![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | Open reading frame (ORF) annotation in the exon skipping event |
![]() | |
![]() | 3'-UTR located exon skipping events lost miRNA binding sites |
![]() | |
![]() | |
![]() | Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
![]() | |
![]() | |
![]() |
Gene summary for ZNRF2 |
![]() |
Gene information | Gene symbol | ZNRF2 | Gene ID | 223082 |
Gene name | zinc and ring finger 2 | |
Synonyms | RNF202 | |
Cytomap | 7p14.3 | |
Type of gene | protein-coding | |
Description | E3 ubiquitin-protein ligase ZNRF2RING finger protein 202RING-type E3 ubiquitin transferase ZNRF2protein Ells2zinc and ring finger 2, E3 ubiquitin protein ligasezinc finger/RING finger 2zinc/RING finger protein 2 | |
Modification date | 20200313 | |
UniProtAcc | A0A090N8Y8, Q8NHG8, | |
Context |
![]() |
Gene | GO ID | GO term | PubMed ID |
Top |
Gene structures and expression levels for ZNRF2 |
![]() * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
![]() |
![]() |
Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
![]() |
Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
![]() |
Top |
Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for ZNRF2 |
![]() |
![]() |
Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
![]() |
Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
exon_skip_215715 | MSBB_PG | 2.859524e-01 | 3.964151e-01 | -1.104627e-01 | 6.130757e-03 |
Top |
Open reading frame (ORF) annotation in the exon skipping event for ZNRF2 |
![]() |
ENST | Start of skipped exon | End of skipped exon | ORF |
![]() |
ENST | Start of skipped exon | End of skipped exon | ORF |
![]() |
ENST | Start of skipped exon | End of skipped exon | ORF |
Top |
Infer the effects of exon skipping event on protein functional features for ZNRF2 |
p-ENSG00000180233_img4.png![]() |
![]() |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
![]() |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
![]() |
ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
![]() |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
![]() |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
![]() |
UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Top |
3'-UTR located exon skipping events that lost miRNA binding sites in ZNRF2 |
![]() |
Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
Top |
SNVs in the skipped exons for ZNRF2 |
![]() |
![]() |
![]() |
![]() |
Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
![]() |
Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
Top |
AD stage-associated exon skippint events for ZNRF2 |
![]() |
AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNRF2 |
![]() |
Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
Top |
Correlation with RNA binding proteins (RBPs) for ZNRF2 |
![]() |
Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
Top |
RelatedDrugs for ZNRF2 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNRF2 |
![]() (DisGeNet 4.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |