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| Open reading frame (ORF) annotation in the exon skipping event |
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| 3'-UTR located exon skipping events lost miRNA binding sites |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
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Gene summary for DTNB |
 Gene summary |
| Gene information | Gene symbol | DTNB | Gene ID | 1838 |
| Gene name | dystrobrevin beta | |
| Synonyms | - | |
| Cytomap | 2p23.3 | |
| Type of gene | protein-coding | |
| Description | dystrobrevin betaDTN-Bbeta-dystrobrevin | |
| Modification date | 20200327 | |
| UniProtAcc | ||
| Context | - 11222629(Oxidative Regulation of Large Conductance Calcium-Activated Potassium Channels) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Gene structures and expression levels for DTNB |
| Skipped exons in the ROSMAP, MSBB, and Mayo based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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ENSG00000138101
| Differentially expressed gene analysis across multiple brain tissues between AD and control. |
| Tissue type | DEG direction | Base mean exp. | log2FC(AD/control) | P-value | Adj. p-value |
| Differentially expressed isoform analysis across multiple brain tissues between AD and control. |
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| Tissue type | DEG direction | ENST | Transcript info. | Base mean exp. | log2FC(AD/control) | P-value | Adjc. p-value |
| PG | UP | ENST00000472690.5 | DTNB-213:lncRNA:DTNB | 8.558506e+00 | 8.836796e-01 | 2.446501e-03 | 2.755892e-02 |
| CB | DOWN | ENST00000497476.5 | DTNB-229:lncRNA:DTNB | 2.492017e+01 | -2.211890e+00 | 8.422148e-07 | 1.295194e-05 |
| CB | DOWN | ENST00000356599.9 | DTNB-204:nonsense_mediated_decay:DTNB | 9.213445e+01 | -8.998379e-01 | 6.535782e-05 | 5.160597e-04 |
| CB | DOWN | ENST00000406818.7 | DTNB-208:protein_coding:DTNB | 9.756820e+00 | -2.969282e+00 | 2.301574e-03 | 1.035627e-02 |
| TC | DOWN | ENST00000486555.5 | DTNB-220:lncRNA:DTNB | 8.657838e+00 | -1.150863e+00 | 4.208625e-05 | 8.107011e-04 |
| TC | DOWN | ENST00000473113.1 | DTNB-214:lncRNA:DTNB | 1.229359e+00 | -1.103211e+00 | 3.474454e-04 | 4.316972e-03 |
| TC | DOWN | ENST00000497476.5 | DTNB-229:lncRNA:DTNB | 8.085487e+01 | -1.009154e+00 | 4.770384e-04 | 5.544997e-03 |
| TC | DOWN | ENST00000489756.1 | DTNB-223:lncRNA:DTNB | 6.797454e+00 | -1.148846e+00 | 5.803802e-04 | 6.473790e-03 |
| TC | DOWN | ENST00000406818.7 | DTNB-208:protein_coding:DTNB | 2.891567e+01 | -1.849467e+00 | 5.434889e-03 | 3.567652e-02 |
| Landscape of isoform expressions across multiple brain tissues between AD and control. |
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Exon skipping events with PSIs in ROSMAP, MSBB, and Mayo for DTNB |
| Landscape of individual exon skipping event across AD tissues and controls (PSI heatmap). |
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| All exon skipping events in AD cohorts. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon |
| exon_skip_116435 | chr2 | 25580721:25580826:25607236:25607321:25628171:25628384 | 25607236:25607321 |
| exon_skip_157284 | chr2 | 25455405:25455494:25482796:25482873:25531473:25531597 | 25482796:25482873 |
| exon_skip_158899 | chr2 | 25388318:25388361:25419515:25419535:25427535:25427580 | 25419515:25419535 |
| exon_skip_166248 | chr2 | 25639014:25639094:25652594:25652661:25673386:25673429 | 25652594:25652661 |
| exon_skip_170073 | chr2 | 25379290:25379323:25387289:25387378:25388202:25388361 | 25387289:25387378 |
| exon_skip_172237 | chr2 | 25628183:25628384:25639014:25639094:25652594:25652661 | 25639014:25639094 |
| exon_skip_172307 | chr2 | 25433910:25433995:25451548:25451635:25482796:25482873 | 25451548:25451635 |
| exon_skip_174434 | chr2 | 25379290:25379323:25383836:25383889:25388202:25388361 | 25383836:25383889 |
| exon_skip_17897 | chr2 | 25419515:25419535:25427535:25427631:25432886:25432999 | 25427535:25427631 |
| exon_skip_199072 | chr2 | 25607287:25607321:25628171:25628384:25639014:25639094 | 25628171:25628384 |
| exon_skip_227533 | chr2 | 25580721:25580826:25596086:25596240:25628171:25628384 | 25596086:25596240 |
| exon_skip_233070 | chr2 | 25427535:25427631:25432886:25432999:25433910:25433995 | 25432886:25432999 |
| exon_skip_239173 | chr2 | 25388318:25388361:25419515:25419535:25427535:25427631 | 25419515:25419535 |
| exon_skip_23988 | chr2 | 25596124:25596240:25607236:25607321:25628171:25628384 | 25607236:25607321 |
| exon_skip_256634 | chr2 | 25383836:25383889:25388202:25388361:25427535:25427631 | 25388202:25388361 |
| exon_skip_267019 | chr2 | 25383836:25383889:25388202:25388361:25419515:25419535 | 25388202:25388361 |
| exon_skip_27143 | chr2 | 25580721:25580826:25596086:25596240:25607236:25607293 | 25596086:25596240 |
| exon_skip_274969 | chr2 | 25628183:25628384:25639014:25639094:25652594:25652660 | 25639014:25639094 |
| exon_skip_280420 | chr2 | 25451551:25451635:25482796:25482873:25531473:25531597 | 25482796:25482873 |
| exon_skip_293195 | chr2 | 25580721:25580826:25628171:25628384:25639014:25639086 | 25628171:25628384 |
| exon_skip_293523 | chr2 | 25383836:25383889:25387289:25387378:25388202:25388361 | 25387289:25387378 |
| exon_skip_40367 | chr2 | 25482796:25482873:25531473:25531597:25576838:25577004 | 25531473:25531597 |
| exon_skip_51695 | chr2 | 25451548:25451635:25482796:25482873:25531473:25531597 | 25482796:25482873 |
| exon_skip_63402 | chr2 | 25451551:25451635:25455405:25455494:25482796:25482873 | 25455405:25455494 |
| exon_skip_76420 | chr2 | 25451548:25451635:25455405:25455494:25482796:25482873 | 25455405:25455494 |
| exon_skip_95410 | chr2 | 25379290:25379323:25383836:25383889:25387289:25387378 | 25383836:25383889 |
| Differentially expressed PSI values of individual exon skipping events in multiple brain tissues between AD and control. |
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| Exon skipping information | Tissue type | Avg(PSIs) in AD | Avg(PSIs) in control | Difference (PSI) | Adj. p-value |
| exon_skip_174434 | Mayo_CB | 4.626829e-01 | 6.151316e-01 | -1.524487e-01 | 7.684476e-05 |
| exon_skip_170073 | Mayo_CB | 6.602439e-01 | 8.068831e-01 | -1.466392e-01 | 5.273484e-05 |
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Open reading frame (ORF) annotation in the exon skipping event for DTNB |
| Open reading frame (ORF) of individual exon skipping events in ROSMAP based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000406818 | 25531473 | 25531597 | Frame-shift |
| ENST00000406818 | 25596086 | 25596240 | Frame-shift |
| ENST00000406818 | 25607236 | 25607321 | Frame-shift |
| ENST00000406818 | 25383836 | 25383889 | In-frame |
| ENST00000406818 | 25387289 | 25387378 | In-frame |
| ENST00000406818 | 25419515 | 25419535 | In-frame |
| ENST00000406818 | 25455405 | 25455494 | In-frame |
| ENST00000406818 | 25482796 | 25482873 | In-frame |
| ENST00000406818 | 25639014 | 25639094 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in MSBB based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000406818 | 25531473 | 25531597 | Frame-shift |
| ENST00000406818 | 25596086 | 25596240 | Frame-shift |
| ENST00000406818 | 25607236 | 25607321 | Frame-shift |
| ENST00000406818 | 25383836 | 25383889 | In-frame |
| ENST00000406818 | 25387289 | 25387378 | In-frame |
| ENST00000406818 | 25419515 | 25419535 | In-frame |
| ENST00000406818 | 25455405 | 25455494 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in Mayo based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000406818 | 25652594 | 25652661 | 3UTR-3CDS |
| ENST00000406818 | 25427535 | 25427631 | Frame-shift |
| ENST00000406818 | 25531473 | 25531597 | Frame-shift |
| ENST00000406818 | 25596086 | 25596240 | Frame-shift |
| ENST00000406818 | 25607236 | 25607321 | Frame-shift |
| ENST00000406818 | 25628171 | 25628384 | Frame-shift |
| ENST00000406818 | 25383836 | 25383889 | In-frame |
| ENST00000406818 | 25387289 | 25387378 | In-frame |
| ENST00000406818 | 25419515 | 25419535 | In-frame |
| ENST00000406818 | 25432886 | 25432999 | In-frame |
| ENST00000406818 | 25455405 | 25455494 | In-frame |
| ENST00000406818 | 25482796 | 25482873 | In-frame |
| ENST00000406818 | 25639014 | 25639094 | In-frame |
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Infer the effects of exon skipping event on protein functional features for DTNB |
p-ENSG00000138101_img4.png |
| Loci of skipped exons in ROSMAP across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000406818 | 2491 | 627 | 25639014 | 25639094 | 318 | 397 | 22 | 49 |
| ENST00000406818 | 2491 | 627 | 25482796 | 25482873 | 1252 | 1328 | 334 | 359 |
| ENST00000406818 | 2491 | 627 | 25455405 | 25455494 | 1330 | 1418 | 360 | 389 |
| ENST00000406818 | 2491 | 627 | 25387289 | 25387378 | 1986 | 2074 | 578 | 608 |
| ENST00000406818 | 2491 | 627 | 25383836 | 25383889 | 2076 | 2128 | 608 | 626 |
| Loci of skipped exons in MSBB across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000406818 | 2491 | 627 | 25455405 | 25455494 | 1330 | 1418 | 360 | 389 |
| ENST00000406818 | 2491 | 627 | 25387289 | 25387378 | 1986 | 2074 | 578 | 608 |
| ENST00000406818 | 2491 | 627 | 25383836 | 25383889 | 2076 | 2128 | 608 | 626 |
| Loci of skipped exons in Mayo across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000406818 | 2491 | 627 | 25639014 | 25639094 | 318 | 397 | 22 | 49 |
| ENST00000406818 | 2491 | 627 | 25482796 | 25482873 | 1252 | 1328 | 334 | 359 |
| ENST00000406818 | 2491 | 627 | 25455405 | 25455494 | 1330 | 1418 | 360 | 389 |
| ENST00000406818 | 2491 | 627 | 25432886 | 25432999 | 1594 | 1706 | 448 | 485 |
| ENST00000406818 | 2491 | 627 | 25387289 | 25387378 | 1986 | 2074 | 578 | 608 |
| ENST00000406818 | 2491 | 627 | 25383836 | 25383889 | 2076 | 2128 | 608 | 626 |
| Lost protein functional features of individual exon skipping events in ROSMAP. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O60941 | 22 | 49 | 1 | 57 | Alternative sequence | ID=VSP_045534;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| O60941 | 22 | 49 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 334 | 359 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 360 | 389 | 360 | 390 | Alternative sequence | ID=VSP_004223;Note=In isoform 2 and isoform 5. RLQYSQDIPSHLADEHALIASYVARLQHCAR->S;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3;Dbxref=PMID:15489334,PMID:9540997 |
| O60941 | 360 | 389 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 578 | 608 | 559 | 627 | Alternative sequence | ID=VSP_004225;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9540997;Dbxref=PMID:9540997 |
| O60941 | 578 | 608 | 579 | 608 | Alternative sequence | ID=VSP_004226;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3,ECO:0000303|Ref.8;Dbxref=PMID:15489334,PMID |
| O60941 | 578 | 608 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 608 | 626 | 559 | 627 | Alternative sequence | ID=VSP_004225;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9540997;Dbxref=PMID:9540997 |
| O60941 | 608 | 626 | 579 | 608 | Alternative sequence | ID=VSP_004226;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3,ECO:0000303|Ref.8;Dbxref=PMID:15489334,PMID |
| O60941 | 608 | 626 | 609 | 626 | Alternative sequence | ID=VSP_045535;Note=In isoform 6 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334;Dbxref=PMID:14702039,PMID:15489334 |
| O60941 | 608 | 626 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| Lost protein functional features of individual exon skipping events in MSBB. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O60941 | 360 | 389 | 360 | 390 | Alternative sequence | ID=VSP_004223;Note=In isoform 2 and isoform 5. RLQYSQDIPSHLADEHALIASYVARLQHCAR->S;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3;Dbxref=PMID:15489334,PMID:9540997 |
| O60941 | 360 | 389 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 578 | 608 | 559 | 627 | Alternative sequence | ID=VSP_004225;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9540997;Dbxref=PMID:9540997 |
| O60941 | 578 | 608 | 579 | 608 | Alternative sequence | ID=VSP_004226;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3,ECO:0000303|Ref.8;Dbxref=PMID:15489334,PMID |
| O60941 | 578 | 608 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 608 | 626 | 559 | 627 | Alternative sequence | ID=VSP_004225;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9540997;Dbxref=PMID:9540997 |
| O60941 | 608 | 626 | 579 | 608 | Alternative sequence | ID=VSP_004226;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3,ECO:0000303|Ref.8;Dbxref=PMID:15489334,PMID |
| O60941 | 608 | 626 | 609 | 626 | Alternative sequence | ID=VSP_045535;Note=In isoform 6 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334;Dbxref=PMID:14702039,PMID:15489334 |
| O60941 | 608 | 626 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| Lost protein functional features of individual exon skipping events in Mayo. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O60941 | 22 | 49 | 1 | 57 | Alternative sequence | ID=VSP_045534;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039 |
| O60941 | 22 | 49 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 334 | 359 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 360 | 389 | 360 | 390 | Alternative sequence | ID=VSP_004223;Note=In isoform 2 and isoform 5. RLQYSQDIPSHLADEHALIASYVARLQHCAR->S;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3;Dbxref=PMID:15489334,PMID:9540997 |
| O60941 | 360 | 389 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 448 | 485 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 448 | 485 | 428 | 529 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O60941 | 448 | 485 | 399 | 448 | Region | Note=Syntrophin-binding region |
| O60941 | 578 | 608 | 559 | 627 | Alternative sequence | ID=VSP_004225;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9540997;Dbxref=PMID:9540997 |
| O60941 | 578 | 608 | 579 | 608 | Alternative sequence | ID=VSP_004226;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3,ECO:0000303|Ref.8;Dbxref=PMID:15489334,PMID |
| O60941 | 578 | 608 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
| O60941 | 608 | 626 | 559 | 627 | Alternative sequence | ID=VSP_004225;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:9540997;Dbxref=PMID:9540997 |
| O60941 | 608 | 626 | 579 | 608 | Alternative sequence | ID=VSP_004226;Note=In isoform 2%2C isoform 4 and isoform 5. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:15489334,ECO:0000303|PubMed:9540997,ECO:0000303|Ref.3,ECO:0000303|Ref.8;Dbxref=PMID:15489334,PMID |
| O60941 | 608 | 626 | 609 | 626 | Alternative sequence | ID=VSP_045535;Note=In isoform 6 and isoform 7. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334;Dbxref=PMID:14702039,PMID:15489334 |
| O60941 | 608 | 626 | 1 | 627 | Chain | ID=PRO_0000086878;Note=Dystrobrevin beta |
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3'-UTR located exon skipping events that lost miRNA binding sites in DTNB |
| 3'-UTR exon skipping evnets lost miRNA binding. |
| Tissue type | ENST | Exon skip start | Exon skip end | microRNA | Binding site by TargetScan | Binding type by TargetScan | Bdinding site by miRanda | Score of miRanda | Energy by miRanda |
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SNVs in the skipped exons for DTNB |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Depth of Coverage in the skipped exon of the mutated samples. |
| - Sashimi plot in the skipped exon of the mutated samples. |
| - Non-synonymous mutations located in the skipped exons. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
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AD stage-associated exon skippint events for DTNB |
| Associated exon skipping events with Braak staging or Clinical Dementia Rating (CDR). |
| AD stage info | Cohort | Tissue | SE id | Coefficient | P-value | Chromosome | Strand | E1 start | E1 end | Skipped start | Skipped end | E2 start | E2 end |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for DTNB |
| sQTL information located at the skipped exons. |
| Tissue type | Exon skip ID | SNP id | Location | P-value | FDR |
| CB | exon_skip_174434 | rs6746082 | chr2:25436375 | 4.382289e-05 | 8.789695e-03 |
| CB | exon_skip_170073 | rs6746082 | chr2:25436375 | 4.496477e-05 | 8.997415e-03 |
| TC | exon_skip_63402 | rs6546199 | chr2:25460578 | 4.256941e-05 | 8.236994e-03 |
| HCC | exon_skip_170073 | rs1006752 | chr2:25441122 | 3.731118e-04 | 2.688712e-02 |
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Correlation with RNA binding proteins (RBPs) for DTNB |
| Correlated RBP and related information. |
| Tissue type | RBP name | Exon skip ID | Correlation coeifficient | P-value |
| CB | RBM3 | exon_skip_174434 | 5.109984e-01 | 6.880100e-12 |
| CB | TRA2A | exon_skip_174434 | -4.527991e-01 | 2.323714e-09 |
| CB | RBM6 | exon_skip_170073 | -4.373394e-01 | 8.210370e-09 |
| CB | RBM3 | exon_skip_170073 | 4.942786e-01 | 3.557679e-11 |
| CB | PCBP4 | exon_skip_170073 | 5.383117e-01 | 2.512905e-13 |
| DLPFC | RBM3 | exon_skip_174434 | 4.915064e-01 | 1.024919e-21 |
| FL | MSI1 | exon_skip_23988 | -4.321614e-01 | 7.855965e-08 |
| FL | ELAVL4 | exon_skip_23988 | 4.742303e-01 | 2.496888e-09 |
| FL | FXR2 | exon_skip_23988 | 4.059859e-01 | 5.366675e-07 |
| FL | ILF2 | exon_skip_23988 | 4.305408e-01 | 8.890798e-08 |
| FL | RALYL | exon_skip_23988 | 4.596137e-01 | 8.727812e-09 |
| FL | SRSF9 | exon_skip_23988 | 4.541092e-01 | 1.377402e-08 |
| HCC | RBM5 | exon_skip_239173 | -4.428163e-01 | 1.926493e-14 |
| IFG | NOVA1 | exon_skip_170073 | -4.801623e-01 | 1.125045e-02 |
| IFG | RBMS2 | exon_skip_27143 | -4.015748e-01 | 3.416338e-02 |
| IFG | BOLL | exon_skip_23988 | -4.685419e-01 | 1.190998e-02 |
| IFG | ILF2 | exon_skip_23988 | 6.263287e-01 | 3.631030e-04 |
| IFG | EIF4B | exon_skip_23988 | 4.500962e-01 | 1.624665e-02 |
| IFG | HNRNPF | exon_skip_23988 | 4.329969e-01 | 2.135992e-02 |
| PCC | RBM3 | exon_skip_174434 | 4.593219e-01 | 1.273953e-11 |
| PCC | RBFOX2 | exon_skip_76420 | -5.899562e-01 | 3.566662e-21 |
| TC | RBM3 | exon_skip_174434 | 4.412181e-01 | 1.019875e-08 |
| TC | NUP42 | exon_skip_239173 | 6.130721e-01 | 6.877573e-18 |
| TC | SRSF2 | exon_skip_63402 | -4.070364e-01 | 9.223254e-08 |
| TC | RBFOX2 | exon_skip_63402 | -6.828087e-01 | 2.664993e-23 |
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RelatedDrugs for DTNB |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DTNB |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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