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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for CCNB1IP1 |
 Gene summary |
| Gene information | Gene symbol | CCNB1IP1 | Gene ID | 57820 |
| Gene name | cyclin B1 interacting protein 1 | |
| Synonyms | C14orf18|HEI10 | |
| Cytomap | 14q11.2 | |
| Type of gene | protein-coding | |
| Description | E3 ubiquitin-protein ligase CCNB1IP1RING-type E3 ubiquitin transferase CCNB1IP1cyclin B1 interacting protein 1, E3 ubiquitin protein ligaseepididymis secretory sperm binding proteinhuman enhancer of invasion 10 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for CCNB1IP1 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000100814
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
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| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | DOWN | ENST00000353689.8 | CCNB1IP1-201:protein_coding:CCNB1IP1 | 1.736020e+02 | -2.232052e+00 | 1.987907e-09 | 7.697126e-08 |
| CB | DOWN | ENST00000554184.5 | CCNB1IP1-210:nonsense_mediated_decay:CCNB1IP1 | 7.848831e+00 | -9.374355e-01 | 9.879699e-04 | 5.112838e-03 |
| TC | DOWN | ENST00000353689.8 | CCNB1IP1-201:protein_coding:CCNB1IP1 | 1.267959e+02 | -1.610762e+00 | 6.228022e-04 | 6.834478e-03 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for CCNB1IP1 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_105445 | chr14 | 20313637:20313801:20315781:20315850:20316227:20316265 | 20315781:20315850 |
| exon_skip_106761 | chr14 | 20314211:20314649:20315485:20315618:20316227:20316265 | 20315485:20315618 |
| exon_skip_11686 | chr14 | 20326716:20326793:20329174:20329373:20333254:20333312 | 20329174:20329373 |
| exon_skip_130432 | chr14 | 20316227:20316560:20318256:20318470:20325539:20325653 | 20318256:20318470 |
| exon_skip_135064 | chr14 | 20316512:20316560:20318256:20318470:20325539:20325653 | 20318256:20318470 |
| exon_skip_186266 | chr14 | 20326716:20326793:20329174:20329373:20333254:20333279 | 20329174:20329373 |
| exon_skip_286368 | chr14 | 20316227:20316560:20317794:20317974:20325539:20325653 | 20317794:20317974 |
| exon_skip_37950 | chr14 | 20316227:20316560:20317795:20317974:20325539:20325653 | 20317795:20317974 |
| exon_skip_7768 | chr14 | 20313637:20313801:20315485:20315618:20316227:20316265 | 20315485:20315618 |
| exon_skip_84309 | chr14 | 20316512:20316560:20317794:20317974:20325539:20325653 | 20317794:20317974 |
| exon_skip_86662 | chr14 | 20313468:20313801:20315781:20315850:20316227:20316265 | 20315781:20315850 |
| exon_skip_9953 | chr14 | 20316480:20316560:20317795:20317974:20325539:20325653 | 20317795:20317974 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for CCNB1IP1 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000437553 | 20317794 | 20317974 | 3UTR-3UTR |
| ENST00000398169 | 20317795 | 20317974 | 3UTR-3UTR |
| ENST00000398163 | 20318256 | 20318470 | 3UTR-3UTR |
| ENST00000358932 | 20329174 | 20329373 | 3UTR-3UTR |
| ENST00000437553 | 20329174 | 20329373 | 3UTR-3UTR |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000437553 | 20317794 | 20317974 | 3UTR-3UTR |
| ENST00000398169 | 20317795 | 20317974 | 3UTR-3UTR |
| ENST00000398163 | 20318256 | 20318470 | 3UTR-3UTR |
| ENST00000358932 | 20329174 | 20329373 | 3UTR-3UTR |
| ENST00000437553 | 20329174 | 20329373 | 3UTR-3UTR |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000437553 | 20317794 | 20317974 | 3UTR-3UTR |
| ENST00000398169 | 20317795 | 20317974 | 3UTR-3UTR |
| ENST00000398163 | 20318256 | 20318470 | 3UTR-3UTR |
| ENST00000358932 | 20329174 | 20329373 | 3UTR-3UTR |
| ENST00000437553 | 20329174 | 20329373 | 3UTR-3UTR |
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Infer the effects of exon skipping event on protein functional features for CCNB1IP1 |
p-ENSG00000100814_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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3'-UTR located exon skipping events that lost miRNA binding sites in CCNB1IP1 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6727-5p | chr14:20317919-20317926 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6727-5p | chr14:20317919-20317926 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-1976 | chr14:20318377-20318384 | 8mer-1a | chr14:20318364-20318384 | 149.00 | -24.39 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-670-5p | chr14:20317883-20317890 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-670-5p | chr14:20317883-20317890 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6747-3p | chr14:20318375-20318382 | 8mer-1a | chr14:20318364-20318384 | 149.00 | -24.39 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4701-5p | chr14:20318281-20318288 | 8mer-1a | chr14:20318268-20318288 | 151.00 | -23.20 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-3652 | chr14:20318440-20318447 | 8mer-1a | chr14:20318429-20318447 | 159.00 | -24.44 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-3612 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-3612 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-345-3p | chr14:20317882-20317889 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-345-3p | chr14:20317882-20317889 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6511b-5p | chr14:20318346-20318353 | 8mer-1a | chr14:20318339-20318360 | 169.00 | -28.63 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6775-5p | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6775-5p | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-744-3p | chr14:20318449-20318456 | 8mer-1a | chr14:20318442-20318462 | 140.00 | -13.02 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-4736 | chr14:20317937-20317944 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-4736 | chr14:20317937-20317944 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4430 | chr14:20318440-20318447 | 8mer-1a | chr14:20318429-20318447 | 159.00 | -24.44 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6811-5p | chr14:20318346-20318353 | 8mer-1a | chr14:20318339-20318360 | 169.00 | -28.63 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6812-3p | chr14:20318455-20318462 | 8mer-1a | chr14:20318442-20318462 | 140.00 | -13.02 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-650 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-650 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4638-5p | chr14:20318418-20318425 | 8mer-1a | chr14:20318418-20318441 | 156.00 | -15.22 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-588 | chr14:20318281-20318288 | 8mer-1a | chr14:20318268-20318288 | 151.00 | -23.20 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6840-3p | chr14:20317930-20317937 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6840-3p | chr14:20317930-20317937 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-5090 | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-5090 | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| Mayo | ENST00000398169 | 20317795 | 20317974 | hsa-miR-937-3p | chr14:20317813-20317820 | 8mer-1a | chr14:20317799-20317820 | 160.00 | -23.15 |
| Mayo | ENST00000437553 | 20317794 | 20317974 | hsa-miR-937-3p | chr14:20317813-20317820 | 8mer-1a | chr14:20317799-20317820 | 160.00 | -23.15 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-3152-5p | chr14:20318400-20318407 | 8mer-1a | chr14:20318394-20318416 | 166.00 | -20.86 |
| Mayo | ENST00000437553 | 20329174 | 20329373 | hsa-miR-181a-2-3p | chr14:20329353-20329360 | 8mer-1a | chr14:20329349-20329370 | 147.00 | -24.23 |
| Mayo | ENST00000398163 | 20318256 | 20318470 | hsa-miR-504-3p | chr14:20318436-20318443 | 8mer-1a | chr14:20318424-20318446 | 155.00 | -33.78 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6727-5p | chr14:20317919-20317926 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6727-5p | chr14:20317919-20317926 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-1976 | chr14:20318377-20318384 | 8mer-1a | chr14:20318364-20318384 | 149.00 | -24.39 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-670-5p | chr14:20317883-20317890 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-670-5p | chr14:20317883-20317890 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6747-3p | chr14:20318375-20318382 | 8mer-1a | chr14:20318364-20318384 | 149.00 | -24.39 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4701-5p | chr14:20318281-20318288 | 8mer-1a | chr14:20318268-20318288 | 151.00 | -23.20 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-3652 | chr14:20318440-20318447 | 8mer-1a | chr14:20318429-20318447 | 159.00 | -24.44 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-3612 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-3612 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-345-3p | chr14:20317882-20317889 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-345-3p | chr14:20317882-20317889 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6511b-5p | chr14:20318346-20318353 | 8mer-1a | chr14:20318339-20318360 | 169.00 | -28.63 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6775-5p | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6775-5p | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-744-3p | chr14:20318449-20318456 | 8mer-1a | chr14:20318442-20318462 | 140.00 | -13.02 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-4736 | chr14:20317937-20317944 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-4736 | chr14:20317937-20317944 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4430 | chr14:20318440-20318447 | 8mer-1a | chr14:20318429-20318447 | 159.00 | -24.44 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6811-5p | chr14:20318346-20318353 | 8mer-1a | chr14:20318339-20318360 | 169.00 | -28.63 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6812-3p | chr14:20318455-20318462 | 8mer-1a | chr14:20318442-20318462 | 140.00 | -13.02 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-650 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-650 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4638-5p | chr14:20318418-20318425 | 8mer-1a | chr14:20318418-20318441 | 156.00 | -15.22 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-588 | chr14:20318281-20318288 | 8mer-1a | chr14:20318268-20318288 | 151.00 | -23.20 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6840-3p | chr14:20317930-20317937 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6840-3p | chr14:20317930-20317937 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-5090 | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-5090 | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| MSBB | ENST00000398169 | 20317795 | 20317974 | hsa-miR-937-3p | chr14:20317813-20317820 | 8mer-1a | chr14:20317799-20317820 | 160.00 | -23.15 |
| MSBB | ENST00000437553 | 20317794 | 20317974 | hsa-miR-937-3p | chr14:20317813-20317820 | 8mer-1a | chr14:20317799-20317820 | 160.00 | -23.15 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-3152-5p | chr14:20318400-20318407 | 8mer-1a | chr14:20318394-20318416 | 166.00 | -20.86 |
| MSBB | ENST00000437553 | 20329174 | 20329373 | hsa-miR-181a-2-3p | chr14:20329353-20329360 | 8mer-1a | chr14:20329349-20329370 | 147.00 | -24.23 |
| MSBB | ENST00000398163 | 20318256 | 20318470 | hsa-miR-504-3p | chr14:20318436-20318443 | 8mer-1a | chr14:20318424-20318446 | 155.00 | -33.78 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6727-5p | chr14:20317919-20317926 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6727-5p | chr14:20317919-20317926 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-1976 | chr14:20318377-20318384 | 8mer-1a | chr14:20318364-20318384 | 149.00 | -24.39 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-670-5p | chr14:20317883-20317890 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-670-5p | chr14:20317883-20317890 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6747-3p | chr14:20318375-20318382 | 8mer-1a | chr14:20318364-20318384 | 149.00 | -24.39 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4701-5p | chr14:20318281-20318288 | 8mer-1a | chr14:20318268-20318288 | 151.00 | -23.20 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-3652 | chr14:20318440-20318447 | 8mer-1a | chr14:20318429-20318447 | 159.00 | -24.44 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-3612 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-3612 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-345-3p | chr14:20317882-20317889 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-345-3p | chr14:20317882-20317889 | 8mer-1a | chr14:20317880-20317902 | 149.00 | -22.52 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6511b-5p | chr14:20318346-20318353 | 8mer-1a | chr14:20318339-20318360 | 169.00 | -28.63 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6775-5p | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6775-5p | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-744-3p | chr14:20318449-20318456 | 8mer-1a | chr14:20318442-20318462 | 140.00 | -13.02 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-4736 | chr14:20317937-20317944 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-4736 | chr14:20317937-20317944 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4430 | chr14:20318440-20318447 | 8mer-1a | chr14:20318429-20318447 | 159.00 | -24.44 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6811-5p | chr14:20318346-20318353 | 8mer-1a | chr14:20318339-20318360 | 169.00 | -28.63 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-6812-3p | chr14:20318455-20318462 | 8mer-1a | chr14:20318442-20318462 | 140.00 | -13.02 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-650 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-650 | chr14:20317830-20317837 | 8mer-1a | chr14:20317819-20317839 | 153.00 | -23.13 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-4638-5p | chr14:20318418-20318425 | 8mer-1a | chr14:20318418-20318441 | 156.00 | -15.22 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-588 | chr14:20318281-20318288 | 8mer-1a | chr14:20318268-20318288 | 151.00 | -23.20 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-6840-3p | chr14:20317930-20317937 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-6840-3p | chr14:20317930-20317937 | 8mer-1a | chr14:20317922-20317947 | 159.00 | -29.68 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-5090 | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-5090 | chr14:20317918-20317925 | 8mer-1a | chr14:20317918-20317937 | 153.00 | -28.27 |
| ROSMAP | ENST00000398169 | 20317795 | 20317974 | hsa-miR-937-3p | chr14:20317813-20317820 | 8mer-1a | chr14:20317799-20317820 | 160.00 | -23.15 |
| ROSMAP | ENST00000437553 | 20317794 | 20317974 | hsa-miR-937-3p | chr14:20317813-20317820 | 8mer-1a | chr14:20317799-20317820 | 160.00 | -23.15 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-3152-5p | chr14:20318400-20318407 | 8mer-1a | chr14:20318394-20318416 | 166.00 | -20.86 |
| ROSMAP | ENST00000437553 | 20329174 | 20329373 | hsa-miR-181a-2-3p | chr14:20329353-20329360 | 8mer-1a | chr14:20329349-20329370 | 147.00 | -24.23 |
| ROSMAP | ENST00000398163 | 20318256 | 20318470 | hsa-miR-504-3p | chr14:20318436-20318443 | 8mer-1a | chr14:20318424-20318446 | 155.00 | -33.78 |
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SNVs in the skipped exons for CCNB1IP1 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for CCNB1IP1 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CCNB1IP1 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for CCNB1IP1 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
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RelatedDrugs for CCNB1IP1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CCNB1IP1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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