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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in RPSMAP, MSBB, and Mayo

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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3'-UTR located exon skipping events lost miRNA binding sites

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SNVs in the skipped exons with depth of coverage

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AD stage-associated exon skipping events

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Correlation with RNA binding proteins (RBPs)

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Related drugs with this gene

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Related diseases with this gene

Gene summary for PCM1

check button Gene summary
Gene informationGene symbol

PCM1

Gene ID

5108

Gene namepericentriolar material 1
SynonymsPTC4|RET/PCM-1
Cytomap

8p22

Type of geneprotein-coding
Descriptionpericentriolar material 1 proteinPCM-1hPCM-1pericentriolar material 1, PCM1
Modification date20200327
UniProtAcc

A0A4W8VX11,

A0A5H1ZRS1,

A2RUU9,

B9EIS5,

D3DSQ0,

E5RGQ4,

E7EV93,

E9PGW9,

H0YBA1,

Q15154,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Gene structures and expression levels for PCM1

check buttonSkipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

ENSG00000078674
check button Differentially expressed gene analysis across multiple brain tissues between AD and control.
Tissue typeDEG directionBase mean exp.log2FC(AD/control)P-valueAdj. p-value

check button Differentially expressed isoform analysis across multiple brain tissues between AD and control.
gencode gene structure
Tissue typeDEG directionENSTTranscript info.Base mean exp.log2FC(AD/control)P-valueAdjc. p-value
CBUPENST00000518537.5PCM1-206:protein_coding:PCM17.274300e+018.694476e-011.050169e-094.549617e-08
CBUPENST00000518762.1PCM1-207:lncRNA:PCM19.502447e+001.873275e+008.535431e-081.854635e-06
CBUPENST00000518930.1PCM1-209:lncRNA:PCM11.225107e+001.595654e+001.106409e-048.061299e-04
CBUPENST00000325083.12PCM1-201:protein_coding:PCM12.115214e+021.341868e+001.263867e-049.032918e-04
CBUPENST00000523055.5PCM1-218:protein_coding:PCM18.016451e+008.545209e-015.795324e-043.264516e-03
CBUPENST00000517836.5PCM1-205:retained_intron:PCM11.335903e+019.555814e-018.337498e-032.993688e-02
TCUPENST00000523055.5PCM1-218:protein_coding:PCM16.840447e+009.247261e-011.650182e-042.399729e-03

check button Landscape of isoform expressions across multiple brain tissues between AD and control.
gencode gene structure

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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for PCM1

check button Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap).
boxplot

check button All exon skipping events in AD cohorts.
Exon skip IDchrExons involved in exon skippingSkipped exon
exon_skip_104846chr817962073:17962174:17963101:17963291:17964568:1796477017963101:17963291
exon_skip_106232chr817972673:17972687:17980591:17980755:17983233:1798328117980591:17980755
exon_skip_121226chr817923028:17923188:17924713:17924780:17935589:1793570617924713:17924780
exon_skip_122688chr818013882:18014036:18014584:18014840:18025361:1802545318014584:18014840
exon_skip_124337chr818013988:18014036:18014584:18014840:18025361:1802545318014584:18014840
exon_skip_131723chr817924744:17924780:17934706:17934858:17935589:1793570617934706:17934858
exon_skip_139306chr817938740:17939009:17939691:17939861:17947186:1794736317939691:17939861
exon_skip_150531chr817934706:17934858:17935589:17935706:17937134:1793732117935589:17935706
exon_skip_162394chr817980591:17980755:17983233:17983289:17985447:1798561917983233:17983289
exon_skip_174944chr817923028:17923188:17935589:17935706:17937134:1793732117935589:17935706
exon_skip_183324chr817993483:17993619:18006263:18006397:18009547:1800966518006263:18006397
exon_skip_186534chr817966980:17967170:17969577:17969748:17972329:1797264217969577:17969748
exon_skip_187043chr817960315:17960444:17962034:17962174:17963101:1796329117962034:17962174
exon_skip_189935chr817972673:17972687:17980591:17980755:17985447:1798551517980591:17980755
exon_skip_202517chr817952970:17953186:17955470:17955653:17956604:1795677717955470:17955653
exon_skip_219059chr817960315:17960444:17962034:17962174:17964568:1796476817962034:17962174
exon_skip_220869chr817980591:17980755:17983233:17983289:17985447:1798545617983233:17983289
exon_skip_221094chr817980591:17980755:17983233:17983289:17985447:1798551517983233:17983289
exon_skip_230781chr817939809:17939861:17940042:17940158:17947186:1794736317940042:17940158
exon_skip_235282chr817980221:17980755:17982540:17982637:17983233:1798328117982540:17982637
exon_skip_242636chr817947186:17947363:17950615:17950724:17952970:1795303517950615:17950724
exon_skip_25782chr817993553:17993619:18006263:18006397:18009547:1800966518006263:18006397
exon_skip_266732chr817962034:17962174:17963101:17963291:17964568:1796476817963101:17963291
exon_skip_270302chr817960317:17960444:17962034:17962174:17963101:1796329117962034:17962174
exon_skip_276761chr817972673:17972687:17980591:17980755:17985447:1798561917980591:17980755
exon_skip_284030chr817923028:17923188:17924713:17924780:17934706:1793485817924713:17924780
exon_skip_286214chr818014584:18014840:18025361:18025453:18025544:1802561118025361:18025453
exon_skip_45360chr817956604:17956777:17957264:17957421:17957540:1795777517957264:17957421
exon_skip_45602chr817939691:17939861:17940042:17940158:17947186:1794736317940042:17940158
exon_skip_4610chr818009547:18009744:18010609:18010668:18011237:1801125718010609:18010668
exon_skip_61127chr817972673:17972687:17980591:17980755:17985447:1798545617980591:17980755
exon_skip_66329chr817965999:17966218:17966328:17966473:17966980:1796717017966328:17966473
exon_skip_70678chr817962034:17962174:17963101:17963291:17964568:1796460717963101:17963291

check button Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control.
Exon skipping informationTissue typeAvg(PSIs) in ADAvg(PSIs) in controlDifference (PSI)Adj. p-value


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Open reading frame (ORF) annotation in the exon skipping event for PCM1

check button Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003250831795061517950724Frame-shift
ENST000003250831796310117963291Frame-shift
ENST000003250831796632817966473Frame-shift
ENST000003250831801458418014840Frame-shift
ENST000003250831796203417962174In-frame
ENST000003250831798059117980755In-frame
ENST000003250831800626318006397In-frame

check button Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003250831795061517950724Frame-shift
ENST000003250831796310117963291Frame-shift
ENST000003250831796632817966473Frame-shift
ENST000003250831801458418014840Frame-shift
ENST000003250831796203417962174In-frame
ENST000003250831798059117980755In-frame
ENST000003250831800626318006397In-frame

check button Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000003250831795061517950724Frame-shift
ENST000003250831795547017955653Frame-shift
ENST000003250831795726417957421Frame-shift
ENST000003250831796310117963291Frame-shift
ENST000003250831796632817966473Frame-shift
ENST000003250831796957717969748Frame-shift
ENST000003250831801458418014840Frame-shift
ENST000003250831793969117939861In-frame
ENST000003250831796203417962174In-frame
ENST000003250831798059117980755In-frame
ENST000003250831800626318006397In-frame
ENST000003250831801060918010668In-frame
ENST000003250831802536118025453In-frame

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Infer the effects of exon skipping event on protein functional features for PCM1

p-ENSG00000078674_img4.png
boxplot

check button Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000032508368372024179620341796217427632902774821
ENST000003250836837202417980591179807554384454713151369
ENST000003250836837202418006263180063975268540116091654

check button Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000032508368372024179620341796217427632902774821
ENST000003250836837202417980591179807554384454713151369
ENST000003250836837202418006263180063975268540116091654

check button Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000032508368372024179396911793986110531222204261
ENST0000032508368372024179620341796217427632902774821
ENST000003250836837202417980591179807554384454713151369
ENST000003250836837202418006263180063975268540116091654
ENST000003250836837202418010609180106685601565917201740
ENST000003250836837202418025361180254536282637319471978

check button Lost protein functional features of individual exon skipping events in ROSMAP.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q151547748214922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q1515477482122024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q15154131513694922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541315136913151370Alternative sequenceID=VSP_022611;Note=In isoform 2 and isoform 4. RYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSE->K;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
Q151541315136922024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541315136913181318Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R0L6
Q151541315136913201320Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R0L6
Q151541315136913261326Natural variantID=VAR_047382;Note=E->D;Dbxref=dbSNP:rs34932823
Q151541315136912791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q151541315136913421342Sequence conflictNote=V->L;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q151541315136913141315SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein
Q151541315136913691370SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein
Q15154160916544922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541609165422024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541609165412791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q151541609165416091610SiteNote=Breakpoint for translocation to form PCM1-RET fusion protein

check button Lost protein functional features of individual exon skipping events in MSBB.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q151547748214922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q1515477482122024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q15154131513694922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541315136913151370Alternative sequenceID=VSP_022611;Note=In isoform 2 and isoform 4. RYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSE->K;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
Q151541315136922024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541315136913181318Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R0L6
Q151541315136913201320Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R0L6
Q151541315136913261326Natural variantID=VAR_047382;Note=E->D;Dbxref=dbSNP:rs34932823
Q151541315136912791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q151541315136913421342Sequence conflictNote=V->L;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q151541315136913141315SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein
Q151541315136913691370SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein
Q15154160916544922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541609165422024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541609165412791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q151541609165416091610SiteNote=Breakpoint for translocation to form PCM1-RET fusion protein

check button Lost protein functional features of individual exon skipping events in Mayo.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q1515420426122024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q15154204261218301Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q151547748214922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q1515477482122024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q15154131513694922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541315136913151370Alternative sequenceID=VSP_022611;Note=In isoform 2 and isoform 4. RYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSE->K;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
Q151541315136922024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541315136913181318Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R0L6
Q151541315136913201320Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9R0L6
Q151541315136913261326Natural variantID=VAR_047382;Note=E->D;Dbxref=dbSNP:rs34932823
Q151541315136912791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q151541315136913421342Sequence conflictNote=V->L;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q151541315136913141315SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein
Q151541315136913691370SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein
Q15154160916544922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541609165422024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541609165412791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q151541609165416091610SiteNote=Breakpoint for translocation to form PCM1-RET fusion protein
Q15154172017404922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541720174022024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541720174017301730Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163;Dbxref=PMID:1
Q151541720174012791799RegionNote=Interaction with HAP1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9361024;Dbxref=PMID:9361024
Q15154194719784922024Alternative sequenceID=VSP_022610;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q151541947197818381947Alternative sequenceID=VSP_059401;Note=In isoform 4. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q151541947197822024ChainID=PRO_0000274037;Note=Pericentriolar material 1 protein
Q151541947197819581958Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:21406692;Dbxref=PMID:21406692
Q151541947197819771977Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:23186163;Dbxref=PMID:19690332,PMID:23186163
Q151541947197819132024RegionNote=Interaction with BBS4;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15107855;Dbxref=PMID:15107855
Q151541947197819471948SiteNote=Breakpoint for translocation to form PCM1-JAK2 fusion protein


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3'-UTR located exon skipping events that lost miRNA binding sites in PCM1

check button 3'-UTR exon skipping evnets lost miRNA binding.
Tissue typeENSTExon skip startExon skip endmicroRNABinding site by TargetScanBinding type by TargetScanBdinding site by miRandaScore of miRandaEnergy by miRanda

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SNVs in the skipped exons for PCM1

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Depth of Coverage in the skipped exon of the mutated samples.

check button - Sashimi plot in the skipped exon of the mutated samples.

check button - Non-synonymous mutations located in the skipped exons.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

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AD stage-associated exon skippint events for PCM1

check button Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR).
AD stage infoCohortTissueSE idCoefficient P-valueChromosomeStrandE1 startE1 endSkipped startSkipped endE2 startE2 end
ADstageMSBBIFGexon_skip_266732-4.699848e-011.161603e-02chr8+179620341796217417963101179632911796456817964768

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PCM1

check button sQTL information located at the skipped exons.
Tissue typeExon skip IDSNP idLocationP-valueFDR
TCexon_skip_121226rs850845chr8:178513951.757940e-089.402105e-06
TCexon_skip_121226rs2653426chr8:178969521.757940e-089.402105e-06
TCexon_skip_121226rs432070chr8:179014801.757940e-089.402105e-06
TCexon_skip_121226rs426372chr8:179058561.757940e-089.402105e-06
TCexon_skip_121226rs439968chr8:179116841.757940e-089.402105e-06
TCexon_skip_121226rs439511chr8:179879381.757940e-089.402105e-06
TCexon_skip_121226rs2237848chr8:180170956.448902e-061.708522e-03
TCexon_skip_45602rs12056521chr8:179657907.385740e-051.282829e-02
TCexon_skip_45602rs12056629chr8:180033547.385740e-051.282829e-02
HCCexon_skip_121226rs439511chr8:179879382.646559e-131.428293e-10
HCCexon_skip_121226rs423944chr8:178911841.141898e-103.942452e-08
HCCexon_skip_121226rs2653426chr8:178969521.141898e-103.942452e-08
HCCexon_skip_121226rs393221chr8:178981591.141898e-103.942452e-08
HCCexon_skip_121226rs377085chr8:178998931.141898e-103.942452e-08
HCCexon_skip_121226rs426354chr8:179000871.141898e-103.942452e-08
HCCexon_skip_121226rs426680chr8:179002441.141898e-103.942452e-08
HCCexon_skip_121226rs418656chr8:179002981.141898e-103.942452e-08
HCCexon_skip_121226rs432070chr8:179014801.141898e-103.942452e-08
HCCexon_skip_121226rs365338chr8:179047631.141898e-103.942452e-08
HCCexon_skip_121226rs402227chr8:179051371.141898e-103.942452e-08
HCCexon_skip_121226rs426372chr8:179058561.141898e-103.942452e-08
HCCexon_skip_121226rs392939chr8:179058931.141898e-103.942452e-08
HCCexon_skip_121226rs365509chr8:179068491.141898e-103.942452e-08
HCCexon_skip_121226rs850845chr8:178513951.086383e-093.216238e-07
HCCexon_skip_121226rs11987695chr8:179235762.406009e-096.691459e-07
HCCexon_skip_121226rs3850746chr8:179300272.406009e-096.691459e-07
HCCexon_skip_121226rs2237848chr8:180170954.162356e-091.101995e-06
HCCexon_skip_121226rs392989chr8:179060866.612733e-081.375208e-05
HCCexon_skip_121226rs2517297chr8:178761038.454268e-061.087760e-03
HCCexon_skip_121226rs9325823chr8:178783627.267096e-056.986012e-03
HCCexon_skip_121226rs3853531chr8:178914117.267096e-056.986012e-03
HCCexon_skip_121226rs2157650chr8:178478637.607451e-057.242055e-03
HCCexon_skip_121226rs6586661chr8:178556118.125303e-057.678029e-03
HCCexon_skip_121226rs6586662chr8:178556818.125303e-057.678029e-03
PCCexon_skip_121226rs439511chr8:179879381.331366e-053.251656e-03
PCCexon_skip_121226rs850845chr8:178513952.437076e-055.467248e-03
PCCexon_skip_121226rs423944chr8:178911847.074857e-051.314276e-02
PCCexon_skip_121226rs2653426chr8:178969527.074857e-051.314276e-02
PCCexon_skip_121226rs393221chr8:178981597.074857e-051.314276e-02
PCCexon_skip_121226rs377085chr8:178998937.074857e-051.314276e-02
PCCexon_skip_121226rs426354chr8:179000877.074857e-051.314276e-02
PCCexon_skip_121226rs426680chr8:179002447.074857e-051.314276e-02
PCCexon_skip_121226rs418656chr8:179002987.074857e-051.314276e-02
PCCexon_skip_121226rs432070chr8:179014807.074857e-051.314276e-02
PCCexon_skip_121226rs365338chr8:179047637.074857e-051.314276e-02
PCCexon_skip_121226rs402227chr8:179051377.074857e-051.314276e-02
PCCexon_skip_121226rs392939chr8:179058937.074857e-051.314276e-02
PCCexon_skip_121226rs392989chr8:179060867.074857e-051.314276e-02
PCCexon_skip_121226rs365509chr8:179068497.074857e-051.314276e-02
PCCexon_skip_121226rs426372chr8:179058567.074857e-051.314276e-02
PCCexon_skip_45602rs208021chr8:180218831.466658e-042.347753e-02
PCCexon_skip_121226rs2237848chr8:180170953.305523e-044.405938e-02
DLPFCexon_skip_121226rs850845chr8:178513953.031751e-063.897170e-04
DLPFCexon_skip_121226rs392989chr8:179060866.948472e-068.139506e-04
DLPFCexon_skip_121226rs423944chr8:178911841.068907e-051.194337e-03
DLPFCexon_skip_121226rs2653426chr8:178969521.068907e-051.194337e-03
DLPFCexon_skip_121226rs393221chr8:178981591.068907e-051.194337e-03
DLPFCexon_skip_121226rs377085chr8:178998931.068907e-051.194337e-03
DLPFCexon_skip_121226rs426354chr8:179000871.068907e-051.194337e-03
DLPFCexon_skip_121226rs426680chr8:179002441.068907e-051.194337e-03
DLPFCexon_skip_121226rs418656chr8:179002981.068907e-051.194337e-03
DLPFCexon_skip_121226rs432070chr8:179014801.068907e-051.194337e-03
DLPFCexon_skip_121226rs365338chr8:179047631.068907e-051.194337e-03
DLPFCexon_skip_121226rs402227chr8:179051371.068907e-051.194337e-03
DLPFCexon_skip_121226rs392939chr8:179058931.068907e-051.194337e-03
DLPFCexon_skip_121226rs365509chr8:179068491.068907e-051.194337e-03
DLPFCexon_skip_121226rs426372chr8:179058561.068907e-051.194337e-03
DLPFCexon_skip_121226rs11987695chr8:179235764.570281e-054.279335e-03
DLPFCexon_skip_121226rs3850746chr8:179300274.570281e-054.279335e-03
DLPFCexon_skip_121226rs2237848chr8:180170954.751029e-054.433666e-03
DLPFCexon_skip_121226rs439511chr8:179879385.472927e-055.009393e-03

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Correlation with RNA binding proteins (RBPs) for PCM1

check button Correlated RBP and related information.
Tissue typeRBP nameExon skip IDCorrelation coeifficientP-value
CBELAVL1exon_skip_2130665.266485e-012.702574e-12
CBMATR3exon_skip_2130664.684458e-011.018856e-09
CBSRSF4exon_skip_2130665.095183e-011.742369e-11
CBRBM41exon_skip_2130664.434498e-019.427055e-09
DLPFCSRSF11exon_skip_213066-4.718617e-011.189085e-17
FLRALYLexon_skip_2130664.450864e-015.035294e-11
HCCMSI1exon_skip_45602-4.176935e-011.068857e-12
IFGCNOT4exon_skip_1212264.457238e-011.744623e-02
IFGUNKexon_skip_1212265.014389e-016.559332e-03
IFGRBM4Bexon_skip_1212264.134578e-012.874357e-02
IFGENOX1exon_skip_2767615.186833e-014.685588e-03
IFGSFPQexon_skip_1623945.072020e-015.873006e-03
IFGSF1exon_skip_1623944.207939e-012.576080e-02
IFGPABPC5exon_skip_1623944.205967e-012.583753e-02

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RelatedDrugs for PCM1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PCM1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource