|
||||||
|
 | |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| 3'-UTR located exon skipping events lost miRNA binding sites |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| |
| |
|
Gene summary for ADGRL2 |
 Gene summary |
| Gene information | Gene symbol | ADGRL2 | Gene ID | 23266 |
| Gene name | adhesion G protein-coupled receptor L2 | |
| Synonyms | CIRL2|CL2|LEC1|LPHH1|LPHN2 | |
| Cytomap | 1p31.1 | |
| Type of gene | protein-coding | |
| Description | adhesion G protein-coupled receptor L2calcium-independent alpha-latrotoxin receptor 2latrophilin homolog 1latrophilin-2lectomedin-1 | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
Gene structures and expression levels for ADGRL2 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
ENSG00000117114
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PG | DOWN | ENST00000473719.5 | ADGRL2-219:lncRNA:ADGRL2 | 1.158287e+01 | -8.102533e-01 | 5.247023e-06 | 3.129843e-04 |
| PG | DOWN | ENST00000449420.5 | ADGRL2-213:protein_coding:ADGRL2 | 7.629068e+01 | -1.061876e+00 | 3.465699e-03 | 3.531922e-02 |
| CB | DOWN | ENST00000469377.6 | ADGRL2-217:lncRNA:ADGRL2 | 5.059414e+00 | -1.466066e+00 | 1.571820e-03 | 7.545367e-03 |
| TC | UP | ENST00000319517.10 | ADGRL2-201:protein_coding:ADGRL2 | 1.382744e+02 | 1.417001e+00 | 1.982413e-03 | 1.666724e-02 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
 |
Top |
Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for ADGRL2 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
 |
| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_117633 | chr1 | 81980795:81980839:81981124:81981150:81981808:81981976 | 81981124:81981150 |
| exon_skip_132198 | chr1 | 81836885:81837057:81907017:81907230:81936728:81936837 | 81907017:81907230 |
| exon_skip_141357 | chr1 | 81761811:81761852:81836885:81837057:81907017:81907230 | 81836885:81837057 |
| exon_skip_164916 | chr1 | 81979922:81979960:81980795:81980839:81981808:81981976 | 81980795:81980839 |
| exon_skip_172441 | chr1 | 81984583:81984711:81985259:81985355:81990391:81990681 | 81985259:81985355 |
| exon_skip_185745 | chr1 | 81987289:81987341:81989657:81989709:81990391:81990681 | 81989657:81989709 |
| exon_skip_192626 | chr1 | 81445021:81445089:81579300:81579380:81580876:81580980 | 81579300:81579380 |
| exon_skip_194320 | chr1 | 81951965:81952142:81952987:81953025:81955877:81956060 | 81952987:81953025 |
| exon_skip_210075 | chr1 | 81951962:81952142:81952987:81953025:81955877:81956060 | 81952987:81953025 |
| exon_skip_230464 | chr1 | 81985259:81985355:81987260:81987341:81990391:81990681 | 81987260:81987341 |
| exon_skip_282885 | chr1 | 81986901:81987029:81987869:81987886:81990391:81990681 | 81987869:81987886 |
| exon_skip_283928 | chr1 | 81951957:81952142:81952987:81953025:81955877:81956060 | 81952987:81953025 |
| exon_skip_44717 | chr1 | 81984583:81984711:81985259:81985355:81990391:81992196 | 81985259:81985355 |
| exon_skip_73328 | chr1 | 81936728:81936837:81942034:81942045:81942969:81943769 | 81942034:81942045 |
| exon_skip_73456 | chr1 | 81985259:81985355:81986901:81987029:81990391:81990681 | 81986901:81987029 |
| exon_skip_73494 | chr1 | 81985259:81985355:81987289:81987341:81990391:81990681 | 81987289:81987341 |
| exon_skip_75525 | chr1 | 81955877:81956060:81966058:81966183:81966404:81966435 | 81966058:81966183 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
 |
| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_194320 | Mayo_TC | 5.458537e-01 | 6.896364e-01 | -1.437827e-01 | 2.329503e-07 |
Top |
Open reading frame (ORF) annotation in the exon skipping event for ADGRL2 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000370717 | 81952987 | 81953025 | In-frame |
| ENST00000370728 | 81952987 | 81953025 | In-frame |
| ENST00000370717 | 81986901 | 81987029 | In-frame |
| ENST00000370728 | 81986901 | 81987029 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000370728 | 81836885 | 81837057 | 5CDS-5UTR |
| ENST00000370717 | 81907017 | 81907230 | Frame-shift |
| ENST00000370728 | 81907017 | 81907230 | Frame-shift |
| ENST00000370717 | 81952987 | 81953025 | In-frame |
| ENST00000370728 | 81952987 | 81953025 | In-frame |
| ENST00000370717 | 81986901 | 81987029 | In-frame |
| ENST00000370728 | 81986901 | 81987029 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000370728 | 81836885 | 81837057 | 5CDS-5UTR |
| ENST00000370717 | 81952987 | 81953025 | In-frame |
| ENST00000370728 | 81952987 | 81953025 | In-frame |
| ENST00000370717 | 81966058 | 81966183 | In-frame |
| ENST00000370728 | 81966058 | 81966183 | In-frame |
| ENST00000370717 | 81986901 | 81987029 | In-frame |
| ENST00000370728 | 81986901 | 81987029 | In-frame |
Top |
Infer the effects of exon skipping event on protein functional features for ADGRL2 |
p-ENSG00000117114_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000370717 | 5890 | 1459 | 81952987 | 81953025 | 2000 | 2037 | 594 | 607 |
| ENST00000370728 | 6319 | 1459 | 81952987 | 81953025 | 2429 | 2466 | 594 | 607 |
| ENST00000370717 | 5890 | 1459 | 81986901 | 81987029 | 3714 | 3841 | 1166 | 1208 |
| ENST00000370728 | 6319 | 1459 | 81986901 | 81987029 | 4143 | 4270 | 1166 | 1208 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000370717 | 5890 | 1459 | 81952987 | 81953025 | 2000 | 2037 | 594 | 607 |
| ENST00000370728 | 6319 | 1459 | 81952987 | 81953025 | 2429 | 2466 | 594 | 607 |
| ENST00000370717 | 5890 | 1459 | 81986901 | 81987029 | 3714 | 3841 | 1166 | 1208 |
| ENST00000370728 | 6319 | 1459 | 81986901 | 81987029 | 4143 | 4270 | 1166 | 1208 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000370717 | 5890 | 1459 | 81952987 | 81953025 | 2000 | 2037 | 594 | 607 |
| ENST00000370728 | 6319 | 1459 | 81952987 | 81953025 | 2429 | 2466 | 594 | 607 |
| ENST00000370717 | 5890 | 1459 | 81966058 | 81966183 | 2223 | 2347 | 669 | 710 |
| ENST00000370728 | 6319 | 1459 | 81966058 | 81966183 | 2652 | 2776 | 669 | 710 |
| ENST00000370717 | 5890 | 1459 | 81986901 | 81987029 | 3714 | 3841 | 1166 | 1208 |
| ENST00000370728 | 6319 | 1459 | 81986901 | 81987029 | 4143 | 4270 | 1166 | 1208 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O95490 | 594 | 607 | 595 | 607 | Alternative sequence | ID=VSP_010104;Note=In isoform 2%2C isoform 3%2C isoform 4 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 594 | 607 | 595 | 607 | Alternative sequence | ID=VSP_010104;Note=In isoform 2%2C isoform 3%2C isoform 4 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 594 | 607 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 594 | 607 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 594 | 607 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 594 | 607 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 1166 | 1208 | 1137 | 1459 | Alternative sequence | ID=VSP_010106;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3 |
| O95490 | 1166 | 1208 | 1137 | 1459 | Alternative sequence | ID=VSP_010106;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3 |
| O95490 | 1166 | 1208 | 1167 | 1209 | Alternative sequence | ID=VSP_010107;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 1166 | 1208 | 1167 | 1209 | Alternative sequence | ID=VSP_010107;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 1166 | 1208 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 1166 | 1208 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 1166 | 1208 | 1084 | 1459 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 1166 | 1208 | 1084 | 1459 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O95490 | 594 | 607 | 595 | 607 | Alternative sequence | ID=VSP_010104;Note=In isoform 2%2C isoform 3%2C isoform 4 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 594 | 607 | 595 | 607 | Alternative sequence | ID=VSP_010104;Note=In isoform 2%2C isoform 3%2C isoform 4 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 594 | 607 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 594 | 607 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 594 | 607 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 594 | 607 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 1166 | 1208 | 1137 | 1459 | Alternative sequence | ID=VSP_010106;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3 |
| O95490 | 1166 | 1208 | 1137 | 1459 | Alternative sequence | ID=VSP_010106;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3 |
| O95490 | 1166 | 1208 | 1167 | 1209 | Alternative sequence | ID=VSP_010107;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 1166 | 1208 | 1167 | 1209 | Alternative sequence | ID=VSP_010107;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 1166 | 1208 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 1166 | 1208 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 1166 | 1208 | 1084 | 1459 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 1166 | 1208 | 1084 | 1459 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O95490 | 594 | 607 | 595 | 607 | Alternative sequence | ID=VSP_010104;Note=In isoform 2%2C isoform 3%2C isoform 4 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 594 | 607 | 595 | 607 | Alternative sequence | ID=VSP_010104;Note=In isoform 2%2C isoform 3%2C isoform 4 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 594 | 607 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 594 | 607 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 594 | 607 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 594 | 607 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 669 | 710 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 669 | 710 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 669 | 710 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 669 | 710 | 26 | 851 | Topological domain | Note=Extracellular;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 1166 | 1208 | 1137 | 1459 | Alternative sequence | ID=VSP_010106;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3 |
| O95490 | 1166 | 1208 | 1137 | 1459 | Alternative sequence | ID=VSP_010106;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.3 |
| O95490 | 1166 | 1208 | 1167 | 1209 | Alternative sequence | ID=VSP_010107;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 1166 | 1208 | 1167 | 1209 | Alternative sequence | ID=VSP_010107;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10030676,ECO:0000303|Ref.3;Dbxref=PMID:10030676 |
| O95490 | 1166 | 1208 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 1166 | 1208 | 26 | 1459 | Chain | ID=PRO_0000012910;Note=Adhesion G protein-coupled receptor L2 |
| O95490 | 1166 | 1208 | 1084 | 1459 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| O95490 | 1166 | 1208 | 1084 | 1459 | Topological domain | Note=Cytoplasmic;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
Top |
3'-UTR located exon skipping events that lost miRNA binding sites in ADGRL2 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
Top |
SNVs in the skipped exons for ADGRL2 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
Top |
AD stage-associated exon skippint events for ADGRL2 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ADGRL2 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| CB | exon_skip_73456 | rs1022974 | chr1:82003925 | 2.864721e-04 | 3.929283e-02 |
Top |
Correlation with RNA binding proteins (RBPs) for ADGRL2 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| HCC | RBM5 | exon_skip_72550 | -4.607450e-01 | 3.164818e-14 |
| HCC | RBM5 | exon_skip_73328 | -5.120599e-01 | 5.597337e-18 |
| HCC | PABPN1 | exon_skip_283928 | -5.361204e-01 | 5.679671e-21 |
| HCC | RBMS2 | exon_skip_73456 | -4.743569e-01 | 2.488421e-16 |
| HCC | RBM6 | exon_skip_73456 | -4.116224e-01 | 2.666959e-12 |
| HCC | QKI | exon_skip_73456 | -4.471577e-01 | 1.759634e-14 |
| HCC | KHDRBS3 | exon_skip_73456 | -4.112673e-01 | 2.796017e-12 |
| HCC | RBM45 | exon_skip_73456 | -4.047122e-01 | 6.623672e-12 |
| IFG | PABPN1L | exon_skip_283928 | -5.989383e-01 | 7.585409e-04 |
| IFG | ELAVL4 | exon_skip_164916 | 6.177361e-01 | 7.723102e-04 |
| IFG | KHDRBS2 | exon_skip_164916 | 4.980304e-01 | 9.620167e-03 |
| IFG | KHDRBS3 | exon_skip_164916 | 4.517259e-01 | 2.052465e-02 |
| IFG | RBM24 | exon_skip_164916 | 4.843106e-01 | 1.216991e-02 |
| IFG | NOVA1 | exon_skip_164916 | 4.948566e-01 | 1.016635e-02 |
| IFG | RALYL | exon_skip_73456 | 4.428843e-01 | 2.346037e-02 |
| IFG | SRSF2 | exon_skip_282885 | 4.958272e-01 | 1.171562e-02 |
| IFG | RBM3 | exon_skip_282885 | 4.243744e-01 | 3.448574e-02 |
| PCC | RBMS2 | exon_skip_73456 | -6.478984e-01 | 1.142257e-25 |
| PCC | RBMS3 | exon_skip_73456 | -4.208983e-01 | 3.649783e-10 |
| PCC | RBM6 | exon_skip_73456 | -4.661007e-01 | 2.132180e-12 |
| PCC | PCBP4 | exon_skip_73456 | -4.010261e-01 | 2.781902e-09 |
| PCC | QKI | exon_skip_73456 | -4.905689e-01 | 9.456686e-14 |
| PCC | ZFP36 | exon_skip_73456 | -5.292304e-01 | 4.028891e-16 |
| PCC | PABPC1 | exon_skip_73456 | -4.853329e-01 | 1.881062e-13 |
| TC | RBM3 | exon_skip_194320 | 4.525323e-01 | 2.827861e-08 |
| TC | MBNL1 | exon_skip_194320 | 4.407346e-01 | 7.049068e-08 |
| TC | NUP42 | exon_skip_194320 | 7.344073e-01 | 1.756531e-24 |
| TC | ELAVL4 | exon_skip_164916 | 6.382582e-01 | 7.641989e-18 |
| TC | KHDRBS2 | exon_skip_164916 | 5.933669e-01 | 4.614606e-15 |
| TC | KHDRBS3 | exon_skip_164916 | 6.039072e-01 | 1.122701e-15 |
| TC | RBM24 | exon_skip_164916 | 5.955925e-01 | 3.438601e-15 |
| TC | NOVA1 | exon_skip_164916 | 4.740818e-01 | 1.947840e-09 |
| TC | RBMS2 | exon_skip_73456 | -5.935657e-01 | 3.605467e-15 |
| TC | SRSF2 | exon_skip_73456 | 5.663526e-01 | 1.132864e-13 |
| TC | MBNL1 | exon_skip_73456 | 4.183138e-01 | 1.643772e-07 |
| TC | HNRNPK | exon_skip_73456 | 4.008895e-01 | 5.829910e-07 |
| TC | KHDRBS3 | exon_skip_73456 | 7.549824e-01 | 5.450698e-28 |
| TC | HNRNPDL | exon_skip_73456 | 5.052664e-01 | 9.089944e-11 |
| TC | RBM45 | exon_skip_73456 | 6.230915e-01 | 5.817770e-17 |
| TC | NUP42 | exon_skip_73456 | 6.897988e-01 | 8.399613e-22 |
| TC | RALYL | exon_skip_73456 | 8.482550e-01 | 2.612076e-41 |
| TC | PTBP3 | exon_skip_73456 | 4.340373e-01 | 4.923951e-08 |
| TC | CELF1 | exon_skip_73456 | 5.582438e-01 | 2.980555e-13 |
| TC | NOVA1 | exon_skip_73456 | 7.866745e-01 | 9.412312e-32 |
Top |
RelatedDrugs for ADGRL2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ADGRL2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|