip_206874 | chr6 | 56529448:56529774:56529974:56530133:56532344:56532510 | 56529974:56530133 |
| exon_skip_209370 | chr6 | 56460131:56460254:56463046:56463156:56463565:56463758 | 56463046:56463156 |
| exon_skip_225113 | chr6 | 56617200:56617418:56617986:56620715:56624530:56624628 | 56617986:56620715 |
| exon_skip_226572 | chr6 | 56600069:56600221:56601443:56601676:56602882:56603031 | 56601443:56601676 |
| exon_skip_238478 | chr6 | 56501520:56501693:56503997:56504098:56506443:56506544 | 56503997:56504098 |
| exon_skip_250500 | chr6 | 56536779:56536940:56552184:56553655:56555345:56555840 | 56552184:56553655 |
| exon_skip_266206 | chr6 | 56529448:56529774:56529974:56530133:56532344:56532501 | 56529974:56530133 |
| exon_skip_278930 | chr6 | 56704280:56704369:56735228:56735289:56843055:56843146 | 56735228:56735289 |
| exon_skip_284726 | chr6 | 56900421:56900621:56953785:56953819:56954407:56954628 | 56953785:56953819 |
| exon_skip_285077 | chr6 | 56735228:56735289:56851397:56851604:56900421:56900621 | 56851397:56851604 |
| exon_skip_32832 | chr6 | 56650926:56651032:56651132:56651244:56670641:56670807 | 56651132:56651244 |
| exon_skip_40500 | chr6 | 56527493:56527734:56528841:56528925:56529448:56529774 | 56528841:56528925 |
| exon_skip_43003 | chr6 | 56506443:56506544:56506667:56506789:56508529:56508755 | 56506667:56506789 |
| exon_skip_49379 | chr6 | 56466078:56466195:56468982:56468999:56469883:56469956 | 56468982:56468999 |
| exon_skip_53629 | chr6 | 56597896:56598006:56598476:56598709:56600069:56600221 | 56598476:56598709 |
| exon_skip_54614 | chr6 | 56670739:56670807:56699653:56699745:56701888:56701965 | 56699653:56699745 |
| exon_skip_56226 | chr6 | 56528841:56528925:56529448:56529774:56529974:56530133 | 56529448:56529774 |
| exon_skip_65372 | chr6 | 56463565:56463764:56464685:56464756:56466078:56466113 | 56464685:56464756 |
| exon_skip_68034 | chr6 | 56527493:56527734:56528841:56528925:56529974:56530133 | 56528841:56528925 |
| exon_skip_69400 | chr6 | 56611508:56611596:56614356:56614484:56624530:56624628 | 56614356:56614484 |
| exon_skip_70681 | chr6 | 56471106:56471268:56472059:56472222:56473873:56473990 | 56472059:56472222 |
| exon_skip_7897 | chr6 | 56463589:56463764:56464685:56464756:56466078:56466113 | 56464685:56464756 |
| exon_skip_88503 | chr6 | 56636557:56636652:56639259:56639363:56639450:56639600 | 56639259:56639363 |
| exon_skip_95062 | chr6 | 56528841:56528925:56529974:56530133:56532344:56532510 | 56529974:56530133 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_65372 | ROSMAP_DLPFC | 3.993722e-01 | 5.094167e-01 | -1.100445e-01 | 3.757031e-06 |
| exon_skip_65372 | ROSMAP_PCC | 5.033077e-01 | 6.228235e-01 | -1.195158e-01 | 2.520240e-05 |
| exon_skip_65372 | MSBB_STG | 4.686957e-01 | 6.212500e-01 | -1.525543e-01 | 4.741269e-03 |
| exon_skip_133610 | MSBB_PG | 7.338255e-01 | 5.789091e-01 | 1.549164e-01 | 2.516310e-06 |
| exon_skip_65372 | MSBB_PG | 3.583444e-01 | 4.962069e-01 | -1.378625e-01 | 1.665525e-06 |
| exon_skip_65372 | Mayo_CB | 3.654878e-01 | 5.025974e-01 | -1.371096e-01 | 9.306599e-06 |
| exon_skip_7897 | Mayo_TC | 3.651220e-01 | 4.774359e-01 | -1.123139e-01 | 1.245720e-04 |
| exon_skip_120537 | Mayo_TC | 4.345122e-01 | 3.097436e-01 | 1.247686e-01 | 3.029181e-06 |
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Open reading frame (ORF) annotation in the exon skipping event for DST |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
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Infer the effects of exon skipping event on protein functional features for DST |
p-ENSG00000151914_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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3'-UTR located exon skipping events that lost miRNA binding sites in DST |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for DST |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for DST |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
| ADstage | MSBB | PG | exon_skip_65372 | -4.129767e-01 | 5.160000e-10 | chr6 | - | 56463565 | 56463764 | 56464685 | 56464756 | 56466078 | 56466113 |
| ADstage | ROSMAP | PCC | exon_skip_65372 | -3.748678e-01 | 1.400000e-08 | chr6 | - | 56463565 | 56463764 | 56464685 | 56464756 | 56466078 | 56466113 |
| CDR | MSBB | PG | exon_skip_65372 | -3.473084e-01 | 2.580000e-07 | chr6 | - | 56463565 | 56463764 | 56464685 | 56464756 | 56466078 | 56466113 |
| CDR | MSBB | STG | exon_skip_65372 | -4.278246e-01 | 1.890000e-05 | chr6 | - | 56463565 | 56463764 | 56464685 | 56464756 | 56466078 | 56466113 |
| CDR | MSBB | STG | exon_skip_56226 | 3.056720e-01 | 2.886352e-03 | chr6 | - | 56528841 | 56528925 | 56529448 | 56529774 | 56529974 | 56530133 |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for DST |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| CB | exon_skip_182884 | rs2230862 | chr6:56619960 | 2.369769e-07 | 1.038553e-04 |
| CB | exon_skip_182884 | rs9370539 | chr6:56589583 | 2.679991e-07 | 1.166514e-04 |
| CB | exon_skip_182884 | rs10456736 | chr6:56571847 | 5.097039e-07 | 1.999308e-04 |
| CB | exon_skip_182884 | rs6459166 | chr6:56618003 | 5.330651e-07 | 2.073311e-04 |
| TC | exon_skip_53629 | rs9370539 | chr6:56589583 | 9.657815e-10 | 7.438904e-07 |
| TC | exon_skip_53629 | rs2230862 | chr6:56619960 | 1.415735e-09 | 1.034545e-06 |
| TC | exon_skip_53629 | rs6459166 | chr6:56618003 | 1.491944e-08 | 8.176755e-06 |
| TC | exon_skip_53629 | rs10456736 | chr6:56571847 | 1.690214e-08 | 9.212776e-06 |
| HCC | exon_skip_209370 | rs2273973 | chr6:56477183 | 2.768363e-04 | 2.114236e-02 |
| DLPFC | exon_skip_182884 | rs6459166 | chr6:56618003 | 1.479831e-05 | 1.585602e-03 |
| DLPFC | exon_skip_182884 | rs2230862 | chr6:56619960 | 1.822378e-05 | 1.909759e-03 |
| DLPFC | exon_skip_182884 | rs1884284 | chr6:56561102 | 1.102888e-04 | 9.188517e-03 |
| DLPFC | exon_skip_182884 | rs1884286 | chr6:56561173 | 1.102888e-04 | 9.188517e-03 |
| DLPFC | exon_skip_182884 | rs9370539 | chr6:56589583 | 1.642171e-04 | 1.297602e-02 |
| DLPFC | exon_skip_65372 | rs6459161 | chr6:56461967 | 1.887421e-04 | 1.461662e-02 |
| DLPFC | exon_skip_182884 | rs4715635 | chr6:56576351 | 2.324758e-04 | 1.748467e-02 |
| DLPFC | exon_skip_182884 | rs6929091 | chr6:56581237 | 3.120868e-04 | 2.224058e-02 |
| DLPFC | exon_skip_182884 | rs11969402 | chr6:56582008 | 3.120868e-04 | 2.224058e-02 |
| DLPFC | exon_skip_182884 | rs10456736 | chr6:56571847 | 4.122546e-04 | 2.766744e-02 |
| DLPFC | exon_skip_65372 | rs7755220 | chr6:56456142 | 7.507866e-04 | 4.450449e-02 |
| DLPFC | exon_skip_65372 | rs1570492 | chr6:56461097 | 7.507866e-04 | 4.450449e-02 |
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Correlation with RNA binding proteins (RBPs) for DST |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | SRSF2 | exon_skip_209370 | -4.016825e-01 | 1.539397e-07 |
| CB | SRSF11 | exon_skip_209370 | -4.408509e-01 | 6.037379e-09 |
| CB | HNRNPK | exon_skip_209370 | -5.338787e-01 | 4.275767e-13 |
| CB | PCBP2 | exon_skip_209370 | -5.930646e-01 | 1.771603e-16 |
| CB | PUM1 | exon_skip_209370 | -4.677070e-01 | 5.106040e-10 |
| CB | NUP42 | exon_skip_209370 | -5.257617e-01 | 1.109359e-12 |
| CB | RALYL | exon_skip_209370 | -7.142454e-01 | 4.140605e-26 |
| CB | HNRNPL | exon_skip_209370 | -4.360781e-01 | 9.161199e-09 |
| CB | PABPC1 | exon_skip_209370 | -4.955526e-01 | 3.112878e-11 |
| CB | SRSF9 | exon_skip_209370 | -5.500001e-01 | 5.957485e-14 |
| CB | MSI1 | exon_skip_56226 | 4.655513e-01 | 6.275733e-10 |
| CB | RALYL | exon_skip_56226 | -4.605690e-01 | 1.005400e-09 |
| CB | NOVA1 | exon_skip_56226 | -5.078250e-01 | 8.355706e-12 |
| DLPFC | MSI1 | exon_skip_56226 | 4.300045e-01 | 9.829227e-17 |
| DLPFC | TARDBP | exon_skip_209370 | -6.045021e-01 | 1.334781e-25 |
| DLPFC | SRSF2 | exon_skip_209370 | -7.198595e-01 | 4.338011e-40 |
| DLPFC | SRSF11 | exon_skip_209370 | 4.726460e-01 | 6.296671e-15 |
| DLPFC | CNOT4 | exon_skip_209370 | -6.569392e-01 | 2.134508e-31 |
| DLPFC | RBM5 | exon_skip_209370 | -6.493765e-01 | 1.721676e-30 |
| DLPFC | MBNL1 | exon_skip_209370 | -6.318508e-01 | 1.742153e-28 |
| DLPFC | HNRNPK | exon_skip_209370 | -6.877256e-01 | 2.252204e-35 |
| DLPFC | PCBP2 | exon_skip_209370 | -6.991121e-01 | 5.670415e-37 |
| DLPFC | SF1 | exon_skip_209370 | -6.693682e-01 | 6.042270e-33 |
| DLPFC | PUM1 | exon_skip_209370 | -7.443265e-01 | 3.798141e-44 |
| DLPFC | NUP42 | exon_skip_209370 | -6.955887e-01 | 1.804622e-36 |
| DLPFC | RALYL | exon_skip_209370 | -8.239599e-01 | 2.199212e-61 |
| DLPFC | HNRNPL | exon_skip_209370 | -7.656182e-01 | 4.488662e-48 |
| DLPFC | PABPC1 | exon_skip_209370 | -6.107750e-01 | 3.079901e-26 |
| DLPFC | EWSR1 | exon_skip_209370 | -7.034247e-01 | 1.343188e-37 |
| DLPFC | SRSF9 | exon_skip_209370 | -7.245066e-01 | 7.949817e-41 |
| DLPFC | SRSF5 | exon_skip_209370 | -6.815171e-01 | 1.562597e-34 |
| DLPFC | RC3H1 | exon_skip_65372 | 4.954848e-01 | 1.193427e-22 |
| DLPFC | EIF4B | exon_skip_65372 | 5.091283e-01 | 5.101762e-24 |
| FL | SRSF2 | exon_skip_133610 | -4.637495e-01 | 1.250496e-11 |
| FL | HNRNPK | exon_skip_133610 | -4.602830e-01 | 1.854470e-11 |
| FL | RALYL | exon_skip_133610 | -5.559151e-01 | 5.754289e-17 |
| FL | PTBP1 | exon_skip_133610 | 4.327941e-01 | 3.624265e-10 |
| FL | HNRNPL | exon_skip_133610 | -4.145702e-01 | 2.257025e-09 |
| FL | SRSF9 | exon_skip_133610 | -4.254525e-01 | 7.672182e-10 |
| FL | EIF4B | exon_skip_65372 | 5.861387e-01 | 1.448287e-19 |
| FL | NOVA1 | exon_skip_65372 | 4.103031e-01 | 2.124486e-09 |
| FL | RBFOX2 | exon_skip_56226 | -4.842944e-01 | 4.870873e-13 |
| FL | MSI1 | exon_skip_56226 | 5.375655e-01 | 3.193013e-16 |
| FL | ILF2 | exon_skip_56226 | -4.348066e-01 | 1.545528e-10 |
| FL | G3BP2 | exon_skip_56226 | -5.776187e-01 | 5.159419e-19 |
| FL | KHDRBS3 | exon_skip_56226 | -4.720804e-01 | 2.202090e-12 |
| FL | HNRNPA0 | exon_skip_56226 | -4.219799e-01 | 5.947508e-10 |
| FL | HNRNPC | exon_skip_56226 | -4.218620e-01 | 6.020094e-10 |
| FL | RALYL | exon_skip_56226 | -4.922699e-01 | 1.760009e-13 |
| FL | HNRNPH2 | exon_skip_56226 | -4.794844e-01 | 8.886806e-13 |
| FL | ESRP1 | exon_skip_56226 | -4.063109e-01 | 2.862159e-09 |
| HCC | SRSF11 | exon_skip_209370 | 4.565233e-01 | 1.846164e-15 |
| HCC | RBM5 | exon_skip_209370 | 5.756718e-01 | 1.705853e-25 |
| HCC | PCBP4 | exon_skip_209370 | 5.596500e-01 | 6.660734e-24 |
| HCC | SF1 | exon_skip_209370 | 4.377577e-01 | 3.299130e-14 |
| HCC | PTBP1 | exon_skip_209370 | 6.302500e-01 | 1.244975e-31 |
| HCC | PABPC1 | exon_skip_209370 | 4.277662e-01 | 1.426464e-13 |
| HCC | SRSF5 | exon_skip_209370 | 4.738826e-01 | 1.090121e-16 |
| HCC | DAZAP1 | exon_skip_65372 | -4.702927e-01 | 1.983073e-16 |
| HCC | RBM47 | exon_skip_65372 | -4.834329e-01 | 2.143508e-17 |
| HCC | MSI1 | exon_skip_56226 | 5.712259e-01 | 4.811936e-25 |
| HCC | RBM47 | exon_skip_56226 | 5.550771e-01 | 1.828828e-23 |
| HCC | SNRNP70 | exon_skip_56226 | 4.117769e-01 | 1.346398e-12 |
| HCC | HNRNPF | exon_skip_56226 | 5.339734e-01 | 1.590740e-21 |
| IFG | IGF2BP2 | exon_skip_133610 | 5.314996e-01 | 3.607603e-03 |
| IFG | RBM47 | exon_skip_133610 | 5.591549e-01 | 1.979898e-03 |
| IFG | RALYL | exon_skip_133610 | -5.185806e-01 | 4.695228e-03 |
| IFG | PTBP1 | exon_skip_133610 | 5.680208e-01 | 1.615423e-03 |
| IFG | DAZAP1 | exon_skip_65372 | -5.369661e-01 | 3.216925e-03 |
| IFG | RBM47 | exon_skip_65372 | -7.255414e-01 | 1.249694e-05 |
| IFG | TIA1 | exon_skip_56226 | 5.182247e-01 | 4.728758e-03 |
| IFG | IGF2BP3 | exon_skip_56226 | 4.062329e-01 | 3.194854e-02 |
| IFG | IGF2BP2 | exon_skip_56226 | 5.752587e-01 | 1.362415e-03 |
| IFG | RBM47 | exon_skip_56226 | 6.985325e-01 | 3.565497e-05 |
| IFG | G3BP2 | exon_skip_56226 | -5.264461e-01 | 4.004166e-03 |
| IFG | SNRNP70 | exon_skip_56226 | 4.971230e-01 | 7.116676e-03 |
| IFG | HNRNPH2 | exon_skip_56226 | -4.672517e-01 | 1.217801e-02 |
| IFG | ESRP2 | exon_skip_56226 | 4.658342e-01 | 1.247827e-02 |
| PCC | PCBP4 | exon_skip_133610 | 4.092692e-01 | 4.330711e-10 |
| PCC | PUM1 | exon_skip_133610 | -5.581502e-01 | 5.257455e-19 |
| PCC | RALYL | exon_skip_133610 | -5.337068e-01 | 3.153233e-17 |
| PCC | PTBP1 | exon_skip_133610 | 6.629380e-01 | 1.372835e-28 |
| PCC | PABPC1 | exon_skip_133610 | 4.534413e-01 | 2.672337e-12 |
| PCC | EIF4B | exon_skip_65372 | 4.247403e-01 | 7.920319e-11 |
| PCC | RBFOX2 | exon_skip_56226 | -5.156140e-01 | 5.309976e-16 |
| PCC | MSI1 | exon_skip_56226 | 5.341448e-01 | 2.938668e-17 |
| PCC | RBM47 | exon_skip_56226 | 4.802033e-01 | 8.410351e-14 |
| PCC | G3BP2 | exon_skip_56226 | -6.408780e-01 | 2.927638e-26 |
| PCC | RALYL | exon_skip_56226 | -4.575606e-01 | 1.599971e-12 |
| PCC | HNRNPF | exon_skip_56226 | 4.325428e-01 | 3.252167e-11 |
| PG | IGF2BP2 | exon_skip_133610 | 4.045150e-01 | 1.966225e-09 |
| PG | PUM1 | exon_skip_133610 | -4.166647e-01 | 5.689209e-10 |
| PG | RALYL | exon_skip_133610 | -5.331028e-01 | 2.242607e-16 |
| PG | RC3H1 | exon_skip_65372 | 4.062810e-01 | 1.036932e-09 |
| PG | HNRNPD | exon_skip_65372 | 4.814960e-01 | 1.579595e-13 |
| PG | EIF4B | exon_skip_65372 | 5.314039e-01 | 1.251209e-16 |
| PG | NOVA1 | exon_skip_65372 | 5.786000e-01 | 4.508791e-20 |
| PG | RBFOX2 | exon_skip_56226 | -6.225710e-01 | 8.027027e-24 |
| PG | ILF2 | exon_skip_56226 | -4.533786e-01 | 5.445579e-12 |
| PG | G3BP2 | exon_skip_56226 | -5.740783e-01 | 1.019033e-19 |
| PG | KHDRBS3 | exon_skip_56226 | -5.660162e-01 | 4.228826e-19 |
| PG | RALYL | exon_skip_56226 | -5.861047e-01 | 1.132610e-20 |
| PG | EWSR1 | exon_skip_56226 | -4.012288e-01 | 1.737792e-09 |
| PG | HNRNPH2 | exon_skip_56226 | -5.712913e-01 | 1.673971e-19 |
| PG | NOVA1 | exon_skip_56226 | -4.051323e-01 | 1.166989e-09 |
| STG | RALYL | exon_skip_133610 | -5.738176e-01 | 2.240982e-09 |
| STG | PTBP1 | exon_skip_133610 | 4.310701e-01 | 1.789584e-05 |
| STG | HNRNPD | exon_skip_65372 | 4.153579e-01 | 3.472312e-05 |
| STG | EIF4B | exon_skip_65372 | 4.604656e-01 | 3.414577e-06 |
| STG | NOVA1 | exon_skip_65372 | 6.123792e-01 | 6.902631e-11 |
| STG | RBFOX2 | exon_skip_56226 | -6.217375e-01 | 2.912100e-11 |
| STG | MSI1 | exon_skip_56226 | 4.954050e-01 | 4.449872e-07 |
| STG | IGF2BP2 | exon_skip_56226 | 4.315957e-01 | 1.564674e-05 |
| STG | ILF2 | exon_skip_56226 | -4.010056e-01 | 6.794150e-05 |
| STG | G3BP2 | exon_skip_56226 | -5.773954e-01 | 1.371405e-09 |
| STG | KHDRBS2 | exon_skip_56226 | -4.880131e-01 | 6.979552e-07 |
| STG | KHDRBS3 | exon_skip_56226 | -5.189145e-01 | 9.888558e-08 |
| STG | HNRNPA0 | exon_skip_56226 | -5.136093e-01 | 1.402350e-07 |
| STG | RALYL | exon_skip_56226 | -6.325020e-01 | 1.040792e-11 |
| STG | HNRNPH2 | exon_skip_56226 | -6.085393e-01 | 9.756079e-11 |
| STG | ESRP2 | exon_skip_56226 | 4.029081e-01 | 6.226634e-05 |
| STG | NOVA1 | exon_skip_56226 | -5.217065e-01 | 8.208114e-08 |
| TC | SRSF2 | exon_skip_118153 | -4.220807e-01 | 2.712171e-08 |
| TC | CNOT4 | exon_skip_118153 | -4.188124e-01 | 3.556491e-08 |
| TC | MBNL1 | exon_skip_118153 | -4.555881e-01 | 1.418598e-09 |
| TC | PUM1 | exon_skip_118153 | -6.954850e-01 | 1.888402e-24 |
| TC | NUP42 | exon_skip_118153 | -7.243883e-01 | 2.613422e-27 |
| TC | RALYL | exon_skip_118153 | -9.182262e-01 | 1.923476e-65 |
| TC | SRSF9 | exon_skip_118153 | -4.259722e-01 | 1.956715e-08 |
| TC | HNRNPD | exon_skip_7897 | 6.348359e-01 | 1.978558e-19 |
| TC | NOVA1 | exon_skip_7897 | 7.673448e-01 | 2.653068e-32 |
| TC | MSI1 | exon_skip_120537 | 6.797480e-01 | 4.950048e-23 |
| TC | RBM47 | exon_skip_120537 | 4.549393e-01 | 1.506650e-09 |
| TC | NOVA1 | exon_skip_120537 | -5.083583e-01 | 6.766856e-12 |
Top |
RelatedDrugs for DST |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for DST |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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