ExonSkipAD Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
leaf

Gene summary

leaf

Gene structures and expression levels

leaf

Exon skipping events with PSIs in RPSMAP, MSBB, and Mayo

leaf

Open reading frame (ORF) annotation in the exon skipping event

leaf

Exon skipping events in the canonical protein sequence

leaf

3'-UTR located exon skipping events lost miRNA binding sites

leaf

SNVs in the skipped exons with depth of coverage

leaf

AD stage-associated exon skipping events

leaf

Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

leaf

Correlation with RNA binding proteins (RBPs)

leaf

Related drugs with this gene

leaf

Related diseases with this gene

Gene summary for EPB41L3

check button Gene summary
Gene informationGene symbol

EPB41L3

Gene ID

23136

Gene nameerythrocyte membrane protein band 4.1 like 3
Synonyms4.1B|DAL-1|DAL1
Cytomap

18p11.31

Type of geneprotein-coding
Descriptionband 4.1-like protein 3differentially expressed in adenocarcinoma of the lung protein 1
Modification date20200320
UniProtAcc

A0A0A0MRA8,

A0A0A0MSA4,

A0A0J9YW26,

A0A0J9YW31,

A0A0J9YWE1,

A0A0J9YWN0,

A0A0J9YWS4,

A0A0J9YY18,

A0A0U1RR92,

A0A1B0GTF8,

A8K968,

J3KRD1,

J3KS70,

J3KT37,

J3QKK4,

J3QKY2,

J3QLU5,

J3QR33,

J3QRQ6,

J3QS55,

J3QS83,

Q8NFG9,

Q96HL7,

Q9Y2J2,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

Top

Gene structures and expression levels for EPB41L3

check buttonSkipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

ENSG00000082397
check button Differentially expressed gene analysis across multiple brain tissues between AD and control.
Tissue typeDEG directionBase mean exp.log2FC(AD/control)P-valueAdj. p-value

check button Differentially expressed isoform analysis across multiple brain tissues between AD and control.
gencode gene structure
Tissue typeDEG directionENSTTranscript info.Base mean exp.log2FC(AD/control)P-valueAdjc. p-value
STGUPENST00000578524.5EPB41L3-213:protein_coding:EPB41L31.536612e+016.368584e+004.873739e-073.146248e-04
PGDOWNENST00000582592.1EPB41L3-228:protein_coding:EPB41L32.313080e+00-8.320980e-012.193348e-044.875055e-03
PGDOWNENST00000579271.5EPB41L3-215:protein_coding:EPB41L31.163227e+00-9.405775e-014.476991e-034.229616e-02
CBUPENST00000637651.1EPB41L3-236:nonsense_mediated_decay:EPB41L31.660855e+038.422394e-019.748723e-092.944142e-07
CBUPENST00000400111.8EPB41L3-203:protein_coding:EPB41L33.382291e+029.164812e-013.349554e-064.191438e-05
TCDOWNENST00000580647.5EPB41L3-220:protein_coding:EPB41L32.794298e+00-8.831767e-019.960530e-049.874104e-03
TCDOWNENST00000578524.5EPB41L3-213:protein_coding:EPB41L35.277074e+01-1.333073e+005.531618e-033.612702e-02

check button Landscape of isoform expressions across multiple brain tissues between AD and control.
gencode gene structure

Top

Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for EPB41L3

check button Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap).
boxplot

check button All exon skipping events in AD cohorts.
Exon skip IDchrExons involved in exon skippingSkipped exon
exon_skip_100658chr185396201:5396332:5397058:5397426:5406777:54069685397058:5397426
exon_skip_102827chr185393103:5393478:5395067:5395147:5395609:53957075395067:5395147
exon_skip_136359chr185410566:5410619:5415818:5416378:5419711:54197945415818:5416378
exon_skip_163113chr185395609:5395707:5396201:5396332:5397058:53974265396201:5396332
exon_skip_185954chr185393273:5393478:5394677:5394793:5395067:53951475394677:5394793
exon_skip_197303chr185398021:5398143:5400497:5400595:5406777:54069685400497:5400595
exon_skip_197366chr185398651:5399385:5400969:5401043:5406777:54069685400969:5401043
exon_skip_198698chr185397398:5397426:5398021:5398143:5406777:54069685398021:5398143
exon_skip_211018chr185428313:5428465:5433469:5433556:5433903:54341215433469:5433556
exon_skip_212145chr185395067:5395147:5395609:5395707:5396201:53963325395609:5395707
exon_skip_212999chr185393455:5393478:5394677:5394793:5395067:53951475394677:5394793
exon_skip_214821chr185489125:5489194:5539621:5539698:5540340:55403965539621:5539698
exon_skip_230493chr185433903:5434121:5438035:5438110:5443838:54438805438035:5438110
exon_skip_233037chr185406848:5406968:5407701:5407736:5410566:54106195407701:5407736
exon_skip_240597chr185438035:5438110:5443838:5443880:5445140:54452445443838:5443880
exon_skip_250584chr185397398:5397426:5398021:5401043:5406777:54069685398021:5401043
exon_skip_258387chr185393296:5393478:5394677:5394793:5395067:53951475394677:5394793
exon_skip_268463chr185393103:5393478:5394677:5394793:5395067:53951475394677:5394793
exon_skip_294361chr185397398:5397426:5398021:5398143:5400969:54010435398021:5398143
exon_skip_295339chr185394677:5394793:5395067:5395147:5395609:53956975395067:5395147
exon_skip_46407chr185410566:5410619:5415818:5416378:5419711:54197455415818:5416378
exon_skip_52455chr185489001:5489194:5539621:5539698:5540340:55403965539621:5539698
exon_skip_60169chr185398113:5398143:5400969:5401043:5406765:54069685400969:5401043
exon_skip_65657chr185398113:5398143:5400969:5401043:5406777:54069685400969:5401043
exon_skip_7232chr185423378:5423553:5424262:5424359:5428313:54284655424262:5424359
exon_skip_73613chr185394677:5394793:5395067:5395147:5395609:53957075395067:5395147
exon_skip_75728chr185397398:5397426:5398021:5398143:5400497:54005955398021:5398143
exon_skip_7903chr185398113:5398143:5400497:5400595:5406777:54069685400497:5400595
exon_skip_90867chr185398113:5398143:5398651:5399385:5400969:54010435398651:5399385
exon_skip_96130chr185406848:5406968:5410566:5410619:5419711:54197945410566:5410619

check button Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control.
psi tcga
Exon skipping informationTissue typeAvg(PSIs) in ADAvg(PSIs) in controlDifference (PSI)Adj. p-value
exon_skip_198698MSBB_PG5.351145e-017.035714e-01-1.684569e-013.999252e-03
exon_skip_233037MSBB_PG5.840426e-017.607143e-01-1.766717e-014.303191e-06


Top

Open reading frame (ORF) annotation in the exon skipping event for EPB41L3

check button Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000341928539467753947935CDS-5UTR
ENST0000034192854242625424359Frame-shift
ENST0000034192854438385443880Frame-shift
ENST0000034192853950675395147In-frame
ENST0000034192853956095395707In-frame
ENST0000034192853962015396332In-frame
ENST0000034192853980215398143In-frame
ENST0000034192854077015407736In-frame
ENST0000034192854158185416378In-frame

check button Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000341928539467753947935CDS-5UTR
ENST0000034192854438385443880Frame-shift
ENST0000034192853950675395147In-frame
ENST0000034192853980215398143In-frame
ENST0000034192854077015407736In-frame
ENST0000034192854158185416378In-frame

check button Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST00000341928539467753947935CDS-5UTR
ENST0000034192854334695433556Frame-shift
ENST0000034192854380355438110Frame-shift
ENST0000034192854438385443880Frame-shift
ENST0000034192853950675395147In-frame
ENST0000034192853956095395707In-frame
ENST0000034192853962015396332In-frame
ENST0000034192853980215398143In-frame
ENST0000034192854077015407736In-frame
ENST0000034192854158185416378In-frame

Top

Infer the effects of exon skipping event on protein functional features for EPB41L3

p-ENSG00000082397_img4.png
boxplot

check button Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST00000341928472310875415818541637818482407502688
ENST00000341928472310875407701540773624632497707718
ENST00000341928472310875398021539814326912812783823
ENST00000341928472310875396201539633231833313947990
ENST000003419284723108753956095395707331534129911023
ENST0000034192847231087539506753951473414349310241050

check button Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST00000341928472310875415818541637818482407502688
ENST00000341928472310875407701540773624632497707718
ENST00000341928472310875398021539814326912812783823
ENST0000034192847231087539506753951473414349310241050

check button Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST00000341928472310875415818541637818482407502688
ENST00000341928472310875407701540773624632497707718
ENST00000341928472310875398021539814326912812783823
ENST00000341928472310875396201539633231833313947990
ENST000003419284723108753956095395707331534129911023
ENST0000034192847231087539506753951473414349310241050

check button Lost protein functional features of individual exon skipping events in ROSMAP.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q9Y2J2502688503689Alternative sequenceID=VSP_000483;Note=In isoform 2%2C isoform 3 and isoform 4. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:14702039,PMID:15489334,PMID:98921
Q9Y2J250268811087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J250268821087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2502688555555Natural variantID=VAR_048353;Note=A->T;Dbxref=dbSNP:rs9966357
Q9Y2J2502688575575Natural variantID=VAR_048354;Note=Y->C;Dbxref=dbSNP:rs8082898
Q9Y2J2502688394513RegionNote=Hydrophilic
Q9Y2J2502688514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2707718708719Alternative sequenceID=VSP_000484;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:15489334,PMID:9892180
Q9Y2J270771811087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J270771821087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2707718708708Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WV92
Q9Y2J2707718514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2783823784824Alternative sequenceID=VSP_000485;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:15489334,PMID:9892180
Q9Y2J278382311087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J278382321087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2783823514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J29479908351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J294799011087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J294799021087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2947990960960Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WV92
Q9Y2J2947990962962Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:24275569;Dbxref=PMID:16964243,PMID:24275569
Q9Y2J29479908611083RegionNote=C-terminal (CTD)
Q9Y2J299110238351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J2991102311087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J2991102321087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J299110238611083RegionNote=C-terminal (CTD)
Q9Y2J2102410508351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J21024105011087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J21024105021087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2102410508611083RegionNote=C-terminal (CTD)

check button Lost protein functional features of individual exon skipping events in MSBB.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q9Y2J2502688503689Alternative sequenceID=VSP_000483;Note=In isoform 2%2C isoform 3 and isoform 4. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:14702039,PMID:15489334,PMID:98921
Q9Y2J250268811087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J250268821087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2502688555555Natural variantID=VAR_048353;Note=A->T;Dbxref=dbSNP:rs9966357
Q9Y2J2502688575575Natural variantID=VAR_048354;Note=Y->C;Dbxref=dbSNP:rs8082898
Q9Y2J2502688394513RegionNote=Hydrophilic
Q9Y2J2502688514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2707718708719Alternative sequenceID=VSP_000484;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:15489334,PMID:9892180
Q9Y2J270771811087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J270771821087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2707718708708Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WV92
Q9Y2J2707718514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2783823784824Alternative sequenceID=VSP_000485;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:15489334,PMID:9892180
Q9Y2J278382311087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J278382321087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2783823514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2102410508351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J21024105011087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J21024105021087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2102410508611083RegionNote=C-terminal (CTD)

check button Lost protein functional features of individual exon skipping events in Mayo.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q9Y2J2502688503689Alternative sequenceID=VSP_000483;Note=In isoform 2%2C isoform 3 and isoform 4. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:14702039,PMID:15489334,PMID:98921
Q9Y2J250268811087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J250268821087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2502688555555Natural variantID=VAR_048353;Note=A->T;Dbxref=dbSNP:rs9966357
Q9Y2J2502688575575Natural variantID=VAR_048354;Note=Y->C;Dbxref=dbSNP:rs8082898
Q9Y2J2502688394513RegionNote=Hydrophilic
Q9Y2J2502688514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2707718708719Alternative sequenceID=VSP_000484;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:15489334,PMID:9892180
Q9Y2J270771811087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J270771821087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2707718708708Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WV92
Q9Y2J2707718514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J2783823784824Alternative sequenceID=VSP_000485;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9892180;Dbxref=PMID:15489334,PMID:9892180
Q9Y2J278382311087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J278382321087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2783823514860RegionNote=Spectrin--actin-binding;Ontology_term=ECO:0000255;evidence=ECO:0000255
Q9Y2J29479908351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J294799011087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J294799021087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2947990960960Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9WV92
Q9Y2J2947990962962Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:24275569;Dbxref=PMID:16964243,PMID:24275569
Q9Y2J29479908611083RegionNote=C-terminal (CTD)
Q9Y2J299110238351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J2991102311087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J2991102321087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J299110238611083RegionNote=C-terminal (CTD)
Q9Y2J2102410508351087Alternative sequenceID=VSP_000486;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9892180;Dbxref=PMID:9892180
Q9Y2J21024105011087ChainID=PRO_0000219399;Note=Band 4.1-like protein 3
Q9Y2J21024105021087ChainID=PRO_0000423194;Note=Band 4.1-like protein 3%2C N-terminally processed
Q9Y2J2102410508611083RegionNote=C-terminal (CTD)


Top

3'-UTR located exon skipping events that lost miRNA binding sites in EPB41L3

check button 3'-UTR exon skipping evnets lost miRNA binding.
Tissue typeENSTExon skip startExon skip endmicroRNABinding site by TargetScanBinding type by TargetScanBdinding site by miRandaScore of miRandaEnergy by miRanda

Top

SNVs in the skipped exons for EPB41L3

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Depth of Coverage in the skipped exon of the mutated samples.

check button - Sashimi plot in the skipped exon of the mutated samples.

check button - Non-synonymous mutations located in the skipped exons.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange

Top

AD stage-associated exon skippint events for EPB41L3

check button Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR).
AD stage infoCohortTissueSE idCoefficient P-valueChromosomeStrandE1 startE1 endSkipped startSkipped endE2 startE2 end

Top

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for EPB41L3

check button sQTL information located at the skipped exons.
Tissue typeExon skip IDSNP idLocationP-valueFDR

Top

Correlation with RNA binding proteins (RBPs) for EPB41L3

check button Correlated RBP and related information.
Tissue typeRBP nameExon skip IDCorrelation coeifficientP-value
CBNUP42exon_skip_2953394.252488e-012.304832e-08
CBSRSF2exon_skip_1986985.226972e-011.858615e-12
CBTIA1exon_skip_1986986.094659e-011.930977e-17
CBRBM3exon_skip_1986985.264919e-011.202550e-12
CBFUBP3exon_skip_1986984.831992e-011.272685e-10
CBHNRNPDexon_skip_1986985.405579e-012.281929e-13
CBRALYLexon_skip_1986985.381362e-013.054697e-13
CBPABPC1exon_skip_1986985.462934e-011.133028e-13
CBSRSF9exon_skip_1986985.035507e-011.542912e-11
CBSRSF2exon_skip_2505844.242466e-013.406036e-08
CBRBFOX2exon_skip_2505844.034882e-011.762296e-07
CBRBM25exon_skip_2505844.222589e-014.005951e-08
CBTIA1exon_skip_2505845.983186e-011.609371e-16
CBHNRNPKexon_skip_2505844.683139e-017.047693e-10
CBUNKexon_skip_2505845.169536e-014.883175e-12
CBSF1exon_skip_2505844.038596e-011.712887e-07
CBHNRNPA1exon_skip_2505845.641270e-011.737735e-14
CBFUBP3exon_skip_2505844.263705e-012.860617e-08
CBHNRNPA0exon_skip_2505844.412253e-018.157375e-09
CBHNRNPA1L2exon_skip_2505844.675994e-017.538897e-10
CBHNRNPDLexon_skip_2505844.635516e-011.101045e-09
CBRBM45exon_skip_2505844.351900e-011.368048e-08
CBHNRNPDexon_skip_2505844.546707e-012.484770e-09
CBNUP42exon_skip_2505846.276961e-011.802189e-18
CBRALYLexon_skip_2505845.018668e-012.484238e-11
CBCPEB1exon_skip_2505844.400263e-019.047160e-09
CBPABPC1exon_skip_2505844.242347e-013.409346e-08
CBSRSF9exon_skip_2505844.216891e-014.195862e-08
CBHNRNPH2exon_skip_2505844.312571e-011.905850e-08
CBCNOT4exon_skip_908674.685612e-011.144650e-09
CBTRA2Aexon_skip_908674.632555e-011.857950e-09
CBFUBP1exon_skip_908674.420701e-011.185950e-08
CBRBM45exon_skip_90867-4.509091e-015.557178e-09
CBHNRNPDLexon_skip_65657-4.035001e-011.336522e-07
CBSRSF11exon_skip_2330375.325541e-015.004287e-13
CBSRSF1exon_skip_2330374.040059e-011.284795e-07
CBSRSF9exon_skip_2330375.632830e-011.082777e-14
CBEIF4Bexon_skip_2330374.637017e-017.482236e-10
CBRBM25exon_skip_1363594.394476e-016.829445e-09
CBTIA1exon_skip_1363595.409554e-011.823441e-13
CBHNRNPKexon_skip_1363594.287725e-011.713178e-08
CBPPRC1exon_skip_1363594.159837e-014.948241e-08
CBPUF60exon_skip_1363594.006482e-011.667672e-07
CBTRA2Aexon_skip_240597-4.859771e-011.669504e-10
CBNUP42exon_skip_2405975.732973e-017.825081e-15
CBPABPC4exon_skip_2405974.682436e-019.143843e-10
DLPFCRBFOX2exon_skip_2505846.690680e-012.795056e-43
DLPFCELAVL4exon_skip_2505844.306044e-015.168942e-16
DLPFCRC3H1exon_skip_2505845.033250e-013.794998e-22
DLPFCKHDRBS2exon_skip_2505846.502808e-013.299446e-40
DLPFCPUM1exon_skip_2505844.589458e-013.126883e-18
DLPFCCPEB1exon_skip_2505845.625670e-012.358980e-28
DLPFCEIF4Bexon_skip_2505844.568395e-014.647119e-18
DLPFCELAVL4exon_skip_1986985.806337e-014.915461e-32
DLPFCRC3H1exon_skip_1986985.287455e-016.974502e-26
DLPFCRALYLexon_skip_1986984.621119e-012.170163e-19
DLPFCTARDBPexon_skip_464075.067058e-012.553226e-17
DLPFCSRSF2exon_skip_464075.894353e-013.202034e-24
DLPFCELAVL4exon_skip_464077.648962e-013.982602e-48
DLPFCELAVL1exon_skip_464075.142183e-017.174727e-18
DLPFCSFPQexon_skip_464075.387838e-019.012823e-20
DLPFCCNOT4exon_skip_464076.125314e-011.601957e-26
DLPFCTIA1exon_skip_464074.944556e-011.894249e-16
DLPFCRBM5exon_skip_464075.357658e-011.573304e-19
DLPFCMBNL1exon_skip_464075.750230e-017.084362e-23
DLPFCTRNAU1APexon_skip_464074.034801e-015.722954e-11
DLPFCPCBP1exon_skip_464077.004343e-012.604196e-37
DLPFCILF2exon_skip_464075.606801e-011.332106e-21
DLPFCHNRNPKexon_skip_464076.383015e-012.532844e-29
DLPFCTRA2Aexon_skip_464074.358750e-019.782897e-13
DLPFCPCBP2exon_skip_464076.647195e-011.743402e-32
DLPFCRC3H1exon_skip_464075.366373e-011.340284e-19
DLPFCSNRPAexon_skip_464075.805293e-012.209710e-23
DLPFCRBM24exon_skip_464076.164847e-016.189720e-27
DLPFCENOX1exon_skip_464077.181978e-015.480368e-40
DLPFCPPRC1exon_skip_464076.467652e-012.657697e-30
DLPFCHNRNPA2B1exon_skip_464075.506710e-019.503282e-21
DLPFCPUF60exon_skip_464075.827352e-011.377020e-23
DLPFCRALYLexon_skip_464076.918787e-014.321617e-36
DLPFCEIF4G2exon_skip_464076.508444e-018.739042e-31
DLPFCSNRNP70exon_skip_464074.405984e-015.208351e-13
DLPFCPTBP3exon_skip_464076.054608e-018.490730e-26
DLPFCHNRNPLexon_skip_464076.355938e-015.133655e-29
DLPFCRBM23exon_skip_464075.702558e-011.908638e-22
DLPFCEWSR1exon_skip_464075.800807e-012.431695e-23
DLPFCSRSF1exon_skip_464075.614916e-011.132625e-21
DLPFCSRSF9exon_skip_464075.878231e-014.562497e-24
DLPFCSRSF5exon_skip_464075.517396e-017.729108e-21
DLPFCHNRNPH2exon_skip_464076.646442e-011.781821e-32
DLPFCESRP1exon_skip_464075.228164e-011.614069e-18
DLPFCNOVA1exon_skip_464076.801895e-011.719030e-34
DLPFCEIF4Bexon_skip_2330374.158945e-011.075615e-15
FLSRSF2exon_skip_1986984.735581e-012.384345e-12
FLMSI1exon_skip_198698-4.361273e-011.664074e-10
FLELAVL4exon_skip_1986986.333568e-012.254632e-23
FLILF2exon_skip_1986985.035769e-015.344990e-14
FLRALYLexon_skip_1986985.254910e-012.616582e-15
FLNOVA1exon_skip_1986984.586401e-011.377752e-11
FLELAVL4exon_skip_2505844.844658e-019.573637e-12
HCCRBM4Bexon_skip_73613-4.042666e-014.065095e-12
HCCRBMS3exon_skip_198698-4.467563e-011.061278e-14
HCCMSI1exon_skip_198698-5.635036e-014.131241e-24
HCCSFPQexon_skip_198698-5.540839e-013.291551e-23
HCCSRSF11exon_skip_198698-4.951321e-013.621972e-18
HCCTIA1exon_skip_198698-5.318374e-013.438501e-21
HCCFUBP3exon_skip_198698-4.251490e-012.544048e-13
HCCFUBP1exon_skip_198698-4.474835e-019.498886e-15
HCCPABPC1exon_skip_198698-4.803520e-014.752217e-17
HCCRBM41exon_skip_198698-4.629053e-018.489857e-16
HCCHNRNPFexon_skip_198698-6.013265e-014.901638e-28
HCCRBM4exon_skip_198698-4.186219e-016.358480e-13
HCCSRSF11exon_skip_233037-4.291458e-011.296226e-13
HCCRBM4Bexon_skip_233037-4.593828e-011.320923e-15
HCCMSI1exon_skip_136359-4.413826e-011.916451e-14
HCCRBM25exon_skip_136359-4.225516e-013.005339e-13
HCCSFPQexon_skip_136359-4.070596e-012.553079e-12
HCCRBM6exon_skip_136359-5.072221e-012.969179e-19
HCCTIA1exon_skip_136359-4.271715e-011.554000e-13
HCCRBM5exon_skip_136359-4.493413e-015.683370e-15
HCCTRNAU1APexon_skip_136359-4.697531e-012.168397e-16
HCCPCBP4exon_skip_136359-6.249803e-015.507854e-31
HCCHNRNPA2B1exon_skip_136359-4.090816e-011.943054e-12
HCCPUF60exon_skip_136359-4.294291e-011.121705e-13
HCCPTBP1exon_skip_136359-5.399612e-014.625263e-22
HCCSNRNP70exon_skip_136359-4.266782e-011.668188e-13
HCCSRSF5exon_skip_136359-4.933582e-013.743582e-18
HCCHNRNPFexon_skip_136359-5.305675e-013.177037e-21
IFGNOVA1exon_skip_2684634.747557e-011.068691e-02
IFGENOX1exon_skip_736134.076068e-013.131787e-02
IFGESRP1exon_skip_736135.304531e-013.686851e-03
IFGNOVA1exon_skip_736134.130830e-012.890317e-02
IFGELAVL4exon_skip_1986986.145650e-015.023963e-04
IFGIGF2BP2exon_skip_198698-4.765056e-011.036209e-02
IFGRALYLexon_skip_1986986.123672e-015.330621e-04
IFGESRP1exon_skip_1986984.906961e-018.020376e-03
IFGRBFOX2exon_skip_2505846.204820e-014.273846e-04
IFGELAVL4exon_skip_2505845.588719e-011.992611e-03
IFGIGF2BP2exon_skip_250584-5.283633e-013.849550e-03
IFGRBM47exon_skip_250584-4.785529e-019.992584e-03
IFGQKIexon_skip_250584-4.841184e-019.043438e-03
IFGKHDRBS2exon_skip_2505844.937022e-017.586345e-03
IFGKHDRBS3exon_skip_2505845.495620e-012.452124e-03
IFGRBM24exon_skip_2505844.712487e-011.136357e-02
IFGHNRNPA0exon_skip_2505844.476426e-011.691110e-02
IFGRALYLexon_skip_2505845.046551e-016.168421e-03
IFGPTBP1exon_skip_250584-4.224292e-012.513151e-02
IFGESRP1exon_skip_2505844.142070e-012.842670e-02
IFGRBMS2exon_skip_656574.371310e-012.260755e-02
IFGPCBP4exon_skip_656574.174547e-013.026993e-02
IFGRBM24exon_skip_1363595.274764e-013.920427e-03
IFGRALYLexon_skip_1363595.412128e-012.938979e-03
IFGNOVA1exon_skip_1363594.524004e-011.564241e-02
PCCMSI1exon_skip_198698-4.454412e-011.114737e-11
PCCELAVL4exon_skip_1986986.451588e-013.170383e-26
PCCRALYLexon_skip_1986985.094483e-012.463931e-15
PCCPABPC1exon_skip_198698-5.167434e-018.404085e-16
PCCHNRNPFexon_skip_198698-6.043593e-012.130690e-22
PCCRBMS2exon_skip_250584-5.634440e-014.486977e-19
PCCRBMS1exon_skip_250584-4.162522e-013.001915e-10
PCCRBFOX2exon_skip_2505846.490128e-011.285762e-26
PCCELAVL4exon_skip_2505845.613524e-016.451992e-19
PCCZNF326exon_skip_250584-4.765339e-012.324339e-13
PCCRBM6exon_skip_250584-4.130730e-014.217631e-10
PCCIGF2BP2exon_skip_250584-4.037157e-011.124141e-09
PCCPCBP4exon_skip_250584-4.608252e-011.724818e-12
PCCQKIexon_skip_250584-5.100124e-012.269337e-15
PCCZFP36exon_skip_250584-4.129180e-014.287741e-10
PCCFUBP3exon_skip_250584-4.468923e-019.385333e-12
PCCPTBP1exon_skip_250584-5.921251e-012.354442e-21
PCCCPEB1exon_skip_2505845.263745e-011.951602e-16
PCCPABPC1exon_skip_250584-4.658836e-019.147154e-13
PCCHNRNPFexon_skip_250584-5.200874e-015.088591e-16
PCCSFPQexon_skip_136359-4.082677e-015.291904e-10
PCCRBM6exon_skip_136359-4.367086e-012.231688e-11
PCCIGF2BP2exon_skip_136359-4.399886e-011.519377e-11
PCCTRNAU1APexon_skip_136359-4.512877e-013.913930e-12
PCCPCBP4exon_skip_136359-4.474612e-016.230626e-12
PCCPTBP1exon_skip_136359-5.436698e-017.388895e-18
PCCHNRNPFexon_skip_136359-5.154931e-016.325793e-16
PGHNRNPH2exon_skip_736134.038615e-011.888145e-08
PGSRSF2exon_skip_1986984.953739e-015.688732e-13
PGMSI1exon_skip_198698-4.261652e-011.193382e-09
PGELAVL4exon_skip_1986988.370334e-012.477318e-50
PGSFPQexon_skip_1986984.253836e-011.288818e-09
PGSRSF11exon_skip_1986984.823492e-012.744045e-12
PGCNOT4exon_skip_1986984.530178e-017.510375e-11
PGRBM3exon_skip_1986984.701993e-011.122957e-11
PGILF2exon_skip_1986985.693722e-011.848209e-17
PGRC3H1exon_skip_1986984.400873e-012.931807e-10
PGHNRNPDexon_skip_1986985.276403e-018.546548e-15
PGRALYLexon_skip_1986987.813989e-019.697913e-40
PGSRSF1exon_skip_1986984.461489e-011.559373e-10
PGSRSF9exon_skip_1986984.548780e-016.144839e-11
PGSART3exon_skip_1986985.029762e-012.200756e-13
PGNOVA1exon_skip_1986986.432934e-013.151783e-23
PGRBM4exon_skip_1986984.682536e-011.400059e-11
PGRBFOX2exon_skip_2505845.385235e-015.857721e-13
PGELAVL4exon_skip_2505845.711645e-011.034766e-14
PGMATR3exon_skip_2505844.613511e-011.725771e-09
PGKHDRBS2exon_skip_2505844.490549e-015.177861e-09
PGZFP36exon_skip_250584-4.078678e-011.517608e-07
PGKHDRBS3exon_skip_2505844.868473e-011.531952e-10
PGRBM24exon_skip_2505844.607918e-011.815947e-09
PGPUM1exon_skip_2505844.073115e-011.583662e-07
PGRALYLexon_skip_2505845.384752e-015.890981e-13
PGCPEB1exon_skip_2505844.577497e-012.391689e-09
PGHNRNPH2exon_skip_2505844.536804e-013.442455e-09
PGNOVA1exon_skip_2505844.308651e-012.433413e-08
PGELAVL4exon_skip_1363596.280694e-011.104815e-22
PGPCBP1exon_skip_1363595.096463e-013.215301e-14
PGRBM24exon_skip_1363595.099142e-013.101794e-14
PGRALYLexon_skip_1363595.761842e-011.492952e-18
PGHNRNPH2exon_skip_1363595.087754e-013.612935e-14
STGHNRNPH2exon_skip_736134.342106e-012.954545e-05
STGELAVL4exon_skip_1986986.325395e-014.964004e-11
STGRALYLexon_skip_1986986.098115e-013.629062e-10
STGNOVA1exon_skip_1986985.485759e-013.782461e-08
STGELAVL4exon_skip_2505844.709260e-011.040834e-05
STGIGF2BP2exon_skip_250584-4.370578e-015.046135e-05
STGZFP36exon_skip_250584-5.115965e-011.235280e-06
STGRALYLexon_skip_2505844.307018e-016.663817e-05
STGPTBP1exon_skip_250584-5.186889e-018.275504e-07
STGMSI1exon_skip_136359-4.502913e-016.677878e-06
STGELAVL4exon_skip_1363595.274952e-016.565521e-08
STGRALYLexon_skip_1363594.808434e-011.225863e-06
STGPTBP1exon_skip_136359-4.390380e-011.197912e-05
STGHNRNPH2exon_skip_1363594.453503e-018.653206e-06
TCILF2exon_skip_736134.691970e-013.894814e-10
TCNUP42exon_skip_736136.500475e-011.394064e-20
TCHNRNPH2exon_skip_736136.504546e-011.295821e-20
TCESRP1exon_skip_736136.390777e-019.584479e-20
TCNOVA1exon_skip_736135.621768e-011.031923e-14
TCSRSF2exon_skip_1986985.111078e-014.991397e-12
TCELAVL4exon_skip_1986988.761173e-016.221781e-52
TCRBM3exon_skip_1986984.569092e-011.254410e-09
TCILF2exon_skip_1986985.189330e-012.067880e-12
TCHNRNPDexon_skip_1986986.451447e-013.332103e-20
TCRALYLexon_skip_1986988.785970e-011.394134e-52
TCESRP1exon_skip_1986986.800633e-014.645837e-23
TCNOVA1exon_skip_1986986.731781e-011.823842e-22
TCSRSF2exon_skip_2505845.392164e-011.891076e-13
TCRBFOX2exon_skip_2505847.876739e-014.655594e-35
TCELAVL4exon_skip_2505847.257416e-011.881276e-27
TCRBM25exon_skip_2505845.470790e-017.161306e-14
TCELAVL1exon_skip_2505844.125356e-015.937398e-08
TCRBM6exon_skip_250584-4.134348e-015.520635e-08
TCSRSF11exon_skip_2505844.250400e-012.116689e-08
TCCNOT4exon_skip_2505844.065394e-019.594071e-08
TCTIA1exon_skip_2505844.128673e-015.780251e-08
TCRBM3exon_skip_2505844.364214e-017.976774e-09
TCMBNL1exon_skip_2505844.404323e-015.606670e-09
TCMATR3exon_skip_2505847.013750e-015.264878e-25
TCILF2exon_skip_2505845.211835e-011.598238e-12
TCHNRNPKexon_skip_2505844.555673e-011.421348e-09
TCRC3H1exon_skip_2505844.161548e-014.423994e-08
TCKHDRBS2exon_skip_2505847.209499e-015.972080e-27
TCKHDRBS3exon_skip_2505846.352034e-011.858947e-19
TCRBM24exon_skip_2505846.441963e-013.936639e-20
TCENOX1exon_skip_2505844.334606e-011.031793e-08
TCHNRNPA0exon_skip_2505846.643833e-019.926467e-22
TCPUM1exon_skip_2505846.422323e-015.549705e-20
TCPPRC1exon_skip_2505844.243730e-012.238784e-08
TCHNRNPA1L2exon_skip_2505845.289875e-016.445020e-13
TCHNRNPDLexon_skip_2505845.080503e-017.000349e-12
TCRBM45exon_skip_2505845.217351e-011.499995e-12
TCHNRNPDexon_skip_2505846.468243e-012.476574e-20
TCNUP42exon_skip_2505846.949062e-012.137397e-24
TCRALYLexon_skip_2505847.066849e-011.620138e-25
TCEIF4G2exon_skip_2505844.582825e-011.103225e-09
TCPTBP3exon_skip_2505845.235500e-011.216458e-12
TCCPEB4exon_skip_2505844.701593e-013.546924e-10
TCCELF1exon_skip_2505846.157683e-014.497602e-18
TCCPEB1exon_skip_2505846.120944e-018.014809e-18
TCEWSR1exon_skip_2505844.768805e-011.830149e-10
TCSRSF5exon_skip_2505844.748664e-012.234883e-10
TCHNRNPH2exon_skip_2505846.908512e-015.048674e-24
TCESRP1exon_skip_2505846.316290e-013.397079e-19
TCSART3exon_skip_2505844.740666e-012.418557e-10
TCNOVA1exon_skip_2505846.609573e-011.891184e-21
TCELAVL4exon_skip_65657-6.176993e-015.384975e-18
TCNUP42exon_skip_65657-4.210494e-013.613759e-08
TCRALYLexon_skip_65657-6.373055e-012.201495e-19
TCSRSF9exon_skip_2330374.081538e-018.439057e-08
TCSRSF2exon_skip_1363594.199823e-013.228736e-08
TCELAVL4exon_skip_1363598.596510e-016.043386e-48
TCELAVL1exon_skip_1363594.119885e-016.205568e-08
TCRBM6exon_skip_136359-4.064152e-019.688980e-08
TCCNOT4exon_skip_1363594.908941e-014.394456e-11
TCMBNL1exon_skip_1363595.172058e-012.516720e-12
TCILF2exon_skip_1363595.118842e-014.578116e-12
TCHNRNPKexon_skip_1363594.083283e-018.322500e-08
TCRBM24exon_skip_1363598.299258e-016.828828e-42
TCENOX1exon_skip_1363594.300941e-011.378398e-08
TCRALYLexon_skip_1363598.670586e-011.131384e-49
TCEIF4G2exon_skip_1363594.893590e-015.154112e-11
TCPTBP3exon_skip_1363595.935016e-011.333947e-16
TCSRSF9exon_skip_1363594.268449e-011.817525e-08
TCHNRNPH2exon_skip_1363597.192277e-018.992620e-27
TCESRP1exon_skip_1363596.264279e-018.055193e-19
TCNOVA1exon_skip_1363594.910505e-014.323451e-11

Top

RelatedDrugs for EPB41L3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for EPB41L3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource