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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for R3HDM2 |
 Gene summary |
| Gene information | Gene symbol | R3HDM2 | Gene ID | 22864 |
| Gene name | R3H domain containing 2 | |
| Synonyms | CAG6|PR01365 | |
| Cytomap | 12q13.3 | |
| Type of gene | protein-coding | |
| Description | R3H domain-containing protein 2 | |
| Modification date | 20200320 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for R3HDM2 |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000179912
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
 |
| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| CB | UP | ENST00000429355.6 | R3HDM2-206:protein_coding:R3HDM2 | 4.824586e+01 | 1.395274e+00 | 9.405126e-08 | 2.015282e-06 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for R3HDM2 |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_103990 | chr12 | 57303176:57303217:57310264:57310463:57395749:57395818 | 57310264:57310463 |
| exon_skip_107623 | chr12 | 57283824:57284056:57288857:57288910:57289009:57289040 | 57288857:57288910 |
| exon_skip_119994 | chr12 | 57310453:57310463:57395749:57395818:57430720:57430790 | 57395749:57395818 |
| exon_skip_121005 | chr12 | 57269752:57269994:57272453:57272554:57280358:57280530 | 57272453:57272554 |
| exon_skip_150466 | chr12 | 57310340:57310463:57395749:57395818:57430720:57430790 | 57395749:57395818 |
| exon_skip_18768 | chr12 | 57297328:57297387:57298090:57298168:57299352:57299436 | 57298090:57298168 |
| exon_skip_195579 | chr12 | 57283824:57284056:57292572:57292667:57295399:57295507 | 57292572:57292667 |
| exon_skip_227710 | chr12 | 57300095:57300181:57303176:57303217:57310264:57310451 | 57303176:57303217 |
| exon_skip_236852 | chr12 | 57283824:57284056:57289009:57289040:57295399:57295507 | 57289009:57289040 |
| exon_skip_258320 | chr12 | 57289009:57289040:57292572:57292667:57295399:57295507 | 57292572:57292667 |
| exon_skip_65939 | chr12 | 57303176:57303217:57305640:57305663:57310264:57310451 | 57305640:57305663 |
| exon_skip_85918 | chr12 | 57303176:57303217:57305640:57305663:57310264:57310332 | 57305640:57305663 |
| exon_skip_94610 | chr12 | 57283824:57284056:57289009:57289040:57292572:57292667 | 57289009:57289040 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_107623 | MSBB_STG | 4.812121e-01 | 5.813043e-01 | -1.000922e-01 | 3.499761e-02 |
| exon_skip_107623 | MSBB_PG | 4.411719e-01 | 5.989091e-01 | -1.577372e-01 | 1.272144e-03 |
| exon_skip_150474 | Mayo_TC | 2.111250e-01 | 3.733803e-01 | -1.622553e-01 | 6.893968e-07 |
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Open reading frame (ORF) annotation in the exon skipping event for R3HDM2 |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000347140 | 57310264 | 57310463 | 3UTR-3CDS |
| ENST00000347140 | 57395749 | 57395818 | 3UTR-3UTR |
| ENST00000347140 | 57288857 | 57288910 | In-frame |
| ENST00000358907 | 57288857 | 57288910 | In-frame |
| ENST00000347140 | 57303176 | 57303217 | In-frame |
| ENST00000358907 | 57303176 | 57303217 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000347140 | 57310264 | 57310463 | 3UTR-3CDS |
| ENST00000347140 | 57395749 | 57395818 | 3UTR-3UTR |
| ENST00000347140 | 57288857 | 57288910 | In-frame |
| ENST00000358907 | 57288857 | 57288910 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000347140 | 57310264 | 57310463 | 3UTR-3CDS |
| ENST00000347140 | 57395749 | 57395818 | 3UTR-3UTR |
| ENST00000347140 | 57298090 | 57298168 | Frame-shift |
| ENST00000358907 | 57298090 | 57298168 | Frame-shift |
| ENST00000347140 | 57288857 | 57288910 | In-frame |
| ENST00000358907 | 57288857 | 57288910 | In-frame |
| ENST00000347140 | 57303176 | 57303217 | In-frame |
| ENST00000358907 | 57303176 | 57303217 | In-frame |
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Infer the effects of exon skipping event on protein functional features for R3HDM2 |
p-ENSG00000179912_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000347140 | 4348 | 976 | 57303176 | 57303217 | 557 | 597 | 55 | 68 |
| ENST00000358907 | 3991 | 976 | 57303176 | 57303217 | 201 | 241 | 55 | 68 |
| ENST00000347140 | 4348 | 976 | 57288857 | 57288910 | 1234 | 1286 | 281 | 298 |
| ENST00000358907 | 3991 | 976 | 57288857 | 57288910 | 878 | 930 | 281 | 298 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000347140 | 4348 | 976 | 57288857 | 57288910 | 1234 | 1286 | 281 | 298 |
| ENST00000358907 | 3991 | 976 | 57288857 | 57288910 | 878 | 930 | 281 | 298 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000347140 | 4348 | 976 | 57303176 | 57303217 | 557 | 597 | 55 | 68 |
| ENST00000358907 | 3991 | 976 | 57303176 | 57303217 | 201 | 241 | 55 | 68 |
| ENST00000347140 | 4348 | 976 | 57288857 | 57288910 | 1234 | 1286 | 281 | 298 |
| ENST00000358907 | 3991 | 976 | 57288857 | 57288910 | 878 | 930 | 281 | 298 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9Y2K5 | 55 | 68 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 55 | 68 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 296 | 298 | Alternative sequence | ID=VSP_026088;Note=In isoform 2. QIF->MIT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 296 | 298 | Alternative sequence | ID=VSP_026088;Note=In isoform 2. QIF->MIT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 288 | 369 | Compositional bias | Note=Ser-rich |
| Q9Y2K5 | 281 | 298 | 288 | 369 | Compositional bias | Note=Ser-rich |
| Q9Y2K5 | 281 | 298 | 233 | 310 | Domain | Note=SUZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01009 |
| Q9Y2K5 | 281 | 298 | 233 | 310 | Domain | Note=SUZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01009 |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9Y2K5 | 281 | 298 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 296 | 298 | Alternative sequence | ID=VSP_026088;Note=In isoform 2. QIF->MIT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 296 | 298 | Alternative sequence | ID=VSP_026088;Note=In isoform 2. QIF->MIT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 288 | 369 | Compositional bias | Note=Ser-rich |
| Q9Y2K5 | 281 | 298 | 288 | 369 | Compositional bias | Note=Ser-rich |
| Q9Y2K5 | 281 | 298 | 233 | 310 | Domain | Note=SUZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01009 |
| Q9Y2K5 | 281 | 298 | 233 | 310 | Domain | Note=SUZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01009 |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q9Y2K5 | 55 | 68 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 55 | 68 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 55 | 68 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 339 | Alternative sequence | ID=VSP_057391;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 295 | Alternative sequence | ID=VSP_026087;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 296 | 298 | Alternative sequence | ID=VSP_026088;Note=In isoform 2. QIF->MIT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 296 | 298 | Alternative sequence | ID=VSP_026088;Note=In isoform 2. QIF->MIT;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q9Y2K5 | 281 | 298 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 1 | 976 | Chain | ID=PRO_0000050787;Note=R3H domain-containing protein 2 |
| Q9Y2K5 | 281 | 298 | 288 | 369 | Compositional bias | Note=Ser-rich |
| Q9Y2K5 | 281 | 298 | 288 | 369 | Compositional bias | Note=Ser-rich |
| Q9Y2K5 | 281 | 298 | 233 | 310 | Domain | Note=SUZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01009 |
| Q9Y2K5 | 281 | 298 | 233 | 310 | Domain | Note=SUZ;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01009 |
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3'-UTR located exon skipping events that lost miRNA binding sites in R3HDM2 |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for R3HDM2 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for R3HDM2 |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for R3HDM2 |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
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Correlation with RNA binding proteins (RBPs) for R3HDM2 |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | TRA2A | exon_skip_107623 | -5.920411e-01 | 2.055055e-16 |
| CB | HNRNPA2B1 | exon_skip_107623 | -4.578159e-01 | 1.300262e-09 |
| CB | NUP42 | exon_skip_107623 | 5.326933e-01 | 4.922356e-13 |
| CB | CNOT4 | exon_skip_65939 | -4.686490e-01 | 4.663820e-10 |
| DLPFC | G3BP2 | exon_skip_258320 | -4.396036e-01 | 3.245375e-17 |
| DLPFC | PTBP3 | exon_skip_107623 | 4.143240e-01 | 1.878366e-15 |
| DLPFC | CPEB1 | exon_skip_107623 | 6.091739e-01 | 1.032976e-35 |
| DLPFC | ELAVL4 | exon_skip_121005 | 5.140300e-01 | 8.720501e-24 |
| FL | RBM24 | exon_skip_107623 | 4.508590e-01 | 5.294884e-11 |
| FL | HNRNPH2 | exon_skip_107623 | 4.386246e-01 | 1.972192e-10 |
| FL | RALYL | exon_skip_258320 | -4.075234e-01 | 3.362303e-09 |
| FL | SRSF9 | exon_skip_258320 | -4.372952e-01 | 1.637296e-10 |
| FL | NOVA1 | exon_skip_258320 | -4.042056e-01 | 4.625074e-09 |
| HCC | RBM6 | exon_skip_121005 | -5.654172e-01 | 1.822089e-24 |
| HCC | SRSF4 | exon_skip_121005 | -4.977448e-01 | 1.699924e-18 |
| HCC | RBM25 | exon_skip_107623 | -4.239022e-01 | 2.480890e-13 |
| HCC | TIA1 | exon_skip_107623 | -5.214585e-01 | 1.945464e-20 |
| HCC | RBM5 | exon_skip_107623 | -6.188825e-01 | 2.972164e-30 |
| HCC | TRNAU1AP | exon_skip_107623 | -4.783090e-01 | 5.162173e-17 |
| HCC | TRA2A | exon_skip_107623 | -4.769213e-01 | 6.533036e-17 |
| HCC | HNRNPA2B1 | exon_skip_107623 | -5.892930e-01 | 6.434621e-27 |
| HCC | PTBP1 | exon_skip_107623 | -7.156608e-01 | 3.883051e-44 |
| HCC | SRSF1 | exon_skip_107623 | -4.536137e-01 | 2.920738e-15 |
| HCC | HNRNPF | exon_skip_107623 | -6.298247e-01 | 1.405236e-31 |
| HCC | ZNF326 | exon_skip_65939 | 4.420790e-01 | 1.725250e-14 |
| HCC | PTBP1 | exon_skip_65939 | 4.258685e-01 | 1.873623e-13 |
| IFG | ELAVL4 | exon_skip_121005 | 5.003429e-01 | 6.697249e-03 |
| IFG | TIA1 | exon_skip_107623 | -4.914443e-01 | 7.910448e-03 |
| IFG | RBM5 | exon_skip_107623 | -4.870637e-01 | 8.572560e-03 |
| IFG | TRA2A | exon_skip_107623 | -4.449008e-01 | 1.768000e-02 |
| IFG | HNRNPA2B1 | exon_skip_107623 | -4.342232e-01 | 2.095404e-02 |
| IFG | PTBP1 | exon_skip_107623 | -5.501095e-01 | 2.422776e-03 |
| IFG | IGF2BP2 | exon_skip_236852 | -4.443796e-01 | 1.782936e-02 |
| IFG | HNRNPDL | exon_skip_258320 | 4.409399e-01 | 1.884144e-02 |
| IFG | RALYL | exon_skip_65939 | -5.000768e-01 | 6.731104e-03 |
| PCC | ELAVL4 | exon_skip_121005 | 5.198559e-01 | 6.182737e-16 |
| PCC | TRNAU1AP | exon_skip_107623 | -4.104620e-01 | 5.059905e-10 |
| PCC | TRA2A | exon_skip_107623 | -4.486297e-01 | 6.803353e-12 |
| PCC | HNRNPA2B1 | exon_skip_107623 | -4.051642e-01 | 8.827700e-10 |
| PCC | PTBP1 | exon_skip_107623 | -7.102589e-01 | 7.403989e-34 |
| PCC | CPEB1 | exon_skip_107623 | 4.670279e-01 | 6.980862e-13 |
| PCC | HNRNPF | exon_skip_107623 | -6.292438e-01 | 8.938168e-25 |
| PCC | ZNF326 | exon_skip_258320 | 4.860318e-01 | 5.734772e-14 |
| PCC | SFPQ | exon_skip_258320 | 4.029389e-01 | 1.112037e-09 |
| PCC | TRA2A | exon_skip_258320 | 4.046377e-01 | 9.324779e-10 |
| PCC | HNRNPF | exon_skip_258320 | 4.870260e-01 | 5.010303e-14 |
| PCC | ZNF326 | exon_skip_65939 | 4.994177e-01 | 8.967915e-15 |
| PCC | PTBP1 | exon_skip_65939 | 5.465933e-01 | 6.511619e-18 |
| PG | RBM25 | exon_skip_107623 | 5.904208e-01 | 1.413936e-18 |
| PG | TIA1 | exon_skip_107623 | 5.025148e-01 | 4.219787e-13 |
| PG | RBM5 | exon_skip_107623 | 4.233811e-01 | 2.352414e-09 |
| PG | TRNAU1AP | exon_skip_107623 | 4.357830e-01 | 7.015333e-10 |
| PG | ILF2 | exon_skip_107623 | 5.596762e-01 | 1.780338e-16 |
| PG | RBM24 | exon_skip_107623 | 6.560269e-01 | 6.816362e-24 |
| PG | NUP42 | exon_skip_107623 | 5.586526e-01 | 2.073640e-16 |
| PG | RALYL | exon_skip_107623 | 6.697050e-01 | 3.574951e-25 |
| PG | CPEB1 | exon_skip_107623 | 5.485020e-01 | 9.148295e-16 |
| PG | SRSF1 | exon_skip_107623 | 5.151920e-01 | 8.522797e-14 |
| PG | SRSF9 | exon_skip_107623 | 5.204436e-01 | 4.307846e-14 |
| PG | HNRNPH2 | exon_skip_107623 | 5.998886e-01 | 2.869479e-19 |
| STG | RBM24 | exon_skip_107623 | 4.623973e-01 | 5.068943e-06 |
| STG | RALYL | exon_skip_107623 | 4.768929e-01 | 2.304768e-06 |
| STG | HNRNPH2 | exon_skip_107623 | 4.929023e-01 | 9.245716e-07 |
| TC | SRSF2 | exon_skip_121005 | 4.568712e-01 | 1.258861e-09 |
| TC | ELAVL4 | exon_skip_121005 | 8.470385e-01 | 3.210325e-45 |
| TC | SRSF5 | exon_skip_121005 | 4.176021e-01 | 3.929112e-08 |
| TC | RBM25 | exon_skip_107623 | 4.864816e-01 | 6.934728e-11 |
| TC | ILF2 | exon_skip_107623 | 5.508278e-01 | 4.467040e-14 |
| TC | RBM24 | exon_skip_107623 | 7.972510e-01 | 1.830665e-36 |
| TC | NUP42 | exon_skip_107623 | 6.868049e-01 | 1.173836e-23 |
| TC | RALYL | exon_skip_107623 | 8.679596e-01 | 6.861448e-50 |
| TC | PTBP1 | exon_skip_107623 | -4.233632e-01 | 2.436608e-08 |
| TC | PTBP3 | exon_skip_107623 | 5.536315e-01 | 3.126413e-14 |
| TC | CPEB1 | exon_skip_107623 | 5.719766e-01 | 2.781662e-15 |
| TC | SRSF9 | exon_skip_107623 | 4.038897e-01 | 1.182515e-07 |
| TC | HNRNPH2 | exon_skip_107623 | 7.642871e-01 | 6.516386e-32 |
| TC | ESRP1 | exon_skip_107623 | 6.638725e-01 | 1.093361e-21 |
| TC | HNRNPH2 | exon_skip_236852 | 4.379347e-01 | 7.795344e-09 |
| TC | NOVA1 | exon_skip_236852 | 4.224421e-01 | 2.912143e-08 |
| TC | SRSF2 | exon_skip_258320 | -4.550220e-01 | 1.495148e-09 |
| TC | ILF2 | exon_skip_258320 | -4.847982e-01 | 8.238936e-11 |
| TC | G3BP2 | exon_skip_258320 | -6.863525e-01 | 1.288862e-23 |
| TC | HNRNPDL | exon_skip_258320 | -4.385608e-01 | 6.613040e-09 |
| TC | RALYL | exon_skip_258320 | -7.938335e-01 | 5.924244e-36 |
| TC | HNRNPH2 | exon_skip_258320 | -6.738554e-01 | 1.596875e-22 |
| TC | ESRP1 | exon_skip_258320 | -5.523936e-01 | 3.661416e-14 |
| TC | NOVA1 | exon_skip_258320 | -5.066142e-01 | 8.196277e-12 |
| TC | G3BP2 | exon_skip_65939 | -5.293501e-01 | 6.175216e-13 |
| TC | RALYL | exon_skip_65939 | -5.672140e-01 | 5.288684e-15 |
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RelatedDrugs for R3HDM2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for R3HDM2 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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