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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for RAB21 |
 Gene summary |
| Gene information | Gene symbol | RAB21 | Gene ID | 23011 |
| Gene name | RAB21, member RAS oncogene family | |
| Synonyms | - | |
| Cytomap | 12q21.1 | |
| Type of gene | protein-coding | |
| Description | ras-related protein Rab-21GTP-binding protein RAB21 | |
| Modification date | 20200313 | |
| UniProtAcc | A0A024RBA9, Q9UL25, | |
| Context | - 28547526(Rab21, a Novel PS1 Interactor, Regulates gamma-Secretase Activity via PS1 Subcellular Distribution) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| RAB21 | GO:0008089 | anterograde axonal transport | 22705394 |
| RAB21 | GO:0017157 | regulation of exocytosis | 22705394 |
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Gene structures and expression levels for RAB21 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000080371
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for RAB21 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_183789 | chr12 | 71773959:71774022:71782031:71782085:71782570:71782658 | 71782031:71782085 |
| exon_skip_184914 | chr12 | 71770610:71770699:71773959:71774022:71782031:71782085 | 71773959:71774022 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |