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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for UPF3A |
 Gene summary |
| Gene information | Gene symbol | UPF3A | Gene ID | 65110 |
| Gene name | UPF3A regulator of nonsense mediated mRNA decay | |
| Synonyms | HUPF3A|RENT3A|UPF3 | |
| Cytomap | 13q34 | |
| Type of gene | protein-coding | |
| Description | regulator of nonsense transcripts 3AUPF3 regulator of nonsense transcripts homolog AhUpf3nonsense mRNA reducing factor 3Aup-frameshift suppressor 3 homolog A | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| UPF3A | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 16601204 |
| UPF3A | GO:0045727 | positive regulation of translation | 16601204 |
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Gene structures and expression levels for UPF3A |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000169062
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for UPF3A |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_100316 | chr13 | 114298840:114299000:114301731:114302025:114304789:114304949 | 114301731:114302025 |
| exon_skip_109309 | chr13 | 114291634:114291792:114301731:114301867:114304789:114304949 | 114301731:114301867 |
| exon_skip_114024 | chr13 | 114282837:114282943:114286519:114286629:114291489:114291544 | 114286519:114286629 |
| exon_skip_128664 | chr13 | 114282906:114282943:114286259:114286400:114286519:114286629 | 114286259:114286400 |
| exon_skip_151518 | chr13 | 114282021:114282127:114282837:114282943:114286302:114286400 | 114282837:114282943 |
| exon_skip_159768 | chr13 | 114286519:114286629:114291489:114291544:114291634:114291697 | 114291489:114291544 |
| exon_skip_160076 | chr13 | 114282906:114282943:114286519:114286629:114291489:114291544 | 114286519:114286629 |
| exon_skip_164259 | chr13 | 114282021:114282127:114282837:114282943:114286519:114286607 | 114282837:114282943 |
| exon_skip_173758 | chr13 | 114282906:114282943:114286302:114286400:114286519:114286629 | 114286302:114286400 |
| exon_skip_186722 | chr13 | 114291743:114291792:114298840:114299000:114301731:114301756 | 114298840:114299000 |
| exon_skip_192534 | chr13 | 114282021:114282127:114282837:114282943:114286519:114286629 | 114282837:114282943 |
| exon_skip_196151 | chr13 | 114286519:114286629:114291489:114291544:114291634:114291718 | 114291489:114291544 |
| exon_skip_200076 | chr13 | 114282879:114282943:114286302:114286400:114286519:114286629 | 114286302:114286400 |
| exon_skip_202996 | chr13 | 114282837:114282943:114286302:114286400:114286519:114286629 | 114286302:114286400 |
| exon_skip_211845 | chr13 | 114286525:114286629:114291489:114291544:114291634:114291718 | 114291489:114291544 |
| exon_skip_215458 | chr13 | 114291727:114291792:114298840:114299000:114301731:114301756 | 114298840:114299000 |
| exon_skip_241177 | chr13 | 114282837:114282943:114286259:114286400:114286519:114286607 | 114286259:114286400 |
| exon_skip_246965 | chr13 | 114281645:114281846:114282021:114282127:114282837:114282943 | 114282021:114282127 |
| exon_skip_249910 | chr13 | 114282879:114282943:114286259:114286400:114286519:114286629 | 114286259:114286400 |
| exon_skip_251217 | chr13 | 114298952:114299000:114301731:114302025:114304789:114304949 | 114301731:114302025 |
| exon_skip_264316 | chr13 | 114282879:114282943:114286519:114286629:114291489:114291544 | 114286519:114286629 |
| exon_skip_271899 | chr13 | 114286519:114286629:114291605:114291792:114298840:114299000 | 114291605:114291792 |
| exon_skip_272703 | chr13 | 114282837:114282943:114286302:114286400:114286519:114286607 | 114286302:114286400 |
| exon_skip_273733 | chr13 | 114282837:114282943:114291489:114291544:114291634:114291718 | 114291489:114291544 |
| exon_skip_281716 | chr13 | 114291634:114291792:114298840:114299000:114301731:114301756 | 114298840:114299000 |
| exon_skip_281816 | chr13 | 114298849:114299000:114301731:114302025:114304789:114304949 | 114301731:114302025 |
| exon_skip_36698 | chr13 | 114281720:114281846:114282837:114282943:114286302:114286400 | 114282837:114282943 |
| exon_skip_39734 | chr13 | 114282837:114282943:114286259:114286400:114286519:114286629 | 114286259:114286400 |
| exon_skip_58368 | chr13 | 114282021:114282127:114282837:114282943:114291489:114291544 | 114282837:114282943 |
| exon_skip_94587 | chr13 | 114281720:114281846:114282021:114282127:114282837:114282943 | 114282021:114282127 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_192534 | Mayo_CB | 5.948780e-01 | 7.811688e-01 | -1.862908e-01 | 3.948196e-07 |
| exon_skip_42175 | Mayo_CB | 6.863415e-01 | 8.435065e-01 | -1.571650e-01 | 7.983023e-07 |
| exon_skip_123200 | Mayo_CB | 5.371951e-01 | 7.144156e-01 | -1.772205e-01 | 9.237781e-08 |
| exon_skip_46508 | Mayo_TC | 3.837681e-01 | 4.863158e-01 | -1.025477e-01 | 3.195193e-04 |
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Open reading frame (ORF) annotation in the exon skipping event for UPF3A |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000375299 | 114282837 | 114282943 | Frame-shift |
| ENST00000375299 | 114291489 | 114291544 | Frame-shift |
| ENST00000375299 | 114298840 | 114299000 | Frame-shift |
| ENST00000375299 | 114301731 | 114302025 | Frame-shift |
| ENST00000375299 | 114286302 | 114286400 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000375299 | 114282837 | 114282943 | Frame-shift |
| ENST00000375299 | 114291489 | 114291544 | Frame-shift |
| ENST00000375299 | 114298840 | 114299000 | Frame-shift |
| ENST00000375299 | 114301731 | 114302025 | Frame-shift |
| ENST00000375299 | 114286302 | 114286400 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000375299 | 114282837 | 114282943 | Frame-shift |
| ENST00000375299 | 114291489 | 114291544 | Frame-shift |
| ENST00000375299 | 114298840 | 114299000 | Frame-shift |
| ENST00000375299 | 114301731 | 114302025 | Frame-shift |
| ENST00000375299 | 114286302 | 114286400 | In-frame |
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Infer the effects of exon skipping event on protein functional features for UPF3A |
p-ENSG00000169062_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000375299 | 2404 | 476 | 114286302 | 114286400 | 479 | 576 | 141 | 173 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000375299 | 2404 | 476 | 114286302 | 114286400 | 479 | 576 | 141 | 173 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000375299 | 2404 | 476 | 114286302 | 114286400 | 479 | 576 | 141 | 173 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9H1J1 | 141 | 173 | 1 | 325 | Alternative sequence | ID=VSP_012961;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9H1J1 | 141 | 173 | 141 | 173 | Alternative sequence | ID=VSP_012962;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9H1J1 | 141 | 173 | 143 | 150 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2L08 |
| Q9H1J1 | 141 | 173 | 1 | 476 | Chain | ID=PRO_0000215296;Note=Regulator of nonsense transcripts 3A |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9H1J1 | 141 | 173 | 1 | 325 | Alternative sequence | ID=VSP_012961;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9H1J1 | 141 | 173 | 141 | 173 | Alternative sequence | ID=VSP_012962;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9H1J1 | 141 | 173 | 143 | 150 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2L08 |
| Q9H1J1 | 141 | 173 | 1 | 476 | Chain | ID=PRO_0000215296;Note=Regulator of nonsense transcripts 3A |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9H1J1 | 141 | 173 | 1 | 325 | Alternative sequence | ID=VSP_012961;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9H1J1 | 141 | 173 | 141 | 173 | Alternative sequence | ID=VSP_012962;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9H1J1 | 141 | 173 | 143 | 150 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2L08 |
| Q9H1J1 | 141 | 173 | 1 | 476 | Chain | ID=PRO_0000215296;Note=Regulator of nonsense transcripts 3A |
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3'-UTR located exon skipping events that lost miRNA binding sites in UPF3A |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for UPF3A |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for UPF3A |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for UPF3A |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| CB | exon_skip_186722 | rs7322952 | chr13:114210981 | 6.159422e-06 | 1.724475e-03 |
| CB | exon_skip_186722 | rs3993426 | chr13:114309842 | 7.283819e-05 | 1.340318e-02 |
| CB | exon_skip_186722 | rs7998976 | chr13:114219408 | 8.439129e-05 | 1.515857e-02 |
| TC | exon_skip_281716 | rs7322952 | chr13:114210981 | 5.280156e-05 | 9.865015e-03 |
| TC | exon_skip_281716 | rs7998976 | chr13:114219408 | 1.956771e-04 | 2.776417e-02 |
| HCC | exon_skip_281716 | rs9525316 | chr13:114296760 | 4.320123e-10 | 1.375334e-07 |
| HCC | exon_skip_281716 | rs7316983 | chr13:114309403 | 6.247949e-10 | 1.939258e-07 |
| PCC | exon_skip_281716 | rs7316983 | chr13:114309403 | 1.843670e-04 | 2.814048e-02 |
| DLPFC | exon_skip_281716 | rs7316983 | chr13:114309403 | 6.248358e-15 | 3.754476e-12 |
| DLPFC | exon_skip_281716 | rs9525316 | chr13:114296760 | 1.573234e-13 | 7.891822e-11 |
| DLPFC | exon_skip_281716 | rs9525326 | chr13:114310240 | 4.985930e-05 | 4.624423e-03 |
| DLPFC | exon_skip_281716 | rs7322952 | chr13:114210981 | 5.326731e-04 | 3.390980e-02 |
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Correlation with RNA binding proteins (RBPs) for UPF3A |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | RBM4 | exon_skip_206420 | -4.676569e-01 | 1.204036e-07 |
| CB | DAZAP1 | exon_skip_85722 | -4.801279e-01 | 1.729226e-10 |
| CB | PCBP1 | exon_skip_85722 | -4.935702e-01 | 4.418544e-11 |
| CB | TRA2A | exon_skip_85722 | -5.559801e-01 | 3.368113e-14 |
| CB | HNRNPA2B1 | exon_skip_85722 | -5.038730e-01 | 1.490524e-11 |
| CB | RBM45 | exon_skip_85722 | 4.162613e-01 | 5.336863e-08 |
| CB | EIF4G2 | exon_skip_85722 | -4.165009e-01 | 5.234497e-08 |
| CB | PTBP1 | exon_skip_85722 | -4.178799e-01 | 4.681022e-08 |
| CB | HNRNPF | exon_skip_85722 | -4.029399e-01 | 1.530064e-07 |
| CB | RBM4 | exon_skip_85722 | -5.728330e-01 | 3.707295e-15 |
| CB | RBM4B | exon_skip_85722 | -5.394623e-01 | 2.604540e-13 |
| CB | DAZAP1 | exon_skip_2313 | -4.377974e-01 | 1.096581e-07 |
| CB | TARDBP | exon_skip_2313 | -4.126954e-01 | 6.557449e-07 |
| CB | ELAVL1 | exon_skip_2313 | -4.579732e-01 | 2.337210e-08 |
| CB | SAMD4A | exon_skip_2313 | -4.356082e-01 | 1.289150e-07 |
| CB | CNOT4 | exon_skip_2313 | -4.637990e-01 | 1.467658e-08 |
| CB | PCBP1 | exon_skip_2313 | -5.067005e-01 | 3.599395e-10 |
| CB | PCBP4 | exon_skip_2313 | 4.016954e-01 | 1.373193e-06 |
| CB | TRA2A | exon_skip_2313 | -5.213747e-01 | 8.958488e-11 |
| CB | FUBP1 | exon_skip_2313 | -4.214431e-01 | 3.574178e-07 |
| CB | KHSRP | exon_skip_2313 | -4.190358e-01 | 4.231050e-07 |
| CB | HNRNPA2B1 | exon_skip_2313 | -4.755938e-01 | 5.568955e-09 |
| CB | HNRNPAB | exon_skip_2313 | -4.306845e-01 | 1.847301e-07 |
| CB | HNRNPC | exon_skip_2313 | -4.415999e-01 | 8.256848e-08 |
| CB | EIF4G2 | exon_skip_2313 | -4.239933e-01 | 2.984885e-07 |
| CB | HNRNPF | exon_skip_2313 | -4.200348e-01 | 3.945571e-07 |
| CB | RBM4 | exon_skip_2313 | -4.925106e-01 | 1.299140e-09 |
| CB | RBM4B | exon_skip_2313 | -4.990296e-01 | 7.256647e-10 |
| CB | DAZAP1 | exon_skip_32110 | -4.798801e-01 | 1.772299e-10 |
| CB | TARDBP | exon_skip_32110 | -4.451733e-01 | 4.609867e-09 |
| CB | ELAVL1 | exon_skip_32110 | -4.656251e-01 | 7.063133e-10 |
| CB | ZNF638 | exon_skip_32110 | -4.401415e-01 | 7.178266e-09 |
| CB | SAMD4A | exon_skip_32110 | -4.749052e-01 | 2.892260e-10 |
| CB | U2AF2 | exon_skip_32110 | -5.589134e-01 | 2.314499e-14 |
| CB | CNOT4 | exon_skip_32110 | -4.918748e-01 | 5.265562e-11 |
| CB | FXR2 | exon_skip_32110 | -4.117189e-01 | 7.682448e-08 |
| CB | PCBP1 | exon_skip_32110 | -4.929736e-01 | 4.700343e-11 |
| CB | PCBP4 | exon_skip_32110 | 4.180076e-01 | 4.632688e-08 |
| CB | TRA2A | exon_skip_32110 | -5.580086e-01 | 2.599460e-14 |
| CB | FUBP1 | exon_skip_32110 | -4.569257e-01 | 1.592616e-09 |
| CB | KHSRP | exon_skip_32110 | -4.390382e-01 | 7.902721e-09 |
| CB | HNRNPA2B1 | exon_skip_32110 | -5.030323e-01 | 1.630954e-11 |
| CB | RBM45 | exon_skip_32110 | 4.093942e-01 | 9.237792e-08 |
| CB | HNRNPAB | exon_skip_32110 | -4.463687e-01 | 4.145093e-09 |
| CB | HNRNPC | exon_skip_32110 | -4.454865e-01 | 4.483437e-09 |
| CB | EIF4G2 | exon_skip_32110 | -4.165209e-01 | 5.226024e-08 |
| CB | PTBP1 | exon_skip_32110 | -4.146972e-01 | 6.053771e-08 |
| CB | SRSF4 | exon_skip_32110 | -4.429702e-01 | 5.601194e-09 |
| CB | HNRNPF | exon_skip_32110 | -4.016687e-01 | 1.687824e-07 |
| CB | RBM4 | exon_skip_32110 | -5.700990e-01 | 5.348659e-15 |
| CB | RBM4B | exon_skip_32110 | -5.421347e-01 | 1.884877e-13 |
| CB | NUP42 | exon_skip_192534 | 4.721766e-01 | 3.314000e-10 |
| CB | PTBP1 | exon_skip_192534 | -4.553837e-01 | 1.628877e-09 |
| CB | RBM23 | exon_skip_192534 | -4.409746e-01 | 5.971960e-09 |
| CB | TARDBP | exon_skip_46508 | -4.371383e-01 | 1.608034e-08 |
| CB | PABPN1L | exon_skip_46508 | 4.248874e-01 | 4.397208e-08 |
| CB | SAMD4A | exon_skip_46508 | -4.400115e-01 | 1.262710e-08 |
| CB | CNOT4 | exon_skip_46508 | -4.377235e-01 | 1.531054e-08 |
| CB | MBNL1 | exon_skip_46508 | -4.144591e-01 | 1.003785e-07 |
| CB | KHDRBS3 | exon_skip_46508 | -4.031955e-01 | 2.373511e-07 |
| CB | HNRNPC | exon_skip_46508 | -5.283219e-01 | 2.240051e-12 |
| CB | RBM23 | exon_skip_46508 | -4.183337e-01 | 7.410882e-08 |
| CB | DAZAP1 | exon_skip_42175 | -4.230900e-01 | 2.759614e-08 |
| CB | TARDBP | exon_skip_42175 | -4.734107e-01 | 2.937920e-10 |
| CB | ZNF638 | exon_skip_42175 | -6.344349e-01 | 2.748124e-19 |
| CB | RBM6 | exon_skip_42175 | -5.115450e-01 | 5.550140e-12 |
| CB | SAMD4A | exon_skip_42175 | -5.661147e-01 | 7.453620e-15 |
| CB | U2AF2 | exon_skip_42175 | -6.490981e-01 | 2.178938e-20 |
| CB | CNOT4 | exon_skip_42175 | -5.313983e-01 | 5.737373e-13 |
| CB | RBM3 | exon_skip_42175 | 5.381938e-01 | 2.548943e-13 |
| CB | PCBP1 | exon_skip_42175 | -4.034371e-01 | 1.343104e-07 |
| CB | PCBP4 | exon_skip_42175 | 5.306494e-01 | 6.267082e-13 |
| CB | TRA2A | exon_skip_42175 | -5.869919e-01 | 4.241084e-16 |
| CB | FUBP1 | exon_skip_42175 | -5.047751e-01 | 1.164292e-11 |
| CB | HNRNPA2B1 | exon_skip_42175 | -5.544240e-01 | 3.404630e-14 |
| CB | RBM45 | exon_skip_42175 | 6.983284e-01 | 1.434056e-24 |
| CB | HNRNPC | exon_skip_42175 | -5.009100e-01 | 1.764470e-11 |
| CB | NUP42 | exon_skip_42175 | 4.824100e-01 | 1.202830e-10 |
| CB | PTBP1 | exon_skip_42175 | -4.406461e-01 | 6.147181e-09 |
| CB | RBM23 | exon_skip_42175 | -4.320628e-01 | 1.294679e-08 |
| CB | SRSF4 | exon_skip_42175 | -4.426690e-01 | 5.141865e-09 |
| CB | RBM4B | exon_skip_42175 | -5.362440e-01 | 3.223029e-13 |
| CB | PCBP4 | exon_skip_200076 | 4.352032e-01 | 9.882089e-09 |
| CB | NUP42 | exon_skip_200076 | 4.301959e-01 | 1.518241e-08 |
| CB | PABPC1 | exon_skip_200076 | 4.182565e-01 | 4.111288e-08 |
| CB | PCBP4 | exon_skip_123200 | 5.830298e-01 | 7.423212e-16 |
| CB | TRA2A | exon_skip_123200 | -5.516818e-01 | 4.820757e-14 |
| CB | NUP42 | exon_skip_123200 | 4.823069e-01 | 1.215370e-10 |
| DLPFC | RBM3 | exon_skip_42175 | 5.477029e-01 | 4.379539e-28 |
| DLPFC | DAZAP1 | exon_skip_272703 | 4.092496e-01 | 3.142296e-11 |
| DLPFC | SRSF2 | exon_skip_272703 | 4.342335e-01 | 1.351636e-12 |
| DLPFC | ILF2 | exon_skip_272703 | 4.107739e-01 | 2.612608e-11 |
| DLPFC | PCBP4 | exon_skip_272703 | 4.148348e-01 | 1.590356e-11 |
| DLPFC | KHDRBS2 | exon_skip_272703 | 5.223664e-01 | 2.052860e-18 |
| DLPFC | SRSF9 | exon_skip_272703 | 4.190404e-01 | 9.443999e-12 |
| DLPFC | SART3 | exon_skip_272703 | 4.343122e-01 | 1.337750e-12 |
| HCC | MSI1 | exon_skip_42175 | -4.220115e-01 | 3.584749e-13 |
| HCC | SAMD4A | exon_skip_42175 | -5.292045e-01 | 4.936682e-21 |
| HCC | RBM3 | exon_skip_42175 | 5.552620e-01 | 2.115428e-23 |
| HCC | EIF4G2 | exon_skip_42175 | -4.228074e-01 | 3.203992e-13 |
| HCC | PTBP1 | exon_skip_42175 | -4.132356e-01 | 1.212814e-12 |
| HCC | RBM4B | exon_skip_42175 | -4.129191e-01 | 1.266481e-12 |
| HCC | MSI1 | exon_skip_202996 | -4.525388e-01 | 4.900488e-15 |
| IFG | IGF2BP2 | exon_skip_192534 | 5.101757e-01 | 2.154860e-02 |
| IFG | TRNAU1AP | exon_skip_192534 | -4.448007e-01 | 4.940363e-02 |
| IFG | RALYL | exon_skip_192534 | -4.759225e-01 | 3.391189e-02 |
| IFG | PTBP1 | exon_skip_192534 | -4.783927e-01 | 3.286798e-02 |
| IFG | RBM23 | exon_skip_192534 | -4.858033e-01 | 2.988629e-02 |
| IFG | CPEB1 | exon_skip_192534 | -5.953148e-01 | 5.618938e-03 |
| PCC | SAMD4A | exon_skip_42175 | -4.561353e-01 | 2.425590e-12 |
| PCC | RBM3 | exon_skip_42175 | 6.174637e-01 | 8.900867e-24 |
| PCC | MSI1 | exon_skip_202996 | -4.183982e-01 | 2.158056e-10 |
| TC | RBMS2 | exon_skip_192534 | -4.270706e-01 | 1.783118e-08 |
| TC | PCBP4 | exon_skip_46508 | 4.224805e-01 | 8.315895e-07 |
| TC | HNRNPAB | exon_skip_46508 | -4.126565e-01 | 1.573658e-06 |
| TC | RBMS2 | exon_skip_42175 | -4.918985e-01 | 3.957415e-11 |
| TC | MSI1 | exon_skip_42175 | -4.302803e-01 | 1.356610e-08 |
| TC | SAMD4A | exon_skip_42175 | -5.160840e-01 | 2.857491e-12 |
| TC | RBM3 | exon_skip_42175 | 6.392546e-01 | 9.296878e-20 |
| TC | PTBP1 | exon_skip_42175 | -4.775798e-01 | 1.706980e-10 |
| TC | NOVA1 | exon_skip_42175 | 4.436798e-01 | 4.200139e-09 |
| TC | MSI1 | exon_skip_173758 | -4.788082e-01 | 1.509774e-10 |
| TC | SRSF2 | exon_skip_123200 | 4.851031e-01 | 1.586190e-10 |
| TC | MSI1 | exon_skip_123200 | -4.098939e-01 | 1.180877e-07 |
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RelatedDrugs for UPF3A |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UPF3A |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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