|
||||||
|
 | |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| 3'-UTR located exon skipping events lost miRNA binding sites |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| |
| |
|
Gene summary for CDC26 |
 Gene summary |
| Gene information | Gene symbol | CDC26 | Gene ID | 246184 |
| Gene name | cell division cycle 26 | |
| Synonyms | ANAPC12|APC12|C9orf17 | |
| Cytomap | 9q32 | |
| Type of gene | protein-coding | |
| Description | anaphase-promoting complex subunit CDC26CDC26 subunit of anaphase promoting complexanaphase-promoting complex subunit 12cell division cycle 26 homologcell division cycle protein 26 homolog | |
| Modification date | 20200313 | |
| UniProtAcc | A0A024R832, Q8NHZ8, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| CDC26 | GO:0070979 | protein K11-linked ubiquitination | 18485873 |
Top |
Gene structures and expression levels for CDC26 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
ENSG00000176386
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
 |
Top |
Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for CDC26 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
 |
| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_102197 | chr9 | 113255835:113256043:113256455:113256548:113272427:113272548 | 113256455:113256548 |
| exon_skip_122965 | chr9 | 113255835:113256043:113256455:113256548:113272427:113272520 | 113256455:113256548 |
| exon_skip_138215 | chr9 | 113272427:113272548:113273329:113273438:113275382:113275549 | 113273329:113273438 |
| exon_skip_55568 | chr9 | 113266992:113267439:113272427:113272548:113273329:113273410 | 113272427:113272548 |
| exon_skip_85017 | chr9 | 113266992:113267439:113272427:113272548:113273329:113273438 | 113272427:113272548 |
| exon_skip_92569 | chr9 | 113256455:113256548:113272427:113272548:113273329:113273410 | 113272427:113272548 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |