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![]() | Open reading frame (ORF) annotation in the exon skipping event |
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![]() | 3'-UTR located exon skipping events lost miRNA binding sites |
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![]() | Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for ANXA7 |
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Gene information | Gene symbol | ANXA7 | Gene ID | 310 |
Gene name | annexin A7 | |
Synonyms | ANX7|SNX|SYNEXIN | |
Cytomap | 10q22.2 | |
Type of gene | protein-coding | |
Description | annexin A7annexin VIIannexin-7 | |
Modification date | 20200313 | |
UniProtAcc | B9ZVT2, P20073, | |
Context |
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Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for ANXA7 |
![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
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Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
CB | DOWN | ENST00000463788.1 | ANXA7-204:lncRNA:ANXA7 | 1.563530e+01 | -3.594876e+00 | 1.048682e-14 | 3.658280e-12 |
TC | UP | ENST00000492380.1 | ANXA7-205:lncRNA:ANXA7 | 5.978261e+01 | 8.946129e-01 | 2.013323e-05 | 4.500970e-04 |
TC | DOWN | ENST00000463788.1 | ANXA7-204:lncRNA:ANXA7 | 9.459213e+00 | -1.730121e+00 | 5.708192e-05 | 1.036562e-03 |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for ANXA7 |
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Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
exon_skip_112183 | chr10 | 73398181:73398385:73400803:73400857:73414012:73414058 | 73400803:73400857 |
exon_skip_159424 | chr10 | 73397164:73397274:73398181:73398385:73400803:73400857 | 73398181:73398385 |
exon_skip_181585 | chr10 | 73398181:73398385:73400803:73400857:73408195:73408285 | 73400803:73400857 |
exon_skip_184137 | chr10 | 73376148:73376217:73377445:73377566:73378911:73378958 | 73377445:73377566 |
exon_skip_234558 | chr10 | 73388312:73388414:73396044:73396109:73396519:73396583 | 73396044:73396109 |
exon_skip_235650 | chr10 | 73397164:73397274:73398181:73398385:73414012:73414058 | 73398181:73398385 |
exon_skip_238377 | chr10 | 73375649:73376217:73377445:73377566:73378911:73378958 | 73377445:73377566 |
exon_skip_285808 | chr10 | 73383577:73383690:73387689:73387783:73388312:73388414 | 73387689:73387783 |
exon_skip_2984 | chr10 | 73375649:73376217:73378911:73379023:73379879:73379954 | 73378911:73379023 |
exon_skip_40542 | chr10 | 73383261:73383345:73383577:73383690:73387689:73387783 | 73383577:73383690 |
exon_skip_50987 | chr10 | 73398352:73398385:73400803:73400857:73414012:73414058 | 73400803:73400857 |
exon_skip_79290 | chr10 | 73398181:73398385:73400803:73400857:73408195:73408403 | 73400803:73400857 |
exon_skip_82005 | chr10 | 73376148:73376217:73378911:73379023:73379879:73379954 | 73378911:73379023 |
exon_skip_84411 | chr10 | 73388312:73388414:73396044:73396109:73396519:73396537 | 73396044:73396109 |
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Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
exon_skip_234558 | MSBB_STG | 5.043284e-01 | 6.775000e-01 | -1.731716e-01 | 4.707288e-03 |
exon_skip_234558 | MSBB_PG | 4.425000e-01 | 5.782759e-01 | -1.357759e-01 | 8.490907e-04 |
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Open reading frame (ORF) annotation in the exon skipping event for ANXA7 |
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ENST | Start of skipped exon | End of skipped exon | ORF |
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ENST | Start of skipped exon | End of skipped exon | ORF |
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ENST | Start of skipped exon | End of skipped exon | ORF |
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Infer the effects of exon skipping event on protein functional features for ANXA7 |
p-ENSG00000138279_img4.png![]() |
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ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
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ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
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ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
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UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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3'-UTR located exon skipping events that lost miRNA binding sites in ANXA7 |
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Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for ANXA7 |
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Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for ANXA7 |
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AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ANXA7 |
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Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for ANXA7 |
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Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
CB | ELAVL4 | exon_skip_234558 | 4.110451e-01 | 7.366709e-08 |
CB | TIA1 | exon_skip_234558 | 6.053744e-01 | 2.850735e-17 |
CB | HNRNPA0 | exon_skip_234558 | 4.979034e-01 | 2.429422e-11 |
CB | RALYL | exon_skip_234558 | 7.039118e-01 | 4.248095e-25 |
CB | PTBP3 | exon_skip_234558 | 4.321989e-01 | 1.279683e-08 |
CB | PCBP1 | exon_skip_50987 | -4.290744e-01 | 1.854357e-08 |
DLPFC | ELAVL4 | exon_skip_234558 | 5.580379e-01 | 3.187635e-29 |
DLPFC | RC3H1 | exon_skip_234558 | 5.770561e-01 | 1.417011e-31 |
DLPFC | ENOX1 | exon_skip_234558 | 4.359499e-01 | 3.324061e-17 |
DLPFC | RALYL | exon_skip_234558 | 4.281998e-01 | 1.360250e-16 |
DLPFC | PTBP3 | exon_skip_234558 | 4.359720e-01 | 3.310569e-17 |
FL | ELAVL4 | exon_skip_234558 | 6.520936e-01 | 2.337461e-25 |
FL | HNRNPA0 | exon_skip_234558 | 5.647580e-01 | 4.469609e-18 |
FL | RALYL | exon_skip_234558 | 5.901895e-01 | 5.693561e-20 |
FL | PTBP1 | exon_skip_234558 | -4.759604e-01 | 1.372445e-12 |
FL | HNRNPL | exon_skip_234558 | 4.918245e-01 | 1.864270e-13 |
FL | NOVA1 | exon_skip_234558 | 4.636015e-01 | 6.062591e-12 |
HCC | RBMS3 | exon_skip_234558 | -4.751881e-01 | 8.754170e-17 |
HCC | RBM6 | exon_skip_234558 | -6.901599e-01 | 5.994339e-40 |
HCC | TIA1 | exon_skip_234558 | -5.533835e-01 | 2.648008e-23 |
HCC | IGF2BP2 | exon_skip_234558 | -4.259736e-01 | 1.845612e-13 |
HCC | TRNAU1AP | exon_skip_234558 | -5.264113e-01 | 7.312309e-21 |
HCC | PCBP1 | exon_skip_234558 | -4.468461e-01 | 8.348253e-15 |
HCC | FUBP1 | exon_skip_234558 | -5.329071e-01 | 1.977072e-21 |
HCC | ENOX1 | exon_skip_234558 | -4.006905e-01 | 5.961980e-12 |
HCC | PTBP1 | exon_skip_234558 | -7.847148e-01 | 3.164804e-58 |
HCC | SRSF4 | exon_skip_234558 | -5.761511e-01 | 1.523989e-25 |
IFG | ELAVL4 | exon_skip_234558 | 5.472737e-01 | 2.578097e-03 |
IFG | TIA1 | exon_skip_234558 | -4.179231e-01 | 2.689652e-02 |
IFG | IGF2BP2 | exon_skip_234558 | -4.982826e-01 | 6.963141e-03 |
IFG | HNRNPA0 | exon_skip_234558 | 4.120713e-01 | 2.933751e-02 |
IFG | RALYL | exon_skip_234558 | 4.705403e-01 | 1.150451e-02 |
IFG | PTBP1 | exon_skip_234558 | -6.024398e-01 | 6.929241e-04 |
PCC | ELAVL4 | exon_skip_234558 | 6.708372e-01 | 1.798512e-29 |
PCC | RBM6 | exon_skip_234558 | -4.963967e-01 | 8.919612e-15 |
PCC | RALYL | exon_skip_234558 | 5.493114e-01 | 2.401579e-18 |
PCC | PTBP1 | exon_skip_234558 | -7.461374e-01 | 1.713747e-39 |
PG | ELAVL4 | exon_skip_234558 | 8.423422e-01 | 1.358616e-55 |
PG | ELAVL1 | exon_skip_234558 | 4.944310e-01 | 7.516150e-14 |
PG | TIA1 | exon_skip_234558 | 4.029494e-01 | 2.757280e-09 |
PG | TRNAU1AP | exon_skip_234558 | 4.265846e-01 | 2.445586e-10 |
PG | PCBP1 | exon_skip_234558 | 4.783001e-01 | 6.061027e-13 |
PG | RC3H1 | exon_skip_234558 | 4.306913e-01 | 1.574385e-10 |
PG | FUBP1 | exon_skip_234558 | 4.329691e-01 | 1.230021e-10 |
PG | ENOX1 | exon_skip_234558 | 4.953042e-01 | 6.691976e-14 |
PG | HNRNPA0 | exon_skip_234558 | 6.528788e-01 | 6.388749e-26 |
PG | RALYL | exon_skip_234558 | 7.839300e-01 | 2.834662e-43 |
PG | PTBP1 | exon_skip_234558 | -4.802002e-01 | 4.766681e-13 |
PG | HNRNPL | exon_skip_234558 | 6.322776e-01 | 6.000833e-24 |
PG | NOVA1 | exon_skip_234558 | 6.686310e-01 | 1.549848e-27 |
STG | ELAVL4 | exon_skip_234558 | 6.835752e-01 | 8.228898e-14 |
STG | IGF2BP2 | exon_skip_234558 | -4.009556e-01 | 8.196229e-05 |
STG | PCBP1 | exon_skip_234558 | 4.311634e-01 | 1.984376e-05 |
STG | HNRNPA0 | exon_skip_234558 | 6.021638e-01 | 2.720096e-10 |
STG | RALYL | exon_skip_234558 | 6.904513e-01 | 3.675848e-14 |
STG | PTBP1 | exon_skip_234558 | -4.731237e-01 | 2.180208e-06 |
STG | HNRNPL | exon_skip_234558 | 4.720006e-01 | 2.321957e-06 |
STG | NOVA1 | exon_skip_234558 | 6.225549e-01 | 4.451112e-11 |
TC | ELAVL4 | exon_skip_84411 | 8.362557e-01 | 4.449206e-43 |
TC | RBM6 | exon_skip_84411 | -4.042407e-01 | 1.150329e-07 |
TC | ENOX1 | exon_skip_84411 | 5.085541e-01 | 6.622371e-12 |
TC | HNRNPA0 | exon_skip_84411 | 7.564453e-01 | 6.143302e-31 |
TC | PUF60 | exon_skip_84411 | 4.271927e-01 | 1.764755e-08 |
TC | RALYL | exon_skip_84411 | 8.716141e-01 | 8.683539e-51 |
TC | PTBP1 | exon_skip_84411 | -4.747432e-01 | 2.262259e-10 |
TC | PTBP3 | exon_skip_84411 | 4.680337e-01 | 4.359579e-10 |
TC | HNRNPL | exon_skip_84411 | 5.074244e-01 | 7.499169e-12 |
TC | NOVA1 | exon_skip_84411 | 7.847463e-01 | 1.211063e-34 |
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RelatedDrugs for ANXA7 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ANXA7 |
![]() (DisGeNet 4.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |