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Open reading frame (ORF) annotation in the exon skipping event | |
3'-UTR located exon skipping events lost miRNA binding sites | |
Splicing Quantitative Trait Loci (sQTLs) in the skipped exons | |
Gene summary for USP37 |
Gene summary |
Gene information | Gene symbol | USP37 | Gene ID | 57695 |
Gene name | ubiquitin specific peptidase 37 | |
Synonyms | - | |
Cytomap | 2q35 | |
Type of gene | protein-coding | |
Description | ubiquitin carboxyl-terminal hydrolase 37deubiquitinating enzyme 37tmp_locus_50ubiquitin specific protease 37ubiquitin thioesterase 37ubiquitin thiolesterase 37ubiquitin-specific-processing protease 37 | |
Modification date | 20200313 | |
UniProtAcc | ||
Context |
Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Gene | GO ID | GO term | PubMed ID |
USP37 | GO:0000082 | G1/S transition of mitotic cell cycle | 21596315 |
USP37 | GO:0016579 | protein deubiquitination | 14715245 |
USP37 | GO:0035871 | protein K11-linked deubiquitination | 21596315 |
USP37 | GO:0071108 | protein K48-linked deubiquitination | 21596315 |
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Gene structures and expression levels for USP37 |
Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Differentially expressed gene analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
CB | UP | ENST00000415516.5 | USP37-203:protein_coding:USP37 | 8.225705e+00 | 2.222503e+00 | 1.278324e-09 | 5.339585e-08 |
CB | UP | ENST00000454775.5 | USP37-205:protein_coding:USP37 | 8.089670e+00 | 1.088296e+00 | 3.192542e-06 | 4.027743e-05 |
CB | UP | ENST00000478329.1 | USP37-209:lncRNA:USP37 | 2.952172e+00 | 8.800182e-01 | 2.661929e-04 | 1.696059e-03 |
TC | UP | ENST00000415516.5 | USP37-203:protein_coding:USP37 | 4.914466e+00 | 1.013584e+00 | 5.773537e-05 | 1.045668e-03 |
Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for USP37 |
Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
All exon skipping events in AD cohorts. |
Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
exon_skip_107161 | chr2 | 218455580:218455718:218457092:218457161:218459790:218459905 | 218457092:218457161 |
exon_skip_110560 | chr2 | 218485664:218485743:218488304:218488421:218495760:218495950 | 218488304:218488421 |
exon_skip_120491 | chr2 | 218553553:218553724:218558498:218558677:218560820:218560883 | 218558498:218558677 |
exon_skip_133316 | chr2 | 218459790:218459905:218463306:218463366:218466010:218466176 | 218463306:218463366 |
exon_skip_161981 | chr2 | 218466133:218466176:218473190:218473246:218474630:218474885 | 218473190:218473246 |
exon_skip_163160 | chr2 | 218529956:218530040:218534609:218534706:218546221:218546298 | 218534609:218534706 |
exon_skip_173145 | chr2 | 218558498:218558677:218560820:218560883:218562673:218562813 | 218560820:218560883 |
exon_skip_211953 | chr2 | 218457092:218457161:218459790:218459905:218463306:218463366 | 218459790:218459905 |
exon_skip_257668 | chr2 | 218466133:218466176:218474630:218474885:218476840:218476958 | 218474630:218474885 |
exon_skip_28756 | chr2 | 218476943:218476981:218479650:218479715:218482070:218482234 | 218479650:218479715 |
exon_skip_73551 | chr2 | 218553553:218553724:218558498:218558717:218560820:218560883 | 218558498:218558717 |
exon_skip_83122 | chr2 | 218510007:218510140:218529956:218530040:218534609:218534706 | 218529956:218530040 |
Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
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Open reading frame (ORF) annotation in the exon skipping event for USP37 |
Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000258399 | 218558498 | 218558677 | 3UTR-3CDS |
ENST00000418019 | 218558498 | 218558677 | 3UTR-3CDS |
ENST00000454775 | 218558498 | 218558717 | 3UTR-3CDS |
ENST00000258399 | 218560820 | 218560883 | 3UTR-3UTR |
ENST00000258399 | 218457092 | 218457161 | Frame-shift |
ENST00000418019 | 218457092 | 218457161 | Frame-shift |
ENST00000454775 | 218457092 | 218457161 | Frame-shift |
ENST00000258399 | 218529956 | 218530040 | Frame-shift |
ENST00000418019 | 218529956 | 218530040 | Frame-shift |
ENST00000454775 | 218529956 | 218530040 | Frame-shift |
ENST00000258399 | 218534609 | 218534706 | Frame-shift |
ENST00000418019 | 218534609 | 218534706 | Frame-shift |
ENST00000454775 | 218534609 | 218534706 | Frame-shift |
ENST00000258399 | 218479650 | 218479715 | In-frame |
ENST00000418019 | 218479650 | 218479715 | In-frame |
ENST00000454775 | 218479650 | 218479715 | In-frame |
Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000258399 | 218560820 | 218560883 | 3UTR-3UTR |
ENST00000258399 | 218457092 | 218457161 | Frame-shift |
ENST00000418019 | 218457092 | 218457161 | Frame-shift |
ENST00000454775 | 218457092 | 218457161 | Frame-shift |
ENST00000258399 | 218529956 | 218530040 | Frame-shift |
ENST00000418019 | 218529956 | 218530040 | Frame-shift |
ENST00000454775 | 218529956 | 218530040 | Frame-shift |
ENST00000258399 | 218534609 | 218534706 | Frame-shift |
ENST00000418019 | 218534609 | 218534706 | Frame-shift |
ENST00000454775 | 218534609 | 218534706 | Frame-shift |
ENST00000258399 | 218479650 | 218479715 | In-frame |
ENST00000418019 | 218479650 | 218479715 | In-frame |
ENST00000454775 | 218479650 | 218479715 | In-frame |
Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000258399 | 218560820 | 218560883 | 3UTR-3UTR |
ENST00000258399 | 218457092 | 218457161 | Frame-shift |
ENST00000418019 | 218457092 | 218457161 | Frame-shift |
ENST00000454775 | 218457092 | 218457161 | Frame-shift |
ENST00000258399 | 218459790 | 218459905 | Frame-shift |
ENST00000418019 | 218459790 | 218459905 | Frame-shift |
ENST00000454775 | 218459790 | 218459905 | Frame-shift |
ENST00000258399 | 218463306 | 218463366 | Frame-shift |
ENST00000418019 | 218463306 | 218463366 | Frame-shift |
ENST00000454775 | 218463306 | 218463366 | Frame-shift |
ENST00000258399 | 218474630 | 218474885 | Frame-shift |
ENST00000418019 | 218474630 | 218474885 | Frame-shift |
ENST00000454775 | 218474630 | 218474885 | Frame-shift |
ENST00000258399 | 218488304 | 218488421 | Frame-shift |
ENST00000418019 | 218488304 | 218488421 | Frame-shift |
ENST00000454775 | 218488304 | 218488421 | Frame-shift |
ENST00000258399 | 218529956 | 218530040 | Frame-shift |
ENST00000418019 | 218529956 | 218530040 | Frame-shift |
ENST00000454775 | 218529956 | 218530040 | Frame-shift |
ENST00000258399 | 218534609 | 218534706 | Frame-shift |
ENST00000418019 | 218534609 | 218534706 | Frame-shift |
ENST00000454775 | 218534609 | 218534706 | Frame-shift |
ENST00000258399 | 218479650 | 218479715 | In-frame |
ENST00000418019 | 218479650 | 218479715 | In-frame |
ENST00000454775 | 218479650 | 218479715 | In-frame |
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Infer the effects of exon skipping event on protein functional features for USP37 |
p-ENSG00000135913_img4.png |
Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000258399 | 8049 | 979 | 218479650 | 218479715 | 2249 | 2313 | 612 | 633 |
ENST00000418019 | 3370 | 979 | 218479650 | 218479715 | 2134 | 2198 | 612 | 633 |
ENST00000454775 | 5036 | 979 | 218479650 | 218479715 | 2253 | 2317 | 612 | 633 |
Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000258399 | 8049 | 979 | 218479650 | 218479715 | 2249 | 2313 | 612 | 633 |
ENST00000418019 | 3370 | 979 | 218479650 | 218479715 | 2134 | 2198 | 612 | 633 |
ENST00000454775 | 5036 | 979 | 218479650 | 218479715 | 2253 | 2317 | 612 | 633 |
Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
ENST00000258399 | 8049 | 979 | 218479650 | 218479715 | 2249 | 2313 | 612 | 633 |
ENST00000418019 | 3370 | 979 | 218479650 | 218479715 | 2134 | 2198 | 612 | 633 |
ENST00000454775 | 5036 | 979 | 218479650 | 218479715 | 2253 | 2317 | 612 | 633 |
Lost protein functional features of individual exon skipping events in ROSMAP. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Lost protein functional features of individual exon skipping events in MSBB. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Lost protein functional features of individual exon skipping events in Mayo. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 612 | 634 | Alternative sequence | ID=VSP_041741;Note=In isoform 2. ISRPLKASQMVNSCITSPSTPSK->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 1 | 979 | Chain | ID=PRO_0000080667;Note=Ubiquitin carboxyl-terminal hydrolase 37 |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 341 | 951 | Domain | Note=USP |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Modified residue | Note=Phosphoserine%3B by CDK2;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:27296872;Dbxref=PMID:21596315,PMID:27296872 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
Q86T82 | 612 | 633 | 628 | 628 | Mutagenesis | Note=Abolishes phosphorylation by CDK2%2C leading to lower deubiquitinase activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21596315;Dbxref=PMID:21596315 |
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3'-UTR located exon skipping events that lost miRNA binding sites in USP37 |
3'-UTR exon skipping evnets lost miRNA binding. |
Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
Mayo | ENST00000258399 | 218560820 | 218560883 | hsa-miR-5590-5p | chr2:218560872-218560879 | 8mer-1a | chr2:218560859-218560879 | 156.00 | -16.44 |
Mayo | ENST00000258399 | 218560820 | 218560883 | hsa-miR-4776-3p | chr2:218560873-218560880 | 8mer-1a | chr2:218560857-218560880 | 148.00 | -13.66 |
MSBB | ENST00000258399 | 218560820 | 218560883 | hsa-miR-5590-5p | chr2:218560872-218560879 | 8mer-1a | chr2:218560859-218560879 | 156.00 | -16.44 |
MSBB | ENST00000258399 | 218560820 | 218560883 | hsa-miR-4776-3p | chr2:218560873-218560880 | 8mer-1a | chr2:218560857-218560880 | 148.00 | -13.66 |
ROSMAP | ENST00000258399 | 218560820 | 218560883 | hsa-miR-5590-5p | chr2:218560872-218560879 | 8mer-1a | chr2:218560859-218560879 | 156.00 | -16.44 |
ROSMAP | ENST00000258399 | 218560820 | 218560883 | hsa-miR-4776-3p | chr2:218560873-218560880 | 8mer-1a | chr2:218560857-218560880 | 148.00 | -13.66 |
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SNVs in the skipped exons for USP37 |
- Differential PSIs between mutated versus non-mutated samples. |
- Depth of Coverage in the skipped exon of the mutated samples. |
- Sashimi plot in the skipped exon of the mutated samples. |
- Non-synonymous mutations located in the skipped exons. |
Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
- Non-synonymous mutations located in the skipped exons in CCLE. |
Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for USP37 |
Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for USP37 |
sQTL information located at the skipped exons. |
Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for USP37 |
Correlated RBP and related information. |
Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
HCC | ZNF326 | exon_skip_28756 | -4.494148e-01 | 1.243190e-13 |
IFG | SRSF4 | exon_skip_163160 | -4.291324e-01 | 4.101643e-02 |
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RelatedDrugs for USP37 |
Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for USP37 |
Diseases associated with this gene. (DisGeNet 4.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |