ExonSkipAD: functional annotation of exon skipping event in human

Gene summary for MAPK10

Gene summary

Gene information	Gene symbol	MAPK10
	Gene ID	5602
	Gene name	mitogen-activated protein kinase 10
	Synonyms	JNK3\|JNK3A\|PRKM10\|SAPK1b\|p493F12\|p54bSAPK
	Cytomap	4q21.3
	Type of gene	protein-coding
	Description	mitogen-activated protein kinase 10JNK3 alpha protein kinaseMAP kinase 10MAP kinase p49 3F12c-Jun N-terminal kinase 3stress activated protein kinase betastress-activated protein kinase 1bstress-activated protein kinase JNK3
	Modification date	20200313
	UniProtAcc	A0A1P0B7D2, A0A1W2PNF5, A0A1W2PPM4, A0A1W2PPW1, A0A1W2PPZ3, A0A1W2PQ03, A0A1W2PQX4, A0A1W2PRF2, A0A1W2PRG9, A0A1W2PRZ2, A0A286YEN5, A0A286YEQ0, A0A286YEQ7, A0A286YES0, A0A286YES8, A0A286YES9, A0A286YEV3, A0A286YEV5, A0A286YEV8, A0A286YEW4, A0A286YEW9, A0A286YEX7, A0A286YEY0, A0A286YEY2, A0A286YEZ1, A0A286YF02, A0A286YF04, A0A286YF19, A0A286YF35, A0A286YF43, A0A286YF53, A0A286YF62, A0A286YF80, A0A286YF83, A0A286YF85, A0A286YF95, A0A286YF97, A0A286YFA3, A0A286YFA6, A0A286YFA7, A0A286YFB6, A0A286YFB7, A0A286YFC0, A0A286YFC3, A0A286YFD7, A0A286YFD9, A0A286YFE2, A0A286YFE9, A0A286YFH4, A0A286YFI3, A0A286YFJ0, A0A286YFJ4, A0A286YFJ6, A0A286YFK3, A0A286YFM6, A0A286YFN2, A8MPV1, D6R9C1, D6RAJ0, D6RAU3, D6RBH2, D6RC26, D6RCB1, D6RDG1, D6RFX8, D6RFZ7, D6RJF9, F8W9R5, I6L9F3, P53779, Q499Y8,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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Gene structures and expression levels for MAPK10

Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

ENSG00000109339

Differentially expressed gene analysis across multiple brain tissues between AD and control.

Tissue type

DEG direction

Base mean exp.

log2FC(AD/control)

P-value

Adj. p-value

Differentially expressed isoform analysis across multiple brain tissues between AD and control.

Tissue type	DEG direction	ENST	Transcript info.	Base mean exp.	log2FC(AD/control)	P-value	Adjc. p-value
PCC	UP	ENST00000641824.1	MAPK10-354:lncRNA:MAPK10	2.317669e+01	8.238408e-01	1.009565e-03	2.575803e-02
HCC	UP	ENST00000641862.1	MAPK10-360:protein_coding:MAPK10	3.199892e+00	4.026253e+00	7.248390e-05	5.672169e-03
PG	DOWN	ENST00000641462.2	MAPK10-319:protein_coding:MAPK10	1.045113e+03	-8.098382e-01	1.957013e-04	4.487883e-03
PG	DOWN	ENST00000641595.1	MAPK10-331:nonsense_mediated_decay:MAPK10	1.140394e+00	-4.208950e+00	4.989166e-03	4.565210e-02
IFG	DOWN	ENST00000642032.1	MAPK10-382:protein_coding:MAPK10	7.935738e+00	-2.346726e+01	2.519120e-17	3.787560e-13
CB	DOWN	ENST00000641824.1	MAPK10-354:lncRNA:MAPK10	1.552149e+02	-1.451106e+00	7.173048e-07	1.129489e-05
CB	DOWN	ENST00000642136.1	MAPK10-392:retained_intron:MAPK10	5.699972e+01	-2.122869e+00	1.766280e-05	1.706374e-04
CB	UP	ENST00000449047.7	MAPK10-209:protein_coding:MAPK10	4.336580e+00	3.857189e+00	3.810355e-03	1.571436e-02
CB	DOWN	ENST00000641120.1	MAPK10-273:protein_coding:MAPK10	1.922849e+01	-3.180231e+00	5.222263e-03	2.039577e-02
CB	UP	ENST00000641997.1	MAPK10-375:nonsense_mediated_decay:MAPK10	3.386053e+01	1.144108e+00	7.565053e-03	2.765624e-02
TC	UP	ENST00000639989.2	MAPK10-244:protein_coding:MAPK10	7.284905e+00	1.229235e+00	1.264105e-08	1.095685e-06
TC	UP	ENST00000641050.1	MAPK10-260:protein_coding:MAPK10	9.085286e+01	1.931701e+00	2.738559e-04	3.586303e-03
TC	UP	ENST00000641657.1	MAPK10-340:protein_coding:MAPK10	6.174617e+00	5.289015e+00	5.151513e-04	5.888495e-03
TC	DOWN	ENST00000641208.1	MAPK10-285:protein_coding:MAPK10	4.034352e+01	-4.580348e+00	8.226357e-04	8.490282e-03
TC	UP	ENST00000361569.8	MAPK10-203:protein_coding:MAPK10	4.098958e+01	1.366433e+00	8.893695e-04	9.026921e-03
TC	DOWN	ENST00000641824.1	MAPK10-354:lncRNA:MAPK10	3.636146e+02	-8.426805e-01	9.074552e-04	9.171213e-03
TC	UP	ENST00000513186.7	MAPK10-228:protein_coding:MAPK10	1.846361e+01	9.340151e-01	3.690496e-03	2.664004e-02
TC	DOWN	ENST00000642060.1	MAPK10-388:nonsense_mediated_decay:MAPK10	4.106307e+01	-4.258405e+00	6.007043e-03	3.839528e-02
TC	UP	ENST00000641391.1	MAPK10-311:protein_coding:MAPK10	4.612171e+01	9.184971e-01	6.586735e-03	4.111845e-02

Landscape of isoform expressions across multiple brain tissues between AD and control.

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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for MAPK10

Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap).

All exon skipping events in AD cohorts.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon
exon_skip_101657	chr4	86194336:86194407:86354530:86354644:86359658:86360058	86354530:86354644
exon_skip_103776	chr4	86354530:86354644:86370714:86370867:86384100:86384229	86370714:86370867
exon_skip_108443	chr4	86098421:86098448:86101052:86101217:86101894:86101922	86101052:86101217
exon_skip_110970	chr4	86107223:86107352:86151991:86152144:86152463:86152629	86151991:86152144
exon_skip_124135	chr4	86194394:86194407:86335076:86335156:86354530:86354644	86335076:86335156
exon_skip_131053	chr4	86101194:86101217:86101894:86102032:86103186:86103244	86101894:86102032
exon_skip_132962	chr4	86151991:86152144:86152463:86152629:86159298:86159466	86152463:86152629
exon_skip_144126	chr4	86107223:86107352:86194309:86194407:86354530:86354644	86194309:86194407
exon_skip_148037	chr4	86194336:86194407:86354530:86354644:86399747:86399806	86354530:86354644
exon_skip_148042	chr4	86107343:86107352:86151991:86152144:86152463:86152629	86151991:86152144
exon_skip_156703	chr4	86107343:86107352:86152463:86152629:86159298:86159334	86152463:86152629
exon_skip_157191	chr4	86101894:86102032:86102271:86102466:86103186:86103244	86102271:86102466
exon_skip_159590	chr4	86095602:86095716:86098421:86098448:86101052:86101217	86098421:86098448
exon_skip_160654	chr4	86107343:86107352:86151991:86152196:86159298:86159467	86151991:86152196
exon_skip_16071	chr4	86194336:86194407:86335076:86335156:86354530:86354639	86335076:86335156
exon_skip_161537	chr4	86321844:86322029:86335076:86335156:86354530:86354639	86335076:86335156
exon_skip_163705	chr4	86031368:86031431:86040873:86040984:86064266:86064386	86040873:86040984
exon_skip_163736	chr4	86354530:86354644:86429678:86429805:86453030:86453212	86429678:86429805
exon_skip_169805	chr4	86107223:86107352:86151991:86152196:86152463:86152629	86151991:86152196
exon_skip_175169	chr4	86354530:86354644:86453030:86453181:86593910:86594074	86453030:86453181
exon_skip_179900	chr4	86194336:86194407:86354530:86354644:86453030:86453181	86354530:86354644
exon_skip_18729	chr4	86194336:86194407:86354530:86354644:86429678:86429805	86354530:86354644
exon_skip_187978	chr4	86067936:86067955:86098524:86098595:86101052:86101217	86098524:86098595
exon_skip_195292	chr4	86159361:86159467:86194319:86194407:86354530:86354639	86194319:86194407
exon_skip_19679	chr4	86067886:86067955:86089206:86089277:86101894:86101922	86089206:86089277
exon_skip_197015	chr4	86194336:86194407:86340339:86340423:86354530:86354639	86340339:86340423
exon_skip_199066	chr4	86031368:86031431:86040873:86040984:86064266:86064390	86040873:86040984
exon_skip_20046	chr4	86031368:86031431:86107223:86107352:86159298:86159334	86107223:86107352
exon_skip_202830	chr4	86107223:86107352:86194336:86194407:86354530:86354644	86194336:86194407
exon_skip_207835	chr4	86089206:86089277:86101052:86101217:86101894:86101922	86101052:86101217
exon_skip_212280	chr4	86159361:86159467:86194309:86194335:86354530:86354644	86194309:86194335
exon_skip_212512	chr4	86067886:86067955:86098524:86098595:86101052:86101217	86098524:86098595
exon_skip_220915	chr4	86159361:86159467:86194309:86194407:86354530:86354639	86194309:86194407
exon_skip_225071	chr4	86151991:86152196:86152463:86152629:86159298:86159467	86152463:86152629
exon_skip_241584	chr4	86159361:86159467:86194309:86194335:86354530:86354639	86194309:86194335
exon_skip_241828	chr4	86107343:86107352:86159298:86159467:86194336:86194407	86159298:86159467
exon_skip_24276	chr4	86067936:86067955:86089206:86089277:86101052:86101217	86089206:86089277
exon_skip_246200	chr4	86354530:86354644:86370714:86370867:86384100:86384236	86370714:86370867
exon_skip_247053	chr4	86194336:86194407:86277050:86277223:86354530:86354644	86277050:86277223
exon_skip_248481	chr4	86098524:86098595:86101052:86101217:86101894:86101922	86101052:86101217
exon_skip_254211	chr4	86107223:86107352:86194309:86194407:86354530:86354639	86194309:86194407
exon_skip_261036	chr4	86151991:86152144:86152463:86152629:86159298:86159334	86152463:86152629
exon_skip_262716	chr4	86067886:86067955:86098524:86099285:86101052:86101217	86098524:86099285
exon_skip_264033	chr4	86107223:86107352:86159298:86159467:86194309:86194407	86159298:86159467
exon_skip_264581	chr4	86194336:86194407:86335076:86335156:86354530:86354644	86335076:86335156
exon_skip_264856	chr4	86194394:86194407:86335076:86335156:86354530:86354639	86335076:86335156
exon_skip_268040	chr4	86107343:86107352:86159298:86159467:86194309:86194335	86159298:86159467
exon_skip_275095	chr4	86354530:86354644:86356462:86356519:86359658:86360028	86356462:86356519
exon_skip_279324	chr4	86067886:86067955:86101052:86101217:86101894:86101922	86101052:86101217
exon_skip_279352	chr4	86067886:86067955:86089206:86089277:86101052:86101217	86089206:86089277
exon_skip_280398	chr4	86354530:86354644:86370714:86370867:86453030:86453181	86370714:86370867
exon_skip_280803	chr4	86107223:86107352:86159298:86159467:86354530:86354639	86159298:86159467
exon_skip_284362	chr4	86194336:86194407:86277050:86277223:86354530:86354639	86277050:86277223
exon_skip_286132	chr4	86107343:86107352:86151991:86152196:86152463:86152629	86151991:86152196
exon_skip_28802	chr4	86067936:86067955:86098524:86099285:86101052:86101217	86098524:86099285
exon_skip_291105	chr4	86194336:86194407:86321844:86322029:86335076:86335156	86321844:86322029
exon_skip_292106	chr4	86151991:86152196:86152463:86152629:86159298:86159334	86152463:86152629
exon_skip_296592	chr4	86102013:86102032:86103186:86103244:86107223:86107243	86103186:86103244
exon_skip_38957	chr4	86107343:86107352:86151991:86152144:86159298:86159334	86151991:86152144
exon_skip_39016	chr4	86159361:86159467:86194336:86194407:86354530:86354644	86194336:86194407
exon_skip_41362	chr4	86089206:86089277:86090305:86090437:86101052:86101217	86090305:86090437
exon_skip_45610	chr4	86354530:86354644:86359658:86359844:86360063:86360224	86359658:86359844
exon_skip_47578	chr4	86095602:86095716:86098421:86098595:86101052:86101217	86098421:86098595
exon_skip_49862	chr4	86107343:86107352:86151991:86152144:86159298:86159466	86151991:86152144
exon_skip_5141	chr4	86107223:86107352:86152463:86152629:86159298:86159334	86152463:86152629
exon_skip_55382	chr4	86194336:86194407:86340339:86340423:86354530:86354582	86340339:86340423
exon_skip_55605	chr4	86107223:86107352:86194336:86194407:86354530:86354639	86194336:86194407
exon_skip_6087	chr4	86107223:86107352:86159298:86159467:86354530:86354644	86159298:86159467
exon_skip_61144	chr4	86194394:86194407:86321844:86322029:86335076:86335156	86321844:86322029
exon_skip_62084	chr4	86089206:86089277:86101052:86101217:86101894:86102032	86101052:86101217
exon_skip_69624	chr4	86067886:86067955:86098524:86101217:86101894:86101922	86098524:86101217
exon_skip_75622	chr4	86159361:86159467:86194319:86194407:86354530:86354644	86194319:86194407
exon_skip_76892	chr4	86321844:86322029:86335076:86335156:86354530:86354644	86335076:86335156
exon_skip_81739	chr4	86194336:86194407:86340339:86340423:86354530:86354644	86340339:86340423
exon_skip_84232	chr4	86107343:86107352:86151991:86152196:86159298:86159334	86151991:86152196
exon_skip_90395	chr4	86159361:86159467:86194309:86194407:86354530:86354644	86194309:86194407
exon_skip_91698	chr4	86159361:86159467:86194336:86194407:86354530:86354639	86194336:86194407
exon_skip_93943	chr4	86194394:86194407:86321844:86322029:86354530:86354639	86321844:86322029
exon_skip_94548	chr4	86102013:86102032:86107223:86107352:86159298:86159334	86107223:86107352
exon_skip_99424	chr4	86194394:86194407:86321844:86322029:86354530:86354644	86321844:86322029

Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control.

Exon skipping information

Tissue type

Avg(PSIs) in AD

Avg(PSIs) in control

Difference (PSI)

Adj. p-value

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Open reading frame (ORF) annotation in the exon skipping event for MAPK10

Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000515650	86194336	86194407	3UTR-3CDS
ENST00000638313	86194336	86194407	3UTR-3CDS
ENST00000641051	86194336	86194407	3UTR-3CDS
ENST00000641066	86194336	86194407	3UTR-3CDS
ENST00000641157	86194336	86194407	3UTR-3CDS
ENST00000641462	86194336	86194407	3UTR-3CDS
ENST00000641902	86194336	86194407	3UTR-3CDS
ENST00000641952	86194336	86194407	3UTR-3CDS
ENST00000641983	86194336	86194407	3UTR-3CDS
ENST00000641341	86321844	86322029	3UTR-3UTR
ENST00000641647	86321844	86322029	3UTR-3UTR
ENST00000641823	86335076	86335156	3UTR-3UTR
ENST00000641207	86340339	86340423	3UTR-3UTR
ENST00000641051	86354530	86354644	3UTR-3UTR
ENST00000641157	86354530	86354644	3UTR-3UTR
ENST00000641462	86354530	86354644	3UTR-3UTR
ENST00000641902	86354530	86354644	3UTR-3UTR
ENST00000641952	86354530	86354644	3UTR-3UTR
ENST00000641051	86453030	86453181	3UTR-3UTR
ENST00000515400	86101052	86101217	Frame-shift
ENST00000515650	86101052	86101217	Frame-shift
ENST00000638313	86101052	86101217	Frame-shift
ENST00000641051	86101052	86101217	Frame-shift
ENST00000641066	86101052	86101217	Frame-shift
ENST00000641157	86101052	86101217	Frame-shift
ENST00000641207	86101052	86101217	Frame-shift
ENST00000641341	86101052	86101217	Frame-shift
ENST00000641462	86101052	86101217	Frame-shift
ENST00000641647	86101052	86101217	Frame-shift
ENST00000641823	86101052	86101217	Frame-shift
ENST00000641902	86101052	86101217	Frame-shift
ENST00000641952	86101052	86101217	Frame-shift
ENST00000641983	86101052	86101217	Frame-shift
ENST00000515400	86103186	86103244	Frame-shift
ENST00000515650	86103186	86103244	Frame-shift
ENST00000638313	86103186	86103244	Frame-shift
ENST00000641051	86103186	86103244	Frame-shift
ENST00000641066	86103186	86103244	Frame-shift
ENST00000641157	86103186	86103244	Frame-shift
ENST00000641207	86103186	86103244	Frame-shift
ENST00000641341	86103186	86103244	Frame-shift
ENST00000641462	86103186	86103244	Frame-shift
ENST00000641647	86103186	86103244	Frame-shift
ENST00000641823	86103186	86103244	Frame-shift
ENST00000641902	86103186	86103244	Frame-shift
ENST00000641952	86103186	86103244	Frame-shift
ENST00000641983	86103186	86103244	Frame-shift
ENST00000515400	86159298	86159467	Frame-shift
ENST00000515650	86159298	86159467	Frame-shift
ENST00000638313	86159298	86159467	Frame-shift
ENST00000641051	86159298	86159467	Frame-shift
ENST00000641066	86159298	86159467	Frame-shift
ENST00000641157	86159298	86159467	Frame-shift
ENST00000641207	86159298	86159467	Frame-shift
ENST00000641341	86159298	86159467	Frame-shift
ENST00000641462	86159298	86159467	Frame-shift
ENST00000641647	86159298	86159467	Frame-shift
ENST00000641823	86159298	86159467	Frame-shift
ENST00000641902	86159298	86159467	Frame-shift
ENST00000641952	86159298	86159467	Frame-shift
ENST00000641983	86159298	86159467	Frame-shift
ENST00000515400	86098524	86098595	In-frame
ENST00000515650	86098524	86098595	In-frame
ENST00000638313	86098524	86098595	In-frame
ENST00000641051	86098524	86098595	In-frame
ENST00000641066	86098524	86098595	In-frame
ENST00000641157	86098524	86098595	In-frame
ENST00000641207	86098524	86098595	In-frame
ENST00000641341	86098524	86098595	In-frame
ENST00000641462	86098524	86098595	In-frame
ENST00000641647	86098524	86098595	In-frame
ENST00000641823	86098524	86098595	In-frame
ENST00000641902	86098524	86098595	In-frame
ENST00000641952	86098524	86098595	In-frame
ENST00000641983	86098524	86098595	In-frame

Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000515650	86194336	86194407	3UTR-3CDS
ENST00000638313	86194336	86194407	3UTR-3CDS
ENST00000641051	86194336	86194407	3UTR-3CDS
ENST00000641066	86194336	86194407	3UTR-3CDS
ENST00000641157	86194336	86194407	3UTR-3CDS
ENST00000641462	86194336	86194407	3UTR-3CDS
ENST00000641902	86194336	86194407	3UTR-3CDS
ENST00000641952	86194336	86194407	3UTR-3CDS
ENST00000641983	86194336	86194407	3UTR-3CDS
ENST00000641341	86321844	86322029	3UTR-3UTR
ENST00000641647	86321844	86322029	3UTR-3UTR
ENST00000641823	86335076	86335156	3UTR-3UTR
ENST00000641207	86340339	86340423	3UTR-3UTR
ENST00000641051	86354530	86354644	3UTR-3UTR
ENST00000641462	86354530	86354644	3UTR-3UTR
ENST00000641952	86354530	86354644	3UTR-3UTR
ENST00000641051	86453030	86453181	3UTR-3UTR
ENST00000515400	86101894	86102032	Frame-shift
ENST00000515650	86101894	86102032	Frame-shift
ENST00000638313	86101894	86102032	Frame-shift
ENST00000641051	86101894	86102032	Frame-shift
ENST00000641066	86101894	86102032	Frame-shift
ENST00000641157	86101894	86102032	Frame-shift
ENST00000641207	86101894	86102032	Frame-shift
ENST00000641341	86101894	86102032	Frame-shift
ENST00000641462	86101894	86102032	Frame-shift
ENST00000641647	86101894	86102032	Frame-shift
ENST00000641823	86101894	86102032	Frame-shift
ENST00000641902	86101894	86102032	Frame-shift
ENST00000641952	86101894	86102032	Frame-shift
ENST00000641983	86101894	86102032	Frame-shift
ENST00000515400	86103186	86103244	Frame-shift
ENST00000515650	86103186	86103244	Frame-shift
ENST00000638313	86103186	86103244	Frame-shift
ENST00000641051	86103186	86103244	Frame-shift
ENST00000641066	86103186	86103244	Frame-shift
ENST00000641157	86103186	86103244	Frame-shift
ENST00000641207	86103186	86103244	Frame-shift
ENST00000641341	86103186	86103244	Frame-shift
ENST00000641462	86103186	86103244	Frame-shift
ENST00000641647	86103186	86103244	Frame-shift
ENST00000641823	86103186	86103244	Frame-shift
ENST00000641902	86103186	86103244	Frame-shift
ENST00000641952	86103186	86103244	Frame-shift
ENST00000641983	86103186	86103244	Frame-shift
ENST00000515400	86159298	86159467	Frame-shift
ENST00000515650	86159298	86159467	Frame-shift
ENST00000638313	86159298	86159467	Frame-shift
ENST00000641051	86159298	86159467	Frame-shift
ENST00000641066	86159298	86159467	Frame-shift
ENST00000641157	86159298	86159467	Frame-shift
ENST00000641207	86159298	86159467	Frame-shift
ENST00000641341	86159298	86159467	Frame-shift
ENST00000641462	86159298	86159467	Frame-shift
ENST00000641647	86159298	86159467	Frame-shift
ENST00000641823	86159298	86159467	Frame-shift
ENST00000641902	86159298	86159467	Frame-shift
ENST00000641952	86159298	86159467	Frame-shift
ENST00000641983	86159298	86159467	Frame-shift
ENST00000515400	86098524	86098595	In-frame
ENST00000515650	86098524	86098595	In-frame
ENST00000638313	86098524	86098595	In-frame
ENST00000641051	86098524	86098595	In-frame
ENST00000641066	86098524	86098595	In-frame
ENST00000641157	86098524	86098595	In-frame
ENST00000641207	86098524	86098595	In-frame
ENST00000641341	86098524	86098595	In-frame
ENST00000641462	86098524	86098595	In-frame
ENST00000641647	86098524	86098595	In-frame
ENST00000641823	86098524	86098595	In-frame
ENST00000641902	86098524	86098595	In-frame
ENST00000641952	86098524	86098595	In-frame
ENST00000641983	86098524	86098595	In-frame

Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000515650	86194336	86194407	3UTR-3CDS
ENST00000638313	86194336	86194407	3UTR-3CDS
ENST00000641051	86194336	86194407	3UTR-3CDS
ENST00000641066	86194336	86194407	3UTR-3CDS
ENST00000641157	86194336	86194407	3UTR-3CDS
ENST00000641462	86194336	86194407	3UTR-3CDS
ENST00000641902	86194336	86194407	3UTR-3CDS
ENST00000641952	86194336	86194407	3UTR-3CDS
ENST00000641983	86194336	86194407	3UTR-3CDS
ENST00000641341	86321844	86322029	3UTR-3UTR
ENST00000641647	86321844	86322029	3UTR-3UTR
ENST00000641823	86335076	86335156	3UTR-3UTR
ENST00000641207	86340339	86340423	3UTR-3UTR
ENST00000641051	86354530	86354644	3UTR-3UTR
ENST00000641462	86354530	86354644	3UTR-3UTR
ENST00000641952	86354530	86354644	3UTR-3UTR
ENST00000641051	86453030	86453181	3UTR-3UTR
ENST00000515400	86101052	86101217	Frame-shift
ENST00000515650	86101052	86101217	Frame-shift
ENST00000638313	86101052	86101217	Frame-shift
ENST00000641051	86101052	86101217	Frame-shift
ENST00000641066	86101052	86101217	Frame-shift
ENST00000641157	86101052	86101217	Frame-shift
ENST00000641207	86101052	86101217	Frame-shift
ENST00000641341	86101052	86101217	Frame-shift
ENST00000641462	86101052	86101217	Frame-shift
ENST00000641647	86101052	86101217	Frame-shift
ENST00000641823	86101052	86101217	Frame-shift
ENST00000641902	86101052	86101217	Frame-shift
ENST00000641952	86101052	86101217	Frame-shift
ENST00000641983	86101052	86101217	Frame-shift
ENST00000515400	86103186	86103244	Frame-shift
ENST00000515650	86103186	86103244	Frame-shift
ENST00000638313	86103186	86103244	Frame-shift
ENST00000641051	86103186	86103244	Frame-shift
ENST00000641066	86103186	86103244	Frame-shift
ENST00000641157	86103186	86103244	Frame-shift
ENST00000641207	86103186	86103244	Frame-shift
ENST00000641341	86103186	86103244	Frame-shift
ENST00000641462	86103186	86103244	Frame-shift
ENST00000641647	86103186	86103244	Frame-shift
ENST00000641823	86103186	86103244	Frame-shift
ENST00000641902	86103186	86103244	Frame-shift
ENST00000641952	86103186	86103244	Frame-shift
ENST00000641983	86103186	86103244	Frame-shift
ENST00000515400	86159298	86159467	Frame-shift
ENST00000515650	86159298	86159467	Frame-shift
ENST00000638313	86159298	86159467	Frame-shift
ENST00000641051	86159298	86159467	Frame-shift
ENST00000641066	86159298	86159467	Frame-shift
ENST00000641157	86159298	86159467	Frame-shift
ENST00000641207	86159298	86159467	Frame-shift
ENST00000641341	86159298	86159467	Frame-shift
ENST00000641462	86159298	86159467	Frame-shift
ENST00000641647	86159298	86159467	Frame-shift
ENST00000641823	86159298	86159467	Frame-shift
ENST00000641902	86159298	86159467	Frame-shift
ENST00000641952	86159298	86159467	Frame-shift
ENST00000641983	86159298	86159467	Frame-shift
ENST00000515400	86098524	86098595	In-frame
ENST00000515650	86098524	86098595	In-frame
ENST00000638313	86098524	86098595	In-frame
ENST00000641051	86098524	86098595	In-frame
ENST00000641066	86098524	86098595	In-frame
ENST00000641157	86098524	86098595	In-frame
ENST00000641207	86098524	86098595	In-frame
ENST00000641341	86098524	86098595	In-frame
ENST00000641462	86098524	86098595	In-frame
ENST00000641647	86098524	86098595	In-frame
ENST00000641823	86098524	86098595	In-frame
ENST00000641902	86098524	86098595	In-frame
ENST00000641952	86098524	86098595	In-frame
ENST00000641983	86098524	86098595	In-frame

Top

Infer the effects of exon skipping event on protein functional features for MAPK10

p-ENSG00000109339_img4.png
boxplot

Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000515400	2093	464	86098524	86098595	1054	1124	243	267
ENST00000515650	2411	464	86098524	86098595	1679	1749	243	267
ENST00000638313	3988	464	86098524	86098595	1110	1180	243	267
ENST00000641051	5755	464	86098524	86098595	1720	1790	243	267
ENST00000641066	6572	464	86098524	86098595	1154	1224	243	267
ENST00000641157	2466	464	86098524	86098595	1091	1161	243	267
ENST00000641207	2763	464	86098524	86098595	1342	1412	243	267
ENST00000641341	4001	464	86098524	86098595	1123	1193	243	267
ENST00000641462	6713	464	86098524	86098595	1292	1362	243	267
ENST00000641647	3379	464	86098524	86098595	1439	1509	243	267
ENST00000641823	2749	464	86098524	86098595	1327	1397	243	267
ENST00000641902	3842	464	86098524	86098595	1086	1156	243	267
ENST00000641952	5226	464	86098524	86098595	1197	1267	243	267
ENST00000641983	6789	464	86098524	86098595	1358	1428	243	267

Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000515400	2093	464	86098524	86098595	1054	1124	243	267
ENST00000515650	2411	464	86098524	86098595	1679	1749	243	267
ENST00000638313	3988	464	86098524	86098595	1110	1180	243	267
ENST00000641051	5755	464	86098524	86098595	1720	1790	243	267
ENST00000641066	6572	464	86098524	86098595	1154	1224	243	267
ENST00000641157	2466	464	86098524	86098595	1091	1161	243	267
ENST00000641207	2763	464	86098524	86098595	1342	1412	243	267
ENST00000641341	4001	464	86098524	86098595	1123	1193	243	267
ENST00000641462	6713	464	86098524	86098595	1292	1362	243	267
ENST00000641647	3379	464	86098524	86098595	1439	1509	243	267
ENST00000641823	2749	464	86098524	86098595	1327	1397	243	267
ENST00000641902	3842	464	86098524	86098595	1086	1156	243	267
ENST00000641952	5226	464	86098524	86098595	1197	1267	243	267
ENST00000641983	6789	464	86098524	86098595	1358	1428	243	267

Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000515400	2093	464	86098524	86098595	1054	1124	243	267
ENST00000515650	2411	464	86098524	86098595	1679	1749	243	267
ENST00000638313	3988	464	86098524	86098595	1110	1180	243	267
ENST00000641051	5755	464	86098524	86098595	1720	1790	243	267
ENST00000641066	6572	464	86098524	86098595	1154	1224	243	267
ENST00000641157	2466	464	86098524	86098595	1091	1161	243	267
ENST00000641207	2763	464	86098524	86098595	1342	1412	243	267
ENST00000641341	4001	464	86098524	86098595	1123	1193	243	267
ENST00000641462	6713	464	86098524	86098595	1292	1362	243	267
ENST00000641647	3379	464	86098524	86098595	1439	1509	243	267
ENST00000641823	2749	464	86098524	86098595	1327	1397	243	267
ENST00000641902	3842	464	86098524	86098595	1086	1156	243	267
ENST00000641952	5226	464	86098524	86098595	1197	1267	243	267
ENST00000641983	6789	464	86098524	86098595	1358	1428	243	267

Lost protein functional features of individual exon skipping events in ROSMAP.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1

Lost protein functional features of individual exon skipping events in MSBB.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1

Lost protein functional features of individual exon skipping events in Mayo.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	1	464	Chain	ID=PRO_0000186277;Note=Mitogen-activated protein kinase 10
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	64	359	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1
P53779	243	267	244	258	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3OY1

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3'-UTR located exon skipping events that lost miRNA binding sites in MAPK10

3'-UTR exon skipping evnets lost miRNA binding.

Tissue type	ENST	Exon skip start	Exon skip end	microRNA	Binding site by TargetScan	Binding type by TargetScan	Bdinding site by miRanda	Score of miRanda	Energy by miRanda
Mayo	ENST00000641647	86321844	86322029	hsa-miR-4421	chr4:86321882-86321889	8mer-1a	chr4:86321866-86321889	154.00	-19.63
Mayo	ENST00000641647	86321844	86322029	hsa-miR-5699-3p	chr4:86321882-86321889	8mer-1a	chr4:86321866-86321889	154.00	-19.63
Mayo	ENST00000641051	86453030	86453181	hsa-miR-7162-5p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
Mayo	ENST00000641647	86321844	86322029	hsa-miR-4482-3p	chr4:86322013-86322020	8mer-1a	chr4:86321999-86322020	155.00	-13.54
Mayo	ENST00000641207	86340339	86340423	hsa-miR-6756-3p	chr4:86340405-86340412	8mer-1a	chr4:86340392-86340412	156.00	-25.84
Mayo	ENST00000641647	86321844	86322029	hsa-miR-2392	chr4:86321991-86321998	8mer-1a	chr4:86321980-86321998	160.00	-25.48
Mayo	ENST00000641952	86354530	86354644	hsa-miR-337-3p	chr4:86354553-86354560	8mer-1a	chr4:86354540-86354560	151.00	-13.10
Mayo	ENST00000641647	86321844	86322029	hsa-miR-1273h-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641207	86340339	86340423	hsa-miR-4727-5p	chr4:86340394-86340401	8mer-1a	chr4:86340386-86340409	159.00	-26.01
Mayo	ENST00000641647	86321844	86322029	hsa-miR-6779-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641823	86335076	86335156	hsa-miR-6866-5p	chr4:86335134-86335141	8mer-1a	chr4:86335132-86335151	157.00	-26.24
Mayo	ENST00000641647	86321844	86322029	hsa-miR-6780a-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641051	86453030	86453181	hsa-miR-4316	chr4:86453136-86453143	8mer-1a	chr4:86453122-86453145	158.00	-20.32
Mayo	ENST00000641051	86453030	86453181	hsa-miR-4530	chr4:86453161-86453168	8mer-1a	chr4:86453153-86453175	160.00	-32.15
Mayo	ENST00000641051	86453030	86453181	hsa-miR-520f-5p	chr4:86453045-86453052	8mer-1a	chr4:86453031-86453052	151.00	-16.22
Mayo	ENST00000641051	86453030	86453181	hsa-miR-516b-3p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
Mayo	ENST00000641051	86453030	86453181	hsa-miR-516a-3p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
Mayo	ENST00000641207	86340339	86340423	hsa-miR-3127-3p	chr4:86340405-86340412	8mer-1a	chr4:86340392-86340412	156.00	-25.84
Mayo	ENST00000641647	86321844	86322029	hsa-miR-4784	chr4:86321942-86321949	8mer-1a	chr4:86321932-86321954	166.00	-22.54
Mayo	ENST00000641647	86321844	86322029	hsa-miR-4786-5p	chr4:86321910-86321917	8mer-1a	chr4:86321897-86321917	158.00	-27.92
Mayo	ENST00000641207	86340339	86340423	hsa-miR-6817-5p	chr4:86340393-86340400	8mer-1a	chr4:86340386-86340409	159.00	-26.01
Mayo	ENST00000641051	86453030	86453181	hsa-miR-4763-3p	chr4:86453113-86453120	8mer-1a	chr4:86453099-86453120	153.00	-29.00
Mayo	ENST00000641207	86340339	86340423	hsa-miR-544b	chr4:86340374-86340381	8mer-1a	chr4:86340362-86340382	162.00	-23.60
Mayo	ENST00000641647	86321844	86322029	hsa-miR-4455	chr4:86321986-86321993	8mer-1a	chr4:86321980-86321998	160.00	-25.48
Mayo	ENST00000641647	86321844	86322029	hsa-miR-887-5p	chr4:86321952-86321959	8mer-1a	chr4:86321939-86321959	146.00	-14.98
Mayo	ENST00000641823	86335076	86335156	hsa-miR-3650	chr4:86335119-86335126	8mer-1a	chr4:86335117-86335139	164.00	-26.02
Mayo	ENST00000641207	86340339	86340423	hsa-miR-1200	chr4:86340375-86340382	8mer-1a	chr4:86340362-86340382	162.00	-23.60
Mayo	ENST00000641952	86354530	86354644	hsa-miR-6837-3p	chr4:86354599-86354606	8mer-1a	chr4:86354584-86354610	173.00	-23.55
Mayo	ENST00000641647	86321844	86322029	hsa-miR-593-3p	chr4:86321879-86321886	8mer-1a	chr4:86321866-86321889	154.00	-19.63
Mayo	ENST00000641952	86354530	86354644	hsa-miR-183-3p	chr4:86354568-86354575	8mer-1a	chr4:86354559-86354582	159.00	-12.67
Mayo	ENST00000641647	86321844	86322029	hsa-miR-3150b-3p	chr4:86321942-86321949	8mer-1a	chr4:86321932-86321954	166.00	-22.54
Mayo	ENST00000641051	86453030	86453181	hsa-miR-1207-5p	chr4:86453113-86453120	8mer-1a	chr4:86453099-86453120	153.00	-29.00
Mayo	ENST00000641647	86321844	86322029	hsa-miR-30b-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641823	86335076	86335156	hsa-miR-3911	chr4:86335116-86335123	8mer-1a	chr4:86335108-86335132	159.00	-25.88
Mayo	ENST00000641647	86321844	86322029	hsa-miR-3689c	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641647	86321844	86322029	hsa-miR-3689a-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641647	86321844	86322029	hsa-miR-3689b-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
Mayo	ENST00000641207	86340339	86340423	hsa-miR-4769-3p	chr4:86340393-86340400	8mer-1a	chr4:86340386-86340409	159.00	-26.01
Mayo	ENST00000641823	86335076	86335156	hsa-miR-503-3p	chr4:86335106-86335113	8mer-1a	chr4:86335105-86335124	158.00	-18.90
Mayo	ENST00000641952	86354530	86354644	hsa-miR-4330	chr4:86354606-86354613	8mer-1a	chr4:86354603-86354625	153.00	-24.12
MSBB	ENST00000641647	86321844	86322029	hsa-miR-4421	chr4:86321882-86321889	8mer-1a	chr4:86321866-86321889	154.00	-19.63
MSBB	ENST00000641647	86321844	86322029	hsa-miR-5699-3p	chr4:86321882-86321889	8mer-1a	chr4:86321866-86321889	154.00	-19.63
MSBB	ENST00000641051	86453030	86453181	hsa-miR-7162-5p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
MSBB	ENST00000641647	86321844	86322029	hsa-miR-4482-3p	chr4:86322013-86322020	8mer-1a	chr4:86321999-86322020	155.00	-13.54
MSBB	ENST00000641207	86340339	86340423	hsa-miR-6756-3p	chr4:86340405-86340412	8mer-1a	chr4:86340392-86340412	156.00	-25.84
MSBB	ENST00000641647	86321844	86322029	hsa-miR-2392	chr4:86321991-86321998	8mer-1a	chr4:86321980-86321998	160.00	-25.48
MSBB	ENST00000641952	86354530	86354644	hsa-miR-337-3p	chr4:86354553-86354560	8mer-1a	chr4:86354540-86354560	151.00	-13.10
MSBB	ENST00000641647	86321844	86322029	hsa-miR-1273h-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641207	86340339	86340423	hsa-miR-4727-5p	chr4:86340394-86340401	8mer-1a	chr4:86340386-86340409	159.00	-26.01
MSBB	ENST00000641647	86321844	86322029	hsa-miR-6779-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641823	86335076	86335156	hsa-miR-6866-5p	chr4:86335134-86335141	8mer-1a	chr4:86335132-86335151	157.00	-26.24
MSBB	ENST00000641647	86321844	86322029	hsa-miR-6780a-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641051	86453030	86453181	hsa-miR-4316	chr4:86453136-86453143	8mer-1a	chr4:86453122-86453145	158.00	-20.32
MSBB	ENST00000641051	86453030	86453181	hsa-miR-4530	chr4:86453161-86453168	8mer-1a	chr4:86453153-86453175	160.00	-32.15
MSBB	ENST00000641051	86453030	86453181	hsa-miR-520f-5p	chr4:86453045-86453052	8mer-1a	chr4:86453031-86453052	151.00	-16.22
MSBB	ENST00000641051	86453030	86453181	hsa-miR-516b-3p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
MSBB	ENST00000641051	86453030	86453181	hsa-miR-516a-3p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
MSBB	ENST00000641207	86340339	86340423	hsa-miR-3127-3p	chr4:86340405-86340412	8mer-1a	chr4:86340392-86340412	156.00	-25.84
MSBB	ENST00000641647	86321844	86322029	hsa-miR-4784	chr4:86321942-86321949	8mer-1a	chr4:86321932-86321954	166.00	-22.54
MSBB	ENST00000641647	86321844	86322029	hsa-miR-4786-5p	chr4:86321910-86321917	8mer-1a	chr4:86321897-86321917	158.00	-27.92
MSBB	ENST00000641207	86340339	86340423	hsa-miR-6817-5p	chr4:86340393-86340400	8mer-1a	chr4:86340386-86340409	159.00	-26.01
MSBB	ENST00000641051	86453030	86453181	hsa-miR-4763-3p	chr4:86453113-86453120	8mer-1a	chr4:86453099-86453120	153.00	-29.00
MSBB	ENST00000641207	86340339	86340423	hsa-miR-544b	chr4:86340374-86340381	8mer-1a	chr4:86340362-86340382	162.00	-23.60
MSBB	ENST00000641647	86321844	86322029	hsa-miR-4455	chr4:86321986-86321993	8mer-1a	chr4:86321980-86321998	160.00	-25.48
MSBB	ENST00000641647	86321844	86322029	hsa-miR-887-5p	chr4:86321952-86321959	8mer-1a	chr4:86321939-86321959	146.00	-14.98
MSBB	ENST00000641823	86335076	86335156	hsa-miR-3650	chr4:86335119-86335126	8mer-1a	chr4:86335117-86335139	164.00	-26.02
MSBB	ENST00000641207	86340339	86340423	hsa-miR-1200	chr4:86340375-86340382	8mer-1a	chr4:86340362-86340382	162.00	-23.60
MSBB	ENST00000641952	86354530	86354644	hsa-miR-6837-3p	chr4:86354599-86354606	8mer-1a	chr4:86354584-86354610	173.00	-23.55
MSBB	ENST00000641647	86321844	86322029	hsa-miR-593-3p	chr4:86321879-86321886	8mer-1a	chr4:86321866-86321889	154.00	-19.63
MSBB	ENST00000641952	86354530	86354644	hsa-miR-183-3p	chr4:86354568-86354575	8mer-1a	chr4:86354559-86354582	159.00	-12.67
MSBB	ENST00000641647	86321844	86322029	hsa-miR-3150b-3p	chr4:86321942-86321949	8mer-1a	chr4:86321932-86321954	166.00	-22.54
MSBB	ENST00000641051	86453030	86453181	hsa-miR-1207-5p	chr4:86453113-86453120	8mer-1a	chr4:86453099-86453120	153.00	-29.00
MSBB	ENST00000641647	86321844	86322029	hsa-miR-30b-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641823	86335076	86335156	hsa-miR-3911	chr4:86335116-86335123	8mer-1a	chr4:86335108-86335132	159.00	-25.88
MSBB	ENST00000641647	86321844	86322029	hsa-miR-3689c	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641647	86321844	86322029	hsa-miR-3689a-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641647	86321844	86322029	hsa-miR-3689b-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
MSBB	ENST00000641207	86340339	86340423	hsa-miR-4769-3p	chr4:86340393-86340400	8mer-1a	chr4:86340386-86340409	159.00	-26.01
MSBB	ENST00000641823	86335076	86335156	hsa-miR-503-3p	chr4:86335106-86335113	8mer-1a	chr4:86335105-86335124	158.00	-18.90
MSBB	ENST00000641952	86354530	86354644	hsa-miR-4330	chr4:86354606-86354613	8mer-1a	chr4:86354603-86354625	153.00	-24.12
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-4421	chr4:86321882-86321889	8mer-1a	chr4:86321866-86321889	154.00	-19.63
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-5699-3p	chr4:86321882-86321889	8mer-1a	chr4:86321866-86321889	154.00	-19.63
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-7162-5p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-4482-3p	chr4:86322013-86322020	8mer-1a	chr4:86321999-86322020	155.00	-13.54
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-6756-3p	chr4:86340405-86340412	8mer-1a	chr4:86340392-86340412	156.00	-25.84
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-2392	chr4:86321991-86321998	8mer-1a	chr4:86321980-86321998	160.00	-25.48
ROSMAP	ENST00000641952	86354530	86354644	hsa-miR-337-3p	chr4:86354553-86354560	8mer-1a	chr4:86354540-86354560	151.00	-13.10
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-1273h-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-4727-5p	chr4:86340394-86340401	8mer-1a	chr4:86340386-86340409	159.00	-26.01
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-6779-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641823	86335076	86335156	hsa-miR-6866-5p	chr4:86335134-86335141	8mer-1a	chr4:86335132-86335151	157.00	-26.24
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-6780a-5p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-4316	chr4:86453136-86453143	8mer-1a	chr4:86453122-86453145	158.00	-20.32
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-4530	chr4:86453161-86453168	8mer-1a	chr4:86453153-86453175	160.00	-32.15
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-520f-5p	chr4:86453045-86453052	8mer-1a	chr4:86453031-86453052	151.00	-16.22
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-516b-3p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-516a-3p	chr4:86453075-86453082	8mer-1a	chr4:86453065-86453082	149.00	-21.51
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-3127-3p	chr4:86340405-86340412	8mer-1a	chr4:86340392-86340412	156.00	-25.84
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-4784	chr4:86321942-86321949	8mer-1a	chr4:86321932-86321954	166.00	-22.54
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-4786-5p	chr4:86321910-86321917	8mer-1a	chr4:86321897-86321917	158.00	-27.92
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-6817-5p	chr4:86340393-86340400	8mer-1a	chr4:86340386-86340409	159.00	-26.01
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-4763-3p	chr4:86453113-86453120	8mer-1a	chr4:86453099-86453120	153.00	-29.00
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-544b	chr4:86340374-86340381	8mer-1a	chr4:86340362-86340382	162.00	-23.60
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-4455	chr4:86321986-86321993	8mer-1a	chr4:86321980-86321998	160.00	-25.48
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-887-5p	chr4:86321952-86321959	8mer-1a	chr4:86321939-86321959	146.00	-14.98
ROSMAP	ENST00000641823	86335076	86335156	hsa-miR-3650	chr4:86335119-86335126	8mer-1a	chr4:86335117-86335139	164.00	-26.02
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-1200	chr4:86340375-86340382	8mer-1a	chr4:86340362-86340382	162.00	-23.60
ROSMAP	ENST00000641952	86354530	86354644	hsa-miR-6837-3p	chr4:86354599-86354606	8mer-1a	chr4:86354584-86354610	173.00	-23.55
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-593-3p	chr4:86321879-86321886	8mer-1a	chr4:86321866-86321889	154.00	-19.63
ROSMAP	ENST00000641952	86354530	86354644	hsa-miR-183-3p	chr4:86354568-86354575	8mer-1a	chr4:86354559-86354582	159.00	-12.67
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-3150b-3p	chr4:86321942-86321949	8mer-1a	chr4:86321932-86321954	166.00	-22.54
ROSMAP	ENST00000641051	86453030	86453181	hsa-miR-1207-5p	chr4:86453113-86453120	8mer-1a	chr4:86453099-86453120	153.00	-29.00
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-30b-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641823	86335076	86335156	hsa-miR-3911	chr4:86335116-86335123	8mer-1a	chr4:86335108-86335132	159.00	-25.88
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-3689c	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-3689a-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641647	86321844	86322029	hsa-miR-3689b-3p	chr4:86321951-86321958	8mer-1a	chr4:86321934-86321958	151.00	-21.80
ROSMAP	ENST00000641207	86340339	86340423	hsa-miR-4769-3p	chr4:86340393-86340400	8mer-1a	chr4:86340386-86340409	159.00	-26.01
ROSMAP	ENST00000641823	86335076	86335156	hsa-miR-503-3p	chr4:86335106-86335113	8mer-1a	chr4:86335105-86335124	158.00	-18.90
ROSMAP	ENST00000641952	86354530	86354644	hsa-miR-4330	chr4:86354606-86354613	8mer-1a	chr4:86354603-86354625	153.00	-24.12

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SNVs in the skipped exons for MAPK10

- Differential PSIs between mutated versus non-mutated samples.

- Depth of Coverage in the skipped exon of the mutated samples.

- Sashimi plot in the skipped exon of the mutated samples.

- Non-synonymous mutations located in the skipped exons.

Cancer type

Sample

ESID

Skipped exon start

Skipped exon end

Mutation start

Mutation end

Mutation type

Reference seq

Mutation seq

AAchange

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample

Skipped exon start

Skipped exon end

Mutation start

Mutation end

Mutation type

Reference seq

Mutation seq

AAchange

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AD stage-associated exon skippint events for MAPK10

Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR).

AD stage info

Cohort

Tissue

SE id

Coefficient

P-value

Chromosome

Strand

E1 start

E1 end

Skipped start

Skipped end

E2 start

E2 end

CDR

MSBB

IFG

exon_skip_247053

-4.297905e-01

2.245172e-02

chr4

86194336

86194407

86277050

86277223

86354530

86354644

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MAPK10

sQTL information located at the skipped exons.

Tissue type

Exon skip ID

SNP id

Location

P-value

FDR

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Correlation with RNA binding proteins (RBPs) for MAPK10

Correlated RBP and related information.

Tissue type

RBP name

Exon skip ID

Correlation coeifficient

P-value

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RelatedDrugs for MAPK10

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
P53779	approved\|investigational	DB12010	Fostamatinib	small molecule	P53779

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RelatedDiseases for MAPK10

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in RPSMAP, MSBB, and Mayo
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	3'-UTR located exon skipping events lost miRNA binding sites
	SNVs in the skipped exons with depth of coverage
	AD stage-associated exon skipping events
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Correlation with RNA binding proteins (RBPs)
	Related drugs with this gene
	Related diseases with this gene

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Gene summary for MAPK10

Gene structures and expression levels for MAPK10

Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for MAPK10

Open reading frame (ORF) annotation in the exon skipping event for MAPK10

Infer the effects of exon skipping event on protein functional features for MAPK10

3'-UTR located exon skipping events that lost miRNA binding sites in MAPK10

SNVs in the skipped exons for MAPK10

AD stage-associated exon skippint events for MAPK10

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MAPK10

Correlation with RNA binding proteins (RBPs) for MAPK10

RelatedDrugs for MAPK10

RelatedDiseases for MAPK10