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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for FAM111A |
 Gene summary |
| Gene information | Gene symbol | FAM111A | Gene ID | 63901 |
| Gene name | family with sequence similarity 111 member A | |
| Synonyms | GCLEB|KCS2 | |
| Cytomap | 11q12.1 | |
| Type of gene | protein-coding | |
| Description | protein FAM111A | |
| Modification date | 20200320 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for FAM111A |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000166801
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
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| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PG | UP | ENST00000361723.7 | FAM111A-201:protein_coding:FAM111A | 3.809986e+01 | 1.314198e+00 | 2.293383e-05 | 9.249186e-04 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for FAM111A |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_26266 | chr11 | 59143083:59143304:59143497:59145856:59148836:59148953 | 59143497:59145856 |
| exon_skip_280133 | chr11 | 59143083:59143304:59145827:59145856:59148836:59148953 | 59145827:59145856 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |