|
Open reading frame (ORF) annotation in the exon skipping event | |
3'-UTR located exon skipping events lost miRNA binding sites | |
Splicing Quantitative Trait Loci (sQTLs) in the skipped exons | |
Gene summary for MYCBP2 |
Gene summary |
Gene information | Gene symbol | MYCBP2 | Gene ID | 23077 |
Gene name | MYC binding protein 2 | |
Synonyms | Myc-bp2|PAM|PHR1|Phr | |
Cytomap | 13q22.3 | |
Type of gene | protein-coding | |
Description | E3 ubiquitin-protein ligase MYCBP2HighwireMYC binding protein 2, E3 ubiquitin protein ligasePAM/Highwire/RPM-1 protein 1RING-type E3 ubiquitin transferase MYCBP2myc-binding protein 2pam/highwire/rpm-1 proteinprotein associated with Myc | |
Modification date | 20200313 | |
UniProtAcc | ||
Context |
Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Gene | GO ID | GO term | PubMed ID |
MYCBP2 | GO:0016567 | protein ubiquitination | 29643511 |
MYCBP2 | GO:0031398 | positive regulation of protein ubiquitination | 20534529 |
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Gene structures and expression levels for MYCBP2 |
Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Differentially expressed gene analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
PCC | DOWN | ENST00000596342.1 | MYCBP2-AS1-205:lncRNA:MYCBP2 | 1.643412e+00 | -8.372332e-01 | 2.085939e-03 | 4.018951e-02 |
PG | DOWN | ENST00000485061.2 | MYCBP2-207:lncRNA:MYCBP2 | 3.530083e+01 | -9.255918e-01 | 6.584670e-04 | 1.076606e-02 |
CB | DOWN | ENST00000491491.1 | MYCBP2-209:lncRNA:MYCBP2 | 1.087555e+00 | -3.675733e+00 | 1.295125e-02 | 4.288488e-02 |
Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for MYCBP2 |
Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
All exon skipping events in AD cohorts. |
Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
exon_skip_107471 | chr13 | 77061169:77061301:77061662:77061790:77062596:77062697 | 77061662:77061790 |
exon_skip_124061 | chr13 | 77180127:77180318:77181701:77181922:77185103:77185371 | 77181701:77181922 |
exon_skip_130300 | chr13 | 77125336:77125468:77126318:77126542:77139196:77139336 | 77126318:77126542 |
exon_skip_137057 | chr13 | 77157937:77158109:77161906:77161955:77164454:77164541 | 77161906:77161955 |
exon_skip_14754 | chr13 | 77070631:77070711:77076760:77076849:77077148:77077387 | 77076760:77076849 |
exon_skip_167020 | chr13 | 77098885:77099013:77103209:77103310:77118340:77118462 | 77103209:77103310 |
exon_skip_17287 | chr13 | 77056986:77057093:77058218:77058406:77059523:77059626 | 77058218:77058406 |
exon_skip_176965 | chr13 | 77288161:77288376:77296599:77296674:77326474:77326540 | 77296599:77296674 |
exon_skip_191829 | chr13 | 77098885:77099013:77103209:77103310:77118340:77118396 | 77103209:77103310 |
exon_skip_211813 | chr13 | 77270031:77270063:77270296:77270538:77273472:77273511 | 77270296:77270538 |
exon_skip_21425 | chr13 | 77288161:77288376:77296599:77296674:77326474:77326679 | 77296599:77296674 |
exon_skip_219067 | chr13 | 77225435:77225554:77233156:77233263:77243059:77243160 | 77233156:77233263 |
exon_skip_242586 | chr13 | 77096312:77096481:77097370:77099013:77121373:77121495 | 77097370:77099013 |
exon_skip_243579 | chr13 | 77140047:77140163:77140846:77140943:77144445:77144560 | 77140846:77140943 |
exon_skip_243636 | chr13 | 77070631:77070711:77076751:77076849:77077148:77077387 | 77076751:77076849 |
exon_skip_251993 | chr13 | 77126452:77126542:77129156:77129230:77139196:77139336 | 77129156:77129230 |
exon_skip_264899 | chr13 | 77098885:77099013:77118340:77118519:77121373:77121392 | 77118340:77118519 |
exon_skip_272991 | chr13 | 77098885:77099013:77118340:77118519:77121373:77121495 | 77118340:77118519 |
exon_skip_30648 | chr13 | 77270296:77270538:77272323:77272399:77273472:77273511 | 77272323:77272399 |
exon_skip_31819 | chr13 | 77211956:77212160:77217840:77217957:77224451:77224532 | 77217840:77217957 |
exon_skip_32556 | chr13 | 77273472:77273668:77278758:77278911:77288161:77288376 | 77278758:77278911 |
exon_skip_48320 | chr13 | 77087484:77087633:77088832:77089031:77090106:77090263 | 77088832:77089031 |
exon_skip_66489 | chr13 | 77051811:77051918:77055558:77055767:77056986:77057093 | 77055558:77055767 |
exon_skip_7719 | chr13 | 77126318:77126542:77129156:77129230:77139196:77139336 | 77129156:77129230 |
exon_skip_79940 | chr13 | 77270398:77270538:77272323:77272399:77273472:77273511 | 77272323:77272399 |
exon_skip_9502 | chr13 | 77087535:77087633:77088832:77089031:77090106:77090263 | 77088832:77089031 |
Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
exon_skip_130300 | MSBB_PG | 5.017600e-01 | 3.751852e-01 | 1.265748e-01 | 2.007674e-06 |
exon_skip_251993 | MSBB_PG | 5.094400e-01 | 6.251923e-01 | -1.157523e-01 | 1.225577e-02 |
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Open reading frame (ORF) annotation in the exon skipping event for MYCBP2 |
Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000357337 | 77140846 | 77140943 | Frame-shift |
ENST00000544440 | 77140846 | 77140943 | Frame-shift |
ENST00000357337 | 77217840 | 77217957 | Frame-shift |
ENST00000544440 | 77217840 | 77217957 | Frame-shift |
ENST00000357337 | 77278758 | 77278911 | Frame-shift |
ENST00000544440 | 77278758 | 77278911 | Frame-shift |
ENST00000357337 | 77296599 | 77296674 | Frame-shift |
ENST00000357337 | 77058218 | 77058406 | In-frame |
ENST00000544440 | 77058218 | 77058406 | In-frame |
ENST00000357337 | 77076751 | 77076849 | In-frame |
ENST00000544440 | 77076751 | 77076849 | In-frame |
ENST00000357337 | 77097370 | 77099013 | In-frame |
ENST00000544440 | 77097370 | 77099013 | In-frame |
ENST00000357337 | 77126318 | 77126542 | In-frame |
ENST00000544440 | 77126318 | 77126542 | In-frame |
ENST00000357337 | 77181701 | 77181922 | In-frame |
ENST00000544440 | 77181701 | 77181922 | In-frame |
ENST00000357337 | 77233156 | 77233263 | In-frame |
ENST00000544440 | 77233156 | 77233263 | In-frame |
Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000357337 | 77140846 | 77140943 | Frame-shift |
ENST00000544440 | 77140846 | 77140943 | Frame-shift |
ENST00000357337 | 77217840 | 77217957 | Frame-shift |
ENST00000544440 | 77217840 | 77217957 | Frame-shift |
ENST00000357337 | 77278758 | 77278911 | Frame-shift |
ENST00000544440 | 77278758 | 77278911 | Frame-shift |
ENST00000357337 | 77296599 | 77296674 | Frame-shift |
ENST00000357337 | 77058218 | 77058406 | In-frame |
ENST00000544440 | 77058218 | 77058406 | In-frame |
ENST00000357337 | 77076751 | 77076849 | In-frame |
ENST00000544440 | 77076751 | 77076849 | In-frame |
ENST00000357337 | 77097370 | 77099013 | In-frame |
ENST00000544440 | 77097370 | 77099013 | In-frame |
ENST00000357337 | 77126318 | 77126542 | In-frame |
ENST00000544440 | 77126318 | 77126542 | In-frame |
ENST00000357337 | 77233156 | 77233263 | In-frame |
ENST00000544440 | 77233156 | 77233263 | In-frame |
ENST00000357337 | 77270296 | 77270538 | In-frame |
ENST00000544440 | 77270296 | 77270538 | In-frame |
Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
ENST | Start of skipped exon | End of skipped exon | ORF |
ENST00000357337 | 77088832 | 77089031 | Frame-shift |
ENST00000544440 | 77088832 | 77089031 | Frame-shift |
ENST00000357337 | 77140846 | 77140943 | Frame-shift |
ENST00000544440 | 77140846 | 77140943 | Frame-shift |
ENST00000357337 | 77161906 | 77161955 | Frame-shift |
ENST00000544440 | 77161906 | 77161955 | Frame-shift |
ENST00000357337 | 77217840 | 77217957 | Frame-shift |
ENST00000544440 | 77217840 | 77217957 | Frame-shift |
ENST00000357337 | 77278758 | 77278911 | Frame-shift |
ENST00000544440 | 77278758 | 77278911 | Frame-shift |
ENST00000357337 | 77296599 | 77296674 | Frame-shift |
ENST00000357337 | 77055558 | 77055767 | In-frame |
ENST00000544440 | 77055558 | 77055767 | In-frame |
ENST00000357337 | 77058218 | 77058406 | In-frame |
ENST00000544440 | 77058218 | 77058406 | In-frame |
ENST00000357337 | 77061662 | 77061790 | In-frame |
ENST00000544440 | 77061662 | 77061790 | In-frame |
ENST00000357337 | 77076751 | 77076849 | In-frame |
ENST00000544440 | 77076751 | 77076849 | In-frame |
ENST00000357337 | 77097370 | 77099013 | In-frame |
ENST00000544440 | 77097370 | 77099013 | In-frame |
ENST00000357337 | 77126318 | 77126542 | In-frame |
ENST00000544440 | 77126318 | 77126542 | In-frame |
ENST00000357337 | 77233156 | 77233263 | In-frame |
ENST00000544440 | 77233156 | 77233263 | In-frame |
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Infer the effects of exon skipping event on protein functional features for MYCBP2 |
p-ENSG00000005810_img4.png |
Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
Lost protein functional features of individual exon skipping events in ROSMAP. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Lost protein functional features of individual exon skipping events in MSBB. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Lost protein functional features of individual exon skipping events in Mayo. |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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3'-UTR located exon skipping events that lost miRNA binding sites in MYCBP2 |
3'-UTR exon skipping evnets lost miRNA binding. |
Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for MYCBP2 |
- Differential PSIs between mutated versus non-mutated samples. |
- Depth of Coverage in the skipped exon of the mutated samples. |
- Sashimi plot in the skipped exon of the mutated samples. |
- Non-synonymous mutations located in the skipped exons. |
Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
- Non-synonymous mutations located in the skipped exons in CCLE. |
Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for MYCBP2 |
Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
ADstage | MSBB | IFG | exon_skip_190924 | 3.844553e-01 | 4.338491e-02 | chr13 | - | 77098885 | 77099013 | 77118340 | 77118495 | 77121373 | 77121495 |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MYCBP2 |
sQTL information located at the skipped exons. |
Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for MYCBP2 |
Correlated RBP and related information. |
Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
CB | TARDBP | exon_skip_190924 | -4.522755e-01 | 1.264701e-08 |
CB | ZNF638 | exon_skip_190924 | -5.793801e-01 | 2.786244e-14 |
CB | RBM6 | exon_skip_190924 | -4.797216e-01 | 1.174890e-09 |
CB | CNOT4 | exon_skip_190924 | -4.585918e-01 | 7.455742e-09 |
CB | PCBP4 | exon_skip_190924 | 4.642012e-01 | 4.620969e-09 |
CB | PTBP1 | exon_skip_190924 | -4.464532e-01 | 2.039137e-08 |
CB | ZNF638 | exon_skip_272991 | -5.408499e-01 | 8.939136e-12 |
CB | RBM6 | exon_skip_130300 | 4.135461e-01 | 5.092629e-07 |
CB | HNRNPDL | exon_skip_130300 | -4.119093e-01 | 5.705284e-07 |
CB | NUP42 | exon_skip_130300 | -4.907939e-01 | 1.139187e-09 |
CB | PTBP1 | exon_skip_130300 | 5.165398e-01 | 1.038794e-10 |
CB | TIA1 | exon_skip_7719 | 5.486855e-01 | 4.664190e-12 |
CB | NUP42 | exon_skip_7719 | 6.613742e-01 | 1.886603e-18 |
CB | SRSF9 | exon_skip_7719 | 4.009500e-01 | 1.316736e-06 |
FL | HNRNPH2 | exon_skip_130300 | -4.275858e-01 | 6.181335e-10 |
FL | ILF2 | exon_skip_7719 | 4.206357e-01 | 2.048044e-09 |
FL | RALYL | exon_skip_7719 | 4.017275e-01 | 1.207941e-08 |
FL | PTBP1 | exon_skip_7719 | -4.114563e-01 | 4.914453e-09 |
FL | HNRNPH2 | exon_skip_7719 | 4.750112e-01 | 6.469489e-12 |
FL | ELAVL4 | exon_skip_219067 | -5.697987e-01 | 1.939212e-18 |
FL | KHDRBS3 | exon_skip_219067 | -5.107569e-01 | 1.498051e-14 |
FL | RALYL | exon_skip_219067 | -5.044734e-01 | 3.519316e-14 |
FL | NOVA1 | exon_skip_219067 | -4.053864e-01 | 3.132307e-09 |
HCC | MSI1 | exon_skip_130300 | 5.922505e-01 | 3.397351e-26 |
HCC | SFPQ | exon_skip_130300 | 4.853535e-01 | 6.867588e-17 |
HCC | RBM6 | exon_skip_130300 | 5.284972e-01 | 2.979741e-20 |
HCC | SRSF11 | exon_skip_130300 | 4.024646e-01 | 1.271554e-11 |
HCC | KHDRBS2 | exon_skip_130300 | -4.521452e-01 | 1.319306e-14 |
HCC | KHDRBS3 | exon_skip_130300 | 4.021113e-01 | 1.329993e-11 |
HCC | EIF4G2 | exon_skip_130300 | 4.814058e-01 | 1.322551e-16 |
HCC | PTBP1 | exon_skip_130300 | 6.141560e-01 | 1.477436e-28 |
HCC | SRSF4 | exon_skip_130300 | 4.554304e-01 | 8.041229e-15 |
HCC | HNRNPF | exon_skip_130300 | 5.340718e-01 | 1.008746e-20 |
HCC | ZNF326 | exon_skip_7719 | -5.364603e-01 | 7.483137e-21 |
HCC | U2AF2 | exon_skip_7719 | -4.216789e-01 | 1.125102e-12 |
HCC | TIA1 | exon_skip_7719 | -4.549383e-01 | 9.746457e-15 |
HCC | RBM5 | exon_skip_7719 | -5.746451e-01 | 2.458236e-24 |
HCC | KHDRBS3 | exon_skip_7719 | -4.113994e-01 | 4.407965e-12 |
HCC | FUBP1 | exon_skip_7719 | -4.399438e-01 | 8.841735e-14 |
HCC | RALY | exon_skip_7719 | -4.965654e-01 | 1.176173e-17 |
HCC | PTBP1 | exon_skip_7719 | -6.286395e-01 | 4.109974e-30 |
HCC | HNRNPF | exon_skip_7719 | -5.320945e-01 | 1.756798e-20 |
HCC | RBMS2 | exon_skip_219067 | 5.638780e-01 | 3.181391e-23 |
HCC | RBM6 | exon_skip_219067 | 4.638190e-01 | 2.834716e-15 |
HCC | SAMD4A | exon_skip_219067 | 4.899813e-01 | 4.162243e-17 |
HCC | RALYL | exon_skip_219067 | -4.389610e-01 | 1.134940e-13 |
IFG | RBM24 | exon_skip_190924 | 4.849678e-01 | 8.905454e-03 |
IFG | RBM6 | exon_skip_130300 | 4.085060e-01 | 3.091055e-02 |
IFG | IGF2BP2 | exon_skip_130300 | 4.492914e-01 | 1.646216e-02 |
IFG | FXR2 | exon_skip_130300 | -5.078900e-01 | 5.795303e-03 |
IFG | ILF2 | exon_skip_130300 | -5.415654e-01 | 2.916855e-03 |
IFG | KHDRBS3 | exon_skip_130300 | -6.186576e-01 | 4.493890e-04 |
IFG | PTBP1 | exon_skip_130300 | 5.844439e-01 | 1.091313e-03 |
IFG | HNRNPL | exon_skip_130300 | -4.186570e-01 | 2.660240e-02 |
IFG | HNRNPH2 | exon_skip_130300 | -6.049401e-01 | 6.491559e-04 |
IFG | ESRP1 | exon_skip_130300 | -4.276671e-01 | 2.319954e-02 |
IFG | TIA1 | exon_skip_7719 | -4.744018e-01 | 1.075363e-02 |
IFG | PTBP1 | exon_skip_7719 | -4.810566e-01 | 9.555764e-03 |
IFG | ESRP2 | exon_skip_7719 | -4.486605e-01 | 1.663277e-02 |
IFG | ELAVL4 | exon_skip_219067 | -6.674007e-01 | 1.046532e-04 |
IFG | FXR2 | exon_skip_219067 | -5.438670e-01 | 2.775938e-03 |
IFG | KHDRBS3 | exon_skip_219067 | -5.328083e-01 | 3.510565e-03 |
IFG | RALYL | exon_skip_219067 | -6.123402e-01 | 5.334486e-04 |
IFG | NOVA1 | exon_skip_219067 | -4.689132e-01 | 1.183375e-02 |
PCC | MSI1 | exon_skip_130300 | 5.029721e-01 | 1.216071e-13 |
PCC | PTBP1 | exon_skip_130300 | 5.209182e-01 | 1.117311e-14 |
PCC | ESRP2 | exon_skip_130300 | 4.056852e-01 | 5.808521e-09 |
PCC | HNRNPF | exon_skip_130300 | 4.159601e-01 | 2.172477e-09 |
PCC | RALYL | exon_skip_7719 | 5.197367e-01 | 1.313173e-14 |
PCC | PTBP1 | exon_skip_7719 | -5.667162e-01 | 1.278419e-17 |
PCC | RBMS2 | exon_skip_219067 | 5.975642e-01 | 2.334638e-20 |
PCC | ELAVL4 | exon_skip_219067 | -6.262793e-01 | 9.557545e-23 |
PCC | SAMD4A | exon_skip_219067 | 4.439915e-01 | 7.114970e-11 |
PCC | FXR2 | exon_skip_219067 | -4.033190e-01 | 4.594626e-09 |
PCC | RALYL | exon_skip_219067 | -6.458202e-01 | 1.614830e-24 |
PCC | CPEB1 | exon_skip_219067 | -5.160858e-01 | 9.808308e-15 |
PCC | NOVA1 | exon_skip_219067 | -4.463419e-01 | 5.495917e-11 |
PG | FXR2 | exon_skip_130300 | -4.415759e-01 | 6.113343e-10 |
PG | KHDRBS2 | exon_skip_130300 | -4.784211e-01 | 1.257952e-11 |
PG | KHDRBS3 | exon_skip_130300 | -5.019525e-01 | 8.171128e-13 |
PG | PTBP1 | exon_skip_130300 | 4.068645e-01 | 1.588034e-08 |
PG | HNRNPH2 | exon_skip_130300 | -4.840078e-01 | 6.697425e-12 |
PG | NOVA1 | exon_skip_130300 | -4.091975e-01 | 1.290422e-08 |
PG | ELAVL4 | exon_skip_219067 | -7.215844e-01 | 9.735201e-35 |
PG | FXR2 | exon_skip_219067 | -4.805087e-01 | 2.055749e-13 |
PG | PCBP1 | exon_skip_219067 | -4.508265e-01 | 8.300708e-12 |
PG | KHDRBS3 | exon_skip_219067 | -5.978435e-01 | 1.516824e-21 |
PG | RALYL | exon_skip_219067 | -6.199571e-01 | 1.780142e-23 |
PG | CPEB1 | exon_skip_219067 | -4.434127e-01 | 1.980030e-11 |
PG | NOVA1 | exon_skip_219067 | -4.399984e-01 | 2.934303e-11 |
STG | MSI1 | exon_skip_130300 | 4.548655e-01 | 1.223118e-05 |
STG | IGF2BP2 | exon_skip_130300 | 4.002798e-01 | 1.472006e-04 |
STG | PCBP1 | exon_skip_130300 | -4.267809e-01 | 4.639563e-05 |
STG | KHDRBS3 | exon_skip_130300 | -4.183414e-01 | 6.772146e-05 |
STG | HNRNPH2 | exon_skip_130300 | -4.508103e-01 | 1.493676e-05 |
STG | ESRP2 | exon_skip_130300 | 4.037335e-01 | 1.273245e-04 |
STG | NOVA1 | exon_skip_130300 | -4.458926e-01 | 1.896858e-05 |
STG | ILF2 | exon_skip_7719 | 4.534946e-01 | 1.476891e-05 |
STG | KHDRBS3 | exon_skip_7719 | 5.152258e-01 | 5.310011e-07 |
STG | HNRNPC | exon_skip_7719 | 4.463291e-01 | 2.087097e-05 |
STG | RALYL | exon_skip_7719 | 5.375666e-01 | 1.344515e-07 |
STG | HNRNPL | exon_skip_7719 | 4.195100e-01 | 7.122994e-05 |
STG | HNRNPH2 | exon_skip_7719 | 4.848403e-01 | 2.958867e-06 |
STG | EIF4B | exon_skip_7719 | 4.156367e-01 | 8.433641e-05 |
STG | ZCRB1 | exon_skip_7719 | 4.116864e-01 | 9.997916e-05 |
STG | ELAVL4 | exon_skip_219067 | -6.382298e-01 | 1.009940e-11 |
STG | KHDRBS3 | exon_skip_219067 | -4.758506e-01 | 1.869242e-06 |
STG | RALYL | exon_skip_219067 | -5.812879e-01 | 1.527411e-09 |
STG | NOVA1 | exon_skip_219067 | -4.830770e-01 | 1.235249e-06 |
TC | RALYL | exon_skip_190924 | 4.021651e-01 | 6.396469e-07 |
TC | RBM24 | exon_skip_272991 | 4.178775e-01 | 4.152453e-07 |
TC | MSI1 | exon_skip_130300 | 4.993230e-01 | 6.100935e-10 |
TC | IGF2BP2 | exon_skip_130300 | 4.044602e-01 | 1.041881e-06 |
TC | KHDRBS2 | exon_skip_130300 | -7.247360e-01 | 1.986920e-23 |
TC | KHDRBS3 | exon_skip_130300 | -6.049761e-01 | 6.174932e-15 |
TC | NUP42 | exon_skip_130300 | -5.441860e-01 | 7.519488e-12 |
TC | PTBP1 | exon_skip_130300 | 5.892996e-01 | 4.450398e-14 |
TC | CELF1 | exon_skip_130300 | -4.100874e-01 | 7.118299e-07 |
TC | HNRNPH2 | exon_skip_130300 | -5.643750e-01 | 8.333364e-13 |
TC | ESRP1 | exon_skip_130300 | -5.410604e-01 | 1.043436e-11 |
TC | HNRNPF | exon_skip_130300 | 4.522887e-01 | 3.243608e-08 |
TC | NOVA1 | exon_skip_130300 | -6.006220e-01 | 1.080370e-14 |
TC | RBM25 | exon_skip_7719 | 4.394120e-01 | 1.356208e-07 |
TC | MBNL1 | exon_skip_7719 | 4.214932e-01 | 4.827325e-07 |
TC | ILF2 | exon_skip_7719 | 5.017701e-01 | 8.841003e-10 |
TC | KHDRBS3 | exon_skip_7719 | 6.265475e-01 | 9.329703e-16 |
TC | RBM24 | exon_skip_7719 | 6.102042e-01 | 8.034350e-15 |
TC | HNRNPA0 | exon_skip_7719 | 6.538445e-01 | 1.901704e-17 |
TC | NUP42 | exon_skip_7719 | 6.458944e-01 | 6.155317e-17 |
TC | RALYL | exon_skip_7719 | 6.765637e-01 | 5.414773e-19 |
TC | PTBP1 | exon_skip_7719 | -4.878771e-01 | 2.965092e-09 |
TC | CPEB4 | exon_skip_7719 | 4.212925e-01 | 4.894467e-07 |
TC | HNRNPH2 | exon_skip_7719 | 6.934771e-01 | 3.092894e-20 |
TC | ESRP1 | exon_skip_7719 | 5.686803e-01 | 1.133248e-12 |
TC | RBMS2 | exon_skip_219067 | 5.540374e-01 | 7.079190e-13 |
TC | ELAVL4 | exon_skip_219067 | -6.739157e-01 | 2.866495e-20 |
TC | FXR2 | exon_skip_219067 | -4.660129e-01 | 4.481859e-09 |
TC | KHDRBS3 | exon_skip_219067 | -5.989594e-01 | 2.749209e-15 |
TC | RALYL | exon_skip_219067 | -6.906780e-01 | 1.368572e-21 |
TC | CPEB1 | exon_skip_219067 | -4.092964e-01 | 3.861599e-07 |
TC | NOVA1 | exon_skip_219067 | -5.749637e-01 | 5.923527e-14 |
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RelatedDrugs for MYCBP2 |
Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MYCBP2 |
Diseases associated with this gene. (DisGeNet 4.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |