|
||||||
|
 | |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| 3'-UTR located exon skipping events lost miRNA binding sites |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| |
| |
|
Gene summary for MAST2 |
 Gene summary |
| Gene information | Gene symbol | MAST2 | Gene ID | 23139 |
| Gene name | microtubule associated serine/threonine kinase 2 | |
| Synonyms | MAST205|MTSSK | |
| Cytomap | 1p34.1 | |
| Type of gene | protein-coding | |
| Description | microtubule-associated serine/threonine-protein kinase 2microtubule associated testis specific serine/threonine protein kinase | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
Gene structures and expression levels for MAST2 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
ENSG00000086015
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | DOWN | ENST00000372009.3 | MAST2-203:protein_coding:MAST2 | 2.297158e+02 | -1.149250e+00 | 2.802099e-09 | 1.036553e-07 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
 |
Top |
Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for MAST2 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
 |
| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_101385 | chr1 | 45882367:45882395:45959386:45959477:45997724:45997799 | 45959386:45959477 |
| exon_skip_105484 | chr1 | 46023772:46023980:46025677:46025815:46027731:46027863 | 46025677:46025815 |
| exon_skip_123691 | chr1 | 45997724:45997799:46002805:46002883:46006241:46006395 | 46002805:46002883 |
| exon_skip_160608 | chr1 | 46027731:46027863:46028768:46028933:46029466:46029567 | 46028768:46028933 |
| exon_skip_168131 | chr1 | 46029831:46029953:46030129:46030238:46030607:46030759 | 46030129:46030238 |
| exon_skip_197703 | chr1 | 46008296:46008371:46010730:46010939:46019596:46019697 | 46010730:46010939 |
| exon_skip_295037 | chr1 | 45829439:45829581:45882364:45882395:45959386:45959477 | 45882364:45882395 |
| exon_skip_49957 | chr1 | 46008296:46008371:46010730:46010939:46019596:46019692 | 46010730:46010939 |
| exon_skip_8414 | chr1 | 45882364:45882395:45959386:45959477:45997724:45997799 | 45959386:45959477 |
| exon_skip_89306 | chr1 | 46010730:46010939:46019596:46019697:46021950:46022082 | 46019596:46019697 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
 |