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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in RPSMAP, MSBB, and Mayo

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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3'-UTR located exon skipping events lost miRNA binding sites

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SNVs in the skipped exons with depth of coverage

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AD stage-associated exon skipping events

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Correlation with RNA binding proteins (RBPs)

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Related drugs with this gene

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Related diseases with this gene

Gene summary for MPRIP

check button Gene summary
Gene informationGene symbol

MPRIP

Gene ID

23164

Gene namemyosin phosphatase Rho interacting protein
SynonymsM-RIP|MRIP|RHOIP3|RIP3|p116Rip
Cytomap

17p11.2

Type of geneprotein-coding
Descriptionmyosin phosphatase Rho-interacting proteinRho interacting protein 3
Modification date20200313
UniProtAcc

A0A1W2PPU9,

A0A494BZV2,

A8MZF8,

B9EGI2,

H0Y2S9,

H0Y7E2,

H7C3G6,

J3KSK7,

J3KSW8,

J3QL44,

J3QRL2,

K7EJ14,

K7EL39,

Q6WCQ1,

Q96EE5,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Gene structures and expression levels for MPRIP

check buttonSkipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

ENSG00000133030
check button Differentially expressed gene analysis across multiple brain tissues between AD and control.
Tissue typeDEG directionBase mean exp.log2FC(AD/control)P-valueAdj. p-value

check button Differentially expressed isoform analysis across multiple brain tissues between AD and control.
gencode gene structure
Tissue typeDEG directionENSTTranscript info.Base mean exp.log2FC(AD/control)P-valueAdjc. p-value
CBDOWNENST00000579361.1MPRIP-214:protein_coding:MPRIP2.532765e+02-1.961082e+003.881018e-076.700939e-06
CBUPENST00000581989.1MPRIP-218:lncRNA:MPRIP1.199968e+001.056918e+001.109419e-048.079223e-04

check button Landscape of isoform expressions across multiple brain tissues between AD and control.
gencode gene structure

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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for MPRIP

check button Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap).
boxplot

check button All exon skipping events in AD cohorts.
Exon skip IDchrExons involved in exon skippingSkipped exon
exon_skip_107624chr1717173916:17174075:17176426:17176512:17177250:1717739617176426:17176512
exon_skip_127836chr1717137916:17138075:17142627:17142765:17146036:1714609217142627:17142765
exon_skip_133648chr1717150144:17150233:17154306:17154415:17158432:1715871517154306:17154415
exon_skip_139106chr1717172721:17172815:17173916:17174075:17176426:1717651217173916:17174075
exon_skip_157038chr1717173920:17174075:17176426:17176512:17177250:1717739617176426:17176512
exon_skip_157923chr1717174013:17174075:17175293:17175412:17176426:1717651217175293:17175412
exon_skip_165863chr1717161240:17161356:17164109:17167915:17171718:1717186517164109:17167915
exon_skip_166097chr1717173916:17174075:17175293:17175412:17176426:1717651217175293:17175412
exon_skip_172907chr1717147319:17147387:17150144:17150233:17154306:1715441517150144:17150233
exon_skip_189222chr1717161249:17161356:17164109:17167915:17171718:1717186517164109:17167915
exon_skip_203261chr1717042849:17042971:17075710:17075787:17078011:1707807617075710:17075787
exon_skip_220807chr1717161261:17161356:17164109:17167915:17171718:1717186517164109:17167915
exon_skip_225556chr1717142630:17142765:17143556:17143669:17146036:1714609217143556:17143669
exon_skip_230172chr1717180003:17180088:17180607:17180669:17184823:1718513017180607:17180669
exon_skip_239105chr1717142627:17142765:17143556:17143669:17146036:1714609217143556:17143669
exon_skip_263760chr1717161338:17161356:17164109:17167915:17171718:1717186517164109:17167915
exon_skip_272915chr1717078011:17078076:17126702:17126853:17131617:1713170117126702:17126853
exon_skip_29354chr1717154352:17154415:17158432:17159002:17161240:1716135617158432:17159002
exon_skip_70493chr1717173920:17174075:17175293:17175412:17176426:1717651217175293:17175412
exon_skip_76052chr1717180003:17180088:17180607:17180669:17184823:1718556017180607:17180669
exon_skip_86604chr1717131666:17131701:17136219:17136450:17137916:1713807517136219:17136450
exon_skip_89079chr1717075710:17075787:17078011:17078076:17126702:1712685317078011:17078076

check button Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control.
psi tcga
Exon skipping informationTissue typeAvg(PSIs) in ADAvg(PSIs) in controlDifference (PSI)Adj. p-value
exon_skip_165863MSBB_PG5.867883e-016.869643e-01-1.001760e-011.185139e-03


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Open reading frame (ORF) annotation in the exon skipping event for MPRIP

check button Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000034171217180607171806693UTR-3CDS
ENST000003417121712670217126853Frame-shift
ENST000003417121713621917136450Frame-shift
ENST000003417121707571017075787In-frame
ENST000003417121707801117078076In-frame
ENST000003417121714355617143669In-frame
ENST000003417121715014417150233In-frame
ENST000003417121717529317175412In-frame

check button Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000034171217180607171806693UTR-3CDS
ENST000003417121714355617143669In-frame
ENST000003417121715014417150233In-frame
ENST000003417121717529317175412In-frame

check button Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000034171217180607171806693UTR-3CDS
ENST000003417121712670217126853Frame-shift
ENST000003417121713621917136450Frame-shift
ENST000003417121715430617154415Frame-shift
ENST000003417121715843217159002Frame-shift
ENST000003417121707571017075787In-frame
ENST000003417121707801117078076In-frame
ENST000003417121714355617143669In-frame
ENST000003417121715014417150233In-frame
ENST000003417121717529317175412In-frame

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Infer the effects of exon skipping event on protein functional features for MPRIP

p-ENSG00000133030_img4.png
boxplot

check button Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003417123863102517075710170757871252014167
ENST000003417123863102517078011170780762032676789
ENST0000034171238631025171435561714366910371149345383
ENST0000034171238631025171501441715023312771365425455
ENST0000034171238631025171752931717541225912709863903

check button Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000034171238631025171435561714366910371149345383
ENST0000034171238631025171501441715023312771365425455
ENST0000034171238631025171752931717541225912709863903

check button Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003417123863102517075710170757871252014167
ENST000003417123863102517078011170780762032676789
ENST0000034171238631025171435561714366910371149345383
ENST0000034171238631025171501441715023312771365425455
ENST0000034171238631025171752931717541225912709863903

check button Lost protein functional features of individual exon skipping events in ROSMAP.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q6WCQ1416721025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1416743150DomainNote=PH 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ141672383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1678921025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1678943150DomainNote=PH 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ167892383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1345383346383Alternative sequenceID=VSP_051947;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q6WCQ134538321025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1345383348348Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q6WCQ1345383362362Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:24275569
Q6WCQ1345383365365Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:24275569
Q6WCQ13453832383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1345383352352Sequence conflictNote=P->S;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q6WCQ142545521025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1425455387483DomainNote=PH 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ186390321025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1863903673977Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q6WCQ1863903891891Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:23186163,PMID
Q6WCQ1863903824879RegionNote=Interaction with PPP1R12A

check button Lost protein functional features of individual exon skipping events in MSBB.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q6WCQ1345383346383Alternative sequenceID=VSP_051947;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q6WCQ134538321025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1345383348348Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q6WCQ1345383362362Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:24275569
Q6WCQ1345383365365Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:24275569
Q6WCQ13453832383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1345383352352Sequence conflictNote=P->S;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q6WCQ142545521025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1425455387483DomainNote=PH 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ186390321025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1863903673977Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q6WCQ1863903891891Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:23186163,PMID
Q6WCQ1863903824879RegionNote=Interaction with PPP1R12A

check button Lost protein functional features of individual exon skipping events in Mayo.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q6WCQ1416721025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1416743150DomainNote=PH 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ141672383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1678921025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1678943150DomainNote=PH 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ167892383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1345383346383Alternative sequenceID=VSP_051947;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q6WCQ134538321025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1345383348348Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q6WCQ1345383362362Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:24275569
Q6WCQ1345383365365Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:24275569
Q6WCQ13453832383RegionNote=Interaction with F-actin;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q6WCQ1345383352352Sequence conflictNote=P->S;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q6WCQ142545521025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1425455387483DomainNote=PH 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00145
Q6WCQ186390321025ChainID=PRO_0000223930;Note=Myosin phosphatase Rho-interacting protein
Q6WCQ1863903673977Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q6WCQ1863903891891Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:18669648,PMID:20068231,PMID:23186163,PMID
Q6WCQ1863903824879RegionNote=Interaction with PPP1R12A


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3'-UTR located exon skipping events that lost miRNA binding sites in MPRIP

check button 3'-UTR exon skipping evnets lost miRNA binding.
Tissue typeENSTExon skip startExon skip endmicroRNABinding site by TargetScanBinding type by TargetScanBdinding site by miRandaScore of miRandaEnergy by miRanda

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SNVs in the skipped exons for MPRIP

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Depth of Coverage in the skipped exon of the mutated samples.

check button - Sashimi plot in the skipped exon of the mutated samples.

check button - Non-synonymous mutations located in the skipped exons.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

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AD stage-associated exon skippint events for MPRIP

check button Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR).
AD stage infoCohortTissueSE idCoefficient P-valueChromosomeStrandE1 startE1 endSkipped startSkipped endE2 startE2 end

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MPRIP

check button sQTL information located at the skipped exons.
Tissue typeExon skip IDSNP idLocationP-valueFDR

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Correlation with RNA binding proteins (RBPs) for MPRIP

check button Correlated RBP and related information.
Tissue typeRBP nameExon skip IDCorrelation coeifficientP-value
CBSAMD4Aexon_skip_239105-4.683113e-014.817926e-10
CBCNOT4exon_skip_239105-4.957226e-013.057765e-11
CBFXR2exon_skip_239105-4.125432e-016.533424e-08
CBPCBP1exon_skip_239105-5.138553e-014.294035e-12
CBPCBP4exon_skip_2391054.364730e-018.852616e-09
CBEIF4G2exon_skip_239105-5.094754e-016.972945e-12
CBRBM4Bexon_skip_239105-4.417079e-015.597967e-09
CBDAZAP1exon_skip_1658634.821729e-011.231868e-10
CBTARDBPexon_skip_1658635.119402e-015.312484e-12
CBRBFOX2exon_skip_1658635.333441e-014.556427e-13
CBRBM25exon_skip_1658634.938160e-013.733969e-11
CBZNF326exon_skip_1658634.476239e-013.303711e-09
CBELAVL1exon_skip_1658635.122814e-015.115346e-12
CBSRSF11exon_skip_1658634.297915e-011.571339e-08
CBSAMD4Aexon_skip_1658634.465526e-013.637481e-09
CBCNOT4exon_skip_1658634.815109e-011.316620e-10
CBRBM5exon_skip_1658634.565855e-011.457576e-09
CBFXR2exon_skip_1658634.502130e-012.614481e-09
CBRC3H1exon_skip_1658634.951812e-013.236653e-11
CBANKHD1exon_skip_1658634.590788e-011.155896e-09
CBG3BP2exon_skip_1658634.549225e-011.699632e-09
CBKHDRBS2exon_skip_1658634.263731e-012.097462e-08
CBSF1exon_skip_1658635.278214e-018.730616e-13
CBFUBP1exon_skip_1658634.832244e-011.108010e-10
CBHNRNPA0exon_skip_1658634.120026e-016.823118e-08
CBPUM1exon_skip_1658634.887845e-016.289112e-11
CBPPRC1exon_skip_1658634.337015e-011.124854e-08
CBHNRNPA2B1exon_skip_1658634.630103e-017.988404e-10
CBEIF4G2exon_skip_1658634.551530e-011.663913e-09
CBPTBP1exon_skip_1658634.383114e-017.543240e-09
CBPTBP3exon_skip_1658634.206407e-013.380021e-08
CBHNRNPLexon_skip_1658634.357049e-019.462236e-09
CBCELF1exon_skip_1658635.710611e-013.848952e-15
CBRBM23exon_skip_1658634.266224e-012.053959e-08
CBEWSR1exon_skip_1658635.012617e-011.699335e-11
CBSRSF1exon_skip_1658635.350975e-013.697290e-13
CBSRSF4exon_skip_1658634.470147e-013.489705e-09
CBSRSF5exon_skip_1658634.460399e-013.808511e-09
CBRBM41exon_skip_1658634.235237e-012.661843e-08
CBPCBP4exon_skip_760525.401944e-012.000372e-13
DLPFCSRSF2exon_skip_760524.119329e-011.757965e-15
DLPFCPCBP4exon_skip_760524.497114e-011.764565e-18
DLPFCCELF1exon_skip_760524.417698e-018.098427e-18
DLPFCSRSF9exon_skip_760524.203503e-014.065198e-16
DLPFCDAZAP1exon_skip_1892226.238777e-011.008099e-27
DLPFCTARDBPexon_skip_1892225.436392e-013.634756e-20
DLPFCSRSF2exon_skip_1892226.445858e-014.781758e-30
DLPFCRBFOX2exon_skip_1892227.609221e-012.316232e-47
DLPFCELAVL4exon_skip_1892227.156596e-011.360933e-39
DLPFCELAVL1exon_skip_1892225.170661e-014.397889e-18
DLPFCSFPQexon_skip_1892225.580415e-012.250530e-21
DLPFCSRSF11exon_skip_189222-4.545543e-017.632519e-14
DLPFCCNOT4exon_skip_1892225.592186e-011.782129e-21
DLPFCRBM5exon_skip_1892225.996774e-013.221771e-25
DLPFCRBM3exon_skip_1892226.221070e-011.563834e-27
DLPFCMBNL1exon_skip_1892225.035173e-014.335036e-17
DLPFCTRNAU1APexon_skip_1892224.269211e-013.147223e-12
DLPFCFXR2exon_skip_1892226.848446e-014.047963e-35
DLPFCPCBP1exon_skip_1892226.398433e-011.688630e-29
DLPFCILF2exon_skip_1892226.077456e-014.976012e-26
DLPFCHNRNPKexon_skip_1892225.923822e-011.667665e-24
DLPFCPCBP4exon_skip_1892224.441081e-013.239861e-13
DLPFCUNKexon_skip_1892226.191056e-013.270782e-27
DLPFCTRA2Aexon_skip_1892224.010295e-017.651505e-11
DLPFCPCBP2exon_skip_1892225.907962e-012.371079e-24
DLPFCRC3H1exon_skip_1892225.171260e-014.352648e-18
DLPFCANKHD1exon_skip_1892224.367152e-018.751475e-13
DLPFCG3BP2exon_skip_1892227.283517e-011.300224e-41
DLPFCKHDRBS2exon_skip_1892227.704312e-013.233384e-49
DLPFCSNRPAexon_skip_1892225.361206e-011.473995e-19
DLPFCSF1exon_skip_1892226.764385e-015.406912e-34
DLPFCKHDRBS3exon_skip_1892226.689175e-015.116149e-33
DLPFCHNRNPA1exon_skip_1892226.206313e-012.249993e-27
DLPFCRBM24exon_skip_1892225.860563e-016.710428e-24
DLPFCENOX1exon_skip_1892226.505888e-019.374384e-31
DLPFCHNRNPA0exon_skip_1892227.551955e-012.758826e-46
DLPFCPUM1exon_skip_1892225.993766e-013.450661e-25
DLPFCPPRC1exon_skip_1892226.420685e-019.367686e-30
DLPFCHNRNPA1L2exon_skip_1892225.436782e-013.608129e-20
DLPFCHNRNPA2B1exon_skip_1892224.590743e-014.020560e-14
DLPFCHNRNPDLexon_skip_1892226.301845e-012.062069e-28
DLPFCRBM45exon_skip_1892224.122158e-011.993220e-11
DLPFCHNRNPABexon_skip_1892225.820497e-011.595641e-23
DLPFCNUP42exon_skip_1892226.320536e-011.279359e-28
DLPFCRALYLexon_skip_1892226.497200e-011.189474e-30
DLPFCEIF4G2exon_skip_1892225.900835e-012.775615e-24
DLPFCRBM42exon_skip_1892226.131719e-011.374471e-26
DLPFCPTBP3exon_skip_1892225.607423e-011.315667e-21
DLPFCHNRNPLexon_skip_1892226.934228e-012.621932e-36
DLPFCCELF1exon_skip_1892225.861794e-016.533027e-24
DLPFCRBM23exon_skip_1892226.181979e-014.082150e-27
DLPFCEWSR1exon_skip_1892226.699806e-013.738755e-33
DLPFCSRSF1exon_skip_1892226.047102e-011.011061e-25
DLPFCFUSexon_skip_1892226.410010e-011.243542e-29
DLPFCSRSF4exon_skip_1892225.092020e-011.680423e-17
DLPFCSRSF9exon_skip_1892226.403236e-011.487555e-29
DLPFCSRSF5exon_skip_1892225.785580e-013.361772e-23
DLPFCHNRNPH2exon_skip_1892226.906968e-016.321641e-36
DLPFCYBX2exon_skip_1892226.292075e-012.643020e-28
DLPFCEIF4Bexon_skip_1892226.255737e-016.602539e-28
DLPFCESRP1exon_skip_1892225.423647e-014.619781e-20
DLPFCNOVA1exon_skip_1892226.528718e-014.995821e-31
DLPFCZC3H10exon_skip_1892224.997376e-018.061906e-17
DLPFCRBM4Bexon_skip_1892224.293049e-012.313550e-12
FLSRSF2exon_skip_1658636.073691e-012.387466e-21
FLRBFOX2exon_skip_1658635.107118e-011.507360e-14
FLMSI1exon_skip_165863-5.786460e-014.324273e-19
FLELAVL4exon_skip_1658636.494737e-014.189969e-25
FLSAMD4Aexon_skip_165863-4.074212e-012.567393e-09
FLRBM3exon_skip_1658634.219741e-015.951089e-10
FLMBNL1exon_skip_1658634.154651e-011.154291e-09
FLFXR2exon_skip_1658635.516940e-013.647415e-17
FLILF2exon_skip_1658635.012579e-015.411995e-14
FLHNRNPKexon_skip_1658635.373412e-013.302231e-16
FLG3BP2exon_skip_1658636.323259e-011.665466e-23
FLKHDRBS2exon_skip_1658634.182370e-018.720411e-10
FLKHDRBS3exon_skip_1658635.965420e-011.801529e-20
FLRBM24exon_skip_1658635.685661e-012.381629e-18
FLFUBP1exon_skip_1658634.451881e-014.978806e-11
FLHNRNPA0exon_skip_1658635.808268e-012.966394e-19
FLRBM45exon_skip_1658634.567671e-011.344220e-11
FLRALYLexon_skip_1658636.490862e-014.565514e-25
FLHNRNPLexon_skip_1658634.964654e-011.019312e-13
FLCELF1exon_skip_1658634.109545e-011.811873e-09
FLRBM23exon_skip_1658634.433574e-016.096618e-11
FLSRSF1exon_skip_1658634.549843e-011.649780e-11
FLSRSF9exon_skip_1658635.199714e-014.145669e-15
FLHNRNPH2exon_skip_1658634.555990e-011.537492e-11
FLEIF4Bexon_skip_1658634.637681e-015.944697e-12
FLESRP1exon_skip_1658634.821353e-016.387486e-13
FLNOVA1exon_skip_1658635.090344e-011.896575e-14
HCCDAZAP1exon_skip_165863-6.833445e-016.677256e-39
HCCTARDBPexon_skip_165863-5.073744e-012.885774e-19
HCCRBMS3exon_skip_165863-5.494674e-016.182121e-23
HCCMSI1exon_skip_165863-6.328586e-015.899992e-32
HCCPABPN1exon_skip_165863-6.149803e-018.574682e-30
HCCELAVL4exon_skip_165863-4.214203e-013.526716e-13
HCCRBM25exon_skip_165863-5.582447e-019.100134e-24
HCCZNF326exon_skip_165863-7.576554e-013.833960e-52
HCCELAVL1exon_skip_165863-4.001124e-016.433323e-12
HCCSFPQexon_skip_165863-6.916045e-013.565405e-40
HCCZNF638exon_skip_165863-6.636787e-014.911579e-36
HCCRBM6exon_skip_165863-7.354913e-019.988535e-48
HCCSRSF11exon_skip_165863-6.668647e-011.744385e-36
HCCSAMD4Aexon_skip_165863-6.643686e-013.929542e-36
HCCCNOT4exon_skip_165863-5.506033e-014.839750e-23
HCCRBM5exon_skip_165863-6.866974e-012.056758e-39
HCCMBNL1exon_skip_165863-4.594736e-011.154306e-15
HCCIGF2BP2exon_skip_165863-5.298151e-013.697669e-21
HCCTRNAU1APexon_skip_165863-6.284855e-012.054916e-31
HCCRBM47exon_skip_165863-4.215986e-013.439040e-13
HCCPCBP1exon_skip_165863-5.459854e-011.301662e-22
HCCPCBP4exon_skip_165863-6.130803e-011.428699e-29
HCCUNKexon_skip_165863-6.304028e-011.191941e-31
HCCTRA2Aexon_skip_165863-5.802911e-015.710583e-26
HCCPCBP2exon_skip_165863-5.595981e-016.738117e-24
HCCRC3H1exon_skip_165863-4.152381e-018.365521e-13
HCCANKHD1exon_skip_165863-6.800841e-012.067131e-38
HCCSNRPAexon_skip_165863-4.618947e-017.824861e-16
HCCSF1exon_skip_165863-6.083598e-015.004645e-29
HCCKHDRBS3exon_skip_165863-6.366009e-011.995898e-32
HCCFUBP1exon_skip_165863-6.114985e-012.179720e-29
HCCENOX1exon_skip_165863-5.088012e-012.208337e-19
HCCPPRC1exon_skip_165863-4.511065e-014.321614e-15
HCCHNRNPA1L2exon_skip_165863-5.041692e-015.239856e-19
HCCHNRNPA2B1exon_skip_165863-6.577640e-013.246240e-35
HCCRBM45exon_skip_165863-6.556159e-016.377992e-35
HCCHNRNPABexon_skip_165863-5.854360e-011.653447e-26
HCCEIF4G2exon_skip_165863-6.820155e-011.060290e-38
HCCRBM42exon_skip_165863-4.818428e-012.820118e-17
HCCPTBP1exon_skip_165863-7.762006e-013.206959e-56
HCCHNRNPLexon_skip_165863-4.092608e-011.896435e-12
HCCPABPC5exon_skip_165863-4.994516e-011.246498e-18
HCCEWSR1exon_skip_165863-4.961282e-012.276979e-18
HCCSRSF1exon_skip_165863-5.002592e-011.075660e-18
HCCSRSF4exon_skip_165863-6.470315e-018.979946e-34
HCCSRSF5exon_skip_165863-4.832845e-012.199225e-17
HCCRBM41exon_skip_165863-5.533138e-012.688502e-23
HCCHNRNPFexon_skip_165863-6.856244e-013.003267e-39
HCCRBM4exon_skip_165863-6.099556e-013.283594e-29
HCCZC3H10exon_skip_165863-6.729144e-012.357779e-37
HCCRBM4Bexon_skip_165863-6.714230e-013.878585e-37
HCCPCBP4exon_skip_760525.644065e-012.290977e-24
IFGDAZAP1exon_skip_165863-4.686843e-011.188069e-02
IFGRBFOX2exon_skip_1658634.449969e-011.765258e-02
IFGELAVL4exon_skip_1658634.592807e-011.394782e-02
IFGPABPN1Lexon_skip_165863-4.040279e-013.298207e-02
IFGIGF2BP3exon_skip_165863-4.391090e-011.939913e-02
IFGFXR2exon_skip_1658634.774756e-011.018562e-02
IFGRBM47exon_skip_165863-4.377251e-011.982962e-02
IFGPCBP4exon_skip_165863-4.219230e-012.532495e-02
IFGG3BP2exon_skip_1658636.045914e-016.551107e-04
IFGKHDRBS2exon_skip_1658634.655986e-011.252879e-02
IFGKHDRBS3exon_skip_1658635.095489e-015.611504e-03
IFGRALYLexon_skip_1658635.345456e-013.385191e-03
IFGPTBP1exon_skip_165863-4.627777e-011.314677e-02
IFGESRP2exon_skip_165863-4.443693e-011.783235e-02
IFGEWSR1exon_skip_760524.954657e-017.341049e-03
PCCRBMS3exon_skip_263760-4.730301e-012.189416e-13
PCCRBFOX2exon_skip_2637605.580520e-015.348282e-19
PCCMSI1exon_skip_263760-4.673295e-014.610067e-13
PCCPABPN1exon_skip_263760-4.384872e-011.625431e-11
PCCELAVL4exon_skip_2637604.091847e-014.370056e-10
PCCZNF326exon_skip_263760-6.786369e-012.271113e-30
PCCSFPQexon_skip_263760-5.202364e-012.622406e-16
PCCZNF638exon_skip_263760-4.861486e-013.741072e-14
PCCRBM6exon_skip_263760-6.093943e-013.010892e-23
PCCSRSF11exon_skip_263760-4.958069e-019.699513e-15
PCCSAMD4Aexon_skip_263760-6.721320e-011.281245e-29
PCCIGF2BP2exon_skip_263760-4.810676e-017.483262e-14
PCCTRNAU1APexon_skip_263760-5.576405e-015.745815e-19
PCCPCBP4exon_skip_263760-5.134022e-017.414305e-16
PCCTRA2Aexon_skip_263760-5.189335e-013.202831e-16
PCCANKHD1exon_skip_263760-4.008955e-011.048255e-09
PCCG3BP2exon_skip_2637605.105682e-011.133183e-15
PCCHNRNPA2B1exon_skip_263760-5.201999e-012.637142e-16
PCCPTBP1exon_skip_263760-8.080590e-017.572410e-51
PCCSRSF4exon_skip_263760-5.099709e-011.238528e-15
PCCHNRNPFexon_skip_263760-6.768379e-013.681015e-30
PCCRBM4exon_skip_263760-4.858637e-013.890584e-14
PCCRBM4Bexon_skip_263760-4.417285e-011.107251e-11
PGSRSF2exon_skip_1658634.857959e-017.997263e-13
PGRBFOX2exon_skip_1658637.478153e-018.086604e-36
PGMSI1exon_skip_165863-4.738189e-013.408908e-12
PGELAVL4exon_skip_1658637.705639e-013.238746e-39
PGRBM25exon_skip_1658634.426753e-011.147942e-10
PGELAVL1exon_skip_1658634.721921e-014.133052e-12
PGSRSF11exon_skip_1658634.376673e-011.956237e-10
PGSAMD4Aexon_skip_165863-4.475801e-016.753156e-11
PGRBM3exon_skip_1658634.443184e-019.619264e-11
PGMBNL1exon_skip_1658634.351879e-012.538895e-10
PGIGF2BP2exon_skip_165863-4.121731e-012.588302e-09
PGFXR2exon_skip_1658636.771087e-013.076444e-27
PGPCBP1exon_skip_1658635.388911e-016.246061e-16
PGILF2exon_skip_1658635.726603e-013.280497e-18
PGHNRNPKexon_skip_1658635.656330e-011.027727e-17
PGG3BP2exon_skip_1658637.218477e-012.327338e-32
PGKHDRBS2exon_skip_1658636.542368e-015.910360e-25
PGKHDRBS3exon_skip_1658637.050086e-012.553272e-30
PGRBM24exon_skip_1658636.127357e-012.798434e-21
PGFUBP1exon_skip_1658634.018701e-016.923726e-09
PGENOX1exon_skip_1658634.663836e-018.154370e-12
PGHNRNPA0exon_skip_1658636.025161e-011.864951e-20
PGPUM1exon_skip_1658636.250365e-012.599489e-22
PGHNRNPDLexon_skip_1658634.453213e-018.631257e-11
PGRBM45exon_skip_1658634.361178e-012.302963e-10
PGNUP42exon_skip_1658634.892181e-015.229722e-13
PGRALYLexon_skip_1658637.337816e-016.723248e-34
PGEIF4G2exon_skip_1658634.503074e-015.009454e-11
PGPTBP1exon_skip_165863-4.348888e-012.619639e-10
PGHNRNPLexon_skip_1658635.853881e-013.863084e-19
PGCELF1exon_skip_1658635.788957e-011.163767e-18
PGRBM23exon_skip_1658634.467229e-017.413851e-11
PGSRSF1exon_skip_1658634.149780e-011.968572e-09
PGSRSF9exon_skip_1658634.767411e-012.405645e-12
PGHNRNPH2exon_skip_1658636.588907e-012.104210e-25
PGEIF4Bexon_skip_1658634.258198e-016.672312e-10
PGZCRB1exon_skip_1658634.008007e-017.653650e-09
PGNOVA1exon_skip_1658635.829350e-015.876930e-19
PGRBM4exon_skip_1658634.898220e-014.849722e-13
STGRBFOX2exon_skip_1658635.555065e-017.493309e-09
STGMSI1exon_skip_165863-4.901120e-016.148744e-07
STGELAVL4exon_skip_1658636.668089e-012.950706e-13
STGIGF2BP2exon_skip_165863-5.334305e-013.685577e-08
STGFXR2exon_skip_1658634.000629e-017.092862e-05
STGPCBP1exon_skip_1658634.908111e-015.893486e-07
STGG3BP2exon_skip_1658635.751766e-011.638319e-09
STGKHDRBS2exon_skip_1658635.531209e-018.950884e-09
STGKHDRBS3exon_skip_1658635.126414e-011.493697e-07
STGRBM24exon_skip_1658634.089955e-014.693402e-05
STGHNRNPA0exon_skip_1658636.356358e-017.655843e-12
STGRBM45exon_skip_1658634.200552e-012.768793e-05
STGNUP42exon_skip_1658634.574710e-014.024760e-06
STGRALYLexon_skip_1658636.304233e-011.273502e-11
STGPTBP1exon_skip_165863-4.033346e-016.105607e-05
STGSRSF9exon_skip_1658634.044943e-015.787509e-05
STGHNRNPH2exon_skip_1658635.805012e-011.066796e-09
STGNOVA1exon_skip_1658635.511453e-011.035944e-08
TCSRSF2exon_skip_2208074.832241e-019.671439e-11
TCRBFOX2exon_skip_2208078.245230e-016.436405e-41
TCELAVL4exon_skip_2208077.745452e-013.024552e-33
TCRBM25exon_skip_2208075.096839e-015.845378e-12
TCSRSF11exon_skip_2208074.083091e-018.335276e-08
TCCNOT4exon_skip_2208074.599522e-019.430110e-10
TCMBNL1exon_skip_2208074.537906e-011.675654e-09
TCFXR2exon_skip_2208074.977825e-012.127684e-11
TCILF2exon_skip_2208074.793707e-011.427006e-10
TCHNRNPKexon_skip_2208074.142960e-015.147903e-08
TCG3BP2exon_skip_2208077.053997e-012.160117e-25
TCKHDRBS2exon_skip_2208077.903339e-011.927618e-35
TCKHDRBS3exon_skip_2208077.014055e-015.229716e-25
TCRBM24exon_skip_2208077.079779e-011.211098e-25
TCHNRNPA0exon_skip_2208076.908805e-015.017715e-24
TCPUM1exon_skip_2208076.816528e-013.370081e-23
TCPPRC1exon_skip_2208074.216524e-012.810691e-08
TCHNRNPDLexon_skip_2208074.511631e-012.133772e-09
TCRBM45exon_skip_2208074.291003e-011.500534e-08
TCNUP42exon_skip_2208076.467968e-012.488680e-20
TCRALYLexon_skip_2208077.503238e-013.339918e-30
TCEIF4G2exon_skip_2208074.298650e-011.405682e-08
TCPTBP3exon_skip_2208075.739694e-012.119359e-15
TCCELF1exon_skip_2208076.750552e-011.260840e-22
TCEWSR1exon_skip_2208074.020457e-011.366257e-07
TCSRSF9exon_skip_2208074.159577e-014.495871e-08
TCSRSF5exon_skip_2208074.746084e-012.292613e-10
TCHNRNPH2exon_skip_2208076.603030e-012.136914e-21
TCYBX2exon_skip_2208074.324600e-011.124918e-08
TCESRP1exon_skip_2208076.239341e-011.211656e-18
TCNOVA1exon_skip_2208075.154328e-013.075467e-12
TCZNF326exon_skip_157923-4.449756e-013.739743e-09

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RelatedDrugs for MPRIP

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MPRIP

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource